{"id":10972,"date":"2020-03-20T08:22:00","date_gmt":"2020-03-20T11:22:00","guid":{"rendered":"https:\/\/blog.mindthegraph.com\/?p=10972"},"modified":"2022-10-18T08:09:52","modified_gmt":"2022-10-18T11:09:52","slug":"coronavirus-covid-19-is-hydroxychloroquine-the-new-hope-apparently-yes","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/tr\/coronavirus-covid-19-is-hydroxychloroquine-the-new-hope-apparently-yes\/","title":{"rendered":"Koronavir\u00fcs (Covid-19): hidroksiklorokin yeni umut mu? G\u00f6r\u00fcn\u00fc\u015fe g\u00f6re, evet."},"content":{"rendered":"<p>Bir in vitro ara\u015ft\u0131rmay\u0131 ve k\u00fc\u00e7\u00fck \u00f6l\u00e7ekli bir klinik \u00e7al\u0131\u015fmay\u0131 \u00f6zetleyen iki yeni makale, Donald Trump'\u0131n FDA'n\u0131n hidroksiklorokin i\u00e7in yeni bir ila\u00e7 klinik endikasyonunu y\u00fcr\u00fcrl\u00fc\u011fe koymas\u0131 i\u00e7in yeterli oldu: Koronavir\u00fcs (Covid-19) ile etkilenen hastalar\u0131n semptomlar\u0131n\u0131 iyile\u015ftirmek.<\/p>\n<p>Bu muhtemelen modern tarihteki en h\u0131zl\u0131 ila\u00e7 onay s\u00fcrecidir ve Ba\u015fkan g\u00f6r\u00fcn\u00fc\u015fe g\u00f6re hakl\u0131d\u0131r. Bilimi pek sevmeyen bir d\u00fcnya lideri i\u00e7in \u015fa\u015f\u0131rt\u0131c\u0131.<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"aligncenter size-full wp-image-10976\" src=\"https:\/\/blog.mindthegraph.com\/wp-content\/uploads\/2020\/03\/image-192.png\" alt=\"\" width=\"607\" height=\"480\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2020\/03\/image-192.png 607w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2020\/03\/image-192-300x237.png 300w\" sizes=\"(max-width: 607px) 100vw, 607px\" \/><\/p>\n<p>Hidroksiklorokinin vir\u00fcs \u00fczerindeki etkisine dair ilk kan\u0131t <a href=\"https:\/\/www.nature.com\/articles\/s41421-020-0156-0\">Bu makale d\u00fcn Cell Discovery'de yay\u0131nland\u0131<\/a>T\u00fcm s\u0131n\u0131rlamalarla birlikte sadece in vitro bir \u00e7al\u0131\u015fma, ancak ilac\u0131n vir\u00fcs\u00fc \u00f6ld\u00fcrme potansiyelini a\u00e7\u0131k\u00e7a g\u00f6steriyor. Makaleyi sunduklar\u0131nda \u00c7in'de 2946 \u00f6l\u00fcm dahil olmak \u00fczere 80.000 vaka ve 72 ba\u015fka \u00fclkede 10.566'dan fazla vaka teyit edilmi\u015fti. O d\u00f6nemde en b\u00fcy\u00fck umut remdesivir adl\u0131 bir ilaca ba\u011flanm\u0131\u015ft\u0131.<\/p>\n<figure id=\"attachment_10973\" aria-describedby=\"caption-attachment-10973\" style=\"width: 584px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" loading=\"lazy\" class=\"size-full wp-image-10973\" src=\"https:\/\/blog.mindthegraph.com\/wp-content\/uploads\/2020\/03\/image-191.png\" alt=\"hidroklorokinin koronavir\u00fcs (Covid-19) \u00fczerindeki in vitro etkileri\" width=\"584\" height=\"401\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2020\/03\/image-191.png 584w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2020\/03\/image-191-300x206.png 300w\" sizes=\"(max-width: 584px) 100vw, 584px\" \/><figcaption id=\"caption-attachment-10973\" class=\"wp-caption-text\">Hidroklorokinin koronavir\u00fcs (Covid-19) \u00fczerindeki in vitro etkileri. Sa\u011fdaki s\u00fctun, klorokin veya soldaki kontrol grubunun aksine etkili ilac\u0131n etkilerini g\u00f6stermektedir. \u0130lac\u0131n, h\u00fccrelerin vir\u00fcsleri d\u0131\u015far\u0131 atma kabiliyetini geli\u015ftirdi\u011fini g\u00f6steriyor... Bu, istenmeyen bir kom\u015fuyu evinizden kovmaya yard\u0131mc\u0131 olmak gibi bir \u015fey. \u0130\u015fe yar\u0131yor! \ud83d\ude42&nbsp;<\/figcaption><\/figure>\n<p>Ancak en b\u00fcy\u00fck haber \u00f6nceki g\u00fcn yay\u0131nlanan k\u00fc\u00e7\u00fck \u00f6l\u00e7ekli bir klinik \u00e7al\u0131\u015fmadan geldi. Ba\u015fl\u0131k <a href=\"https:\/\/www.mediterranee-infection.com\/wp-content\/uploads\/2020\/03\/Hydroxychloroquine_final_DOI_IJAA.pdf\">COVID-19 tedavisi olarak hidroksiklorokin ve azitromisin: a\u00e7\u0131k etiketli randomize olmayan bir klinik \u00e7al\u0131\u015fman\u0131n sonu\u00e7lar\u0131 ve \"in press\" versiyonundan indirilebilir<\/a><\/p>\n<p>Sadece 20 hastayla yap\u0131lan bir \u00e7al\u0131\u015fmada, yazarlar hidroksiklorokinin koronavir\u00fcs Covid-19 enfeksiyonuna kar\u015f\u0131 etkili oldu\u011funu g\u00f6stermi\u015ftir. Asl\u0131nda, 6 g\u00fcnl\u00fck d\u00f6nemde enfekte bireylerin 75%'sini azaltm\u0131\u015ft\u0131r ki bu harika bir \u015feydir. Bundan daha da iyisi, azitromisin ile kombinasyon tedavi etkinli\u011fini 95%'ye y\u00fckseltmi\u015ftir.<\/p>\n<figure id=\"attachment_10975\" aria-describedby=\"caption-attachment-10975\" style=\"width: 668px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" loading=\"lazy\" class=\"wp-image-10975\" src=\"https:\/\/blog.mindthegraph.com\/wp-content\/uploads\/2020\/03\/Hydroxychloroquine_final_DOI_IJAA-24-1024x546-1.jpg\" alt=\"Hidrohiklorokin ve azitromisin kombine tedavisi insan hastalarda koronavir\u00fcs (Covid-19) enfeksiyonlar\u0131na kar\u015f\u0131 etkilidir\" width=\"668\" height=\"356\"><figcaption id=\"caption-attachment-10975\" class=\"wp-caption-text\">Hidrohiklorokin ve azitromisin kombine tedavisi, insan hastalarda koronavir\u00fcs (Covid-19) enfeksiyonlar\u0131na kar\u015f\u0131 etkilidir. Bu d\u00fc\u015f\u00fc\u015f dramatiktir ve etkilenen hastalara yeni bir umut getirmektedir.<\/figcaption><\/figure>\n<p>Tedavi semptomlar\u0131 iyile\u015ftirirken, hastalardaki viral y\u00fck\u00fc de azaltt\u0131. \u0130la\u00e7 daha \u00f6nce s\u0131tma i\u00e7in onaylanm\u0131\u015ft\u0131, bu da g\u00fcvenli oldu\u011fu anlam\u0131na geliyor. \"Karde\u015f\" ila\u00e7 klorokin daha az etkiliydi. Bizim i\u00e7in iyi, \u00e7\u00fcnk\u00fc o daha toksik.<\/p>\n<p>\u00c7al\u0131\u015fma randomize de\u011fildir ve k\u00fc\u00e7\u00fck \u00f6l\u00e7eklidir, ancak salg\u0131n \u00c7in'de ba\u015flam\u0131\u015f olsa da, \u00e7\u00f6z\u00fcm k\u00fcresel bir topluluk \u00e7abas\u0131ndan geliyor gibi g\u00f6r\u00fcnmektedir. \u0130n vitro makale asl\u0131nda \u00c7in'den, klinik makale ise Avrupa'dan, daha do\u011frusu Fransa'dan. \u0130lgin\u00e7 bir \u015fekilde, hidroksiklorokin i\u00e7in orijinal ila\u00e7 ruhsatlar\u0131 Frans\u0131z ila\u00e7 \u015firketi Sanofi'ye aittir ve son klinik \u00e7al\u0131\u015fma Marsilya'da yap\u0131lm\u0131\u015ft\u0131r. Ale le bleu!<\/p>\n<p style=\"text-align: center;\"><a href=\"https:\/\/www.medscape.com\/viewarticle\/927033#vp_1\">Daha ayr\u0131nt\u0131l\u0131 bilgi edinmek isteyenler i\u00e7in Medscape'in bu konuda m\u00fckemmel bir makalesi var.<\/a><\/p>\n<p>L\u00fctfen bu \u00e7al\u0131\u015fmay\u0131 Gautret ve di\u011ferleri (2020) COVID-19 tedavisi olarak hidroksiklorokin ve azitromisin: a\u00e7\u0131k etiketli randomize olmayan bir klinik \u00e7al\u0131\u015fman\u0131n sonu\u00e7lar\u0131 olarak al\u0131nt\u0131lay\u0131n. International Journal of Antimicrobial Agents - Bas\u0131nda 17 Mart 2020 - DOI : 10.1016\/j.ijantimicag.2020.105949<\/p>","protected":false},"excerpt":{"rendered":"","protected":false},"author":4,"featured_media":11134,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[419,959,28],"tags":[400,394,396,388,389,398,397,399,92,53,554,395,250,393],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Coronavirus Covid-19: hydroxychloroquine, the new hope?