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Erbb2 receptor Illustration and Icon
Erbb2 receptor
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Stylized schematic of a dimeric receptor tyrosine kinase (RTK) from the ErbB/epidermal growth factor receptor (EGFR) family, showing two single-pass membrane proteins with curved extracellular domains, paired transmembrane helices, and short cytoplasmic regions. The depiction conveys ligand-independent dimerization and signal transduction via autophosphorylation at the inner face of the plasma membrane, mediating pathways that regulate cell proliferation and survival in cellular and molecular biology and oncology.
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