{"id":13008,"date":"2021-06-21T18:09:00","date_gmt":"2021-06-21T21:09:00","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=13008"},"modified":"2023-01-05T14:38:06","modified_gmt":"2023-01-05T17:38:06","slug":"napping-time-genetics","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/sk\/napping-time-genetics\/","title":{"rendered":"Genetika \u010dasu na sp\u00e1nok: Ako m\u00f4\u017ee zdriemnutie ovplyvni\u0165 genetick\u00fa variabilitu"},"content":{"rendered":"

\u010cas na zdriemnutie po\u010das d\u0148a je pre v\u00e4\u010d\u0161inu \u013eud\u00ed vinn\u00fdm pote\u0161en\u00edm.<\/p>\n\n\n

\n
\"Garfield<\/a><\/figure><\/div>\n\n\n

V\u00e4\u010d\u0161inou je to tie\u017e zvyk, ktor\u00fd sa v\u017eil do ka\u017edodennej rutiny. Je to ve\u013emi be\u017en\u00e9 u mnoh\u00fdch druhov od m\u00fach a\u017e po cicavce.<\/p>\n\n\n\n

Zdriemnutie sa sp\u00e1ja aj so zlep\u0161en\u00edm bdelosti, \u010do je d\u00f4le\u017eit\u00e9 pre t\u00fdch, ktor\u00ed pracuj\u00fa neskoro v noci, alebo pre t\u00fdch, ktor\u00ed s\u00fa zvy\u010dajne nevyspat\u00ed.<\/p>\n\n\n\n

Hovor\u00ed sa tie\u017e, \u017ee prispieva k zv\u00fd\u0161eniu v\u00fdkonnosti, pam\u00e4ti a zmier\u0148uje stres. <\/p>\n\n\n\n

Okrem t\u00fdchto v\u00fdhod by v\u0161ak dlhodob\u00e9 n\u00e1sledky zdriemnutia mohli by\u0165 chronick\u00e9 pre pohodu jednotlivca.<\/p>\n\n\n\n

Hoci ide o kontroverzn\u00fa t\u00e9mu a d\u00f4vodom m\u00f4\u017ee by\u0165 viacero faktorov spojen\u00fdch s doj\u010den\u00edm, ako napr\u00edklad nedostato\u010dn\u00fd sp\u00e1nkov\u00fd cyklus, zl\u00e1 strava alebo zl\u00fd zdravotn\u00fd stav.<\/p>\n\n\n\n

Je \u010das sp\u00e1nku po\u010das d\u0148a va\u0161ou \u0161\u0165astnou hodinou? V\u00fdskumn\u00edci tvrdia nie\u010do in\u00e9. <\/strong><\/p>\n\n\n\n

Skupina v\u00fdskumn\u00edkov analyzovala \u00fa\u010dinky zdriemnutia prostredn\u00edctvom genetick\u00fdch zmien.<\/p>\n\n\n\n

Ich \u0161t\u00fadia spo\u010d\u00edvala v pochopen\u00ed genetickej variability r\u00f4znych jedincov prostredn\u00edctvom ich preferenci\u00ed pre d\u013a\u017eku a preferencie zdriemnutia.<\/p>\n\n\n\n

V s\u00fa\u010dasnosti sa v r\u00e1mci celogenomovej asocia\u010dnej \u0161t\u00fadie objavilo pribli\u017ene sedem genetick\u00fdch lokusov, ktor\u00e9 zodpovedaj\u00fa \u010dasu sp\u00e1nku po\u010das d\u0148a.<\/p>\n\n\n\n

V\u00fdskumn\u00edci pou\u017eili \u00fa\u010dastn\u00edkov britskej Biobanky eur\u00f3pskeho p\u00f4vodu (n=452 633), z ktor\u00fdch pribli\u017ene 38,2% si niekedy zdriemlo a 5,3% \u00fa\u010dastn\u00edkov si v\u017edy zdriemlo po\u010das d\u0148a.<\/p>\n\n\n\n

