{"id":16651,"date":"2022-09-12T18:50:00","date_gmt":"2022-09-12T21:50:00","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=16651"},"modified":"2023-03-17T14:47:35","modified_gmt":"2023-03-17T17:47:35","slug":"success-case-immunotherapeutic-potential-of-crotoxin-anti-inflammatory-and-immunosuppressive-properties","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/sl\/primer-uspeha-imunoterapevtskega-potenciala-krotoksina-protivnetnih-in-imunosupresivnih-slastnosti\/","title":{"rendered":"Imunoterapevtski potencial krotoksina: protivnetne in imunosupresivne lastnosti"},"content":{"rendered":"<p>Protivnetno modulacijo krotoksina bi bilo te\u017eko razlo\u017eiti brez ustreznih slik, vendar zato obstaja Mind the Graph!<\/p>\n\n\n\n<h2><strong>Pregled znanstvenih raziskav o krotoksinu, strupu gr\u010daste ka\u010de<\/strong><\/h2>\n\n\n\n<p>Marco Sartim in drugi (2018) so v \u010dlanku \"Immunotherapeutic potential of Crotoxin\" zapisali, da je v zadnjih 80 letih krotoksin postal eden najbolj raziskanih izoliranih toksinov iz ka\u010djih strupov. <\/p>\n\n\n\n<p>Krotoksin je glavna strupena sestavina v strupu ju\u017enoameri\u0161kih \u0161\u010durkov Crotalus durissus terrificus. \u0160tudije so pokazale, da je imunomodulatorni u\u010dinek C.d.t. povezan s proizvodnjo protivnetnih mediatorjev. <\/p>\n\n\n\n<p>Sposobnost krotoksina in njegovih podenot, da modulirajo imunski sistem, je prinesla nove perspektive kot potencialna terapevtska sredstva.<\/p>\n\n\n\n<p><strong>Raziskovalci so pregledali 161 \u010dlankov.<\/strong><\/p>\n\n\n\n<p>Preverite <a href=\"https:\/\/jvat.biomedcentral.com\/articles\/10.1186\/s40409-018-0178-3\" target=\"_blank\" rel=\"noreferrer noopener\">izvirni \u010dlanek tukaj<\/a>.<\/p>\n\n\n\n<h2><strong>Grafi\u010dni povzetki, ki jih poganja Mind the Graph<\/strong><\/h2>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html.webp\"><img decoding=\"async\" loading=\"lazy\" width=\"1024\" height=\"1003\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-1024x1003.webp\" alt=\"\" class=\"wp-image-20251\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-1024x1003.webp 1024w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-300x294.webp 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-768x752.webp 768w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-12x12.webp 12w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-100x98.webp 100w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html.webp 1418w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><figcaption class=\"wp-element-caption\"><em>Izdelano z <a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>Avtor je uporabil platformo Mind the Graph za izdelavo shematskega prikaza cirkulacije, tkivnih in celi\u010dnih dogodkov, ki jih med vnetno spodbudo modulirajo krotoksin in njegove podenote.<\/p>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_Fig3_HTML.webp\"><img decoding=\"async\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_Fig3_HTML-839x1024.webp\" alt=\"\" class=\"wp-image-20252\"\/><\/a><figcaption class=\"wp-element-caption\"><em>Izdelano z <a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>Avtor je podrobno opisal tudi krvni obtok, usmerjanje limfocitov v bezgavke in celi\u010dne dogodke, povezane z imunosupresivnimi u\u010dinki krotoksina in njegovih podenot.<\/p>\n\n\n\n<p><strong>To je mo\u010d infografike!<\/strong><\/p>\n\n\n\n<p>Zdi se, da sklepi avtorjev utrjujejo predhodno delo na tem podro\u010dju: \"Krotoksin je lahko zaviral proizvodnjo specifi\u010dnih protiteles antiHSA IgG1 in IgG2a pri mi\u0161ih, imuniziranih s HAS, kar ka\u017ee na njegovo sposobnost moduliranja odzivov Th1 in Th2,\" trdi Sartim.<\/p>\n\n\n\n<h2><strong>U\u010dinek in uspe\u0161nost dokumentov<\/strong><\/h2>\n\n\n\n<p>Analiziramo lahko z <a href=\"https:\/\/mindthegraph.com\/blog\/altmetric\/\" target=\"_blank\" rel=\"noreferrer noopener\">Altmetric<\/a> podatkov, da je imel ta dokument ve\u010d citatov. <strong>kot . <strong>84%<\/strong><\/strong> <strong>drugih \u010dlankov iz revije Springer Nature.<\/strong><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1.png\"><img decoding=\"async\" loading=\"lazy\" width=\"322\" height=\"578\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1.png\" alt=\"\" class=\"wp-image-20254\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1.png 322w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1-167x300.png 167w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1-7x12.png 7w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1-56x100.png 56w\" sizes=\"(max-width: 322px) 100vw, 322px\" \/><\/a><figcaption class=\"wp-element-caption\"><em>Vir: <a href=\"https:\/\/citations.springernature.com\/item?doi=10.1186\/s40409-018-0178-3&amp;start=11&amp;years=&amp;journals=&amp;books=&amp;authors=\" target=\"_blank\" rel=\"noreferrer noopener\">Crossref<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>Uporabite mo\u010d infografike za pove\u010danje in <a href=\"https:\/\/mindthegraph.com\/blog\/research-journal-impact-factor\/\">vpliv va\u0161ega \u010dlanka<\/a> prav tako. Poskusite Mind the Graph!<\/p>\n\n\n\n<div class=\"is-layout-flex wp-block-buttons\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-background wp-element-button\" href=\"https:\/\/mindthegraph.com\/app\/auth\/register?from_url=\/\" style=\"border-radius:100px;background-color:#dc1866\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Poskusite Mind the Graph<\/strong><\/a><\/div>\n<\/div>\n\n\n\n<div style=\"height:46px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Protivnetno modulacijo krotoksina bi bilo te\u017eko razlo\u017eiti brez ustreznih slik, vendar Mind the Graph obstaja!<\/p>","protected":false},"author":29,"featured_media":20047,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[195,958,957,960,1],"tags":[96,554,963],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Immunotherapeutic potential of Crotoxin: anti-inflammatory and immunosuppressive properties Paper Review - 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