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Vcam vascular cell adhesion molecule Illustration and Icon
Vcam vascular cell adhesion molecule
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Conceptual icon representing VCAM-1 (Vascular Cell Adhesion Molecule 1), a transmembrane cell adhesion protein of the immunoglobulin superfamily on the luminal surface of vascular endothelial cells. In biological hierarchy, the molecule is embedded in the plasma membrane of an endothelial cell within the blood vessel wall. In immunology and vascular biology, VCAM-1 mediates leukocyte adhesion by binding α4β1 integrin (VLA-4), supporting rolling, firm arrest, and transendothelial migration during inflammation and contributing to tissue-specific immune trafficking.
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