{"id":16092,"date":"2022-07-22T14:22:56","date_gmt":"2022-07-22T17:22:56","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=16092"},"modified":"2022-10-18T08:29:39","modified_gmt":"2022-10-18T11:29:39","slug":"covid-or-the-effect-of-vaccination","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/sv_se\/covid-eller-effekten-av-vaccination\/","title":{"rendered":"\u00c4r det covid-19 eller effekten av vaccination? Kardiovaskul\u00e4ra n\u00f6dsituationer"},"content":{"rendered":"

Efter att ha tagit sig igenom de sv\u00e5raste tiderna med covid-19 har m\u00e4nskligheten funnit hopp i vaccinering. Alla de nya biotekniska framstegen gjorde det m\u00f6jligt f\u00f6r oss att bek\u00e4mpa de sv\u00e5ra tiderna med covid-19. \u00c4rligt talat, tiden var knapp och m\u00e4nniskor dog. M\u00e4nskligheten k\u00e4mpade inte bara f\u00f6r att hitta en orsak utan ocks\u00e5 f\u00f6r att \u00f6verleva! <\/p>\n\n\n\n

En tv\u00e4rvetenskaplig strategi, snabbare lagstiftnings\u00e5tg\u00e4rder och st\u00f6d fr\u00e5n samh\u00e4llet blev verktyg f\u00f6r att bek\u00e4mpa pandemin. Behovet av att hantera den tidspress som covid-19 st\u00e4llde oss inf\u00f6r ledde till faktasp\u00e5rning av vaccintillverkningen, men man str\u00e4vade ocks\u00e5 efter snabbare godk\u00e4nnanden utan att studera de l\u00e5ngsiktiga effekterna av nyutvecklade molekyler.<\/p>\n\n\n\n

Alla krafter f\u00f6rs\u00f6kte begr\u00e4nsa spridningen av det ok\u00e4nda hotet och lagren av medicinska tj\u00e4nster h\u00f6ll p\u00e5 att falla samman! Under dessa \u00f6gonblick f\u00f6reslogs och testades vaccinmolekyler. Sjukdomen i sig var inte helt k\u00e4nd och de l\u00e5ngsiktiga effekterna l\u00e4t som ett svart h\u00e5l. Alla nationer och regeringar enades om att tillhandah\u00e5lla gratis vaccinering f\u00f6r att r\u00e4dda m\u00e4nniskor, men ur vetenskaplig synvinkel har det funnits m\u00e5nga spekulationer om vad som kommer att bli kort- och l\u00e5ngtidseffekter av COVID-vaccinationsinsatser p\u00e5 individer.<\/p>\n\n\n\n

Tre \u00e5r efter det f\u00f6rsta utbrottet av sjukdomen har forskare nu b\u00f6rjat analysera data i detalj f\u00f6r att hitta korrelationer och trender med hj\u00e4lp av olika j\u00e4mf\u00f6relser. Med denna nya typ av artikel fr\u00e5n Mind the Graph f\u00f6rs\u00f6ker vi ge insikter i de mest l\u00e4sta artiklarna i k\u00e4nda tidskrifter under en period. V\u00e5ra experter kommer att g\u00e5 igenom artiklarna, f\u00f6rbereda grafiska representationer och servera dem f\u00f6r att b\u00e4st f\u00f6rst\u00e5 v\u00e5ra \u00e5sikter. Vi vill inte att du ska missa n\u00e5gra bra artiklar eller tekniska uppdateringar som vi kan belysa.<\/p>\n\n\n\n

Den forskningsartikel som vi presenterar den h\u00e4r veckan har titeln, \"\u00d6kade akuta kardiovaskul\u00e4ra h\u00e4ndelser bland befolkningen under 40 \u00e5r i Israel under vaccinutrullningen och den tredje covid-19-v\u00e5gen\"<\/a> och den talar fr\u00e4mst om de hj\u00e4rtsjukdomar som noterats efter covid-19-vaccinationen och j\u00e4mf\u00f6r dem retrospektivt med covid-19-hj\u00e4rtsjukdomar.<\/p>\n\n\n\n

