{"id":12192,"date":"2021-01-27T10:46:16","date_gmt":"2021-01-27T12:46:16","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=12192"},"modified":"2023-01-05T14:40:18","modified_gmt":"2023-01-05T17:40:18","slug":"cannabis-and-alzheimers-disease","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/tr\/esrar-ve-alzheimers-hastaligi\/","title":{"rendered":"Esrar ve Alzheimer Hastal\u0131\u011f\u0131 Hakk\u0131nda Neler Var?"},"content":{"rendered":"
<\/div>\n\n\n\n
\n
\n
\n
\n

<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

Alzheimer hastal\u0131\u011f\u0131 (AH), g\u00fcn\u00fcm\u00fczde te\u015fhis edilen demans vakalar\u0131n\u0131n 50%'sinden fazlas\u0131ndan sorumlu n\u00f6rodejeneratif bir hastal\u0131kt\u0131r ve ya\u015flanma ile do\u011frudan ili\u015fkilidir. G\u00fcn\u00fcm\u00fczde 85 ya\u015f\u0131n \u00fczerindeki insanlar\u0131n 40%'sinde bir miktar demans g\u00f6r\u00fclmektedir.<\/p>\n\n\n\n

\u00d6nceleri, AD semptomlar\u0131n\u0131n sadece k\u0131sa s\u00fcreli an\u0131lar\u0131 etkileyen bir bili\u015fsel i\u015flev azalmas\u0131yla ilgili oldu\u011fu d\u00fc\u015f\u00fcn\u00fcl\u00fcrken, hastal\u0131\u011f\u0131n ileri a\u015famalar\u0131nda hastan\u0131n dil becerilerini ve hatta uzun s\u00fcreli an\u0131lar\u0131n\u0131 etkiledi\u011fi d\u00fc\u015f\u00fcn\u00fcl\u00fcyordu.<\/p>\n\n\n\n

Ancak g\u00fcn\u00fcm\u00fczde AD'den muzdarip hastalar\u0131n depresyon, psikoz, agresif davran\u0131\u015flar gibi hastal\u0131\u011f\u0131 daha da k\u00f6t\u00fcle\u015ftiren bir dizi ba\u015fka semptom g\u00f6sterdi\u011fi bilinmektedir. <\/p>\n\n\n\n

Son y\u0131llarda, ara\u015ft\u0131rmac\u0131lar ve doktorlar \u00e7al\u0131\u015fmalar\u0131nda, AD hastalar\u0131n\u0131 esrar bazl\u0131 ila\u00e7larla tedavi etmeye ba\u015flad\u0131klar\u0131nda semptomlarda rahatlama sa\u011flayan olumlu sonu\u00e7lar bildirmi\u015flerdir.<\/p>\n\n\n\n

Endokannabinoid sistem, n\u00f6roplastisite, n\u00f6roinflamasyon, davran\u0131\u015f bozukluklar\u0131, uyku d\u00fczenlemesi, imm\u00fcnolojik fonksiyonlar, inflamatuar hastal\u0131klar, kardiyovask\u00fcler fonksiyonlar, a\u011fr\u0131, motor kontrol, enerji dengesi ve i\u015ftah gibi \u00e7e\u015fitli s\u00fcre\u00e7lerdeki etkisinin yan\u0131 s\u0131ra farkl\u0131 hastal\u0131k ve patolojilerin tedavisinde alternatif bir yakla\u015f\u0131m haline gelmi\u015ftir. <\/p>\n\n\n\n

\"\"<\/a>
Foto\u011fraflar Ravi Patel<\/a> \u00fczerinde Unsplash<\/a><\/figcaption><\/figure>\n\n\n\n

Ne yaz\u0131k ki, endokannabinoid sistem ve AD aras\u0131ndaki ili\u015fkiyi do\u011frudan analiz eden az say\u0131da resmi \u00e7al\u0131\u015fma bulunmaktad\u0131r.<\/p>\n\n\n\n

G\u00fcn\u00fcm\u00fczde AD'nin genetik ve ya\u015flanma fakt\u00f6rlerinden kaynakland\u0131\u011f\u0131 iyi bilinmektedir. Hastal\u0131\u011f\u0131n temel su\u00e7lular\u0131 \u015funlara ba\u011flanmaktad\u0131r ya\u015fl\u0131l\u0131k plaklar\u0131<\/strong> ve n\u00f6rofibriler kar\u0131\u015f\u0131k<\/strong>. <\/p>\n\n\n\n

