{"id":16670,"date":"2022-09-16T19:40:00","date_gmt":"2022-09-16T22:40:00","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=16670"},"modified":"2023-03-17T14:47:16","modified_gmt":"2023-03-17T17:47:16","slug":"success-case-nuclear-receptors-in-liver-fibrosis","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/zh\/%e6%88%90%e5%8a%9f%e6%a1%88%e4%be%8b-%e8%82%9d%e7%ba%a4%e7%bb%b4%e5%8c%96%e4%b8%ad%e7%9a%84%e6%a0%b8%e5%8f%97%e4%bd%93\/","title":{"rendered":"\u6838\u53d7\u4f53\u5728\u809d\u810f\u7ea4\u7ef4\u5316\u4e2d\u7684\u4f5c\u7528 \u8bba\u6587\u56de\u987e"},"content":{"rendered":"<p>\u5728\u8fd9\u4e2a\u6848\u4f8b\u4e2d\uff0c\u4f5c\u8005\u4f7f\u7528Mind the Graph\u5c06\u4e0d\u540c\u6765\u6e90\u7684\u6570\u5b57\u6c47\u7f16\u5230\u4e00\u4e2a\u5730\u65b9\u5c31\u53ef\u4ee5\u4e86\u3002\u9664\u4e86\u6700\u597d\u7684\u79d1\u5b66\u51c6\u786e\u7684\u63d2\u56fe\u4e4b\u5916\uff0c\u6211\u4eec\u7684\u5de5\u4f5c\u533a\u6709\u4e00\u4e2a\u53cb\u597d\u7684\u754c\u9762\uff0c\u975e\u5e38\u5bb9\u6613\u4f7f\u7528\u3002<\/p>\n\n\n\n<p>\u68c0\u67e5\u5b8c\u6574\u7684 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S092544392100168X?via%3Dihub\" target=\"_blank\" rel=\"noreferrer noopener\">\u539f\u6587<\/a>. <\/p>\n\n\n\n<h2><strong>\u6838\u53d7\u4f53\u5728\u809d\u810f\u7ea4\u7ef4\u5316\u4e2d\u7684\u4f5c\u7528<\/strong><\/h2>\n\n\n\n<p>Philipp K\u00f6nigshofer\u7b49\u4eba\uff082021\u5e74\uff09\u62a5\u544a\u8bf4\uff0c\u6838\u53d7\u4f53\u662f\u914d\u4f53\u6fc0\u6d3b\u7684\u8f6c\u5f55\u56e0\u5b50\uff0c\u8c03\u8282\u53c2\u4e0e\u809d\u7ea4\u7ef4\u5316\u7684\u5404\u79cd\u5173\u952e\u5206\u5b50\u4fe1\u53f7\u7684\u57fa\u56e0\u8868\u8fbe\u3002 <\/p>\n\n\n\n<p>\u809d\u810f\u7ea4\u7ef4\u5316\u7684\u4e3b\u8981\u7ec6\u80de\u9a71\u52a8\u529b\u662f\u6fc0\u6d3b\u7684\u809d\u661f\u72b6\u7ec6\u80de\u3002\u4e0d\u540c\u7684\u6838\u53d7\u4f53\u8c03\u8282\u809d\u810f\u8868\u8fbe\u4fc3\u708e\u75c7\u548c\u4fc3\u7ea4\u7ef4\u5316\u7684\u7ec6\u80de\u56e0\u5b50\u3002<\/p>\n\n\n\n<h2><strong>\u7531Mind the Graph\u63d0\u4f9b\u7684\u56fe\u5f62\u5316\u6458\u8981<\/strong> <strong>\u5728\u672c\u6761\u4e2d<\/strong><\/h2>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/1-s20-s092544392100168x-gr1.jpg\"><img decoding=\"async\" loading=\"lazy\" width=\"800\" height=\"389\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/1-s20-s092544392100168x-gr1.jpg\" alt=\"\" class=\"wp-image-20242\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/1-s20-s092544392100168x-gr1.jpg 800w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/1-s20-s092544392100168x-gr1-300x146.jpg 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/1-s20-s092544392100168x-gr1-768x373.jpg 768w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/1-s20-s092544392100168x-gr1-18x9.jpg 18w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/1-s20-s092544392100168x-gr1-100x49.jpg 100w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/a><figcaption class=\"wp-element-caption\"><em>\u4f7f\u7528\u65b9\u6cd5 <a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>\u8fd9\u7b2c\u4e00\u5f20\u56fe\u662f\u6838\u53d7\u4f53\u7684\u6982\u8ff0\u548c\u4e9a\u5bb6\u65cf\u7684\u5206\u7c7b\u3002<\/p>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/1-s20-s092544392100168x-gr2.jpg\"><img decoding=\"async\" loading=\"lazy\" width=\"800\" height=\"468\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/1-s20-s092544392100168x-gr2.jpg\" alt=\"\" class=\"wp-image-20246\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/1-s20-s092544392100168x-gr2.jpg 800w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/1-s20-s092544392100168x-gr2-300x176.jpg 