{"id":16092,"date":"2022-07-22T14:22:56","date_gmt":"2022-07-22T17:22:56","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=16092"},"modified":"2022-10-18T08:29:39","modified_gmt":"2022-10-18T11:29:39","slug":"covid-or-the-effect-of-vaccination","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/sk\/covid-alebo-ucinok-ockovania\/","title":{"rendered":"Je to COVID alebo \u00fa\u010dinok o\u010dkovania? Kardiovaskul\u00e1rne n\u00fadzov\u00e9 situ\u00e1cie"},"content":{"rendered":"

Po prekonan\u00ed naj\u0165a\u017e\u0161\u00edch \u010dasov COVID 19 na\u0161lo \u013eudstvo n\u00e1dej v o\u010dkovan\u00ed. V\u0161etky nov\u00e9 biotechnologick\u00e9 pokroky n\u00e1m umo\u017enili bojova\u0165 s \u0165a\u017ek\u00fdmi \u010dasmi COVID. \u00daprimne povedan\u00e9, \u010dasu bolo menej a \u013eudia umierali. \u013dudstvo sa sna\u017eilo nielen n\u00e1js\u0165 pr\u00ed\u010dinu, ale aj pre\u017ei\u0165! <\/p>\n\n\n\n

N\u00e1strojmi boja proti pand\u00e9mii sa stali multidisciplin\u00e1rny pr\u00edstup, r\u00fdchlej\u0161ie legislat\u00edvne opatrenia a podpora komunity. Potreba vyrovna\u0165 sa s \u010dasovou ties\u0148ou, ktor\u00fa u n\u00e1s predstavoval COVID, viedla k sledovaniu faktov o v\u00fdrobe vakc\u00edn, ale tie\u017e k snahe o r\u00fdchlej\u0161ie schva\u013eovanie bez sk\u00famania dlhodob\u00fdch \u00fa\u010dinkov novo vyvinut\u00fdch molek\u00fal.<\/p>\n\n\n\n

V\u0161etky sily sa sna\u017eili obmedzi\u0165 \u0161\u00edrenie nezn\u00e1mej hrozby a vrstvy zdravotn\u00edckych slu\u017eieb sa rozpadali! V t\u00fdch chv\u00ed\u013each sa navrhovali a testovali molekuly vakc\u00edn. Samotn\u00e1 choroba nebola \u00faplne zn\u00e1ma a dlhodob\u00e9 \u00fa\u010dinky zneli ako \u010dierna diera. V\u0161etky \u0161t\u00e1ty a vl\u00e1dy s\u00fahlasili s poskytnut\u00edm bezplatn\u00e9ho o\u010dkovania na z\u00e1chranu \u013eud\u00ed, av\u0161ak z vedeck\u00e9ho h\u013eadiska sa objavilo ve\u013ea dohadov o tom, ak\u00e9 v\u0161etky bud\u00fa kr\u00e1tkodob\u00e9 a dlhodob\u00e9 \u00fa\u010dinky o\u010dkovacieho \u00fasilia proti COVID na jednotlivcov.<\/p>\n\n\n\n

Po troch rokoch od vypuknutia prvej epid\u00e9mie tejto choroby za\u010dali v\u00fdskumn\u00edci podrobne analyzova\u0165 \u00fadaje, aby pomocou r\u00f4znych porovnan\u00ed zistili korel\u00e1cie a trendy. T\u00fdmto nov\u00fdm typom \u010dl\u00e1nkov od Mind the Graph sa sna\u017e\u00edme poskytn\u00fa\u0165 poh\u013ead na naj\u010d\u00edtanej\u0161ie \u010dl\u00e1nky renomovan\u00fdch \u010dasopisov za ur\u010dit\u00e9 obdobie. Na\u0161i odborn\u00edci bud\u00fa \u010dl\u00e1nky prech\u00e1dza\u0165, pripravova\u0165 grafick\u00e9 zn\u00e1zornenia a sl\u00fa\u017ei\u0165 na \u010do najlep\u0161ie pochopenie na\u0161ich n\u00e1zorov. Nechceme, aby v\u00e1m unikli \u017eiadne dobr\u00e9 \u010dl\u00e1nky a technologick\u00e9 novinky, na ktor\u00e9 m\u00f4\u017eeme vrhn\u00fa\u0165 svetlo.<\/p>\n\n\n\n

