{"id":7254,"date":"2017-06-21T17:35:04","date_gmt":"2017-06-21T20:35:04","guid":{"rendered":"https:\/\/blog.mindthegraph.com\/?p=7254"},"modified":"2022-10-18T08:29:23","modified_gmt":"2022-10-18T11:29:23","slug":"alzheimers-graphical-abstracts","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/tr\/alzheimers-graphical-abstracts\/","title":{"rendered":"Alzheimer'\u0131n grafik \u00f6zetleri: Sinirbilimdeki yenilikler g\u00f6rsel bir \u015fekilde"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Kullan\u0131c\u0131lar\u0131m\u0131za inan\u0131lmaz \u00e7al\u0131\u015fmalar\u0131n\u0131 g\u00f6stermeyi ger\u00e7ekten seviyoruz - \u00f6zellikle de Mind the Graph \u00e7izimlerini ve ara\u00e7lar\u0131n\u0131 kullanarak makale yay\u0131nl\u0131yorlarsa.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Bu y\u00fczden, bug\u00fcn size premium bir kullan\u0131c\u0131n\u0131n ara\u015ft\u0131rmas\u0131n\u0131 grafi\u011fin zihninde g\u00f6sterece\u011fiz, <a href=\"https:\/\/www.researchgate.net\/profile\/Stefania_Forner3\">Stefania Forner<\/a>.  Yak\u0131n zamanda Trends in Neurosciences dergisinde \u015fu ba\u015fl\u0131kl\u0131 bir inceleme makalesi yay\u0131mland\u0131<\/span><b><a href=\"http:\/\/www.cell.com\/trends\/neurosciences\/fulltext\/S0166-2236(17)30069-3?rss=yes\"> Alzheimer Hastal\u0131\u011f\u0131nda sinaptik bozulma: D\u00fczensiz bir senfoni.<\/a> <\/b>\u00a0\u00c7al\u0131\u015fmalar\u0131n\u0131 g\u00f6stermek i\u00e7in iki Alzheimer grafik \u00f6zeti yapt\u0131.<\/p>\n<p style=\"text-align: justify;\"><span style=\"font-weight: 400;\"><strong>\u00d6ncelikle Stefania'n\u0131n \u00e7al\u0131\u015fma alan\u0131n\u0131 biraz tan\u0131tarak ba\u015flayal\u0131m<\/strong>:<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Alzheimer hastal\u0131\u011f\u0131 (AH) bili\u015fsel eksikliklere ve haf\u0131za kayb\u0131na neden olan n\u00f6rodejeneratif bir hastal\u0131kt\u0131r.  AH, ABD'de \u00f6nde gelen alt\u0131nc\u0131 \u00f6l\u00fcm nedenidir ve <strong>35 milyon ki\u015fi<\/strong> d\u00fcnyan\u0131n d\u00f6rt bir yan\u0131nda. <\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-weight: 400;\">Kan\u0131tlar, AD'nin bili\u015fsel eksiklikleri ile sinaps kayb\u0131 aras\u0131nda nedensel bir rol oldu\u011funu g\u00f6stermektedir. Ayr\u0131ca, sinaps disfonksiyonu iki patolojik yolla ili\u015fkili olabilir. H\u00fccre d\u0131\u015f\u0131 birikim <strong>beta-amiloid peptit<\/strong> ve h\u00fccre i\u00e7i birikimi <strong>tau proteini<\/strong>.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-weight: 400;\">Bu iki s\u00fcrecin AH'de \u00f6nemli bir rol oynad\u0131\u011f\u0131 bilinmektedir. Bununla birlikte, geriye kalan en \u00f6nemli temel sorulardan biri, beta-amiloid ve tau aras\u0131ndaki molek\u00fcler ili\u015fki ve bu iki oyuncunun AD'de sinaptik i\u015flevde birbirine ba\u011fl\u0131 olarak nas\u0131l bozulmalara neden oldu\u011fuyla ilgilidir.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-weight: 400;\">Bu nedenle, sinaptik fonksiyon ve AD'de tau proteini ve beta-amiloid peptid etkilerini ayr\u0131 ayr\u0131 analiz etmek i\u00e7in Stefania, Mind the Graph platformunda yapt\u0131\u011f\u0131 iki grafik \u00f6zeti kulland\u0131. Bunlardan biri beta-amiloid oligomerlerinin olu\u015fumunu ve sinaptik toksisite mekanizmalar\u0131n\u0131, di\u011feri ise tau proteini ile n\u00f6ronlardaki sinapslar aras\u0131ndaki ili\u015fkiyi g\u00f6stermek i\u00e7in. \u00a0<\/span><\/p>\n<h2 style=\"text-align: justify;\"><strong>Alzheimer grafik \u00f6zetleri<\/strong><\/h2>\n<p><a href=\"https:\/\/blog.mindthegraph.com\/wp-content\/uploads\/2017\/06\/alzheimer-disorder.png\"><img decoding=\"async\" loading=\"lazy\" class=\"aligncenter wp-image-7255\" src=\"https:\/\/blog.mindthegraph.com\/wp-content\/uploads\/2017\/06\/alzheimer-disorder.png\" alt=\"Alzheimer hastal\u0131\u011f\u0131\" width=\"580\" height=\"473\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2017\/06\/alzheimer-disorder.png 521w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2017\/06\/alzheimer-disorder-300x245.png 300w\" sizes=\"(max-width: 580px) 100vw, 580px\" \/><\/a><\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/blog.mindthegraph.com\/wp-content\/uploads\/2017\/06\/alzheimer-disorder-tau.png\"><img