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/1-s20-s092544392100168x-gr2-768x449.jpg 768w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/1-s20-s092544392100168x-gr2-18x12.jpg 18w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/1-s20-s092544392100168x-gr2-100x59.jpg 100w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/a><figcaption class=\"wp-element-caption\"><em>\u4f7f\u7528\u65b9\u6cd5 <a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>\u4ee5\u4e0a\u6211\u4eec\u53ef\u4ee5\u770b\u5230\u4e0d\u540c\u7c7b\u578b\u7684\u6838\u53d7\u4f53\u6548\u5e94\u5668\u529f\u80fd\u3002<\/p>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/1-s2.0-S092544392100168X-gr3.jpg\"><img decoding=\"async\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/1-s2.0-S092544392100168X-gr3.jpg\" alt=\"\" class=\"wp-image-20245\"\/><\/a><figcaption class=\"wp-element-caption\"><em>\u4f7f\u7528\u65b9\u6cd5 <a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>\u5728\u7b2c\u4e09\u5f20\u56fe\u4e2d\uff0c\u6211\u4eec\u53ef\u4ee5\u67e5\u770b\u5230NR\u8c03\u8282\u4f5c\u4e3a\u6f5c\u5728\u7684\u6cbb\u7597\u65b9\u6cd5\u5bf9\u809d\u810f\u75be\u75c5\u7684\u5f71\u54cd\u7684\u6982\u8ff0\u3002 <\/p>\n\n\n\n<p>\u7bad\u5934\u8868\u793a\u63a8\u6d4b\u7684\u5bf9\u809d\u810f\u75be\u75c5\u7684\u6709\u76ca\u5f71\u54cd\uff0c\u7531 <span style=\"color:#0d880f\" class=\"has-inline-color\"><strong>\u4e0a-\uff08\u6df1\u7eff\u8272\uff09<\/strong><\/span> \u6216<strong><span class=\"has-inline-color has-vivid-green-cyan-color\"> \u4e0b-\uff08\u6d45\u7eff\u8272\uff09<\/span><\/strong> \u8c03\u8282\u7279\u5b9a\u7684\u673a\u5236\uff0c\u636e\u62a5\u9053\uff0c\u8fd9\u4e9b\u673a\u5236\u652f\u6301\u809d\u810f\u7ea4\u7ef4\u5316\u7684\u6d88\u9000\u6216\u51cf\u5c11\u809d\u810f\u7ea4\u7ef4\u5316\u3002 <\/p>\n\n\n\n<p><strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-luminous-vivid-orange-color\">\u6a59\u8272\u7bad\u5934<\/mark><\/strong> \u8868\u660eNR\u8c03\u8282\u7684\u6548\u679c\u548c\u673a\u5236\u662f\u6709\u4e89\u8bae\u7684\uff0c\u6216\u5c1a\u672a\u5f97\u5230\u5145\u5206\u7684\u8bc4\u4f30\u3002<\/p>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/1-s20-s092544392100168x-gr5.jpg\"><img decoding=\"async\" loading=\"lazy\" width=\"800\" height=\"431\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/1-s20-s092544392100168x-gr5.jpg\" alt=\"\" class=\"wp-image-20244\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/1-s20-s092544392100168x-gr5.jpg 800w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/1-s20-s092544392100168x-gr5-300x162.jpg 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/1-s20-s092544392100168x-gr5-768x414.jpg 768w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/1-s20-s092544392100168x-gr5-18x10.jpg 18w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/1-s20-s092544392100168x-gr5-100x54.jpg 100w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/a><figcaption class=\"wp-element-caption\"><em>\u4f7f\u7528\u65b9\u6cd5 <a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>\u6700\u540e\u4e00\u4e2a\u56fe\u8868\u793aNR\u8c03\u8282\u5242\u4f5c\u4e3a\u809d\u810f\u7ea4\u7ef4\u5316\u7684\u6f5c\u5728\u6cbb\u7597\u65b9\u6cd5\u7684\u5206\u5b50\u6548\u5e94\uff0c\u636e\u62a5\u9053\u8fd9\u4e9b\u6548\u5e94\u4e3b\u8981\u53d1\u751f\u5728\u9020\u8840\u5e72\u7ec6\u80de\u5185\u3002<\/p>\n\n\n\n<p>K\u00f6nigshofer\u53ca\u5176\u540c\u4e8b\u63d0\u51fa\uff0c\u5bf9\u6838\u53d7\u4f53\u76f8\u5173\u4fe1\u53f7\u7684\u8fdb\u4e00\u6b65\u7814\u7a76\u53ef\u80fd\u4f1a\u5bfc\u81f4\u5bf9\u809d\u75c5\u60a3\u8005\u6709\u6548\u6297\u7ea4\u7ef4\u5316\u7597\u6cd5\u7684\u4e34\u5e8a\u5f00\u53d1\u3002<\/p>\n\n\n\n<h2><strong>\u8bba\u6587\u7684\u5f71\u54cd\u548c\u8868\u73b0<\/strong><\/h2>\n\n\n\n<p>\u9009\u62e91\u5e74\u671f\u7684\u6307\u6807\u4e0e\u8be5\u6742\u5fd7\u540c\u4e00\u65e5\u5386\u5e74\u53d1\u8868\u7684\u5176\u4ed6\u6587\u7ae0\/\u8bc4\u8bba\u8fdb\u884c\u6bd4\u8f83\uff0c\u6211\u4eec\u53ef\u4ee5\u53d1\u73b0 <strong>\u8fd9\u7bc7\u6587\u7ae0\u88ab\u5f15\u7528\u7684\u6b21\u6570\u6bd457%\u7684\u8fd8\u591a<\/strong>.