{"id":16621,"date":"2022-09-06T17:57:00","date_gmt":"2022-09-06T20:57:00","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/success-case-psychedelic-assisted-psychotherapy-copy\/"},"modified":"2023-03-17T14:48:05","modified_gmt":"2023-03-17T17:48:05","slug":"success-case-zika-virus-replicates-in-adult-human-brain-tissue-and-impairs-synapses-and-memory-in-mice","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/zh\/%e6%88%90%e5%8a%9f%e6%a1%88%e4%be%8b-%e5%af%a8%e5%8d%a1%e7%97%85%e6%af%92%e5%9c%a8%e6%88%90%e4%ba%ba%e8%84%91%e7%bb%84%e7%bb%87%e4%b8%ad%e5%a4%8d%e5%88%b6%e5%b9%b6%e6%8d%9f%e5%ae%b3%e4%ba%86%e5%b0%8f\/","title":{"rendered":"\u5be8\u5361\u75c5\u6bd2\u5728\u4eba\u7c7b\u6210\u5e74\u8111\u7ec4\u7ec7\u4e2d\u590d\u5236\u5e76\u635f\u5bb3\u5c0f\u9f20\u7684\u7a81\u89e6\u548c\u8bb0\u5fc6 \u8bba\u6587\u70b9\u8bc4"},"content":{"rendered":"

ZIKV\u662f\u4e00\u79cd\u8e42\u8e8f\u4e16\u754c\u7684\u5371\u9669\u75c5\u6bd2\u3002\u56e0\u6b64\uff0c\u5728\u8fd9\u79cd\u60c5\u51b5\u4e0b\uff0c\u4f5c\u8005\u7814\u7a76\u4e86\u5b83\u5728\u6210\u5e74\u4eba\u7c7b\u5927\u8111\u4e2d\u7684\u590d\u5236\u3002<\/p>\n\n\n\n

\u5be8\u5361\u75c5\u6bd2\uff08ZIKV\uff09\u611f\u67d3\u6210\u4eba\u8111\u7ec4\u7ec7\u5e76\u5bfc\u81f4\u5c0f\u9f20\u8bb0\u5fc6\u969c\u788d<\/strong><\/h2>\n\n\n\n

\u7531Claudia Figueiredo\uff082019\u5e74\uff09\u9886\u5bfc\u7684\u836f\u5b66\u9662\u7684\u4e00\u4e2a\u5c0f\u7ec4\u7814\u7a76\u4e86\u5be8\u5361\u75c5\u6bd2\u5982\u4f55\u5728\u6210\u5e74\u4eba\u7c7b\u5927\u8111\u7ec4\u7ec7\u4e2d\u590d\u5236\u5e76\u635f\u5bb3\u5c0f\u9f20\u7684\u7a81\u89e6\u548c\u8bb0\u5fc6\u3002\u5be8\u5361\u75c5\u6bd2\u662f\u4e00\u79cd\u5c5e\u4e8e\u9ec4\u75c5\u6bd2\u79d1\u7684\u866b\u5a92\u75c5\u6bd2\uff0c\u5bf9\u6700\u8fd1\u5728\u62c9\u4e01\u7f8e\u6d32\u7684\u4e00\u6b21\u91cd\u5927\u7206\u53d1\u8d1f\u8d23\u3002 <\/p>\n\n\n\n

\u5728\u6210\u5e74\u60a3\u8005\u7684\u5927\u8111\u548cCSF\u4e2d\u53d1\u73b0\u4e86ZIKV\u3002NS2B\u514d\u75ab\u53cd\u5e94\u6027\u4e0eNeuN\u514d\u75ab\u53cd\u5e94\u6027\u7ec6\u80de\u5171\u5b9a\u4f4d\uff0c\u4f46\u4e0d\u4e0eGFAP\u6216F4\/80\u5171\u5b9a\u4f4d\uff0c\u8868\u660e\u5728\u6210\u719f\u7684\u4eba\u4f53\u7ec4\u7ec7\u4e2d\u795e\u7ecf\u5143\u662fZikV\u7684\u76ee\u6807\u3002\u5728\u901a\u8fc7\u8111\u5ba4\u5185\u8f93\u6ce8ZIKV\u611f\u67d3\u7684\u6210\u5e74\u514d\u75ab\u529f\u80fd\u6b63\u5e38\u7684\u5c0f\u9f20\u4e2d\uff0c\u5728\u989d\u53f6\u76ae\u5c42\u548c\u6d77\u9a6c\u4e2d\u68c0\u6d4b\u5230\u9ad8\u6c34\u5e73\u7684ZikV RNA\uff0c\u6210\u719f\u795e\u7ecf\u5143\u662f\u88ab\u611f\u67d3\u7684\u4e3b\u8981\u7ec6\u80de\u7c7b\u578b\u3002 <\/p>\n\n\n\n