Innan vi b\u00f6rjar titta n\u00e4rmare p\u00e5 artikelns metodik och observation b\u00f6r vi b\u00f6rja med att f\u00e5 en grundl\u00e4ggande f\u00f6rst\u00e5else f\u00f6r den vaccinvetenskapliga processen f\u00f6r vaccinutveckling.<\/p>\n\n\n\n

Vacciner - vad \u00e4r de?<\/strong><\/strong><\/h2>\n\n\n\n

Enligt ordbokens definition \u00e4r vacciner sm\u00e5 immunogena partiklar, suspensioner av f\u00f6rsvagade, avd\u00f6dade eller fragmenterade mikroorganismer eller toxiner eller andra biologiska preparat, t.ex. s\u00e5dana som best\u00e5r av antikroppar, lymfocyter eller budb\u00e4rar-RNA (mRNA), som huvudsakligen administreras f\u00f6r att f\u00f6rebygga sjukdom. N\u00e4r m\u00e4nniskokroppen exponeras f\u00f6r f\u00f6rsvagade antigenpartiklar tenderar de att framkalla ett immunologiskt svar fr\u00e5n v\u00e4rdkroppen, men inte n\u00f6dv\u00e4ndigtvis sjukdom.<\/p>\n\n\n\n

Vaccinmolekylerna liknar patogener och framkallar ett immunsvar som aktiverar IGg-producerande B-celler och leder till att ett minne bildas f\u00f6r antikroppsproduktion mot molekylen. Denna mekanism hj\u00e4lper m\u00e4nniskor att f\u00e5 ett l\u00e5ng- och kortsiktigt skydd mot infektionen. COVID-vaccinerna utvecklas ocks\u00e5 av l\u00e4kemedelsf\u00f6retag f\u00f6r att skydda oss fr\u00e5n sjukdomens d\u00f6dliga prognos och d\u00f6d.<\/p>\n\n\n\n

COVID-komplikationer<\/strong><\/strong><\/h2>\n\n\n\n

SARS COVID 19-viruset har hotat m\u00e4nniskans existens i grunden. M\u00e5nadens artikel handlar om olika hj\u00e4rtkomplikationer som orsakas av sjukdomen under dess infektionscykel och dess l\u00e5ngsiktiga effekter. F\u00f6rfattarna, Christopher L.F., Eli Jaffe & Retsef Levi fr\u00e5n Israel, har gett en kortfattad f\u00f6rst\u00e5else av de kardiovaskul\u00e4ra komplikationer som COVID orsakar.<\/p>\n\n\n\n

De n\u00e4mner att blodproppar, akut koronarsyndrom, hj\u00e4rtstillest\u00e5nd och myokardit \u00e4r vanliga biverkningar av COVID. Det finns rapporterade fall av multipel organp\u00e5verkan vid covid-19 och under v\u00e5rd efter covid-19. Hos \u00e4ldre blir det sv\u00e5rt att skilja p\u00e5 effekten av sjukdomen och effekten av \u00e5lder och redan existerande kliniska tillst\u00e5nd. Studien som presenteras av f\u00f6rfattarna v\u00e4cker d\u00e4rf\u00f6r verkligen v\u00e5r uppm\u00e4rksamhet p\u00e5 grund av r\u00e5dande medicinska n\u00f6dsituationer. <\/p>\n\n\n\n

F\u00f6rfattarna konstaterade att det m\u00e5ste finnas ett visst samband mellan det \u00f6kade antalet n\u00f6dsituationer som tas emot av den nationella hj\u00e4lplinjen och tidslinjen f\u00f6r vaccination. Det kr\u00e4vdes dock en noggrann och komplicerad studiedesign f\u00f6r att f\u00f6rst\u00e5 de fina gr\u00e4nserna mellan effekterna efter covid-19 eller effekterna av vaccinationen, eller \u00e5ldersrelaterade resultat och n\u00f6dsituationer.<\/p>\n\n\n\n

