{"id":16670,"date":"2022-09-16T19:40:00","date_gmt":"2022-09-16T22:40:00","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=16670"},"modified":"2023-03-17T14:47:16","modified_gmt":"2023-03-17T17:47:16","slug":"success-case-nuclear-receptors-in-liver-fibrosis","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/pl\/sukces-przypadek-receptorow-jadrowych-w-zwloknieniu-watroby\/","title":{"rendered":"Receptory j\u0105drowe w zw\u0142\u00f3knieniu w\u0105troby Przegl\u0105d artyku\u0142u"},"content":{"rendered":"

W tym przypadku autor wykorzysta\u0142 Mind the Graph do kompilacji danych liczbowych z r\u00f3\u017cnych \u017ar\u00f3de\u0142 w jednym miejscu. Opr\u00f3cz dok\u0142adnych ilustracji naukowych, nasz obszar roboczy ma przyjazny interfejs i jest bardzo \u0142atwy w u\u017cyciu.<\/p>\n\n\n\n

Sprawd\u017a ca\u0142o\u015b\u0107 artyku\u0142 oryginalny<\/a>. <\/p>\n\n\n\n

Rola receptor\u00f3w j\u0105drowych w zw\u0142\u00f3knieniu w\u0105troby<\/strong><\/h2>\n\n\n\n

Philipp K\u00f6nigshofer i wsp. (2021) donosz\u0105, \u017ce receptory j\u0105drowe s\u0105 aktywowanymi ligandami czynnikami transkrypcyjnymi, kt\u00f3re reguluj\u0105 ekspresj\u0119 gen\u00f3w r\u00f3\u017cnych kluczowych sygna\u0142\u00f3w molekularnych zaanga\u017cowanych w zw\u0142\u00f3knienie w\u0105troby. <\/p>\n\n\n\n

G\u0142\u00f3wnym kom\u00f3rkowym czynnikiem powoduj\u0105cym fibrogenez\u0119 w\u0105troby s\u0105 aktywowane w\u0105trobowe kom\u00f3rki gwia\u017adziste. R\u00f3\u017cne receptory j\u0105drowe reguluj\u0105 w\u0105trobow\u0105 ekspresj\u0119 cytokin prozapalnych i prozw\u0142\u00f3knieniowych.<\/p>\n\n\n\n

Abstrakcje graficzne obs\u0142ugiwane przez Mind the Graph<\/strong> w tym artykule<\/strong><\/h2>\n\n\n\n
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Wykonane z Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n
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Pierwszy rysunek przedstawia przegl\u0105d i klasyfikacj\u0119 receptor\u00f3w j\u0105drowych wed\u0142ug podrodzin.<\/p>\n\n\n\n

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Wykonane z Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n

Powy\u017cej widzimy r\u00f3\u017cne typy funkcji efektorowych receptor\u00f3w j\u0105drowych.<\/p>\n\n\n\n

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Wykonane z Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n

Na trzecim rysunku mo\u017cemy sprawdzi\u0107 przegl\u0105d zg\u0142oszonych efekt\u00f3w modulacji NR jako potencjalnych podej\u015b\u0107 terapeutycznych przeciwko chorobom w\u0105troby. <\/p>\n\n\n\n

Strza\u0142ki wskazuj\u0105 przypuszczalne korzystne dzia\u0142anie w chorobach w\u0105troby poprzez w g\u00f3r\u0119- (ciemnozielony)<\/strong><\/span> lub w d\u00f3\u0142- (jasnozielony)<\/span><\/strong> regulacja okre\u015blonych mechanizm\u00f3w, kt\u00f3re wed\u0142ug doniesie\u0144 wspieraj\u0105 regresj\u0119 zw\u0142\u00f3knienia w\u0105troby lub zmniejszaj\u0105 zw\u0142\u00f3knienie w\u0105troby. <\/p>\n\n\n\n

