{"id":16662,"date":"2022-09-22T19:23:00","date_gmt":"2022-09-22T22:23:00","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=16662"},"modified":"2023-03-17T14:46:01","modified_gmt":"2023-03-17T17:46:01","slug":"success-case-nmda-receptor-adjusted-co-administration-of-ecstasy-and-cannabinoid-receptor-1-agonist","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/sl\/uspeh-primera-nmda-receptor-prilagojenega-co-dajanja-ekstaze-in-kanabinoidnega-receptorja-1-agonista\/","title":{"rendered":"NMDA receptorjem prilagojeno so\u010dasno dajanje ekstazija in agonista kanabinoidnega receptorja-1 v amigdali prek stimulacije poti BDNF\/Trk-B\/CREB pri odraslih samcih podgan Pregled \u010dlankov"},"content":{"rendered":"<p>Grafi\u010dni povzetki postajajo zelo priljubljeni med akademiki. To pomeni, da je avtor ustvaril neverjeten dizajn, ki z natan\u010dnimi slikami pojasnjuje celotno bistvo tega \u010dlanka.<\/p>\n\n\n\n<p>Preverite celoten <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0361923016303756\" target=\"_blank\" rel=\"noreferrer noopener\">izvirni \u010dlanek<\/a>.<\/p>\n\n\n\n<h2><strong>U\u017eivanje selektivnega agonista CB-1, kot je ACPA, \u0161\u010diti nevrone pred toksi\u010dnostjo MDMA v amigdali<\/strong><\/h2>\n\n\n\n<p>Ashabi in sodelavci (2017) so v \u010dlanku \"NMDA receptorjem prilagojeno so\u010dasno dajanje ekstazija in agonista kanabinoidnega receptorja 1 v amigdali prek stimulacije poti BDNF\/Trk-B\/CREB pri odraslih samcih podgan\" zapisali, da blokada NMDA zmanj\u0161a hitrost streljanja nevronov in raven tirozin-kinaze B\/nevrotrofi\u010dnega faktorja, ki izhaja iz mo\u017eganov, ter vezave elementov, ki se odzivajo na kemijsko aktivnost, pri podganah s so\u010dasnim dajanjem MDMA in agonista CB1 receptorjev. <\/p>\n\n\n\n<p>Glutamatergi\u010dni sistem uravnava za\u0161\u010ditno vlogo kombinacije MDMA in ACPA prek receptorjev TrK-B.<\/p>\n\n\n\n<h2><strong>Grafi\u010dni povzetki, ki jih poganja Mind the Graph<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" loading=\"lazy\" width=\"835\" height=\"305\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264.png\" alt=\"\" class=\"wp-image-20094\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264.png 835w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264-300x110.png 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264-768x281.png 768w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264-18x7.png 18w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264-100x37.png 100w\" sizes=\"(max-width: 835px) 100vw, 835px\" \/><figcaption class=\"wp-element-caption\"><em>Izdelano z&nbsp;<a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure>\n\n\n\n<p>Aktivacija receptorjev CB1 ali indukcija MDMA sta zmanj\u0161ali hitrost streljanja nevronov. Hkratna injekcija teh dveh zdravil je pove\u010dala pre\u017eivetje nevronskih celic, te dogodke pa je obrnil antagonist receptorjev NMDA. <\/p>\n\n\n\n<p>Za\u0161\u010ditna vloga glutamatergi\u010dnih receptorjev je verjetno posledica aktivacije poti BDNF\/Trk-B. <\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" loading=\"lazy\" width=\"718\" height=\"512\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785.png\" alt=\"\" class=\"wp-image-20093\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785.png 718w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785-300x214.png 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785-18x12.png 18w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785-100x71.png 100w\" sizes=\"(max-width: 718px) 100vw, 718px\" \/><figcaption class=\"wp-element-caption\"><em>Izdelano z&nbsp;<a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure>\n\n\n\n<h2><strong>U\u010dinek in uspe\u0161nost dokumentov<\/strong><\/h2>\n\n\n\n<p>\u010ce izberemo enoletno mo\u017enost primerjave metrike z drugimi \u010dlanki\/recenzijami, ki so bili prav tako objavljeni v istem koledarskem letu v tej reviji, lahko opazimo, da <strong>ta \u010dlanek je bil bolj citiran kot 47% od njih<\/strong>.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" loading=\"lazy\" width=\"377\" height=\"330\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1.png\" alt=\"\" class=\"wp-image-20096\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1.png 377w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1-300x263.png 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1-14x12.png 14w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1-100x88.png 100w\" sizes=\"(max-width: 377px) 100vw, 377px\" \/><\/figure>\n\n\n\n<p>Izkoristite mo\u010d infografike tudi za izbolj\u0161anje svojega \u010dlanka. Preizkusite Mind the Graph!<\/p>","protected":false},"excerpt":{"rendered":"<p>U\u010dite se s tistimi, ki so \u017ee odkrili mo\u010d infografike. Ta \u010dlanek vsebuje grafi\u010dne izvle\u010dke, narejene s programom Mind the Graph. <\/p>","protected":false},"author":29,"featured_media":20081,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[195,958,957,960,1],"tags":[96,963],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>NMDA receptor adjusted co-administration of ecstasy and cannabinoid receptor-1 agonist in the amygdala via stimulation of BDNF\/Trk-B\/CREB pathway in adult male rats Paper Review - Mind the Graph Blog<\/title>\n<meta name=\"description\" content=\"Learn with the ones who already discovered the power of infographics. 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