\u0130lgin\u00e7 bir ger\u00e7ek de, ara\u015ft\u0131rmac\u0131lar\u0131n AD s\u0131\u00e7an modellerini kullanarak, AD beyinlerinin sa\u011fl\u0131kl\u0131 beyinlere k\u0131yasla daha az say\u0131da CB1 resept\u00f6r\u00fcne sahip oldu\u011funu ke\u015ffetmeleridir - daha az CB1 resept\u00f6r\u00fc sonu\u00e7ta ilac\u0131n terap\u00f6tik etkisini azaltabilir.<\/p>\n\n\n\n

Kannabinoid tedavisi, Alzheimer hastal\u0131\u011f\u0131 olan hastalar\u0131n beyninde oksidatif stres ve n\u00f6roinflamasyona kar\u015f\u0131 koruyucu bir etki yaratarak amiloid plaklar\u0131n ve n\u00f6rofibriler yumaklar\u0131n olu\u015fumunu azaltmaya yard\u0131mc\u0131 olabilir ve hastalar\u0131n bili\u015fsel gerilemesini geciktirebilir. <\/p>\n\n\n\n

Amiloid plaklar\u0131 sa\u011fl\u0131kl\u0131 beyinlerde de bulunabilse de, bunlar\u0131n s\u0131kl\u0131\u011f\u0131 AD beyinlerine k\u0131yasla son derece d\u00fc\u015f\u00fckt\u00fcr.<\/p>\n\n\n\n

Kannabinoidlerin AD hastalar\u0131 \u00fczerinde neden terap\u00f6tik bir etkiye sahip oldu\u011funu anlamaya y\u00f6nelik \u00e7al\u0131\u015fmalar, THC molek\u00fcl\u00fcn\u00fcn a\u015fa\u011f\u0131daki n\u00f6rotransmitterin biyoyararlan\u0131m\u0131n\u0131 art\u0131rma kapasitesine sahip oldu\u011funu ke\u015ffetti asetilkolin<\/strong> (Ach) par\u00e7alanma enzimini inhibe ederek asetilkolinesteraz<\/strong> (AChE) - Ach esasen sinir impulsunun bir sonraki n\u00f6rona aktar\u0131lmas\u0131ndan sorumludur. <\/p>\n\n\n\n

Sa\u011fl\u0131kl\u0131 bir beyinde AChE enzimi Ach'yi par\u00e7alama rol\u00fcne sahiptir, ancak Alzheimer hastal\u0131\u011f\u0131 olan bir beyinde enzim y\u00fcksek oranda bulunur ve yapmas\u0131 gerekenden \u00e7ok daha fazla Ach'yi par\u00e7alayarak zamanla beyin bili\u015f i\u015flevinin azalmas\u0131na neden olur.   <\/p>\n\n\n\n

Ara\u015ft\u0131rmac\u0131lar, kannabinoidlerin AChE enzimini inhibe edici etkisi nedeniyle yard\u0131mc\u0131 olabilece\u011fini bildirmi\u015ftir - piyasada bulunan di\u011fer ila\u00e7lardan daha iyi yan\u0131tlar g\u00f6stermi\u015ftir. <\/p>\n\n\n\n

THC ayr\u0131ca davran\u0131\u015f bozukluklar\u0131n\u0131 azaltmaya yard\u0131mc\u0131 olabilir ve a\u011f\u0131r demans hastalar\u0131n\u0131n sirkadiyen d\u00f6ng\u00fcs\u00fcn\u00fc d\u00fczenler. Hatta baz\u0131 bilim insanlar\u0131 THC ve CBD kannabinoidlerinin Alzheimer kar\u015f\u0131t\u0131 tedaviler olma potansiyeline sahip oldu\u011funu belirtmektedir.<\/p>\n\n\n\n

