{"id":9012,"date":"2019-06-03T11:07:17","date_gmt":"2019-06-03T14:07:17","guid":{"rendered":"https:\/\/blog.mindthegraph.com\/?p=9012"},"modified":"2022-10-18T08:23:58","modified_gmt":"2022-10-18T11:23:58","slug":"award-zika-virus-infection","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/ro\/premiu-zika-virus-infectie\/","title":{"rendered":"Virusul Zika: Studiul premiat care aduce o nou\u0103 lumin\u0103 asupra consecin\u021belor pe termen lung"},"content":{"rendered":"

Este \u00eentotdeauna uimitor s\u0103 ar\u0103t\u0103m munca \u0219tiin\u021bific\u0103 a utilizatorilor no\u0219tri. A\u0219adar, ast\u0103zi v\u0103 voi prezenta cercet\u0103toarea brazilian\u0103 Isis de Souza \u0219i munca ei cu virusul zika. Isis \u0219i colegii ei studiaz\u0103 impactul infec\u021biei cu virusul Zika la \u0219oareci la \u00eenceputul vie\u021bii. Ea este, de asemenea, un utilizator mind the graph, iar prezentarea c\u00e2\u0219tig\u0103toare are resurse vizuale de la Mind the graph. Nu am putea fi mai m\u00e2ndri de at\u00e2t.<\/p>\n

Ce este virusul zika?<\/strong><\/h3>\n

Virusul Zika apar\u021bine familiei Flaviviridae. Acest grup include mai mul\u021bi viru\u0219i patogeni. Cel mai cunoscut este virusul febrei galbene, virusul tip pentru aceast\u0103 familie \u0219i, de asemenea, motivul pentru numele familiei, deoarece cuv\u00e2ntul flavus \u00eenseamn\u0103 \"galben\" \u00een latin\u0103. Pe l\u00e2ng\u0103 acesta, al\u021bi flavivirus sunt virusul West Nile, virusul dengue \u0219i virusul encefalitei transmise de c\u0103pu\u0219e.<\/p>\n

Familia Flaviviridae are dimensiuni comune (40-65 nm) \u0219i \u00eenveli\u0219uri virale care le acoper\u0103 nucleocapsida icosaedric\u0103 protectoare. De asemenea, materialul genetic este ARN \u0219i apar la microscopul electronic.<\/p>\n

Infograficul de mai jos prezint\u0103 structura de baz\u0103 a virusului zika:<\/p>\n

\"previzualizare_90481\"<\/a><\/p>\n

 Zika se r\u0103sp\u00e2nde\u0219te \u00een principal prin intermediul femelei Stegomya aegypti<\/em> \u021b\u00e2n\u021bar, care are nevoie de s\u00e2nge pentru a depune ou\u0103. \u021a\u00e2n\u021barul este activ mai ales \u00een timpul zilei.<\/p>\n

Lucrarea c\u00e2\u0219tig\u0103toare<\/strong><\/h2>\n

Recent, mul\u021bi cercet\u0103tori studiaz\u0103 tulbur\u0103rile neurologice legate de expunerea congenital\u0103 la virusul zika (ZIKV).<\/p>\n

\u00cen plus, microcefalia congenital\u0103 este unul dintre cele mai importante efecte raportate la nou-n\u0103scu\u021bii infecta\u021bi cu ZIKV. Din acest motiv, eforturile de cercetare se concentreaz\u0103 pe \u00een\u021belegerea mecanismelor microcefaliei congenitale induse de ZIKV.<\/p>\n

Cu toate acestea, doar 1 p\u00e2n\u0103 la 13% din fetu\u0219ii expu\u0219i prezint\u0103 malforma\u021bii fizice la na\u0219tere. Pe l\u00e2ng\u0103 aceasta, lipsesc informa\u021biile despre consecin\u021bele pe termen lung ale unei infec\u021bii perinatale.<\/p>\n

Astfel, Isis de Souza \u0219i colegii ei au folosit \u0219oareci pentru a studia condi\u021biile comportamentale \u0219i neuropatologice \u0219i consecin\u021bele pe termen scurt \u0219i lung \u0219i public\u0103 rezultatele \u00eentr-o lucrare intitulat\u0103 Consecin\u021bele neurologice acute \u0219i cronice ale infec\u021biei cu virusul Zika la \u0219oareci la \u00eenceputul vie\u021bii.<\/strong><\/p>\n

La om, exist\u0103 numeroase afec\u021biuni clinice asociate cu expunerea la virusul zika care apar la luni sau ani dup\u0103 na\u0219tere. Astfel, chiar dac\u0103 bebelu\u0219ii nu se nasc cu microcefalie, ace\u0219tia pot prezenta deficien\u021be motorii, displazie cortical\u0103 legat\u0103 de convulsii \u0219i alte tulbur\u0103ri neurologice.<\/p>\n

