{"id":16651,"date":"2022-09-12T18:50:00","date_gmt":"2022-09-12T21:50:00","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=16651"},"modified":"2023-03-17T14:47:35","modified_gmt":"2023-03-17T17:47:35","slug":"success-case-immunotherapeutic-potential-of-crotoxin-anti-inflammatory-and-immunosuppressive-properties","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/tr\/basari-durumu-immunoterapotik-potansiyel-of-crotoxin-anti-inflamatuar-ve-immunosupresif-ozellikler\/","title":{"rendered":"Crotoxin'in imm\u00fcnoterap\u00f6tik potansiyeli: anti-enflamatuar ve imm\u00fcnosupresif \u00f6zellikler Makale Derlemesi"},"content":{"rendered":"<p>Krotoksinin anti-enflamatuar mod\u00fclasyonunu uygun g\u00f6r\u00fcnt\u00fcler olmadan a\u00e7\u0131klamak biraz zor olabilir, ancak Mind the Graph i\u015fte bu y\u00fczden var!<\/p>\n\n\n\n<h2><strong>\u00c7\u0131ng\u0131rakl\u0131 y\u0131lan zehri olan Crotoxin \u00fczerine yap\u0131lan bilimsel ara\u015ft\u0131rmalar\u0131n g\u00f6zden ge\u00e7irilmesi<\/strong><\/h2>\n\n\n\n<p>Marco Sartim ve arkada\u015flar\u0131 (2018), 'Crotoxin'in imm\u00fcnoterap\u00f6tik potansiyeli' ba\u015fl\u0131kl\u0131 makalelerinde, Crotoxin'in son 80 y\u0131ld\u0131r y\u0131lan zehirlerinden en \u00e7ok ara\u015ft\u0131r\u0131lan izole toksinlerden biri haline geldi\u011fini belirtmi\u015flerdir. <\/p>\n\n\n\n<p>Krotoksin, G\u00fcney Amerika \u00e7\u0131ng\u0131rakl\u0131 y\u0131lan\u0131 Crotalus durissus terrificus'un zehirindeki ana toksik bile\u015fendir. \u00c7al\u0131\u015fmalar, C.d.t.'nin imm\u00fcnomod\u00fclat\u00f6r etkisinin anti-inflamatuar mediat\u00f6rlerin \u00fcretimi ile ili\u015fkili oldu\u011funu g\u00f6stermi\u015ftir. <\/p>\n\n\n\n<p>Crotoxin ve alt birimlerinin ba\u011f\u0131\u015f\u0131kl\u0131k sistemini mod\u00fcle etme kapasitesi, potansiyel terap\u00f6tik ajanlar olarak yeni perspektifler ortaya koymu\u015ftur.<\/p>\n\n\n\n<p><strong>Ara\u015ft\u0131rmac\u0131lar 161 makaleyi incelemi\u015flerdir.<\/strong><\/p>\n\n\n\n<p>Kontrol edin <a href=\"https:\/\/jvat.biomedcentral.com\/articles\/10.1186\/s40409-018-0178-3\" target=\"_blank\" rel=\"noreferrer noopener\">orijinal makale burada<\/a>.<\/p>\n\n\n\n<h2><strong>Mind the Graph taraf\u0131ndan desteklenen Grafiksel \u00d6zetler<\/strong><\/h2>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html.webp\"><img decoding=\"async\" loading=\"lazy\" width=\"1024\" height=\"1003\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-1024x1003.webp\" alt=\"\" class=\"wp-image-20251\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-1024x1003.webp 1024w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-300x294.webp 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-768x752.webp 768w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-12x12.webp 12w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-100x98.webp 100w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html.webp 1418w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><figcaption class=\"wp-element-caption\"><em>ile yap\u0131lm\u0131\u015ft\u0131r <a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>Yazar, enflamatuar uyaran s\u0131ras\u0131nda Crotoxin ve alt birimleri taraf\u0131ndan mod\u00fcle edilen dola\u015f\u0131m, doku ve h\u00fccresel olaylar hakk\u0131nda \u015fematik bir \u015fekil olu\u015fturmak i\u00e7in Mind the Graph platformunu kulland\u0131.