Takmer v\u017edy si zdriemli star\u0161\u00ed mu\u017ei s vysok\u00fdm BMI alebo indexom telesnej hmotnosti, boli im diagnostikovan\u00e9 poruchy sp\u00e1nku, faj\u010diari alebo d\u00f4chodcovia. Vykonali celogenomov\u00fa asocia\u010dn\u00fa \u0161t\u00fadiu (GWAS) s vysokokvalitn\u00fdmi priraden\u00fdmi genetick\u00fdmi variantmi, ktor\u00e1 zah\u0155\u0148ala pribli\u017ene \u0161tyri jazer\u00e1 \u00fa\u010dastn\u00edkov. To sa uskuto\u010dnilo zmenou r\u00f4znych predt\u00fdm zisten\u00fdch faktorov.<\/p>\n\n\n\n

\u00daspe\u0161ne identifikovali 123 genetick\u00fdch lokusov spolu s dedi\u010dnos\u0165ou zalo\u017eenou na jednonukleotidovom polymorfizme, ktor\u00e1 bola pribli\u017ene 11,9%.<\/p>\n\n\n\n

Svoju anal\u00fdzu GWAS z\u00fa\u017eili na osoby s vy\u0161\u0161\u00edm BMI. <\/p>\n\n\n\n

Zistilo sa, \u017ee zo 123 lokusov bolo 110 zadr\u017ean\u00fdch v celom gen\u00f3me.<\/p>\n\n\n\n

Analyzovali tie\u017e rozdielnos\u0165 vzorcov sp\u00e1nku u r\u00f4znych pohlav\u00ed v s\u00favislosti s chromoz\u00f3mom X. <\/p>\n\n\n\n

Okrem toho dospeli aj k z\u00e1veru, \u017ee g\u00e9ny s\u00fa zodpovedn\u00e9 za cestu hypersomnolencie pri obezite: PNOC (prepronocicept\u00edn), <\/em>a PATJ (zlo\u017eka polarity drobiv\u00fdch buniek).<\/em><\/p>\n\n\n\n

Okrem toho expresia g\u00e9nu FADS1 (desatur\u00e1za mastn\u00fdch kysel\u00edn), ktor\u00fd bol kolonizovan\u00fd, pouk\u00e1zala na pleiotropn\u00fd \u00fa\u010dinok metabolizmu lipidov na sp\u00e1nkov\u00fd re\u017eim.<\/p>\n\n\n\n

\u010eal\u0161ie korel\u00e1cie sa vn\u00edmali v s\u00favislosti s genetick\u00fdm gen\u00f3mom spolu so znakmi, ako je glykemick\u00fd index, antropometrick\u00e9 a kardiometabolick\u00e9 vlastnosti, z ktor\u00fdch sa mnoh\u00e9 korel\u00e1cie zn\u00ed\u017eili po zoh\u013eadnen\u00ed BMI. <\/p>\n\n\n\n

A \u010do viac, je to, \u017ee sk\u00f3re analyzovan\u00e9 fen\u00f3movou asoci\u00e1ciou vyu\u017e\u00edvaj\u00facou celodenn\u00fd sp\u00e1nok v celom gen\u00f3me pomohlo ku korel\u00e1cii chor\u00f4b s\u00favisiacich s obezitou, hypertenziou a predov\u0161etk\u00fdm s niektor\u00fdmi kardiometabolick\u00fdmi ochoreniami. <\/p>\n\n\n\n

Na z\u00e1ver mo\u017eno poveda\u0165, \u017ee ich zistenia otv\u00e1raj\u00fa o\u010di. Niekedy pr\u00e1ve tak\u00e9to n\u00e1vyky ved\u00fa k viacer\u00fdm ne\u017eiaducim komplik\u00e1ci\u00e1m v na\u0161om tele. \u010clovek mus\u00ed dodr\u017eiava\u0165 zdrav\u00fd re\u017eim a spr\u00e1vnu \u017eivotospr\u00e1vu. <\/p>\n\n\n