<\/title>\n<meta name=\"description\" content=\"Hydroxycholoquine is the new hope for coronavirus (Covid-19) infection. New paper shows exciting clinical results from a small scale study done in France.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mindthegraph.com\/blog\/tr\/coronavirus-covid-19-is-hydroxychloroquine-the-new-hope-apparently-yes\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Is Hydroxycholoquine the new hope for coronavirus (Covid-19) infected patients? Apparently, yes.\" \/>\n<meta property=\"og:description\" content=\"Hydroxycholoquine is the new hope for coronavirus (Covid-19) infection. New paper shows exciting clinical results from a small scale study done in France.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/mindthegraph.com\/blog\/tr\/coronavirus-covid-19-is-hydroxychloroquine-the-new-hope-apparently-yes\/\" \/>\n<meta property=\"og:site_name\" content=\"Mind the Graph Blog\" \/>\n<meta property=\"article:published_time\" content=\"2020-03-20T11:22:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-10-18T11:09:52+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2020\/03\/image-192.png\" \/>\n\t<meta property=\"og:image:width\" content=\"607\" \/>\n\t<meta property=\"og:image:height\" content=\"480\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Fabricio Pamplona\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:title\" content=\"Is Hydroxycholoquine the new hope for coronavirus (Covid-19) infected patients? Apparently, yes.\" \/>\n<meta name=\"twitter:description\" content=\"Hydroxycholoquine is the new hope for coronavirus (Covid-19) infection. New paper shows exciting clinical results from a small scale study done in France.\" \/>\n<meta name=\"twitter:image\" content=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2020\/03\/image-192.png\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Fabricio Pamplona\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Coronavirus Covid-19: hydroxychloroquine, the new hope?","description":"Hydroxycholoquine is the new hope for coronavirus (Covid-19) infection. New paper shows exciting clinical results from a small scale study done in France.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/mindthegraph.com\/blog\/tr\/coronavirus-covid-19-is-hydroxychloroquine-the-new-hope-apparently-yes\/","og_locale":"tr_TR","og_type":"article","og_title":"Is Hydroxycholoquine the new hope for coronavirus (Covid-19) infected patients? Apparently, yes.","og_description":"Hydroxycholoquine is the new hope for coronavirus (Covid-19) infection. New paper shows exciting clinical results from a small scale study done in France.","og_url":"https:\/\/mindthegraph.com\/blog\/tr\/coronavirus-covid-19-is-hydroxychloroquine-the-new-hope-apparently-yes\/","og_site_name":"Mind the Graph Blog","article_published_time":"2020-03-20T11:22:00+00:00","article_modified_time":"2022-10-18T11:09:52+00:00","og_image":[{"width":607,"height":480,"url":"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2020\/03\/image-192.png","type":"image\/png"}],"author":"Fabricio Pamplona","twitter_card":"summary_large_image","twitter_title":"Is Hydroxycholoquine the new hope for coronavirus (Covid-19) infected patients? Apparently, yes.","twitter_description":"Hydroxycholoquine is the new hope for coronavirus (Covid-19) infection. New paper shows exciting clinical results from a small scale study done in France.","twitter_image":"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2020\/03\/image-192.png","twitter_misc":{"Written by":"Fabricio