decoding=\"async\" loading=\"lazy\" class=\"aligncenter size-full wp-image-7256\" src=\"https:\/\/blog.mindthegraph.com\/wp-content\/uploads\/2017\/06\/alzheimer-disorder-tau.png\" alt=\"alzheimer-bozuklu\u011fu-tau\" width=\"607\" height=\"609\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2017\/06\/alzheimer-disorder-tau.png 607w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2017\/06\/alzheimer-disorder-tau-150x150.png 150w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2017\/06\/alzheimer-disorder-tau-300x300.png 300w\" sizes=\"(max-width: 607px) 100vw, 607px\" \/><\/a><\/p>\n<p>&nbsp;<\/p>\n<blockquote>\n<p style=\"text-align: right;\">\"\u00d6zellikle, A\u00df, tau ve sinaptik eksiklikler ve\/veya kay\u0131plar aras\u0131ndaki molek\u00fcler ili\u015fkiyi ara\u015ft\u0131ran \u00e7al\u0131\u015fmalar, bu patolojilerin sonu\u00e7ta hastalarda bili\u015fsel gerilemeye nas\u0131l yol a\u00e7abilece\u011fine \u0131\u015f\u0131k tutmu\u015ftur. \u00c7e\u015fitli potansiyel pre- ve postsinaptik yolaklar\u0131n tan\u0131mlanmas\u0131, AD'nin alt\u0131nda yatan klinik semptomlara katk\u0131da bulunabilir.\"<\/p>\n<\/blockquote>\n<h2><\/h2>\n<p>&nbsp;<\/p>\n<h2><b>Ben de ara\u015ft\u0131rmalar\u0131m i\u00e7in grafiksel \u00f6zetler istiyorum!<\/b><\/h2>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">Grafik \u00f6zetler, \u00e7al\u0131\u015fman\u0131z\u0131n ana noktalar\u0131n\u0131 tamamlaman\u0131n ve g\u00f6stermenin bir yoludur. Kendi harika grafik \u00f6zetlerinizi nas\u0131l yapaca\u011f\u0131n\u0131z\u0131 \u00f6\u011frenmek istiyorsan\u0131z, i\u015fte size yard\u0131mc\u0131 olacak birka\u00e7 g\u00f6nderi:<\/span><\/p>\n<ul>\n<li><a href=\"https:\/\/blog.mindthegraph.com\/graphical-abstracts-3-steps\/#.WUrD72grIdU\" target=\"_blank\" rel=\"noopener\">Grafiksel \u00f6zetler: 3 ad\u0131m \u00f6tedesiniz<\/a><\/li>\n<li><a href=\"https:\/\/blog.mindthegraph.com\/improvements\/#.WUrD9mgrIdU\" target=\"_blank\" rel=\"noopener\">Y\u00fckseltmeleri severiz: Her g\u00fcn geli\u015fmek<\/a><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">Mind the Graph'yi \u00fccretsiz olarak kullanmaya ba\u015flayabilirsiniz. Deneyebilece\u011finiz ve bilimsel k\u00fct\u00fcphanemize eri\u015febilece\u011finiz \u00dccretsiz bir s\u00fcr\u00fcm\u00fcm\u00fcz var. Premium kullan\u0131c\u0131lar platforma tam eri\u015fime ve burada g\u00f6rebilece\u011finiz gibi \u00f6zel avantajlara sahiptir.<\/span><\/p>\n<p><a href=\"https:\/\/blog.mindthegraph.com\/wp-content\/uploads\/2016\/10\/start_now.png\"><img decoding=\"async\" loading=\"lazy\" class=\"aligncenter wp-image-6373\" src=\"https:\/\/blog.mindthegraph.com\/wp-content\/uploads\/2016\/10\/start_now.png\" alt=\"infographic63724-3\" width=\"500\" height=\"200\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2016\/10\/start_now.png 1500w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2016\/10\/start_now-300x120.png 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2016\/10\/start_now-768x307.png 768w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2016\/10\/start_now-1024x410.png 1024w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/><\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>Kullan\u0131c\u0131lar\u0131m\u0131z\u0131n inan\u0131lmaz \u00e7al\u0131\u015fmalar\u0131n\u0131 g\u00f6stermeyi ger\u00e7ekten seviyoruz - \u00f6zellikle de Mind the Graph \u00e7izimlerini ve ara\u00e7lar\u0131n\u0131 kullanarak makaleler yay\u0131nl\u0131yorlarsa. Bu nedenle bug\u00fcn size Mind the Graph'in premium kullan\u0131c\u0131lar\u0131ndan Stefania Forner'in ara\u015ft\u0131rmas\u0131n\u0131 g\u00f6sterece\u011fiz.  Yak\u0131n zamanda Trends in Neurosciences dergisinde Alzheimer'da Sinaptik Bozulma ba\u015fl\u0131kl\u0131 bir inceleme makalesi yay\u0131mland\u0131 [...]<\/p>","protected":false},"author":11,"featured_media":7269,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[956],"tags":[214,213,96,554,216,775,215],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Alzheimer&#039;s graphical abstracts: What&#039;s new in neuroscience in a visual way - Mind the Graph Blog<\/title>\n<meta name=\"description\" content=\"Today we\u2019ll show you the research of Stefania Forner. 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