\u8111\u90e8TNF-\u03b1\u6c34\u5e73\u5347\u9ad8\uff0c\u5f3a\u70c8\u7684\u5c0f\u80f6\u8d28\u589e\u751f\uff0c\u8865\u4f53\u7cfb\u7edf\u86cb\u767d\uff08C1q\u548cC3\uff09\u7684\u8868\u8fbe\u4e0a\u8c03\uff0c\u4ee5\u53ca\u6d77\u9a6c\u7a81\u89e6\u635f\u4f24\u90fd\u5f97\u5230\u4e86\u9a8c\u8bc1\u3002<\/p>\n\n\n\n

\u8be5\u7814\u7a76\u6d89\u53ca9\u4e2a\u5e73\u7b49\u7684\u8c61\u9650\u3002<\/strong><\/p>\n\n\n\n

\u68c0\u67e5 \u539f\u6587\u5728\u6b64<\/a>.<\/p>\n\n\n\n

\u7531Mind the Graph\u63d0\u4f9b\u7684\u56fe\u5f62\u5316\u6458\u8981<\/strong><\/h2>\n\n\n\n
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\"\"<\/a>
\u4f7f\u7528\u65b9\u6cd5 Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n

\u7b2c\u4e00\u5f20\u56fe\u8868\u793a\u5c06\u4eba\u7684\u989e\u53f6\u76ae\u5c42\u7ec4\u7ec7\u788e\u7247\u5207\u6210400\u5fae\u7c73\u7684\u7247\u72b6\uff0c\u5728\u7528ZIKV\uff08107PFU\uff09\u6216\u6a21\u62df\u57f9\u517b\u57fa\u57f9\u517b1\u5c0f\u65f6\u4e4b\u524d\uff0c\u5728\u57f9\u517b\u4e2d\u4fdd\u63014\u5929\uff0c\u7136\u540e\u6d17\u6389\u3002 <\/p>\n\n\n\n

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\u4f7f\u7528\u65b9\u6cd5 Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n

\u7b2c\u4e8c\u5f20\u663e\u793a\uff0c\u6210\u5e74\u5c0f\u9f20\u63a5\u53d7105 PFU ZIKV\u3001\u7d2b\u5916\u7ebf\u706d\u6d3b\u7684ZIKV\u6216\u6a21\u62df\u57f9\u517b\u57fa\u6ce8\u5165\u5927\u8111\u4fa7\u8111\u5ba4\u3002<\/p>\n\n\n\n

\u8fd9\u4e9b\u7ed3\u8bba\u4f3c\u4e4e\u652f\u6301\u4e86\u4ee5\u524d\u5bf9\u8fd9\u4e2a\u95ee\u9898\u7684\u8ba4\u8bc6\u3002\"\u65e0\u8bba\u611f\u67d3\u9014\u5f84\u662f\u4e2d\u67a2\u8fd8\u662f\u5916\u5468\uff0cZIKV\u90fd\u9488\u5bf9\u4e0e\u8bb0\u5fc6\u6709\u5173\u7684\u8111\u533a\u3002Figueiredo\u79f0\uff1a\"\u5728\u60a3\u6709\u795e\u7ecf\u7cfb\u7edf\u5e76\u53d1\u75c7\u7684\u6210\u5e74\u60a3\u8005\u7684CSF\u4e2d\u5df2\u7ecf\u68c0\u6d4b\u5230\u4e86\u8be5\u75c5\u6bd2\u3002<\/p>\n\n\n\n

