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Iodothyronine deiodinase structure Illustration and Icon
Iodothyronine deiodinase structure
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Iodothyronine deiodinase structure. A ribbon diagram shows the tertiary fold of a deiodinase enzyme with alpha helices and beta strands linked by flexible loops. In structural biology and biochemistry, this protein (iodothyronine deiodinase, DIO) catalyzes the deiodination of thyroid hormones, converting thyroxine (T4) to triiodothyronine (T3) or reverse T3, thereby regulating endocrine signaling. Members of this enzyme family are selenoproteins containing the catalytic residue selenocysteine (Sec). At a hierarchical level, it depicts a protein molecule that functions within the endocrine system’s hormone metabolism.
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