{"id":12130,"date":"2021-01-13T09:30:00","date_gmt":"2021-01-13T11:30:00","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=12130"},"modified":"2022-10-18T08:09:26","modified_gmt":"2022-10-18T11:09:26","slug":"pyscratch-spatial-and-temporal-information-from-scratch-assays","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/tr\/pyscratch-spatial-and-temporal-information-from-scratch-assays\/","title":{"rendered":"PyScratch: Scratch Deneylerinden Mekansal ve Zamansal Bilgileri \u0130\u015flemek i\u00e7in Yeni Bir Ara\u00e7"},"content":{"rendered":"

PyScratch, g\u00f6\u00e7 veri analizleri i\u00e7in Python'da uygulanan yeni bir a\u00e7\u0131k kaynakl\u0131 yaz\u0131l\u0131md\u0131r ve kullan\u0131c\u0131 dostu bir aray\u00fcze sahip olup programlama becerisi az olan veya hi\u00e7 olmayan bilim insanlar\u0131n\u0131n kullanmas\u0131na olanak tan\u0131r. <\/p>\n\n\n\n

Yaz\u0131l\u0131m, 2017 y\u0131l\u0131nda Campinas \u00dcniversitesi'ndeki NanoCell Interactions laboratuvar\u0131nda \u00fc\u00e7 Brezilyal\u0131 bilim insan\u0131n\u0131n ortakl\u0131\u011f\u0131nda tasarland\u0131. <\/p>\n\n\n\n

Bu bilim insanlar\u0131n\u0131n ihtiya\u00e7lar\u0131ndan do\u011fmu\u015ftur ve bug\u00fcn yaz\u0131l\u0131m\u0131n amac\u0131 ara\u015ft\u0131rmac\u0131lar\u0131n g\u00fcnl\u00fck uygulamalar\u0131n\u0131 kolayla\u015ft\u0131rmak, manuel analizi d\u0131\u015flamak, tekrarlanabilirli\u011fi art\u0131rmak ve insan hatalar\u0131n\u0131 en aza indirmektir.<\/p>\n\n\n\n

\"\"<\/a><\/figure><\/div>\n\n\n\n

G\u00f6r\u00fcnt\u00fc analizi, bilim insanlar\u0131 taraf\u0131ndan sonu\u00e7lar\u0131 analiz etmek i\u00e7in farkl\u0131 metodolojilerde kullan\u0131lan en \u00f6nemli yollardan biri olmu\u015ftur. <\/p>\n\n\n\n

Ge\u00e7ti\u011fimiz y\u0131llarda sadece otomatik mikroskoplar\u0131n kullan\u0131m\u0131 artmakla kalmam\u0131\u015f, ayn\u0131 zamanda elde edilen verilerin karma\u015f\u0131kl\u0131\u011f\u0131 da artm\u0131\u015ft\u0131r. <\/p>\n\n\n\n

Bir bilim insan\u0131n\u0131n i\u015finin bir k\u0131sm\u0131, verileri analiz etmenin ve i\u015flemenin yan\u0131 s\u0131ra yeni bir bilgi t\u00fcr\u00fcyle nas\u0131l ba\u015fa \u00e7\u0131k\u0131laca\u011f\u0131n\u0131 ke\u015ffetmektir. <\/p>\n\n\n\n

Bunun ger\u00e7ekle\u015fmesi i\u00e7in bilim insanlar\u0131n\u0131n t\u00fcm verileri do\u011fru bir \u015fekilde \u00e7\u0131karmak ve yorumlamak i\u00e7in iyi ve \u00f6zel ara\u00e7lara ihtiyac\u0131 vard\u0131r.<\/p>\n\n\n\n

PyScratch ilk olarak biyolog bir ara\u015ft\u0131rmac\u0131 olan Fernanda Garcia-Fossa'n\u0131n g\u00f6\u00e7 deneylerinden elde etti\u011fi b\u00fcy\u00fck miktarda veriyi analiz etmesine yard\u0131mc\u0131 olmak i\u00e7in olu\u015fturuldu. <\/p>\n\n\n\n