\u4ed6\u4eec\u63d0\u51fa\uff0c\u672a\u6765\u7684\u7814\u7a76\u65e8\u5728\u68c0\u67e5ZIKV\u611f\u67d3\u7684\u957f\u671f\u795e\u7ecf\u9000\u884c\u6027\u5f71\u54cd\uff0c\u662f\u6709\u5fc5\u8981\u7684\u3002\u786e\u5b9a\u9884\u9632\u5bfc\u81f4\u5927\u8111\u529f\u80fd\u969c\u788d\u7684\u4fe1\u53f7\u5f02\u5e38\u7684\u65b9\u6cd5\uff0c\u53ef\u4ee5\u4e3a\u5e72\u9884\u7b56\u7565\u94fa\u5e73\u9053\u8def\uff0c\u4ee5\u63a8\u8fdf\u6216\u9632\u6b62\u4e3b\u8981\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u7684\u53d1\u5c55\u3002<\/p>\n\n\n\n

\u8bba\u6587\u7684\u5f71\u54cd\u548c\u8868\u73b0<\/strong><\/h2>\n\n\n\n

\u6211\u4eec\u53ef\u4ee5\u7528\u4ee5\u4e0b\u65b9\u6cd5\u8fdb\u884c\u5206\u6790 Altmetric<\/a> \u6570\u636e\u663e\u793a\uff0c\u8be5\u8bba\u6587\u7684\u5728\u7ebf\u5173\u6ce8\u5ea6\u5f97\u5206\u66f4\u9ad8 \u6bd4 95%<\/strong><\/strong> \u5728\u300a\u81ea\u7136\u300b\u4e2d\u7c7b\u4f3c\u5e74\u9f84\u7684\u6240\u6709\u5176\u4ed6\u6587\u7ae0\u4e2d\u7684\u6bd4\u4f8b<\/strong> \u671f\u520a\u3002<\/strong><\/p>\n\n\n\n

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\u6765\u6e90 Altmetric<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n

\u4e5f\u8981\u5229\u7528\u4fe1\u606f\u56fe\u8868\u7684\u529b\u91cf\u6765\u63d0\u5347\u4f60\u7684\u6587\u7ae0!\u5728Mind the Graph\u5f00\u59cb\u521b\u4f5c\u3002<\/p>\n\n\n\n

\n
\u5c1d\u8bd5Mind the Graph<\/strong><\/a><\/div>\n<\/div>\n\n\n\n
<\/div>","protected":false},"excerpt":{"rendered":"

\u8fd9\u9879\u7814\u7a76\u662f\u5173\u4e8e\u6210\u5e74\u4eba\u7c7b\u5927\u8111\u4e2d\u7684ZIKV\uff0c\u8fd9\u662f\u4e00\u79cd\u8e42\u8e8f\u4e16\u754c\u7684\u5371\u9669\u75c5\u6bd2\u3002\u8fd9\u4e2a\u8fc7\u7a0b\u4f7f\u7528\u4e86Mind the Graph\u7684\u63d2\u56fe\u3002<\/p>","protected":false},"author":29,"featured_media":20048,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[195,958,957,960,1],"tags":[96,963],"yoast_head":"\nZika virus replicates in adult human brain tissue and impairs synapses and memory in mice Paper Review - Mind the Graph Blog<\/title>\n<meta name=\"description\" content=\"The study is about ZIKV in the adult human brain, a dangerous virus that ravages the world. The process uses Mind the Graph illustrations.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mindthegraph.com\/blog\/zh\/\u6210\u529f\u6848\u4f8b-\u5be8\u5361\u75c5\u6bd2\u5728\u6210\u4eba\u8111\u7ec4\u7ec7\u4e2d\u590d\u5236\u5e76\u635f\u5bb3\u4e86\u5c0f\/\" \/>\n<meta property=\"og:locale\" content=\"zh_CN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Zika virus replicates in adult human brain tissue and impairs synapses and memory in mice Paper Review - Mind the Graph Blog\" \/>\n<meta property=\"og:description\" content=\"The study is about ZIKV in the adult human brain, a dangerous virus that ravages the world. 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