{"id":9012,"date":"2019-06-03T11:07:17","date_gmt":"2019-06-03T14:07:17","guid":{"rendered":"https:\/\/blog.mindthegraph.com\/?p=9012"},"modified":"2022-10-18T08:23:58","modified_gmt":"2022-10-18T11:23:58","slug":"award-zika-virus-infection","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/sl\/nagrada-zika-virusna-okuzba\/","title":{"rendered":"Virus Zika: Nagrajena \u0161tudija, ki na novo osvetljuje dolgoro\u010dne posledice"},"content":{"rendered":"

Vedno je \u010dudovito prikazati znanstveno delo na\u0161ih uporabnikov. Danes vam bom predstavil brazilsko znanstvenico Isis de Souza in njeno delo z virusom zika. Isis in njeni sodelavci preu\u010dujejo vpliv oku\u017ebe z virusom Zika v zgodnjem \u017eivljenjskem obdobju pri mi\u0161ih. Isis je tudi uporabnica programa Mind the graph, v predstavitvi zmagovalke pa so uporabljeni vizualni viri iz programa Mind the graph. Na to ne bi mogli biti bolj ponosni.<\/p>\n

Kaj je virus zika?<\/strong><\/h3>\n

Virus Zika spada v dru\u017eino Flaviviridae. Ta skupina vklju\u010duje ve\u010d patogenih virusov. Najbolj znan je virus rumene mrzlice, ki je tipski virus dru\u017eine in tudi razlog za ime dru\u017eine, saj beseda flavus v latin\u0161\u010dini pomeni \"rumena\". Poleg tega so drugi flavivirusi \u0161e virus zahodnega Nila, virus denge in virus klopnega encefalitisa.<\/p>\n

Dru\u017eina Flaviviridae ima skupno velikost (40-65 nm) in virusne ovojnice, ki pokrivajo njihovo za\u0161\u010ditno ikozaedri\u010dno nukleokapsido. Tudi genetski material je RNK in se pojavljajo v elektronskem mikroskopu.<\/p>\n

Spodnja infografika prikazuje osnovno strukturo virusa zika:<\/p>\n

\"predogled_90481\"<\/a><\/p>\n

 Zika se \u0161iri predvsem z \u017eenskimi Stegomya aegypti<\/em> komar, ki potrebuje kri za odlaganje jaj\u010dec. Komar je aktiven predvsem podnevi.<\/p>\n

Zmagovalni papir<\/strong><\/h2>\n

V zadnjem \u010dasu \u0161tevilni raziskovalci preu\u010dujejo nevrolo\u0161ke motnje, povezane s prirojeno izpostavljenostjo virusu zika (ZIKV).<\/p>\n

Poleg tega je prirojena mikrocefalija eden od najbolj izrazitih u\u010dinkov, o katerih poro\u010dajo pri novorojen\u010dkih, oku\u017eenih z virusom ZIKV. Zato se raziskovalna prizadevanja osredoto\u010dajo na razumevanje mehanizmov prirojene mikrocefalije, ki jo povzro\u010da virus ZIKV.<\/p>\n

Vendar pa se ob rojstvu le pri 1 do 13% izpostavljenih plodov pojavijo telesne okvare. Poleg tega primanjkuje informacij o dolgoro\u010dnih posledicah perinatalne oku\u017ebe.<\/p>\n

Isis de Souza in njeni sodelavci so s pomo\u010djo mi\u0161i preu\u010devali vedenjske in nevropatolo\u0161ke pogoje ter kratkoro\u010dne in dolgoro\u010dne posledice ter rezultate objavili v \u010dlanku z naslovom Akutne in kroni\u010dne nevrolo\u0161ke posledice oku\u017ebe z virusom Zika v zgodnjem \u017eivljenjskem obdobju pri mi\u0161ih.<\/strong><\/p>\n