\"Kanser h\u00fccrelerine \u00e7izik att\u0131m ve her 15 dakikada bir foto\u011fraf \u00e7ekerek 48 saat boyunca ekipman\u0131n i\u00e7inde ink\u00fcbe ettim ve sadece bir deneyin sonunda bak\u0131p analiz edebilece\u011fim yakla\u015f\u0131k bin foto\u011fraf\u0131m oldu! <\/p>\n\n\n\n

Bunu elle yapmak imkans\u0131zd\u0131\" diyor Garcia-Fossa. Garcia-Fossa bu sorunu \u00e7\u00f6zmek i\u00e7in orta\u011f\u0131 fizik\u00e7i Vladimir Gaal'in yard\u0131m\u0131na ba\u015fvurdu, o s\u0131rada Gaal Python \u00f6\u011freniyordu ve bu da bilgilerini uygulamaya koymak i\u00e7in harika bir f\u0131rsatt\u0131.<\/p>\n\n\n\n

B\u00f6ylece, her ikisi de \u00e7izilen alanlar\u0131 tan\u0131yan ve bir csv dosyas\u0131na aktaran bir Python rutini arac\u0131l\u0131\u011f\u0131yla \u00e7\u00f6z\u00fcmde \u00e7al\u0131\u015ft\u0131. <\/p>\n\n\n\n

\"Zamanla, kullan\u0131m\u0131 daha da kolayla\u015ft\u0131ran bir kullan\u0131c\u0131 aray\u00fcz\u00fc geli\u015ftirme ihtiyac\u0131 hissettik, bu \u015fekilde yaz\u0131l\u0131m\u0131 ihtiya\u00e7 duyan herhangi bir ara\u015ft\u0131rmac\u0131 i\u00e7in de yay\u0131nlayabilirdik\" diyen Garcia-Fossa'n\u0131n yaz\u0131l\u0131mla ilgili makalesine buradan g\u00f6z atabilirsiniz buraya t\u0131klayarak<\/a>.<\/p>\n\n\n\n

Garcia-Fossa ayr\u0131ca g\u00f6r\u00fcnt\u00fclerden g\u00f6\u00e7 alan\u0131n\u0131 tan\u0131mak ve tan\u0131mlamak i\u00e7in biraz zaman harcad\u0131klar\u0131n\u0131, \u00e7\u00fcnk\u00fc resimlerin \u0131\u015f\u0131k, odak ve kontrast nedeniyle birbirinden \u00e7ok farkl\u0131 olabilece\u011fini ve bug\u00fcn kullan\u0131lan versiyonun zaten olduk\u00e7a iyi analiz edebildi\u011fini s\u00f6yl\u00fcyor. <\/p>\n\n\n\n

Bununla birlikte, yay\u0131nlanan makale kullan\u0131c\u0131lar\u0131n talebi nedeniyle baz\u0131 iyile\u015ftirme ihtiya\u00e7lar\u0131n\u0131 g\u00fcndeme getirdi\u011finden, yeni ve daha iyi s\u00fcr\u00fcmleri piyasaya s\u00fcrmek i\u00e7in yaz\u0131l\u0131m \u00fczerinde \u00e7al\u0131\u015fmaya devam ediyorlar.<\/p>\n\n\n\n

Yaz\u0131l\u0131m performans\u0131n\u0131 do\u011frulamak i\u00e7in kullan\u0131lan g\u00f6\u00e7 deneyi veya \u00e7izik deneyi veya yara iyile\u015fmesi, fizyolojik ve patolojik h\u00fccresel olaylar\u0131n alt\u0131nda yatan mekanizmay\u0131 analiz etmeyi m\u00fcmk\u00fcn k\u0131ld\u0131\u011f\u0131 i\u00e7in biyolojide yayg\u0131n olarak kullan\u0131lan bir deneydir. <\/p>\n\n\n\n

Yara iyile\u015fmesini incelemek, anjiyogenez ve t\u00fcm\u00f6r geli\u015fiminin yan\u0131 s\u0131ra geli\u015fimi ve doku modellemesini anlamak i\u00e7in \u00f6nemli bir yoldur. <\/p>\n\n\n\n

