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Action potential graphic Illustration and Icon
Action potential graphic
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A monochrome electrophysiological trace shows membrane potential (Vm) over time with a small pre-potential, rapid depolarization to a sharp peak, repolarization, and an afterhyperpolarization returning to baseline. The waveform depicts a neuronal action potential (AP) generated by ion flux through voltage-gated sodium channels (VGSCs) and voltage-gated potassium channels (VGKCs) in the axonal membrane of a neuron, a cell within nervous tissue of the nervous system. A dotted trace indicates a lower-amplitude response. In neurophysiology and electrophysiology, the AP enables rapid signal conduction and synaptic communication.
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