\n
\"mu\u017e<\/a><\/figure><\/div>\n\n\n

Ak sa chcete dozvedie\u0165 viac o ich v\u00fdskume, pozrite si odkaz uveden\u00fd ni\u017e\u0161ie.<\/p>\n\n\n\n

Dashti, H.S., Daghlas, I., Lane, J.M. et al.<\/em> Genetick\u00e9 determinanty denn\u00e9ho sp\u00e1nku a vplyv na kardiometabolick\u00e9 zdravie. Nat Commun<\/em> 12, 900 (2021). DOI : https:\/\/doi.org\/10.1038\/s41467-020-20585-3<\/a><\/p>\n\n\n\n

V gal\u00e9rii Mind the Graph n\u00e1jdete mnoho ilustr\u00e1ci\u00ed t\u00fdkaj\u00facich sa genetiky. Kliknite na obr\u00e1zok ni\u017e\u0161ie a pozrite si ho.<\/p>\n\n\n

\n
\"\"\/<\/a><\/figure><\/div>","protected":false},"excerpt":{"rendered":"

\u010cas na zdriemnutie po\u010das d\u0148a je pre v\u00e4\u010d\u0161inu \u013eud\u00ed vinn\u00fdm pote\u0161en\u00edm. V\u00e4\u010d\u0161inou je to tie\u017e zvyk, ktor\u00fd sa v\u017eil do ka\u017edodennej rutiny. Je ve\u013emi be\u017en\u00fd u mnoh\u00fdch druhov od m\u00fach a\u017e po cicavce. Zdriemnutie sa sp\u00e1ja aj so zlep\u0161en\u00edm bdelosti, \u010do je nevyhnutn\u00e9 pre t\u00fdch, ktor\u00ed pracuj\u00fa dlho do noci, alebo pre t\u00fdch, ktor\u00ed s\u00fa [...]<\/p>","protected":false},"author":18,"featured_media":13012,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[959,28],"tags":[554],"yoast_head":"\nDid you know that taking that nap can influence genetic - MTG<\/title>\n<meta name=\"description\" content=\"Is napping time your happy hour? Researchers analyzed the effects of napping through genetics variation.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mindthegraph.com\/blog\/sk\/dremez-genetika\/\" \/>\n<meta property=\"og:locale\" content=\"sk_SK\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Napping Time Genetics: How Taking a Nap Can Influence Genetic Variation\" \/>\n<meta property=\"og:description\" content=\"Is napping time your happy hour? Researchers analyzed the effects of napping through genetics variation.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/mindthegraph.com\/blog\/sk\/dremez-genetika\/\" \/>\n<meta property=\"og:site_name\" content=\"Mind the Graph Blog\" \/>\n<meta property=\"article:published_time\" content=\"2021-06-21T21:09:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-01-05T17:38:06+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2021\/06\/napping-time-genetics-img.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"628\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Bruna Soldera\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:title\" content=\"Napping Time Genetics: How Taking a Nap Can Influence Genetic Variation\" \/>\n<meta name=\"twitter:image\" content=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2021\/06\/napping-time-genetics-twitter.jpg\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Bruna Soldera\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Did you know that taking that nap can influence genetic - MTG","description":"Is napping time your happy hour? Researchers analyzed the effects of napping through genetics variation.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/mindthegraph.com\/blog\/sk\/dremez-genetika\/","og_locale":"sk_SK","og_type":"article","og_title":"Napping Time Genetics: How Taking a Nap Can Influence Genetic Variation","og_description":"Is napping time your happy hour? Researchers analyzed the effects of napping through genetics variation.","og_url":"https:\/\/mindthegraph.com\/blog\/sk\/dremez-genetika\/","og_site_name":"Mind the Graph