Pomara\u0144czowe strza\u0142ki<\/mark><\/strong> wskazuj\u0105 na efekty i mechanizmy modulacji NR, kt\u00f3re s\u0105 kontrowersyjne lub jeszcze niewystarczaj\u0105co ocenione.<\/p>\n\n\n\n

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Wykonane z Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n

Ostatni rysunek przedstawia efekty molekularne modulator\u00f3w NR jako potencjalnego leczenia zw\u0142\u00f3knienia w\u0105troby, kt\u00f3re wed\u0142ug doniesie\u0144 wyst\u0119puj\u0105 g\u0142\u00f3wnie w HSC.<\/p>\n\n\n\n

K\u00f6nigshofer i wsp\u00f3\u0142pracownicy sugeruj\u0105, \u017ce dalsze badania nad sygnalizacj\u0105 zwi\u0105zan\u0105 z receptorami j\u0105drowymi mog\u0105 prowadzi\u0107 do rozwoju klinicznego skutecznych terapii przeciww\u0142\u00f3knieniowych dla pacjent\u00f3w z chorobami w\u0105troby.<\/p>\n\n\n\n

Dokumenty Wp\u0142yw i wydajno\u015b\u0107<\/strong><\/h2>\n\n\n\n

Wybieraj\u0105c roczn\u0105 opcj\u0119 por\u00f3wnania metryk z innymi artyku\u0142ami\/recenzjami, kt\u00f3re r\u00f3wnie\u017c zosta\u0142y opublikowane w tym samym roku kalendarzowym w tym czasopi\u015bmie, mo\u017cemy zauwa\u017cy\u0107, \u017ce Ten artyku\u0142 by\u0142 cytowany cz\u0119\u015bciej ni\u017c 57% z nich<\/strong>.<\/p>\n\n\n

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\u0179r\u00f3d\u0142o PlumX<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n

Wykorzystaj moc infografiki, aby wzmocni\u0107 sw\u00f3j artyku\u0142. Wypr\u00f3buj Mind the Graph!<\/p>\n\n\n\n

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Wypr\u00f3buj Mind the Graph<\/strong><\/a><\/div>\n<\/div>\n\n\n\n
<\/div>","protected":false},"excerpt":{"rendered":"

Ten artyku\u0142 zawiera ilustracje naukowe wykonane za pomoc\u0105 Mind the Graph w celu przedstawienia receptor\u00f3w j\u0105drowych w zw\u0142\u00f3knieniu w\u0105troby.<\/p>","protected":false},"author":29,"featured_media":20044,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[195,958,957,960,1],"tags":[96,554,775,963],"yoast_head":"\nNuclear receptors in liver fibrosis Paper Review - Mind the Graph Blog<\/title>\n<meta name=\"description\" content=\"This article has scientific illustrations made with Mind the Graph to represent nuclear receptors in liver fibrosis.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mindthegraph.com\/blog\/pl\/sukces-przypadek-receptorow-jadrowych-w-zwloknieniu-watroby\/\" \/>\n<meta property=\"og:locale\" content=\"pl_PL\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Nuclear receptors in liver fibrosis Paper Review - Mind the Graph Blog\" \/>\n<meta property=\"og:description\" content=\"This article has scientific illustrations made with Mind the Graph to represent nuclear receptors in liver fibrosis.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/mindthegraph.com\/blog\/pl\/sukces-przypadek-receptorow-jadrowych-w-zwloknieniu-watroby\/\" \/>\n<meta property=\"og:site_name\" content=\"Mind the Graph Blog\" \/>\n<meta property=\"article:published_time\" content=\"2022-09-16T22:40:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-03-17T17:47:16+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/blog_7.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1125\" \/>\n\t<meta property=\"og:image:height\" content=\"614\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Artur Zignani\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:image\" content=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/blog_7.jpg\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Artur Zignani\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Nuclear receptors in liver fibrosis Paper Review - 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