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/Nuclear-receptors.png\"><img decoding=\"async\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/Nuclear-receptors.png\" alt=\"\" class=\"wp-image-20247\"\/><\/a><figcaption class=\"wp-element-caption\"><em>\u6765\u6e90 <a href=\"https:\/\/plu.mx\/plum\/a\/?doi=10.1016\/j.bbadis.2021.166235&amp;theme=plum-sciencedirect-theme&amp;hideUsage=true\" target=\"_blank\" rel=\"noreferrer noopener\">\u6885\u82b1X<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>\u5229\u7528\u4fe1\u606f\u56fe\u8868\u7684\u529b\u91cf\uff0c\u4e5f\u53ef\u4ee5\u63d0\u5347\u4f60\u7684\u6587\u7ae0\u3002\u8bd5\u8bd5Mind the Graph!<\/p>\n\n\n\n<div class=\"is-layout-flex wp-block-buttons\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-background wp-element-button\" href=\"https:\/\/mindthegraph.com\/app\/auth\/register?from_url=\/\" style=\"border-radius:100px;background-color:#dc1866\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>\u5c1d\u8bd5Mind the Graph<\/strong><\/a><\/div>\n<\/div>\n\n\n\n<div style=\"height:46px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>","protected":false},"excerpt":{"rendered":"<p>\u672c\u6587\u6709\u7528Mind the Graph\u5236\u4f5c\u7684\u79d1\u5b66\u63d2\u56fe\uff0c\u4ee3\u8868\u809d\u7ea4\u7ef4\u5316\u4e2d\u7684\u6838\u53d7\u4f53\u3002<\/p>","protected":false},"author":29,"featured_media":20044,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[195,958,957,960,1],"tags":[96,554,775,963],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Nuclear receptors in liver fibrosis Paper Review - Mind the Graph Blog<\/title>\n<meta name=\"description\" content=\"This article has scientific illustrations made with Mind the Graph to represent nuclear receptors in liver fibrosis.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mindthegraph.com\/blog\/zh\/\u6210\u529f\u6848\u4f8b-\u809d\u7ea4\u7ef4\u5316\u4e2d\u7684\u6838\u53d7\u4f53\/\" \/>\n<meta property=\"og:locale\" content=\"zh_CN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Nuclear receptors in liver fibrosis Paper Review - Mind the Graph Blog\" \/>\n<meta property=\"og:description\" content=\"This article has scientific illustrations made with Mind the Graph to represent nuclear receptors in liver fibrosis.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/mindthegraph.com\/blog\/zh\/\u6210\u529f\u6848\u4f8b-\u809d\u7ea4\u7ef4\u5316\u4e2d\u7684\u6838\u53d7\u4f53\/\" \/>\n<meta property=\"og:site_name\" content=\"Mind the Graph Blog\" \/>\n<meta property=\"article:published_time\" content=\"2022-09-16T22:40:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-03-17T17:47:16+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/blog_7.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1125\" \/>\n\t<meta property=\"og:image:height\" content=\"614\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Artur Zignani\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:image\" content=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/blog_7.jpg\" \/>\n<meta name=\"twitter:label1\" content=\"\u4f5c\u8005\" \/>\n\t<meta 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