{"id":16651,"date":"2022-09-12T18:50:00","date_gmt":"2022-09-12T21:50:00","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=16651"},"modified":"2023-03-17T14:47:35","modified_gmt":"2023-03-17T17:47:35","slug":"success-case-immunotherapeutic-potential-of-crotoxin-anti-inflammatory-and-immunosuppressive-properties","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/pt\/sucesso-case-imunoterapeutico-potencial-de-crotoxina-anti-inflamatorio-e-imunosupressao-propriedades\/","title":{"rendered":"Potencial imunoterap\u00eautico da Crotoxina: propriedades anti-inflamat\u00f3rias e imunossupressoras Revis\u00e3o de Papel"},"content":{"rendered":"<p>Poderia ser um pouco dif\u00edcil explicar a modula\u00e7\u00e3o anti-inflamat\u00f3ria da crotoxina sem as imagens adequadas, mas \u00e9 por isso que o Mind the Graph existe!<\/p>\n\n\n\n<h2><strong>Uma revis\u00e3o da pesquisa cient\u00edfica sobre Crotoxin, um veneno da cascavel<\/strong><\/h2>\n\n\n\n<p>Em 'Immunotherapeutic potential of Crotoxin', Marco Sartim et al. (2018) observaram que nos \u00faltimos 80 anos, a Crotoxin se tornou uma das toxinas isoladas mais investigadas dos venenos de cobra. <\/p>\n\n\n\n<p>A crotoxina \u00e9 o principal componente t\u00f3xico no veneno da cascavel Crotalus durissus terrificus da Am\u00e9rica do Sul. Estudos demonstraram que o efeito imunomodulador da C.d.t. est\u00e1 associado \u00e0 produ\u00e7\u00e3o de mediadores anti-inflamat\u00f3rios. <\/p>\n\n\n\n<p>A capacidade da Crotoxina e de suas subunidades de modular o sistema imunol\u00f3gico introduziu novas perspectivas como agentes terap\u00eauticos potenciais.<\/p>\n\n\n\n<p><strong>Os pesquisadores revisaram 161 artigos.<\/strong><\/p>\n\n\n\n<p>Verifique o <a href=\"https:\/\/jvat.biomedcentral.com\/articles\/10.1186\/s40409-018-0178-3\" target=\"_blank\" rel=\"noreferrer noopener\">artigo original aqui<\/a>.<\/p>\n\n\n\n<h2><strong>Resumos gr\u00e1ficos alimentados por Mind the Graph<\/strong><\/h2>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html.webp\"><img decoding=\"async\" loading=\"lazy\" width=\"1024\" height=\"1003\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-1024x1003.webp\" alt=\"\" class=\"wp-image-20251\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-1024x1003.webp 1024w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-300x294.webp 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-768x752.webp 768w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-12x12.webp 12w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-100x98.webp 100w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html.webp 1418w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><figcaption class=\"wp-element-caption\"><em>Feito com <a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>O autor utilizou a plataforma Mind the Graph para criar uma figura esquem\u00e1tica sobre circula\u00e7\u00e3o, tecidos e eventos celulares modulados pela Crotoxin e suas subunidades durante o est\u00edmulo inflamat\u00f3rio.<\/p>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_Fig3_HTML.webp\"><img decoding=\"async\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_Fig3_HTML-839x1024.webp\" alt=\"\" class=\"wp-image-20252\"\/><\/a><figcaption class=\"wp-element-caption\"><em>Feito com <a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>O autor tamb\u00e9m detalhou a circula\u00e7\u00e3o sangu\u00ednea, a localiza\u00e7\u00e3o dos linf\u00f3citos e eventos celulares associados aos efeitos imunossupressores da Crotoxina e suas subunidades.<\/p>\n\n\n\n<p><strong>Este \u00e9 o poder dos infogr\u00e1ficos!<\/strong><\/p>\n\n\n\n<p>As conclus\u00f5es dos autores parecem consolidar os trabalhos anteriores nesta \u00e1rea: \"A Crotoxin foi capaz de suprimir a produ\u00e7\u00e3o espec\u00edfica de anticorpos anti-HSA IgG1 e IgG2a a partir de ratos imunizados com HAS, indicando sua capacidade de modular as respostas Th1 e Th2\", afirmou Sartim.<\/p>\n\n\n\n<h2><strong>Impacto e desempenho dos trabalhos<\/strong><\/h2>\n\n\n\n<p>Podemos analisar com <a href=\"https:\/\/mindthegraph.com\/blog\/altmetric\/\" target=\"_blank\" rel=\"noreferrer noopener\">Altmetric<\/a> dados que este documento tinha mais cita\u00e7\u00f5es <strong>do que <strong>84%<\/strong><\/strong> <strong>de outros artigos da Springer Nature.<\/strong><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1.png\"><img decoding=\"async\" loading=\"lazy\" width=\"322\" height=\"578\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1.png\" alt=\"\" class=\"wp-image-20254\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1.png 322w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1-167x300.png 167w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1-7x12.png 7w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1-56x100.png 56w\" sizes=\"(max-width: 322px) 100vw, 322px\" \/><\/a><figcaption class=\"wp-element-caption\"><em>Fonte <a href=\"https:\/\/citations.springernature.com\/item?doi=10.1186\/s40409-018-0178-3&amp;start=11&amp;years=&amp;journals=&amp;books=&amp;authors=\" target=\"_blank\" rel=\"noreferrer noopener\">Crossref<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>Use o poder dos infogr\u00e1ficos para impulsionar e <a href=\"https:\/\/mindthegraph.com\/blog\/research-journal-impact-factor\/\">impacte seu artigo<\/a> tamb\u00e9m. Experimente o Mind the Graph!<\/p>\n\n\n\n<div class=\"is-layout-flex wp-block-buttons\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-background wp-element-button\" href=\"https:\/\/mindthegraph.com\/app\/auth\/register?from_url=\/\" style=\"border-radius:100px;background-color:#dc1866\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Experimente Mind the Graph<\/strong><\/a><\/div>\n<\/div>\n\n\n\n<div style=\"height:46px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Poderia ser um pouco dif\u00edcil explicar a modula\u00e7\u00e3o anti-inflamat\u00f3ria da crotoxina sem as imagens adequadas, mas o Mind the Graph existe!<\/p>","protected":false},"author":29,"featured_media":20047,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[195,958,957,960,1],"tags":[96,554,963],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.9 - 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