Clinical Pharmacology and Therapeutics dergisinde 2015 y\u0131l\u0131nda yay\u0131nlanan bir makale<\/a>ya\u015fl\u0131larda ge\u00e7 ba\u015flang\u0131\u00e7l\u0131 Alzheimer hastal\u0131\u011f\u0131 ve ilgili n\u00f6ropsikiyatrik semptomlar\u0131n tedavisinde kannabinoidlerin potansiyeline genel bir bak\u0131\u015f sunmakta ve esrar bazl\u0131 ila\u00e7lar\u0131n etkinli\u011fi, g\u00fcvenli\u011fi ve farmakokineti\u011fi konular\u0131n\u0131 da tart\u0131\u015fmaktad\u0131r.<\/p>\n\n\n\n

Alzheimer hastal\u0131\u011f\u0131 olan 72 ya\u015f\u0131nda bir erkek hastada ajitasyon ve sald\u0131rganl\u0131k gibi davran\u0131\u015f bozukluklar\u0131 vard\u0131. \u00d6nceki tedavisinde \u00f6nemli bir iyile\u015fme g\u00f6r\u00fclmemi\u015ftir. <\/p>\n\n\n\n

Hasta sentetik bir THC ilac\u0131 olan Nabilone ile tan\u0131\u015ft\u0131r\u0131ld\u0131\u011f\u0131nda, k\u0131sa s\u00fcre i\u00e7inde davran\u0131\u015f bozuklu\u011funda ve di\u011fer semptomlar\u0131nda iyile\u015fme g\u00f6sterdi, ayr\u0131ca THC bazl\u0131 ila\u00e7la tedavi s\u0131ras\u0131nda hi\u00e7bir yan etki ya\u015famad\u0131.<\/p>\n\n\n\n

\"\"<\/a>
Foto\u011fraflar Louis Reed<\/a> \u00fczerinde Unsplash<\/a><\/figcaption><\/figure>\n\n\n\n

Ya\u015f ortalamas\u0131 72 olan on be\u015f Alzheimer hastas\u0131ndan olu\u015fan bir ba\u015fka \u00e7al\u0131\u015fma grubunda, tedaviden \u00f6nce davran\u0131\u015f bozuklu\u011fu ve yemek yeme sorunlar\u0131 g\u00f6r\u00fclm\u00fc\u015ft\u00fcr. <\/p>\n\n\n\n

On be\u015f hasta alt\u0131 hafta boyunca sentetik bir THC ilac\u0131 olan ve Marinol olarak da bilinen dronabinol ile tedavi edildi. <\/p>\n\n\n\n

Bir tedavi d\u00f6neminden sonra, plasebo ile kar\u015f\u0131la\u015ft\u0131r\u0131ld\u0131\u011f\u0131nda davran\u0131\u015flarda iyile\u015fme, kilo al\u0131m\u0131 ve ajitasyonda azalma g\u00f6r\u00fclm\u00fc\u015ft\u00fcr. Yorgunluk, uyu\u015fukluk ve \u00f6fori gibi baz\u0131 yan etkiler fark edilmi\u015f ve bunlar\u0131n hepsinin dronabinol ile ili\u015fkili oldu\u011fu do\u011frulanm\u0131\u015ft\u0131r.<\/p>\n\n\n\n

Ya\u015f ortalamas\u0131 81 olan, baz\u0131lar\u0131 AD ve di\u011ferleri a\u011f\u0131r demans hastas\u0131 olan alt\u0131 hastadan olu\u015fan bir ba\u015fka grup, dronabinol ile iki haftal\u0131k bir tedaviye ba\u015flam\u0131\u015ft\u0131r. <\/p>\n\n\n\n

Sonu\u00e7lar, bu hastalar\u0131n gece motor aktivitelerinde ve daha iyi davran\u0131\u015flar\u0131nda \u00f6nemli bir iyile\u015fme oldu\u011funu g\u00f6stermi\u015ftir. Bu grupta herhangi bir yan etki g\u00f6zlenmemi\u015ftir.<\/p>\n\n\n\n

Farkl\u0131 seviyelerde bunama ya\u015fayan ve 13'\u00fc Alzheimer hastas\u0131 olan 40 hastadan olu\u015fan bir ba\u015fka \u00e7al\u0131\u015fma grubunda. <\/p>\n\n\n\n

