{"id":6300,"date":"2016-10-04T14:25:20","date_gmt":"2016-10-04T17:25:20","guid":{"rendered":"https:\/\/blog.mindthegraph.com\/?p=6300"},"modified":"2022-10-18T08:10:46","modified_gmt":"2022-10-18T11:10:46","slug":"autophagy-wins-nobel-prize-medicine","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/sl\/avtofagija-zmaga-nobelovo-nagrado-medicina\/","title":{"rendered":"Avtofagija je prejela Nobelovo nagrado za medicino"},"content":{"rendered":"

Proces avtofagije je vklju\u010den v ve\u010d bolezni, kot so rak in nevrolo\u0161ke bolezni. Deluje kot notranji program za recikliranje v telesu. Vendar je moteno delovanje avtofagije povezano s Parkinsonovo boleznijo, sladkorno boleznijo, rakom in drugimi s starostjo povezanimi motnjami.<\/p>\n

Po tem kratkem uvodu o pomenu procesa avtofagije ni presenetljivo, da lahko nova odkritja na tem podro\u010dju vodijo do Nobelove nagrade. Prej\u0161nji ponedeljek je raziskovalka Yoshino Ohsumi prejela Nobelova nagrada za medicino<\/a> za opredelitev prvih bistvenih genov za avtofagijo.<\/p>\n

\"Ni mi prijetno tekmovati z veliko ljudmi, ampak mi je bolj prijetno delati nekaj, \u010desar ne po\u010dne nih\u010de drug. Na neki na\u010din je to bistvo znanosti in veselje, da nekaj odkrijem, me navdihuje.\" Yoshino Ohsumi <\/a><\/p><\/blockquote>\n

Kako je to storil Ohsumi?<\/h3>\n

Ohsumi je v svojem laboratoriju oblikoval seve kvasovk, ki so med stradanjem kopi\u010dili avtofagosome. Do tega kopi\u010denja bi lahko pri\u0161lo le, \u010de bi bili bistveni geni za avtofagijo neaktivni. Tako je Ohsumi za\u010del manipulirati celice z ve\u010d mutacijami genov in uspel spodbuditi avtofagijo.<\/p>\n

\"Avtofagija<\/a><\/p>\n

Avtofagija je bila znana \u017ee<\/h3>\n

\u010ceprav je avtofagija znana \u017ee zadnjih 50 let, je bil pomen tega procesa priznan \u0161ele v 90. letih prej\u0161njega stoletja s \u0161tudijami Ohsumija.
\nOhsumi si je za svoje delo \u017ee prislu\u017eil nekaj obo\u017eevalcev:<\/p>\n

\"Avtofagija<\/a><\/p>\n

\n

\"Zelo sem vesel, da je letos prejel Nobelovo nagrado, saj si jo je zaslu\u017eil. Njegov laboratorij se ukvarja predvsem s kvasovkami. Opravili so za\u010detne preglede, ki so omogo\u010dili odkritje klju\u010dnih genov, ki sodelujejo pri avtofagiji. Toliko drugih laboratorijev je neposredno ali posredno izkoristilo njegova odkritja, da bi ugotovili, zakaj je to pomembno pri boleznih.\"<\/p>\n

David Rubinsztein<\/a> - namestnik direktorja In\u0161tituta za medicinske raziskave v Cambridgeu<\/p>\n<\/blockquote>\n

\"Avtofagija<\/a><\/p>\n

\n

\"Menim, da je zelo pomembno, da je to podro\u010dje znanosti priznano. Pri tem je pomembno na\u010delo, da gre za iskanje skupnih mehanizmov pri boleznih. To odpira poti za zdravljenje teh motenj, ki se razlikujejo od bolj obi\u010dajnih pristopov za posamezne bolezni.\"<\/p>\n

Giovanna Mallucci<\/a> - profesor klini\u010dne nevroznanosti na Univerzi v Cambridgeu<\/p>\n<\/blockquote>\n

\"Avtofagija<\/a><\/p>","protected":false},"excerpt":{"rendered":"

Proces avtofagije je vklju\u010den v ve\u010d bolezni, kot so rak in nevrolo\u0161ke bolezni. Deluje kot notranji program za recikliranje v telesu. Vendar je moteno delovanje avtofagije povezano s Parkinsonovo boleznijo, sladkorno boleznijo, rakom in drugimi s starostjo povezanimi motnjami. Po tem kratkem uvodu o pomenu procesa avtofagije ni presenetljivo, da so nova odkritja [...]<\/p>","protected":false},"author":11,"featured_media":6304,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"image","meta":[],"categories":[959,28],"tags":[554],"yoast_head":"\nAutophagy wins Nobel Prize in medicine - Mind the Graph Blog<\/title>\n<meta name=\"description\" content=\""I find it more enjoyable doing something nobody else is doing. 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