{"id":16657,"date":"2022-09-14T13:04:15","date_gmt":"2022-09-14T16:04:15","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=16657"},"modified":"2023-03-17T14:47:26","modified_gmt":"2023-03-17T17:47:26","slug":"success-case-xtalkdb-a-database-of-signaling-pathway-crosstalk","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/sv_se\/framgang-fall-xtalkdb-a-databas-av-signalering-pathway-crosstalk\/","title":{"rendered":"XTALKDB: en databas \u00f6ver signalv\u00e4gars \u00f6verlappning Paper Review"},"content":{"rendered":"

Denna fantastiska artikel tar fram statistik som sammanfattar data i XTALKDB. P\u00e5 bara n\u00e5gra minuter skapade f\u00f6rfattaren en infografik som f\u00f6rklarar f\u00f6rdelningen av arterna i XTALKDB.<\/p>\n\n\n\n

Kontrollera originalartikel h\u00e4r<\/a>.<\/p>\n\n\n\n

Eftersom m\u00e4nniskor \u00e4r visuella varelser \u00e4r bilder fortfarande det b\u00e4sta s\u00e4ttet att f\u00f6rklara din forskning med s\u00e5 m\u00e5nga detaljer som du vill.<\/p>\n\n\n\n

Forskare har utvecklat en databas som dokumenterar samverkan mellan specifika par av signalv\u00e4gar och de arter och v\u00e4vnader d\u00e4r de observeras<\/strong><\/h2>\n\n\n\n

En forskargrupp ledd av Sarah Sam vid institutionen f\u00f6r biologiska vetenskaper (2016) rapporterade att receptorernas uppfattning av en extern signal f\u00e5r aktiviteten hos mellanliggande proteiner att f\u00f6r\u00e4ndras. <\/p>\n\n\n\n

Detta resulterar i reglering av transkriptionsfaktorer, som modulerar uttrycket av m\u00e5lgener. F\u00f6r varje par av v\u00e4gar registrerar XTalkDB detaljerad information som beskriver de experimentella f\u00f6rh\u00e5llanden under vilka korsstalk uppt\u00e4cktes. <\/p>\n\n\n\n

Celler utv\u00e4rderar och reagerar p\u00e5 sin omgivning via signalv\u00e4gar. En signalv\u00e4g inneh\u00e5ller vanligtvis en v\u00e4ldefinierad upps\u00e4ttning reglerande och fysiska interaktioner mellan receptorer, intermedi\u00e4ra signalproteiner, transkriptionsfaktorer och m\u00e5lgener. <\/p>\n\n\n\n

Webbplatsen XTalkDB erbjuder ett l\u00e4ttanv\u00e4nt gr\u00e4nssnitt f\u00f6r forskare att bl\u00e4ddra i information om korstalk genom att st\u00e4lla fr\u00e5gor om en eller flera v\u00e4gar eller molekyler av intresse.<\/p>\n\n\n\n

Det var 650 par som ingick i studien.<\/strong><\/p>\n\n\n\n

Grafisk sammanfattning baserad p\u00e5 Mind the Graph<\/strong><\/h2>\n\n\n
\n
\"framg\u00e5ng-fall-XTALKDB-a-databas-av-signalering-v\u00e4g-crosstalk\"<\/a>
Tillverkad med Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n

\"Den manuella kurateringsprocessen som ligger till grund f\u00f6r XTalkDB har sina begr\u00e4nsningar, s\u00e4rskilt n\u00e4r vi f\u00f6rs\u00f6ker ut\u00f6ka databasens t\u00e4ckning. <\/p>\n\n\n\n

Vi planerar att utveckla ett ramverk f\u00f6r bearbetning av naturligt spr\u00e5k som kommer att bed\u00f6ma publikationer baserat p\u00e5 deras sannolikhet att dokumentera \u00f6verh\u00f6rning. En kurator kan sedan fokusera p\u00e5 h\u00f6gt rankade publikationer\", medger de.<\/p>\n\n\n\n

Pappers p\u00e5verkan och prestanda<\/strong><\/h2>\n\n\n\n

Vi kan analysera med Altmetrisk<\/a> uppgifter om att detta papper \u00e4r p\u00e5 \u00f6versta delen av alla m\u00e4tv\u00e4rden i alla artiklar som finansierats av NIH i Dimensions. <\/strong><\/p>\n\n\n

\n
\"\"<\/a>
K\u00e4lla: https:\/\/badge.dimensions.ai\/details\/id\/pub.1052462103<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n

Anv\u00e4nd kraften i infografik f\u00f6r att boosta din artikel ocks\u00e5. Prova Mind the Graph!<\/p>\n\n\n\n

<\/div>\n\n\n\n
\n
F\u00f6rs\u00f6k Mind the Graph<\/strong><\/a><\/div>\n<\/div>\n\n\n\n
<\/div>","protected":false},"excerpt":{"rendered":"

L\u00e4r dig av dem som redan har uppt\u00e4ckt kraften i infografik. Denna artikel har grafiska abstraktioner gjorda med Mind the Graph. <\/p>","protected":false},"author":29,"featured_media":20046,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[195,958,957,960,1],"tags":[96,554,963],"yoast_head":"\nXTALKDB: a database of signaling pathway crosstalk Paper Review - Mind the Graph Blog<\/title>\n<meta name=\"description\" content=\"This amazing article brings out statistics summarizing data in XTALKDB with an infographic explaining the distribution of the species in XTALKDB.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mindthegraph.com\/blog\/sv_se\/framgang-fall-xtalkdb-a-databas-av-signalering-pathway-crosstalk\/\" \/>\n<meta property=\"og:locale\" content=\"sv_SE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"XTALKDB: a database of signaling pathway crosstalk Paper Review - 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