Hepsine davran\u0131\u015f sorunlar\u0131 ve i\u015ftah bozukluklar\u0131n\u0131 tedavi etmek i\u00e7in dronabinol tedavisi uygulanm\u0131\u015ft\u0131r. <\/p>\n\n\n\n

Tedavi s\u00fcresi 17 g\u00fcnd\u00fc ve hastalar her iki a\u00e7\u0131dan da iyile\u015fme g\u00f6sterdi. Sedasyon, deliryum, idrar yolu enfeksiyonlar\u0131 ve konf\u00fczyon gibi yan etkiler bildirilmi\u015ftir ancak ara\u015ft\u0131rmac\u0131lara g\u00f6re bunlar dronabinol kullan\u0131m\u0131 ile do\u011frudan ili\u015fkili de\u011fildir.<\/p>\n\n\n\n

Demans hastalar\u0131n\u0131n tedavisinde kannabinoidlerin kullan\u0131lmas\u0131n\u0131n olumlu sonu\u00e7lar verdi\u011fini g\u00f6steren bir\u00e7ok \u00e7al\u0131\u015fma olmas\u0131na ra\u011fmen, baz\u0131 ara\u015ft\u0131rmac\u0131lar kannabinoidlerin davran\u0131\u015f bozukluklar\u0131 ve demans tedavisinde ger\u00e7ekten iyi ve g\u00fcvenli oldu\u011funu kan\u0131tlamak i\u00e7in hala yeterli kan\u0131t olmad\u0131\u011f\u0131n\u0131 iddia etmektedir.<\/p>\n\n\n\n

Her neyse, ara\u015ft\u0131rmac\u0131lar esrar bazl\u0131 ila\u00e7lar\u0131n AD'li hastalar\u0131 tedavi etmek i\u00e7in kullan\u0131ld\u0131\u011f\u0131n\u0131 giderek daha fazla bildirmektedir ve sadece bu de\u011fil, ayn\u0131 zamanda Parkinson hastal\u0131\u011f\u0131 ve otizm tedavisinde de kullan\u0131lm\u0131\u015ft\u0131r, doktorlar ve bilim adamlar\u0131 esrar bazl\u0131 ila\u00e7lar\u0131 kullanmaya ba\u015flad\u0131ktan sonra hastalar\u0131n\u0131n ya\u015fam kalitesinde iyile\u015fme oldu\u011funu bildirmi\u015flerdir. Ancak, bu bir sonraki makalenin konusu.<\/p>\n\n\n\n

___<\/p>\n\n\n\n

N\u00f6roloji alan\u0131nda m\u0131 \u00e7al\u0131\u015f\u0131yorsunuz? Mind the Graph'de n\u00f6roloji makaleniz veya sunumunuz i\u00e7in ihtiyac\u0131n\u0131z olan her \u015feyi bulabilece\u011finiz b\u00fcy\u00fck bir n\u00f6roloji ill\u00fcstrasyon kategorisi var. G\u00f6z at\u0131n Burada<\/a>.  <\/strong><\/p>\n\n\n\n

Ya da <\/strong>arad\u0131\u011f\u0131n\u0131z B\u0130YOK\u0130MYA <\/a>ve molek\u00fcler bi\u0307yoloji\u0307<\/a> Mind the Graph'de de bulabilece\u011finiz ill\u00fcstrasyonlar. <\/p>\n\n\n\n

Ve ba\u015fka bir \u015feye ihtiyac\u0131n\u0131z olursa size yard\u0131mc\u0131 olmak i\u00e7in buraday\u0131z, sadece hesab\u0131n\u0131za giri\u015f yap\u0131n<\/a> ve bize bir mesaj g\u00f6nderin BIR SIMGE TALEP EDIN<\/strong>. <\/p>\n\n\n\n

Referanslar<\/strong><\/p>\n\n\n\n

AHMED, A. I. A. ve di\u011ferleri. Ge\u00e7 ba\u015flang\u0131\u00e7l\u0131 Alzheimer hastal\u0131\u011f\u0131nda kannabinoidler. Klinik Farmakoloji ve Terap\u00f6tikler<\/strong>, v. 97, n. 6, p. 597-606, 2015.<\/p>\n\n\n\n