V\u00fdskumn\u00fd \u010dl\u00e1nok, ktor\u00fd predstavujeme tento t\u00fd\u017ede\u0148, m\u00e1 n\u00e1zov, \"Zv\u00fd\u0161en\u00fd v\u00fdskyt n\u00e1hlych kardiovaskul\u00e1rnych pr\u00edhod v popul\u00e1cii mlad\u0161ej ako 40 rokov v Izraeli po\u010das zav\u00e1dzania vakc\u00edny a tretej vlny COVID-19\"<\/a> a hovor\u00ed sa v nej predov\u0161etk\u00fdm o srdcov\u00fdch pr\u00edhod\u00e1ch zaznamenan\u00fdch v obdob\u00ed po o\u010dkovan\u00ed COVID a retrospekt\u00edvne sa porovn\u00e1vaj\u00fa so srdcov\u00fdmi pr\u00edhodami po o\u010dkovan\u00ed COVID.<\/p>\n\n\n\n

Sk\u00f4r ako za\u010dneme nahliada\u0165 do metodiky a pozorovania \u010dl\u00e1nku, za\u010dnime so z\u00e1kladn\u00fdm pochopen\u00edm vedeck\u00e9ho procesu v\u00fdvoja vakc\u00edn.<\/p>\n\n\n\n

\u010co s\u00fa to vakc\u00edny?<\/strong><\/strong><\/h2>\n\n\n\n

Pod\u013ea slovn\u00edkovej defin\u00edcie s\u00fa vakc\u00edny mal\u00e9 imunog\u00e9nne \u010dastice, suspenzia oslaben\u00fdch, usmrten\u00fdch alebo fragmentovan\u00fdch mikroorganizmov alebo tox\u00ednov alebo in\u00fd biologick\u00fd pr\u00edpravok, napr\u00edklad pozost\u00e1vaj\u00faci z protil\u00e1tok, lymfocytov alebo posunutej RNA (mRNA), ktor\u00fd sa pod\u00e1va predov\u0161etk\u00fdm na prevenciu ochorenia. Ke\u010f sa \u013eudsk\u00e9 telo vystav\u00ed oslaben\u00fdm \u010dasticiam antig\u00e9nu, maj\u00fa tendenciu vyvola\u0165 imunologick\u00fa odpove\u010f hostite\u013esk\u00e9ho organizmu, ale nie nevyhnutne ochorenie.<\/p>\n\n\n\n

Molekuly vakc\u00edny sa podobaj\u00fa patog\u00e9nom a vyvol\u00e1vaj\u00fa imunitn\u00fa odpove\u010f, ktor\u00e1 aktivuje B-bunky produkuj\u00face IGg a vedie k vytvoreniu pam\u00e4te na tvorbu protil\u00e1tok proti danej molekule. Tento mechanizmus pom\u00e1ha \u013eu\u010fom z\u00edska\u0165 dlhodob\u00fa - kr\u00e1tkodob\u00fa ochranu proti infekcii. Vakc\u00edny COVID vyv\u00edjaj\u00fa aj farmaceutick\u00e9 spolo\u010dnosti, aby n\u00e1s ochr\u00e1nili pred smrte\u013enou progn\u00f3zou ochorenia a smr\u0165ou.<\/p>\n\n\n\n

Komplik\u00e1cie COVID<\/strong><\/strong><\/h2>\n\n\n\n

V\u00edrus SARS COVID 19 vo svojej podstate ohrozuje \u013eudsk\u00fa existenciu. Odpor\u00fa\u010dan\u00fd \u010dl\u00e1nok mesiaca hovor\u00ed o r\u00f4znych komplik\u00e1ci\u00e1ch kardiakov sp\u00f4soben\u00fdch t\u00fdmto ochoren\u00edm po\u010das infek\u010dn\u00e9ho cyklu a o jeho dlhodob\u00fdch n\u00e1sledkoch. Autori Christopher L. F., Eli Jaffe & Retsef Levi z Izraela podali stru\u010dn\u00fd preh\u013ead kardiovaskul\u00e1rnych komplik\u00e1ci\u00ed sp\u00f4soben\u00fdch v\u00edrusom COVID.<\/p>\n\n\n\n

Uv\u00e1dzaj\u00fa, \u017ee \u010dast\u00fdmi ved\u013eaj\u0161\u00edmi \u00fa\u010dinkami lieku COVID s\u00fa zr\u00e1\u017eanie krvi, ak\u00fatny koron\u00e1rny syndr\u00f3m, z\u00e1stava srdca a myokardit\u00edda. S\u00fa hl\u00e1sen\u00e9 pr\u00edpady postihnutia viacer\u00fdch org\u00e1nov pri COVID a po\u010das starostlivosti po COVID. U star\u0161\u00edch \u013eud\u00ed je \u0165a\u017ek\u00e9 rozdeli\u0165 vplyv ochorenia a vplyv veku a u\u017e existuj\u00facich klinick\u00fdch stavov. \u0160t\u00fadia prezentovan\u00e1 autormi teda ur\u010dite up\u00fata na\u0161u pozornos\u0165 vzh\u013eadom na prevl\u00e1daj\u00face urgentn\u00e9 zdravotn\u00e9 stavy. <\/p>\n\n\n\n

