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Allopregnanolone molecule Illustration and Icon
Allopregnanolone molecule
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A skeletal chemical diagram of a C21 neurosteroid (3α-hydroxy-5α-pregnan-20-one) with a four-ring pregnane backbone, a 3α-hydroxyl group, and a 20-ketone. In biological hierarchy, this small molecule acts at the cellular level within the central nervous system (CNS) as a positive allosteric modulator of the GABA_A receptor (GABAAR), shaping inhibitory synaptic transmission. Fields: biochemistry and neuropharmacology. Endogenous in Homo sapiens (human) and other mammals.
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