Blog","article_published_time":"2021-06-21T21:09:00+00:00","article_modified_time":"2023-01-05T17:38:06+00:00","og_image":[{"width":1200,"height":628,"url":"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2021\/06\/napping-time-genetics-img.jpg","type":"image\/jpeg"}],"author":"Bruna Soldera","twitter_card":"summary_large_image","twitter_title":"Napping Time Genetics: How Taking a Nap Can Influence Genetic Variation","twitter_image":"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2021\/06\/napping-time-genetics-twitter.jpg","twitter_misc":{"Written by":"Bruna Soldera","Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/mindthegraph.com\/blog\/sl\/dremez-genetika\/","url":"https:\/\/mindthegraph.com\/blog\/sl\/dremez-genetika\/","name":"Did you know that taking that nap can influence genetic - MTG","isPartOf":{"@id":"https:\/\/mindthegraph.com\/blog\/#website"},"datePublished":"2021-06-21T21:09:00+00:00","dateModified":"2023-01-05T17:38:06+00:00","author":{"@id":"https:\/\/mindthegraph.com\/blog\/#\/schema\/person\/6a3f0be2cd19879e0b9b54457a069602"},"description":"Is napping time your happy hour? Researchers analyzed the effects of napping through genetics variation.","breadcrumb":{"@id":"https:\/\/mindthegraph.com\/blog\/sl\/dremez-genetika\/#breadcrumb"},"inLanguage":"sk-SK","potentialAction":[{"@type":"ReadAction","target":["https:\/\/mindthegraph.com\/blog\/sl\/dremez-genetika\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/mindthegraph.com\/blog\/sl\/dremez-genetika\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/mindthegraph.com\/blog\/"},{"@type":"ListItem","position":2,"name":"Napping Time Genetics: How Taking a Nap Can Influence Genetic Variation"}]},{"@type":"WebSite","@id":"https:\/\/mindthegraph.com\/blog\/#website","url":"https:\/\/mindthegraph.com\/blog\/","name":"Mind the Graph Blog","description":"Your science can be beautiful!","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/mindthegraph.com\/blog\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"sk-SK"},{"@type":"Person","@id":"https:\/\/mindthegraph.com\/blog\/#\/schema\/person\/6a3f0be2cd19879e0b9b54457a069602","name":"Bruna Soldera","image":{"@type":"ImageObject","inLanguage":"sk-SK","@id":"https:\/\/mindthegraph.com\/blog\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/93afc55eb938f215d2b7a23322de49be?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/93afc55eb938f215d2b7a23322de49be?s=96&d=mm&r=g","caption":"Bruna Soldera"},"sameAs":["http:\/\/mindthegraph.com","https:\/\/www.linkedin.com\/in\/bruna-soldera-826426126\/"],"url":"https:\/\/mindthegraph.com\/blog\/sk\/author\/bruna\/"}]}},"_links":{"self":[{"href":"https:\/\/mindthegraph.com\/blog\/sk\/wp-json\/wp\/v2\/posts\/13008"}],"collection":[{"href":"https:\/\/mindthegraph.com\/blog\/sk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mindthegraph.com\/blog\/sk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/sk\/wp-json\/wp\/v2\/users\/18"}],"replies":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/sk\/wp-json\/wp\/v2\/comments?post=13008"}],"version-history":[{"count":9,"href":"https:\/\/mindthegraph.com\/blog\/sk\/wp-json\/wp\/v2\/posts\/13008\/revisions"}],"predecessor-version":[{"id":26034,"href":"https:\/\/mindthegraph.com\/blog\/sk\/wp-json\/wp\/v2\/posts\/13008\/revisions\/26034"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/sk\/wp-json\/wp\/v2\/media\/13012"}],"wp:attachment":[{"href":"https:\/\/mindthegraph.com\/blog\/sk\/wp-json\/wp\/v2\/media?parent=13008"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/sk\/wp-json\/wp\/v2\/categories?post=13008"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/sk\/wp-json\/wp\/v2\/tags?post=13008"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}