Pamplona","Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/mindthegraph.com\/blog\/coronavirus-covid-19-is-hydroxychloroquine-the-new-hope-apparently-yes\/","url":"https:\/\/mindthegraph.com\/blog\/coronavirus-covid-19-is-hydroxychloroquine-the-new-hope-apparently-yes\/","name":"Coronavirus Covid-19: hydroxychloroquine, the new hope?","isPartOf":{"@id":"https:\/\/mindthegraph.com\/blog\/#website"},"datePublished":"2020-03-20T11:22:00+00:00","dateModified":"2022-10-18T11:09:52+00:00","author":{"@id":"https:\/\/mindthegraph.com\/blog\/#\/schema\/person\/c8eaee6d8007ac319523c3ddc98cedd3"},"description":"Hydroxycholoquine is the new hope for coronavirus (Covid-19) infection. New paper shows exciting clinical results from a small scale study done in France.","breadcrumb":{"@id":"https:\/\/mindthegraph.com\/blog\/coronavirus-covid-19-is-hydroxychloroquine-the-new-hope-apparently-yes\/#breadcrumb"},"inLanguage":"tr-TR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/mindthegraph.com\/blog\/coronavirus-covid-19-is-hydroxychloroquine-the-new-hope-apparently-yes\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/mindthegraph.com\/blog\/coronavirus-covid-19-is-hydroxychloroquine-the-new-hope-apparently-yes\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/mindthegraph.com\/blog\/"},{"@type":"ListItem","position":2,"name":"Coronavirus (Covid-19): is hydroxychloroquine the new hope? Apparently, yes."}]},{"@type":"WebSite","@id":"https:\/\/mindthegraph.com\/blog\/#website","url":"https:\/\/mindthegraph.com\/blog\/","name":"Mind the Graph Blog","description":"Your science can be beautiful!","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/mindthegraph.com\/blog\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"tr-TR"},{"@type":"Person","@id":"https:\/\/mindthegraph.com\/blog\/#\/schema\/person\/c8eaee6d8007ac319523c3ddc98cedd3","name":"Fabricio Pamplona","image":{"@type":"ImageObject","inLanguage":"tr-TR","@id":"https:\/\/mindthegraph.com\/blog\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/da6985d9f20ecb24f3238df103a638ac?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/da6985d9f20ecb24f3238df103a638ac?s=96&d=mm&r=g","caption":"Fabricio Pamplona"},"description":"Fabricio Pamplona is the founder of Mind the Graph - a tool used by over 400K users in 60 countries. He has a Ph.D. and solid scientific background in Psychopharmacology and experience as a Guest Researcher at the Max Planck Institute of Psychiatry (Germany) and Researcher in D'Or Institute for Research and Education (IDOR, Brazil). Fabricio holds over 2500 citations in Google Scholar. He has 10 years of experience in small innovative businesses, with relevant experience in product design and innovation management. Connect with him on LinkedIn - Fabricio Pamplona.","sameAs":["http:\/\/mindthegraph.com","https:\/\/www.linkedin.com\/in\/fabriciopamplona"],"url":"https:\/\/mindthegraph.com\/blog\/tr\/author\/fabricio\/"}]}},"_links":{"self":[{"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/posts\/10972"}],"collection":[{"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/comments?post=10972"}],"version-history":[{"count":11,"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/posts\/10972\/revisions"}],"predecessor-version":[{"id":16041,"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/posts\/10972\/revisions\/16041"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/media\/11134"}],"wp:attachment":[{"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/media?parent=10972"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/categories?post=10972"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/tr\/wp-json\/wp\/v2\/tags?post=10972"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}