Pri ljudeh je veliko klini\u010dnih stanj, povezanih z izpostavljenostjo virusu zika, ki se pojavijo mesece ali leta po rojstvu. Tudi \u010de se dojen\u010dki ne rodijo z mikrocefalijo, se pri njih lahko pojavijo motori\u010dne motnje, kortikalna displazija, povezana z napadi, in druge nevrolo\u0161ke motnje.<\/p>\n

Po mnenju avtorjev so \"sistemsko oku\u017eili novorojene mi\u0161i divjega tipa z virusom ZIKV in izvedli dolgoro\u010dno spremljanje vedenjskih, nevropatolo\u0161kih in molekularnih posledic oku\u017ebe. Poro\u010damo o kratkoro\u010dnih in dolgoro\u010dnih zapletih po oku\u017ebi z virusom ZIKV pri mi\u0161ih in dokazujemo, da zgodnja nevtralizacija tumorskega nekroznega faktorja-\u03b1 (TNF-\u03b1) delno prepre\u010di te \u0161kodljive u\u010dinke. Na\u0161e ugotovitve razkrivajo potrebo po posebni pozornosti na morebitno breme nevropatolo\u0161kih zapletov pri otrocih in mladostnikih po prirojeni izpostavljenosti virusu ZIKV ter ka\u017eejo, da je lahko zgodnje zaviranje nevrovnetja potencialno zdravljenje za prepre\u010devanje dolgoro\u010dnih nevrolo\u0161kih posledic pri otrocih, oku\u017eenih z ZIKV.\"<\/em><\/p>\n

 Nagrada, ki jo podeljuje dru\u017eba GE Healthcare Life Sciences<\/strong><\/h2>\n

Nagrado \"Pr\u00eamio Jovem Talento em Ci\u00eancias da Vida\" ali nagrado za mlade talente na podro\u010dju znanosti o \u017eivljenju spodbujata Brazilsko zdru\u017eenje za biokemijo in molekularno biologijo ter dru\u017eba GE Healthcare Life Sciences. Znanstveni odbor je izbral pet kandidatov, ki bodo svoje delo predstavili na letnem kongresu, dogodku, ki povezuje profesorje in \u0161tudente iz vse Latinske Amerike.<\/p>\n

Odbor je izbral Isis de Oliveiro, ki je predstavila svojo \u0161tudijo o posledicah izpostavljenosti virusu zika.<\/p>\n

\"znanstvena
Isis de Oliveira predstavila svoje rezultate<\/figcaption><\/figure>\n

Napisala je sporo\u010dilo, v katerem se je zahvalila svoji univerzi in \u0161tipendiji, ki ji je omogo\u010dila \u0161tudij. Poleg tega je izrazila upanje, da bodo prihodnje generacije imele prilo\u017enost, da bi si tako kot ona prizadevale za znanstveno kariero.<\/p>\n

Isis \u010destitamo za njeno neverjetno delo! Upam, da bo s svojim delom navdihnila \u0161e ve\u010d ljudi, da postanejo znanstveniki.<\/p>\n

\u010ce \u017eelite podatke prikazati bolj nazorno, da bi lahko bolje komunicirali v znanosti, lahko poskusite s programom Mind the Graph:<\/p>\n

\"znanstvene<\/a><\/p>","protected":false},"excerpt":{"rendered":"

Vedno je \u010dudovito prikazati znanstveno delo na\u0161ih uporabnikov. Danes vam bom predstavil brazilsko znanstvenico Isis de Souza in njeno delo z virusom zika. Isis in njeni sodelavci preu\u010dujejo vpliv oku\u017ebe z virusom Zika v zgodnjem \u017eivljenjskem obdobju pri mi\u0161ih. Isis je tudi uporabnica programa mind the graph, njena predstavitev pa je zmagovalna in [...]<\/p>","protected":false},"author":11,"featured_media":9080,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"image","meta":[],"categories":[40],"tags":[299,282,554,71,775,293,316,315],"yoast_head":"\nZika virus: the award-winning study that sheds light on the future<\/title>\n<meta name=\"description\" content=\"Microcephaly is a known effect related to congenital exposure to zika virus. 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