Test iki boyutlu olarak ger\u00e7ekle\u015ftirildi\u011finde, h\u00fccrelerin tan\u0131mlanan alan\u0131 kaplayan yaraya ne kadar h\u0131zl\u0131 tepki verdi\u011fini \u00f6l\u00e7mek m\u00fcmk\u00fcnd\u00fcr.<\/p>\n\n\n\n

Ba\u015fka bir deyi\u015fle, deney temel olarak, bir plak i\u00e7indeki konfluens h\u00fccrelerin tek tabakas\u0131nda bir bo\u015fluk olu\u015fturmakt\u0131r. <\/p>\n\n\n\n

Zamanla, bo\u015flu\u011fu doldurmak i\u00e7in h\u00fccreler g\u00f6\u00e7 etmeye ba\u015flar ve h\u00fccrelerin g\u00f6\u00e7 h\u0131z\u0131 \u00f6l\u00e7\u00fclebilir. <\/p>\n\n\n\n

Ard\u0131ndan, h\u00fccre g\u00f6\u00e7 h\u0131z\u0131n\u0131 \u00f6l\u00e7mek i\u00e7in bir s\u00fcr\u00fc g\u00f6r\u00fcnt\u00fc elde etmeleri gerekiyor ki bu da manuel \u00f6l\u00e7\u00fcm gerektirdi\u011fi i\u00e7in analizin sorunlu bir ad\u0131m\u0131. <\/p>\n\n\n\n

Neyse ki bug\u00fcn, analiz hatt\u0131m\u0131z\u0131 iyile\u015ftirmek ve y\u00fckseltmek i\u00e7in elimizde \u00e7ok say\u0131da teknoloji var ve bu da bilim insanlar\u0131n\u0131n bir sonu\u00e7 elde etmek i\u00e7in daha iyi ve daha ki\u015fiselle\u015ftirilmi\u015f yollar benimsemesine olanak tan\u0131yor. <\/p>\n\n\n\n

Garcia-Fossa ve Gaal'\u0131n yapt\u0131\u011f\u0131 gibi.<\/p>\n\n\n\n

G\u00fcn\u00fcm\u00fczde yara b\u00f6lgesini i\u015flemek i\u00e7in ba\u015fka ticari ve ticari olmayan ara\u00e7lar bulmak m\u00fcmk\u00fcnd\u00fcr. <\/p>\n\n\n\n

Ancak PyScratch kadar basit de\u011fildirler ve kullan\u0131c\u0131dan belirli bir d\u00fczeyde programlama gerektirir ve ayr\u0131ca kullan\u0131c\u0131n\u0131n tam zamanl\u0131 dikkatini gerektirir, bu da analizi insan hatalar\u0131na kar\u015f\u0131 daha duyarl\u0131 hale getirir, ayr\u0131ca ara\u015ft\u0131rmac\u0131n\u0131n t\u00fcm resimleri ve verileri analiz etmek i\u00e7in harcad\u0131\u011f\u0131 zaman.<\/p>\n\n\n\n

Makalede yazarlar yaz\u0131l\u0131m\u0131n nas\u0131l \u00e7al\u0131\u015ft\u0131\u011f\u0131n\u0131 a\u00e7\u0131kl\u0131yor. Deneyde yap\u0131lan t\u00fcm resimlerden kullan\u0131c\u0131, tablo halindeki verileri d\u00fcz metin olarak saklayan bir \u00e7\u0131kt\u0131 olan virg\u00fclle ayr\u0131lm\u0131\u015f de\u011ferler (.cvs) dosyas\u0131 al\u0131yor. <\/p>\n\n\n\n

Kullan\u0131c\u0131 daha sonra verileri normal rutininde i\u015fleyebiliyor. Garcia-Fossa, program\u0131n y\u00fcksek lisans tezi i\u00e7in \u00e7ok \u00f6nemli oldu\u011funu s\u00f6yl\u00fcyor: \"Yaz\u0131l\u0131m, girdi verilerini h\u00fccre g\u00f6\u00e7 h\u0131z\u0131 gibi biyolojik a\u00e7\u0131dan anlaml\u0131 de\u011ferlere d\u00f6n\u00fc\u015ft\u00fcr\u00fcyor. <\/p>\n\n\n\n