AHMED, A. I. A. ve di\u011ferleri. Ge\u00e7 ba\u015flang\u0131\u00e7l\u0131 Alzheimer hastal\u0131\u011f\u0131nda kannabinoidler. Klinik Farmakoloji ve Terap\u00f6tikler<\/strong>, v. 97, n. 6, p. 597-606, 2015.<\/p>\n\n\n\n

BALASH, Y. ve di\u011ferleri. Parkinson Hastal\u0131\u011f\u0131nda T\u0131bbi Kenevir: Ger\u00e7ek Ya\u015famda Hastalar\u0131n Deneyimleri. Klinik N\u00f6rofarmakoloji<\/strong>, v. 40, n. 6, p. 268-272, dez. 2017.<\/p>\n\n\n\n

BENITO, C. ve di\u011ferleri. Endokannabinoid Sistem ve Alzheimer Hastal\u0131\u011f\u0131. Molek\u00fcler N\u00f6robiyoloji<\/strong>, v. 36, n. 1, p. 75-81, 1 \u00f6nce. 2007.<\/p>\n\n\n\n

DE FARIA, S. M. ve di\u011ferleri. Akut kannabidiol uygulamas\u0131n\u0131n Parkinson hastal\u0131\u011f\u0131 olan hastalarda Sim\u00fcle Topluluk \u00d6n\u00fcnde Konu\u015fma Testinin neden oldu\u011fu anksiyete ve titreme \u00fczerindeki etkileri. Psikofarmakoloji Dergisi<\/strong>, v. 34, n. 2, p. 189-196, 1 fev. 2020.<\/p>\n\n\n\n

FALCO, A. D. ve di\u011ferleri DOEN\u00c7A DE ALZHEIMER: HIP\u00d3TESES ETIOL\u00d3GICAS E PERSPECTIVAS DE TRATAMENTO. Qu\u00edmica Nova<\/strong>, v. 39, n. 1, p. 63-80, jan. 2016.<\/p>\n\n\n\n

LEEHEY, M. A. ve di\u011ferleri. Parkinson Hastal\u0131\u011f\u0131nda Kannabidiol\u00fcn G\u00fcvenli\u011fi ve Tolere Edilebilirli\u011fi: A\u00e7\u0131k Etiketli, Doz Y\u00fckseltme \u00c7al\u0131\u015fmas\u0131. Kenevir ve Kannabinoid Ara\u015ft\u0131rmalar\u0131<\/strong>19 Mart. 2020.<\/p>\n\n\n\n

POLEG, S. ve ark. Otizm spektrum bozuklu\u011funun tedavisi i\u00e7in \u00f6nerilen bir aday olarak kannabidiol. N\u00f6ro-Psikofarmakoloji ve Biyolojik Psikiyatride \u0130lerleme<\/strong>, v. 89, p. 90-96, 8 mar. 2019.YOO, K.-Y.; PARK, S.-Y. Potansiyel Anti-Alzheimer Hastal\u0131\u011f\u0131 Terap\u00f6tikleri Olarak Terpenoidler. Molek\u00fcller<\/strong>, v. 17, n. 3, p. 3524-3538, mar. 2012.<\/p>","protected":false},"excerpt":{"rendered":"