Autori kon\u0161tatovali, \u017ee mus\u00ed existova\u0165 ur\u010dit\u00e1 s\u00favislos\u0165 medzi zv\u00fd\u0161en\u00fdm po\u010dtom naliehav\u00fdch pr\u00edpadov prijat\u00fdch na n\u00e1rodnej linke ties\u0148ov\u00e9ho volania a \u010dasov\u00fdm harmonogramom o\u010dkovania. Vy\u017eadovalo si to v\u0161ak d\u00f4kladn\u00fd a komplikovan\u00fd dizajn \u0161t\u00fadie, aby sa pochopila jemn\u00e1 hranica medzi vplyvom po COVID alebo vplyvom o\u010dkovania, alebo v\u00fdsledkami s\u00favisiacimi s vekom a n\u00fadzov\u00fdmi situ\u00e1ciami.<\/p>\n\n\n\n

V\u00fdzvy, ktor\u00fdm \u010delia v\u00fdskumn\u00ed pracovn\u00edci - n\u00e1vrh \u0161t\u00fadie <\/strong><\/strong><\/h2>\n\n\n\n

V\u00fdskumn\u00fd \u010dl\u00e1nok je zalo\u017een\u00fd na retrospekt\u00edvnom popula\u010dnom prieskume slu\u017eieb n\u00fadzov\u00e9ho mana\u017ementu v Izraeli. Cie\u013eom tejto \u0161t\u00fadie je presk\u00fama\u0165, ako m\u00f4\u017eu dodato\u010dn\u00e9 zdroje \u00fadajov, ako napr\u00edklad \u00fadaje od z\u00e1chrann\u00fdch zdravotn\u00fdch slu\u017eieb (EMS), doplni\u0165 syst\u00e9my doh\u013eadu nad vakc\u00ednami, ktor\u00e9 sa hl\u00e1sia samy, pri identifik\u00e1cii trendov v oblasti verejn\u00e9ho zdravia s\u00favisiacich s COVID-19. <\/p>\n\n\n\n

Pod\u013ea ich vlastn\u00fdch slov: \"S pou\u017eit\u00edm jedine\u010dn\u00e9ho s\u00faboru \u00fadajov z izraelskej n\u00e1rodnej z\u00e1chrannej zdravotnej slu\u017eby (EMS) z rokov 2019 a\u017e 2021 je cie\u013eom \u0161t\u00fadie vyhodnoti\u0165 s\u00favislos\u0165 medzi objemom volan\u00ed EMS na zastavenie srdca a ak\u00fatny koron\u00e1rny syndr\u00f3m v popul\u00e1cii 16-39 rokov s potenci\u00e1lnymi faktormi vr\u00e1tane infekcie COVID-19 a miery o\u010dkovania.\" <\/p>\n\n\n\n

V\u00fdskumn\u00edci pou\u017eili negat\u00edvne binomick\u00e9 regresn\u00e9 modely na anal\u00fdzu t\u00fd\u017edenn\u00fdch po\u010dtov ties\u0148ov\u00fdch volan\u00ed a pok\u00fasili sa ich prepoji\u0165 s 1. a 2. d\u00e1vkou vakc\u00edn COVID. V\u0161etky zdroje \u00fadajov boli n\u00e1rodn\u00e9 centr\u00e1 na zber \u00fadajov.<\/p>\n\n\n\n

<\/p>\n\n\n\n

\"\"<\/a>
Od:\u00a0Zv\u00fd\u0161en\u00fd v\u00fdskyt n\u00e1hlych kardiovaskul\u00e1rnych pr\u00edhod v popul\u00e1cii mlad\u0161ej ako 40 rokov v Izraeli po\u010das zav\u00e1dzania vakc\u00edny a tretej vlny COVID-19<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n\n