Utmaningar f\u00f6r forskare - utformning av studien <\/strong><\/strong><\/h2>\n\n\n\n

Forskningsartikeln bygger p\u00e5 en retrospektiv befolkningsbaserad unders\u00f6kning av r\u00e4ddningstj\u00e4nsten i Israel. Syftet med studien \u00e4r att unders\u00f6ka hur ytterligare datak\u00e4llor, t.ex. fr\u00e5n akutsjukv\u00e5rden, kan komplettera sj\u00e4lvrapporterande vaccin\u00f6vervakningssystem f\u00f6r att identifiera covid-19-relaterade folkh\u00e4lsotrender. <\/p>\n\n\n\n

I sina egna ord, \"Med hj\u00e4lp av en unik dataset fr\u00e5n Israel National Emergency Medical Services (EMS) fr\u00e5n 2019 till 2021, syftar studien till att utv\u00e4rdera sambandet mellan volymen av hj\u00e4rtstopp och akut koronarsyndrom EMS-samtal i den 16-39-\u00e5riga befolkningen med potentiella faktorer inklusive COVID-19-infektion och vaccinationsniv\u00e5er. <\/p>\n\n\n\n

Forskarna anv\u00e4nde negativa binomiala regressionsmodeller f\u00f6r att analysera de veckovisa n\u00f6dsamtalen och f\u00f6rs\u00f6kte relatera dem till den f\u00f6rsta och andra dosen av COVID-vacciner. Alla datak\u00e4llor var nationella datainsamlingscenter.<\/p>\n\n\n\n

<\/p>\n\n\n\n

\"\"<\/a>
Fr\u00e5n:\u00a0Fler akuta kardiovaskul\u00e4ra h\u00e4ndelser bland personer under 40 \u00e5r i Israel under inf\u00f6randet av vaccinet och den tredje covid-19-v\u00e5gen<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n\n

Observationer <\/strong><\/strong><\/h2>\n\n\n\n

Det visade sig att de var signifikant associerade med frekvensen av f\u00f6rsta och andra vaccindoser som administrerades till denna \u00e5ldersgrupp, men inte med COVID-19-infektionsfrekvensen. F\u00f6rfattarna f\u00f6resl\u00e5r inte bara forskningsobservationer utan de f\u00f6resl\u00e5r ocks\u00e5 vissa politiska konsekvenser. De f\u00f6resl\u00e5r statliga ingripanden och \u00f6kar medvetenheten f\u00f6r patienter och kliniker. <\/p>\n\n\n\n

Samtidigt som de anger alla kritiska indikatorer har de ocks\u00e5 beskrivit begr\u00e4nsningen i studien att den bygger p\u00e5 aggregerade data som inte inneh\u00e5ller specifik information om de drabbade patienterna, inklusive sjukhusresultat, underliggande komorbiditeter samt vaccinations- och covid-19-positiv status.<\/p>\n\n\n\n

Mind the Graph <\/strong>hyllar f\u00f6rfattarna f\u00f6r deras fantastiska arbete och bidrag till det vetenskapliga samfundet. Dela g\u00e4rna med dig av ditt fantastiska arbete och vi kommer att be v\u00e5rt team att lyfta fram ditt fantastiska arbete med ett grafiskt abstrakt! L\u00e5t oss skapa vetenskap. <\/p>\n\n\n\n

<\/p>\n\n\n\n

<\/div>\n\n\n\n

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Den aktuella artikeln handlar om olika hj\u00e4rtkomplikationer som orsakas av covid-19 under infektionscykeln och dess l\u00e5ngsiktiga effekter. <\/p>","protected":false},"author":4,"featured_media":16097,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[419,956],"tags":[870,96,554,964],"yoast_head":"\nIs it COVID or the effect of vaccination? 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