Alzheimer hastal\u0131\u011f\u0131 (AH), g\u00fcn\u00fcm\u00fczde te\u015fhis edilen demans vakalar\u0131n\u0131n 50%'sinden fazlas\u0131ndan sorumlu n\u00f6rodejeneratif bir hastal\u0131kt\u0131r ve ya\u015flanma ile do\u011frudan ili\u015fkilidir. G\u00fcn\u00fcm\u00fczde 85 ya\u015f\u0131n \u00fczerindeki insanlar\u0131n 40%'sinde bir miktar demans g\u00f6r\u00fclmektedir. Daha \u00f6nce, AD semptomlar\u0131n\u0131n sadece k\u0131sa s\u00fcreli haf\u0131zay\u0131 etkileyen bir bili\u015fsel i\u015flev d\u00fc\u015f\u00fc\u015f\u00fc ile ilgili oldu\u011fu d\u00fc\u015f\u00fcn\u00fcl\u00fcrken, [...]<\/p>","protected":false},"author":4,"featured_media":12193,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[959],"tags":[213,819,554],"yoast_head":"\nWhat is Out There About Cannabis and Alzheimer\u2019s Disease - MTG<\/title>\n<meta name=\"description\" content=\"Do you know Cannabis and Alzheimer's Disease can be related? Yes, read this blog to know what is out there about cannabis and Alzheimer\u2019s disease.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mindthegraph.com\/blog\/tr\/\u043a\u0430\u043d\u043d\u0430\u0431\u0438\u0441-\u0438-\u0431\u043e\u043b\u0435\u0437\u043d\u044c-\u0430\u043b\u044c\u0446\u0433\u0435\u0439\u043c\u0435\u0440\u0430\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"What is Out There About Cannabis and Alzheimer\u2019s Disease - MTG\" \/>\n<meta property=\"og:description\" content=\"Do you know Cannabis and Alzheimer's Disease can be related? Yes, read this blog to know what is out there about cannabis and Alzheimer\u2019s disease.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/mindthegraph.com\/blog\/tr\/\u043a\u0430\u043d\u043d\u0430\u0431\u0438\u0441-\u0438-\u0431\u043e\u043b\u0435\u0437\u043d\u044c-\u0430\u043b\u044c\u0446\u0433\u0435\u0439\u043c\u0435\u0440\u0430\/\" \/>\n<meta property=\"og:site_name\" content=\"Mind the Graph Blog\" \/>\n<meta property=\"article:published_time\" content=\"2021-01-27T12:46:16+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-01-05T17:40:18+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2021\/01\/what-is-out-there-about-cannabis-and-alzheimers-disease.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1123\" \/>\n\t<meta property=\"og:image:height\" content=\"612\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Fabricio Pamplona\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Fabricio Pamplona\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"6 minutes\" \/>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"What is Out There About Cannabis and Alzheimer\u2019s Disease - MTG","description":"Do you know Cannabis and Alzheimer's Disease can be related? Yes, read this blog to know what is out there about cannabis and Alzheimer\u2019s disease.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/mindthegraph.com\/blog\/tr\/\u043a\u0430\u043d\u043d\u0430\u0431\u0438\u0441-\u0438-\u0431\u043e\u043b\u0435\u0437\u043d\u044c-\u0430\u043b\u044c\u0446\u0433\u0435\u0439\u043c\u0435\u0440\u0430\/","og_locale":"tr_TR","og_type":"article","og_title":"What is Out There About Cannabis and Alzheimer\u2019s Disease - MTG","og_description":"Do you know Cannabis and Alzheimer's Disease can be related? Yes, read this blog to know what is out there about cannabis and Alzheimer\u2019s disease.","og_url":"https:\/\/mindthegraph.com\/blog\/tr\/\u043a\u0430\u043d\u043d\u0430\u0431\u0438\u0441-\u0438-\u0431\u043e\u043b\u0435\u0437\u043d\u044c-\u0430\u043b\u044c\u0446\u0433\u0435\u0439\u043c\u0435\u0440\u0430\/","og_site_name":"Mind the Graph Blog","article_published_time":"2021-01-27T12:46:16+00:00","article_modified_time":"2023-01-05T17:40:18+00:00","og_image":[{"width":1123,"height":612,"url":"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2021\/01\/what-is-out-there-about-cannabis-and-alzheimers-disease.png","type":"image\/png"}],"author":"Fabricio Pamplona","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Fabricio Pamplona","Est. reading time":"6 