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Fv immunoglobulin element Illustration and Icon
Fv immunoglobulin element
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A schematic representing the antibody variable fragment composed of two immunoglobulin domains. The upper blue capsule indicates VH (variable heavy chain domain) and the lower green capsule indicates VL (variable light chain domain). In the hierarchy, VH and VL form the Fv fragment within the Fab (fragment antigen-binding, Fab) region of an Ig (immunoglobulin) molecule. In immunology and structural biochemistry, this protein module mediates antigen recognition and generates the paratope that confers binding specificity.
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