<\/p>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_Fig3_HTML.webp\"><img decoding=\"async\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_Fig3_HTML-839x1024.webp\" alt=\"\" class=\"wp-image-20252\"\/><\/a><figcaption class=\"wp-element-caption\"><em>ile yap\u0131lm\u0131\u015ft\u0131r <a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>Yazar ayr\u0131ca kan dola\u015f\u0131m\u0131n\u0131, lenfositlerin lenf d\u00fc\u011f\u00fcm\u00fcne yerle\u015fmesini ve Krotoksin ve alt birimlerinin imm\u00fcnosupresif etkileriyle ili\u015fkili h\u00fccresel olaylar\u0131 da detayland\u0131rm\u0131\u015ft\u0131r.<\/p>\n\n\n\n<p><strong>\u0130\u015fte infografiklerin g\u00fcc\u00fc!<\/strong><\/p>\n\n\n\n<p>Yazarlar\u0131n vard\u0131\u011f\u0131 sonu\u00e7lar, bu alandaki \u00f6nceki \u00e7al\u0131\u015fmalar\u0131 peki\u015ftiriyor gibi g\u00f6r\u00fcnmektedir: Sartim, \"Krotoksin, HAS ile a\u015f\u0131lanm\u0131\u015f farelerden spesifik anti-HSA IgG1 ve IgG2a antikor \u00fcretimini bask\u0131layabildi ve bu da Th1 ve Th2 yan\u0131tlar\u0131n\u0131 mod\u00fcle etme kapasitesini g\u00f6sterdi\" dedi.<\/p>\n\n\n\n<h2><strong>Belgeler Etki ve Performans<\/strong><\/h2>\n\n\n\n<p>ile analiz edebiliriz <a href=\"https:\/\/mindthegraph.com\/blog\/altmetric\/\" target=\"_blank\" rel=\"noreferrer noopener\">Altmetric<\/a> Bu makalenin daha fazla at\u0131f ald\u0131\u011f\u0131 veriler <strong>daha <strong>84%<\/strong><\/strong> <strong>Springer Nature'daki di\u011fer makaleler.<\/strong><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1.png\"><img decoding=\"async\" loading=\"lazy\" width=\"322\" height=\"578\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1.png\" alt=\"\" class=\"wp-image-20254\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1.png 322w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1-167x300.png 167w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1-7x12.png 7w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1-56x100.png 56w\" sizes=\"(max-width: 322px) 100vw, 322px\" \/><\/a><figcaption class=\"wp-element-caption\"><em>Kaynak <a href=\"https:\/\/citations.springernature.com\/item?doi=10.1186\/s40409-018-0178-3&amp;start=11&amp;years=&amp;journals=&amp;books=&amp;authors=\" target=\"_blank\" rel=\"noreferrer noopener\">Crossref<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>\u0130nfografiklerin g\u00fcc\u00fcn\u00fc kullanarak <a href=\"https:\/\/mindthegraph.com\/blog\/research-journal-impact-factor\/\">makalenizi etkileyin<\/a> ayn\u0131 zamanda. Mind the Graph'yi deneyin!<\/p>\n\n\n\n<div class=\"is-layout-flex wp-block-buttons\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-background wp-element-button\" href=\"https:\/\/mindthegraph.com\/app\/auth\/register?from_url=\/\" style=\"border-radius:100px;background-color:#dc1866\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Mind the Graph'yi deneyin<\/strong><\/a><\/div>\n<\/div>\n\n\n\n<div style=\"height:46px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Krotoksinin anti-enflamatuar mod\u00fclasyonunu uygun g\u00f6r\u00fcnt\u00fcler olmadan a\u00e7\u0131klamak biraz zor olabilir, ancak Mind the Graph var!<\/p>","protected":false},"author":29,"featured_media":20047,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[195,958,957,960,1],"tags":[96,554,963],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.9 - 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