{"id":16662,"date":"2022-09-22T19:23:00","date_gmt":"2022-09-22T22:23:00","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=16662"},"modified":"2023-03-17T14:46:01","modified_gmt":"2023-03-17T17:46:01","slug":"success-case-nmda-receptor-adjusted-co-administration-of-ecstasy-and-cannabinoid-receptor-1-agonist","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/zh\/%e6%88%90%e5%8a%9f%e6%a1%88%e4%be%8b-nmda-%e5%8f%97%e4%bd%93%e8%b0%83%e6%95%b4-ecstasy-and-cannabinoid-receptor-1-agonist%e7%9a%84%e8%81%94%e5%90%88%e7%94%a8%e8%8d%af\/","title":{"rendered":"NMDA\u53d7\u4f53\u901a\u8fc7\u523a\u6fc0\u6210\u5e74\u96c4\u6027\u5927\u9f20\u7684BDNF\/Trk-B\/CREB\u9014\u5f84\u8c03\u6574\u6447\u5934\u4e38\u548c\u5927\u9ebb\u53d7\u4f53-1\u6fc0\u52a8\u5242\u5728\u674f\u4ec1\u6838\u4e2d\u7684\u5171\u540c\u65bd\u7528 \u8bba\u6587\u70b9\u8bc4"},"content":{"rendered":"

\u56fe\u5f62\u5316\u6458\u8981\u5728\u5b66\u672f\u754c\u4e2d\u53d8\u5f97\u975e\u5e38\u6d41\u884c\u3002\u4e5f\u5c31\u662f\u8bf4\uff0c\u4f5c\u8005\u521b\u9020\u4e86\u4e00\u4e2a\u60ca\u4eba\u7684\u8bbe\u8ba1\uff0c\u7528\u51c6\u786e\u7684\u56fe\u50cf\u6765\u89e3\u91ca\u8fd9\u7bc7\u6587\u7ae0\u7684\u6574\u4e2a\u8981\u70b9\u3002<\/p>\n\n\n\n

\u68c0\u67e5\u5b8c\u6574\u7684 \u539f\u6587<\/a>.<\/p>\n\n\n\n

\u98df\u7528\u9009\u62e9\u6027CB-1\u6fc0\u52a8\u5242\u5982ACPA\u53ef\u4fdd\u62a4\u795e\u7ecf\u5143\u514d\u53d7\u674f\u4ec1\u6838\u4e2d\u7684MDMA\u6bd2\u6027\u5f71\u54cd<\/strong><\/h2>\n\n\n\n

\u5728 \"NMDA\u53d7\u4f53\u901a\u8fc7\u523a\u6fc0\u6210\u5e74\u96c4\u6027\u5927\u9f20\u7684BDNF\/Trk-B\/CREB\u9014\u5f84\u8c03\u6574\u6447\u5934\u4e38\u548c\u5927\u9ebb\u53d7\u4f53-1\u6fc0\u52a8\u5242\u5728\u674f\u4ec1\u6838\u7684\u5171\u540c\u7ed9\u836f \"\u4e2d\uff0cAshabi\u53ca\u5176\u540c\u4e8b\uff082017\uff09\u6307\u51fa\uff0cNMDA\u963b\u65ad\u964d\u4f4e\u4e86MDMA\u548cCB1\u53d7\u4f53\u6fc0\u52a8\u5242\u5171\u540c\u6ce8\u5c04\u7684\u5927\u9f20\u7684\u795e\u7ecf\u5143\u53d1\u5c04\u7387\u548c\u916a\u6c28\u9178\u6fc0\u9176B\/\u8111\u6e90\u6027\u795e\u7ecf\u8425\u517b\u56e0\u5b50\/AMP\u53cd\u5e94\u5143\u4ef6\u7ed3\u5408\u86cb\u767d\u6c34\u5e73\u3002 <\/p>\n\n\n\n

\u8c37\u6c28\u9178\u7cfb\u7edf\u901a\u8fc7TrK-B\u53d7\u4f53\u8c03\u63a7MDMA\u548cACPA\u7ec4\u5408\u7684\u4fdd\u62a4\u4f5c\u7528\u3002<\/p>\n\n\n\n

\u7531Mind the Graph\u63d0\u4f9b\u7684\u56fe\u5f62\u5316\u6458\u8981<\/strong><\/h2>\n\n\n\n
\"\"
\u4f7f\u7528\u65b9\u6cd5 Mind the Graph<\/a><\/em><\/figcaption><\/figure>\n\n\n\n

CB1\u53d7\u4f53\u7684\u6fc0\u6d3b\u6216MDMA\u7684\u8bf1\u5bfc\u964d\u4f4e\u4e86\u795e\u7ecf\u5143\u7684\u53d1\u5c04\u7387\u3002\u540c\u65f6\u6ce8\u5c04\u8fd9\u4e24\u79cd\u836f\u7269\u4f1a\u589e\u5f3a\u795e\u7ecf\u5143\u7ec6\u80de\u7684\u5b58\u6d3b\u7387\uff0c\u800c\u8fd9\u4e9b\u4e8b\u4ef6\u901a\u8fc7NMDA\u53d7\u4f53\u62ee\u6297\u5242\u88ab\u9006\u8f6c\u3002 <\/p>\n\n\n\n

\u53ef\u80fd\uff0c\u8c37\u6c28\u9178\u53d7\u4f53\u7684\u4fdd\u62a4\u4f5c\u7528\u53ef\u80fd\u662f\u901a\u8fc7\u6fc0\u6d3bBDNF\/Trk-B\u9014\u5f84\u3002 <\/p>\n\n\n\n

\"\"
\u4f7f\u7528\u65b9\u6cd5 Mind the Graph<\/a><\/em><\/figcaption><\/figure>\n\n\n\n

\u8bba\u6587\u7684\u5f71\u54cd\u548c\u8868\u73b0<\/strong><\/h2>\n\n\n\n

\u9009\u62e91\u5e74\u671f\u7684\u6307\u6807\u4e0e\u8be5\u6742\u5fd7\u540c\u4e00\u65e5\u5386\u5e74\u53d1\u8868\u7684\u5176\u4ed6\u6587\u7ae0\/\u8bc4\u8bba\u8fdb\u884c\u6bd4\u8f83\uff0c\u6211\u4eec\u53ef\u4ee5\u53d1\u73b0 \u8fd9\u7bc7\u6587\u7ae0\u6bd447%\u7684\u5f15\u7528\u7387\u8fd8\u8981\u9ad8<\/strong>.<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

\u5229\u7528\u4fe1\u606f\u56fe\u8868\u7684\u529b\u91cf\uff0c\u4e5f\u53ef\u4ee5\u63d0\u5347\u4f60\u7684\u6587\u7ae0\u3002\u8bd5\u8bd5Mind the Graph!<\/p>","protected":false},"excerpt":{"rendered":"

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