Pozorovania <\/strong><\/strong><\/h2>\n\n\n\n

Zistilo sa, \u017ee v\u00fdznamne s\u00faviseli s mierou podania 1. a 2. d\u00e1vky vakc\u00edny tejto vekovej skupine, ale nes\u00faviseli s mierou infekcie COVID-19. Autori nenazna\u010duj\u00fa len v\u00fdskumn\u00e9 pozorovania, ale nazna\u010duj\u00fa aj niektor\u00e9 politick\u00e9 d\u00f4sledky. Navrhuj\u00fa vl\u00e1dne intervencie a zv\u00fd\u0161enie informovanosti pacientov a lek\u00e1rov. <\/p>\n\n\n\n

Hoci uv\u00e1dzaj\u00fa v\u0161etky kritick\u00e9 ukazovatele, op\u00edsali aj obmedzenie \u0161t\u00fadie, ktor\u00e9 spo\u010d\u00edva v tom, \u017ee sa opiera o s\u00fahrnn\u00e9 \u00fadaje, ktor\u00e9 nezah\u0155\u0148aj\u00fa \u0161pecifick\u00e9 inform\u00e1cie t\u00fdkaj\u00face sa postihnut\u00fdch pacientov vr\u00e1tane v\u00fdsledkov hospitaliz\u00e1cie, z\u00e1kladn\u00fdch komorbid\u00edt, ako aj o\u010dkovania a pozit\u00edvneho stavu COVID-19.<\/p>\n\n\n\n

Mind the Graph <\/strong>oslavuje autorov za ich skvel\u00fa pr\u00e1cu a pr\u00ednos pre vedeck\u00fa komunitu. Pode\u013ete sa o svoju \u00fa\u017easn\u00fa pr\u00e1cu a my po\u017eiadame n\u00e1\u0161 t\u00edm, aby va\u0161u \u00fa\u017easn\u00fa pr\u00e1cu vyzdvihol grafick\u00fdm abstraktom! Po\u010fme robi\u0165 vedu. <\/p>\n\n\n\n

<\/p>\n\n\n\n

<\/div>\n\n\n\n

<\/p>","protected":false},"excerpt":{"rendered":"

Uveden\u00fd \u010dl\u00e1nok hovor\u00ed o r\u00f4znych srdcov\u00fdch komplik\u00e1ci\u00e1ch sp\u00f4soben\u00fdch COVID-19 po\u010das infek\u010dn\u00e9ho cyklu a o jeho dlhodob\u00fdch \u00fa\u010dinkoch. <\/p>","protected":false},"author":4,"featured_media":16097,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[419,956],"tags":[870,96,554,964],"yoast_head":"\nIs it COVID or the effect of vaccination? Cardiovascular emergencies<\/title>\n<meta name=\"description\" content=\"The featured article talks about various cardia complications caused by COVID-19 during its infection cycle and its long-term effects.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mindthegraph.com\/blog\/sk\/covid-alebo-ucinok-ockovania\/\" \/>\n<meta property=\"og:locale\" content=\"sk_SK\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Is it COVID or the effect of vaccination? 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He has a Ph.D. and solid scientific background in Psychopharmacology and experience as a Guest Researcher at the Max Planck Institute of Psychiatry (Germany) and Researcher in D'Or Institute for Research and Education (IDOR, Brazil). Fabricio holds over 2500 citations in Google Scholar. He has 10 years of experience in small innovative businesses, with relevant experience in product design and innovation management. Connect with him on LinkedIn - Fabricio Pamplona.","sameAs":["http:\/\/mindthegraph.com","https:\/\/www.linkedin.com\/in\/fabriciopamplona"],"url":"https:\/\/mindthegraph.com\/blog\/sk\/author\/fabricio\/"}]}},"_links":{"self":[{"href":"https:\/\/mindthegraph.com\/blog\/sk\/wp-json\/wp\/v2\/posts\/16092"}],"collection":[{"href":"https:\/\/mindthegraph.com\/blog\/sk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mindthegraph.com\/blog\/sk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/sk\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/sk\/wp-json\/wp\/v2\/comments?post=16092"}],"version-history":[{"count":7,"href":"https:\/\/mindthegraph.com\/blog\/sk\/wp-json\/wp\/v2\/posts\/16092\/revisions"}],"predecessor-version":[{"id":16116,"href":"https:\/\/mindthegraph.com\/blog\/sk\/wp-json\/wp\/v2\/posts\/16092\/revisions\/16116"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/sk\/wp-json\/wp\/v2\/media\/16097"}],"wp:attachment":[{"href":"https:\/\/mindthegraph.com\/blog\/sk\/wp-json\/wp\/v2\/media?parent=16092"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/sk\/wp-json\/wp\/v2\/categories?post=16092"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/sk\/wp-json\/wp\/v2\/tags?post=16092"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}