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Apoptosome Illustration and Icon
Apoptosome
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A stylized molecular diagram shows a wheel-like heptameric protein complex with a central blue ring and radial connectors binding peripheral green enzyme subunits. In cell biology and biochemistry, this protein complex represents a cytosolic signaling assembly within animal cells. At the molecular hierarchy, it is a multiprotein complex that recruits and activates caspase-9 (CASP9) via Apaf‑1 (apoptotic protease activating factor 1) CARD interactions, initiating the intrinsic apoptosis pathway after cytochrome c (CYCS) and dATP binding.
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