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/mindthegraph.com\/blog\/ru\/%d0%ba%d0%b0%d0%bd%d0%bd%d0%b0%d0%b1%d0%b8%d1%81-%d0%b8-%d0%b1%d0%be%d0%bb%d0%b5%d0%b7%d0%bd%d1%8c-%d0%b0%d0%bb%d1%8c%d1%86%d0%b3%d0%b5%d0%b9%d0%bc%d0%b5%d1%80%d0%b0\/","url":"https:\/\/mindthegraph.com\/blog\/ru\/%d0%ba%d0%b0%d0%bd%d0%bd%d0%b0%d0%b1%d0%b8%d1%81-%d0%b8-%d0%b1%d0%be%d0%bb%d0%b5%d0%b7%d0%bd%d1%8c-%d0%b0%d0%bb%d1%8c%d1%86%d0%b3%d0%b5%d0%b9%d0%bc%d0%b5%d1%80%d0%b0\/","name":"What is Out There About Cannabis and Alzheimer\u2019s Disease - MTG","isPartOf":{"@id":"https:\/\/mindthegraph.com\/blog\/#website"},"datePublished":"2021-01-27T12:46:16+00:00","dateModified":"2023-01-05T17:40:18+00:00","author":{"@id":"https:\/\/mindthegraph.com\/blog\/#\/schema\/person\/c8eaee6d8007ac319523c3ddc98cedd3"},"description":"Do you know Cannabis and Alzheimer's Disease can be related? Yes, read this blog to know what is out there about cannabis and Alzheimer\u2019s disease.","breadcrumb":{"@id":"https:\/\/mindthegraph.com\/blog\/ru\/%d0%ba%d0%b0%d0%bd%d0%bd%d0%b0%d0%b1%d0%b8%d1%81-%d0%b8-%d0%b1%d0%be%d0%bb%d0%b5%d0%b7%d0%bd%d1%8c-%d0%b0%d0%bb%d1%8c%d1%86%d0%b3%d0%b5%d0%b9%d0%bc%d0%b5%d1%80%d0%b0\/#breadcrumb"},"inLanguage":"tr-TR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/mindthegraph.com\/blog\/ru\/%d0%ba%d0%b0%d0%bd%d0%bd%d0%b0%d0%b1%d0%b8%d1%81-%d0%b8-%d0%b1%d0%be%d0%bb%d0%b5%d0%b7%d0%bd%d1%8c-%d0%b0%d0%bb%d1%8c%d1%86%d0%b3%d0%b5%d0%b9%d0%bc%d0%b5%d1%80%d0%b0\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/mindthegraph.com\/blog\/ru\/%d0%ba%d0%b0%d0%bd%d0%bd%d0%b0%d0%b1%d0%b8%d1%81-%d0%b8-%d0%b1%d0%be%d0%bb%d0%b5%d0%b7%d0%bd%d1%8c-%d0%b0%d0%bb%d1%8c%d1%86%d0%b3%d0%b5%d0%b9%d0%bc%d0%b5%d1%80%d0%b0\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/mindthegraph.com\/blog\/"},{"@type":"ListItem","position":2,"name":"What is Out There About Cannabis and Alzheimer\u2019s Disease"}]},{"@type":"WebSite","@id":"https:\/\/mindthegraph.com\/blog\/#website","url":"https:\/\/mindthegraph.com\/blog\/","name":"Mind the Graph Blog","description":"Your science can be beautiful!","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/mindthegraph.com\/blog\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"tr-TR"},{"@type":"Person","@id":"https:\/\/mindthegraph.com\/blog\/#\/schema\/person\/c8eaee6d8007ac319523c3ddc98cedd3","name":"Fabricio Pamplona","image":{"@type":"ImageObject","inLanguage":"tr-TR","@id":"https:\/\/mindthegraph.com\/blog\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/da6985d9f20ecb24f3238df103a638ac?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/da6985d9f20ecb24f3238df103a638ac?s=96&d=mm&r=g","caption":"Fabricio Pamplona"},"description":"Fabricio Pamplona is the founder of Mind the Graph - a tool used by over 400K users in 60 countries. He has a Ph.D. and solid scientific background in Psychopharmacology and experience as a Guest Researcher at the Max Planck Institute of Psychiatry (Germany) and Researcher in D'Or Institute for Research and Education (IDOR, Brazil). Fabricio holds over 2500 citations in Google Scholar. He has 10 years of experience in small innovative businesses, with relevant experience in product design and innovation management. Connect with him on LinkedIn - Fabricio Pamplona.","sameAs":["http:\/\/mindthegraph.com","https:\/\/www.linkedin.com\/in\/fabriciopamplona"],"url":"https:\/\/mindthegraph.com\/blog\/tr\/author\/fabricio\/"}]}},"_links":{"self":[{"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/posts\/12192"}],"collection":[{"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/comments?post=12192"}],"version-history":[{"count":5,"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/posts\/12192\/revisions"}],"predecessor-version":[{"id":26035,"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/posts\/12192\/revisions\/26035"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/media\/12193"}],"wp:attachment":[{"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/media?parent=12192"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/categories?post=12192"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/tags?post=12192"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}