Potrivit autorilor, ace\u0219tia \"au infectat \u0219oareci nou-n\u0103scu\u021bi de tip s\u0103lbatic \u00een mod sistemic cu ZIKV \u0219i au efectuat o urm\u0103rire pe termen lung a consecin\u021belor comportamentale, neuropatologice \u0219i moleculare ale infec\u021biei. Raport\u0103m complica\u021bii pe termen scurt \u0219i lung dup\u0103 infec\u021bia cu ZIKV la \u0219oareci \u0219i ar\u0103t\u0103m c\u0103 neutralizarea timpurie a factorului de necroz\u0103 tumoral\u0103-\u03b1 (TNF-\u03b1) previne par\u021bial aceste efecte d\u0103un\u0103toare. Descoperirile noastre dezv\u0103luie necesitatea unei aten\u021bii speciale pentru o poten\u021bial\u0103 povar\u0103 a complica\u021biilor neuropatologice la copii \u0219i adolescen\u021bi dup\u0103 expunerea congenital\u0103 la ZIKV \u0219i sugereaz\u0103 c\u0103 inhibarea timpurie a neuroinflam\u0103rii poate fi un tratament poten\u021bial pentru a preveni sechelele neurologice pe termen lung la copiii infecta\u021bi cu ZIKV.\"<\/em><\/p>\n

 Premiul promovat de GE Healthcare Life Sciences<\/strong><\/h2>\n

Premiul \"Pr\u00eamio Jovem Talento em Ci\u00eancias da Vida\" sau Premiul pentru tinere talente \u00een domeniul \u0219tiin\u021belor vie\u021bii este promovat de Societatea brazilian\u0103 de biochimie \u0219i biologie molecular\u0103 \u0219i de GE Healthcare Life Sciences. Un comitet \u0219tiin\u021bific a ales cinci candida\u021bi care \u00ee\u0219i vor prezenta lucr\u0103rile \u00een cadrul Congresului anual, un eveniment care pune \u00een leg\u0103tur\u0103 profesori \u0219i studen\u021bi din \u00eentreaga Americ\u0103 Latin\u0103.<\/p>\n

Comitetul a selectat-o pe Isis de Oliveira, care \u0219i-a prezentat studiul privind consecin\u021bele expunerii la virusul zika.<\/p>\n

\"prezentare
Isis de Oliveira \u00ee\u0219i prezint\u0103 rezultatele<\/figcaption><\/figure>\n

Ea a scris o postare \u00een care a mul\u021bumit universit\u0103\u021bii sale \u0219i bursei care i-a permis studiile. \u00cen plus, ea \u0219i-a exprimat speran\u021ba c\u0103 genera\u021bia viitoare va avea oportunit\u0103\u021bile de a urma o carier\u0103 \u0219tiin\u021bific\u0103, a\u0219a cum a avut ea.<\/p>\n

A\u0219adar, dorim s\u0103 o felicit\u0103m pe Isis pentru munca ei extraordinar\u0103! Sper ca prin munca ei s\u0103 inspire mai mul\u021bi oameni s\u0103 devin\u0103 oameni de \u0219tiin\u021b\u0103.<\/p>\n

Iar dac\u0103 dori\u021bi s\u0103 v\u0103 face\u021bi datele mai vizuale pentru a comunica mai bine \u00een domeniul \u0219tiin\u021bific, pute\u021bi \u00eencerca Mind the Graph:<\/p>\n

\"\u021bine\u021bi<\/a><\/p>","protected":false},"excerpt":{"rendered":"

Este \u00eentotdeauna uimitor s\u0103 ar\u0103t\u0103m munca \u0219tiin\u021bific\u0103 a utilizatorilor no\u0219tri. A\u0219adar, ast\u0103zi v\u0103 voi prezenta cercet\u0103toarea brazilian\u0103 Isis de Souza \u0219i munca ei cu virusul zika. Isis \u0219i colegii ei studiaz\u0103 impactul infec\u021biei cu virusul Zika la \u0219oareci la \u00eenceputul vie\u021bii. Ea este, de asemenea, un utilizator mind the graph, iar prezentarea c\u00e2\u0219tig\u0103toare a [...]<\/p>","protected":false},"author":11,"featured_media":9080,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"image","meta":[],"categories":[40],"tags":[299,282,554,71,775,293,316,315],"yoast_head":"\nZika virus: the award-winning study that sheds light on the future<\/title>\n<meta name=\"description\" content=\"Microcephaly is a known effect related to congenital exposure to zika virus. 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