{"id":16662,"date":"2022-09-22T19:23:00","date_gmt":"2022-09-22T22:23:00","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=16662"},"modified":"2023-03-17T14:46:01","modified_gmt":"2023-03-17T17:46:01","slug":"success-case-nmda-receptor-adjusted-co-administration-of-ecstasy-and-cannabinoid-receptor-1-agonist","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/sk\/uspesnost-pripadu-nmda-receptora-prisposobeneho-podavaniu-ekstazy-a-kanabinoidneho-receptora-1-agonistu\/","title":{"rendered":"NMDA receptor upraven\u00fd s\u00fa\u010dasn\u00fdm pod\u00e1van\u00edm ext\u00e1zy a agonistu kanabinoidn\u00e9ho receptora-1 v amygdale prostredn\u00edctvom stimul\u00e1cie dr\u00e1hy BDNF\/Trk-B\/CREB u dospel\u00fdch samcov potkanov Paper Review"},"content":{"rendered":"<p>Grafick\u00e9 abstrakty sa medzi akademick\u00fdmi pracovn\u00edkmi st\u00e1vaj\u00fa ve\u013emi ob\u013e\u00faben\u00fdmi. To znamen\u00e1, \u017ee autor vytvoril jeden \u00fa\u017easn\u00fd dizajn, ktor\u00fd vysvet\u013euje cel\u00fa pointu tohto \u010dl\u00e1nku s presn\u00fdmi obr\u00e1zkami.<\/p>\n\n\n\n<p>Skontrolujte kompletn\u00e9 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0361923016303756\" target=\"_blank\" rel=\"noreferrer noopener\">p\u00f4vodn\u00fd \u010dl\u00e1nok<\/a>.<\/p>\n\n\n\n<h2><strong>Konzum\u00e1cia selekt\u00edvneho agonistu CB-1, ako je ACPA, chr\u00e1ni neur\u00f3ny pred toxicitou MDMA v amygdale<\/strong><\/h2>\n\n\n\n<p>V pr\u00e1ci \"NMDA receptor upravuje s\u00fa\u010dasn\u00e9 pod\u00e1vanie ext\u00e1zy a agonistu kanabinoidn\u00e9ho receptora 1 v amygdale prostredn\u00edctvom stimul\u00e1cie dr\u00e1hy BDNF\/Trk-B\/CREB u dospel\u00fdch samcov potkanov\" Ashabi a jeho kolegovia (2017) uviedli, \u017ee blok\u00e1da NMDA zn\u00ed\u017eila r\u00fdchlos\u0165 neuron\u00e1lneho vystre\u013eovania a hladinu prote\u00ednu via\u017euceho tyroz\u00ednkin\u00e1zu B\/neurotrofick\u00fd faktor odvoden\u00fd od mozgu\/element via\u017euci sa na CAMP u potkanov, ktor\u00fdm bol s\u00fa\u010dasne podan\u00fd MDMA a agonista receptora CB1. <\/p>\n\n\n\n<p>Glutamatergick\u00fd syst\u00e9m reguluje ochrann\u00fa \u00falohu kombin\u00e1cie MDMA a ACPA prostredn\u00edctvom receptorov TrK-B.<\/p>\n\n\n\n<h2><strong>Grafick\u00e9 abstrakty zalo\u017een\u00e9 na Mind the Graph<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" loading=\"lazy\" width=\"835\" height=\"305\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264.png\" alt=\"\" class=\"wp-image-20094\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264.png 835w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264-300x110.png 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264-768x281.png 768w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264-18x7.png 18w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264-100x37.png 100w\" sizes=\"(max-width: 835px) 100vw, 835px\" \/><figcaption class=\"wp-element-caption\"><em>Vyroben\u00e9 s&nbsp;<a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure>\n\n\n\n<p>Aktiv\u00e1cia receptora CB1 alebo indukcia MDMA zn\u00ed\u017eili r\u00fdchlos\u0165 vypa\u013eovania neur\u00f3nov. S\u00fa\u010dasn\u00e1 injekcia t\u00fdchto dvoch lie\u010div zv\u00fd\u0161ila pre\u017e\u00edvanie neur\u00f3nov\u00fdch buniek a tieto udalosti boli zvr\u00e1ten\u00e9 prostredn\u00edctvom antagonistu NMDA receptorov. <\/p>\n\n\n\n<p>Ochrann\u00e1 \u00faloha glutam\u00e1tergick\u00fdch receptorov m\u00f4\u017ee pravdepodobne spo\u010d\u00edva\u0165 v aktiv\u00e1cii dr\u00e1h BDNF\/Trk-B. <\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" loading=\"lazy\" width=\"718\" height=\"512\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785.png\" alt=\"\" class=\"wp-image-20093\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785.png 718w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785-300x214.png 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785-18x12.png 18w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785-100x71.png 100w\" sizes=\"(max-width: 718px) 100vw, 718px\" \/><figcaption class=\"wp-element-caption\"><em>Vyroben\u00e9 s&nbsp;<a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure>\n\n\n\n<h2><strong>Dokumenty Vplyv a v\u00fdkon<\/strong><\/h2>\n\n\n\n<p>Pri v\u00fdbere jednoro\u010dnej mo\u017enosti porovnania metr\u00edk s in\u00fdmi \u010dl\u00e1nkami\/recenziou, ktor\u00e9 boli tie\u017e publikovan\u00e9 v tom istom kalend\u00e1rnom roku v danom \u010dasopise, si m\u00f4\u017eeme v\u0161imn\u00fa\u0165, \u017ee <strong>tento \u010dl\u00e1nok bol citovan\u00fd viac ako 47% z nich<\/strong>.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" loading=\"lazy\" width=\"377\" height=\"330\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1.png\" alt=\"\" class=\"wp-image-20096\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1.png 377w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1-300x263.png 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1-14x12.png 14w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1-100x88.png 100w\" sizes=\"(max-width: 377px) 100vw, 377px\" \/><\/figure>\n\n\n\n<p>Vyu\u017eite silu infografiky aj na podporu svojho \u010dl\u00e1nku. Vysk\u00fa\u0161ajte Mind the Graph!<\/p>","protected":false},"excerpt":{"rendered":"<p>U\u010dte sa s t\u00fdmi, ktor\u00ed u\u017e objavili silu infografiky. Tento \u010dl\u00e1nok obsahuje grafick\u00e9 v\u00fd\u0148atky vytvoren\u00e9 pomocou Mind the Graph. <\/p>","protected":false},"author":29,"featured_media":20081,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[195,958,957,960,1],"tags":[96,963],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>NMDA receptor adjusted co-administration of ecstasy and cannabinoid receptor-1 agonist in the amygdala via stimulation of BDNF\/Trk-B\/CREB pathway in adult male rats Paper Review - Mind the Graph Blog<\/title>\n<meta name=\"description\" content=\"Learn with the ones who already discovered the power of infographics. 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