PyScratch sayesinde nanopartik\u00fcl\u00fcm\u00fcn prostat kanseri h\u00fccreleri \u00fczerindeki etkisini daha iyi analiz edebildim ve h\u00fccre g\u00f6\u00e7 h\u0131z\u0131n\u0131 ve iyi kapanma i\u00e7in tam zaman\u0131 \u00f6l\u00e7ebildim.\"<\/p>\n\n\n\n

\"\"<\/a><\/figure><\/div>\n\n\n\n

Ara\u015ft\u0131rman\u0131z i\u00e7in PyScratch'i denemek istiyorsan\u0131z, yaz\u0131l\u0131m \u00fccretsiz olarak kullan\u0131labilir ve bilim camias\u0131ndan herkesin onu kullanmas\u0131na izin verilerek Garcia-Fossa ve Gaal'in program\u0131 geli\u015ftirmesine ve iyile\u015ftirmesine yard\u0131mc\u0131 olunur.<\/p>\n\n\n\n

 ____<\/p>\n\n\n\n

Mind the Graph deneyiminiz \u015fu ana kadar nas\u0131l gidiyor? Platformumuzu sizin i\u00e7in ve Mind the Graph incelemesi g\u00f6nderen di\u011fer bir\u00e7ok bilim insan\u0131 i\u00e7in geli\u015ftirmemize yard\u0131mc\u0131 olun. Bize deneyiminizi anlat\u0131n, sadece t\u0131klay\u0131n Burada<\/a>. <\/p>","protected":false},"excerpt":{"rendered":"

PyScratch, g\u00f6\u00e7 verisi analizleri i\u00e7in Python'da uygulanan yeni bir a\u00e7\u0131k kaynakl\u0131 yaz\u0131l\u0131md\u0131r ve programlama becerisi az olan veya hi\u00e7 olmayan bilim insanlar\u0131n\u0131n kullanmas\u0131na olanak tan\u0131yan kullan\u0131c\u0131 dostu bir aray\u00fcze sahiptir. Yaz\u0131l\u0131m, 2017 y\u0131l\u0131nda Campinas \u00dcniversitesi NanoCell Interactions laboratuvar\u0131nda \u00fc\u00e7 Brezilyal\u0131 bilim insan\u0131 aras\u0131ndaki bir ortakl\u0131kla tasarlanm\u0131\u015ft\u0131r. Bu [...]<\/p>","protected":false},"author":4,"featured_media":12133,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[959,28],"tags":[817,554,964],"yoast_head":"\nA new tool for processing spatial and temporal information<\/title>\n<meta name=\"description\" content=\"Read this blog to know what PyScratch is and how that new tool processes spatial and temporal information from scratch assays.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mindthegraph.com\/blog\/tr\/saggi-pyscratch-spatial-and-temporal-information-from-scratch\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"A new tool for processing spatial and temporal information\" \/>\n<meta property=\"og:description\" content=\"Read this blog to 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He has a Ph.D. and solid scientific background in Psychopharmacology and experience as a Guest Researcher at the Max Planck Institute of Psychiatry (Germany) and Researcher in D'Or Institute for Research and Education (IDOR, Brazil). Fabricio holds over 2500 citations in Google Scholar. He has 10 years of experience in small innovative businesses, with relevant experience in product design and innovation management. Connect with him on LinkedIn - Fabricio Pamplona.","sameAs":["http:\/\/mindthegraph.com","https:\/\/www.linkedin.com\/in\/fabriciopamplona"],"url":"https:\/\/mindthegraph.com\/blog\/tr\/author\/fabricio\/"}]}},"_links":{"self":[{"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/posts\/12130"}],"collection":[{"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/comments?post=12130"}],"version-history":[{"count":1,"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/posts\/12130\/revisions"}],"predecessor-version":[{"id":12134,"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/posts\/12130\/revisions\/12134"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/media\/12133"}],"wp:attachment":[{"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/media?parent=12130"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/categories?post=12130"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/tags?post=12130"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}