{"id":16662,"date":"2022-09-22T19:23:00","date_gmt":"2022-09-22T22:23:00","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=16662"},"modified":"2023-03-17T14:46:01","modified_gmt":"2023-03-17T17:46:01","slug":"success-case-nmda-receptor-adjusted-co-administration-of-ecstasy-and-cannabinoid-receptor-1-agonist","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/pl\/sukces-przypadek-nmda-receptor-adjusted-co-administration-of-ecstasy-and-cannabinoid-receptor-1-agonist\/","title":{"rendered":"Regulacja receptora NMDA przy jednoczesnym podawaniu ecstasy i agonisty receptora kannabinoidowego-1 w ciele migda\u0142owatym poprzez stymulacj\u0119 szlaku BDNF\/Trk-B\/CREB u doros\u0142ych samc\u00f3w szczur\u00f3w Przegl\u0105d publikacji"},"content":{"rendered":"<p>Graficzne streszczenia staj\u0105 si\u0119 bardzo popularne w\u015br\u00f3d naukowc\u00f3w. Oznacza to, \u017ce autor stworzy\u0142 jeden niesamowity projekt, aby wyja\u015bni\u0107 ca\u0142y sens tego artyku\u0142u za pomoc\u0105 dok\u0142adnych obraz\u00f3w.<\/p>\n\n\n\n<p>Sprawd\u017a ca\u0142o\u015b\u0107 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0361923016303756\" target=\"_blank\" rel=\"noreferrer noopener\">artyku\u0142 oryginalny<\/a>.<\/p>\n\n\n\n<h2><strong>Spo\u017cycie selektywnego agonisty CB-1, takiego jak ACPA, chroni neurony przed toksyczno\u015bci\u0105 MDMA w ciele migda\u0142owatym.<\/strong><\/h2>\n\n\n\n<p>W artykule \"NMDA receptor adjusted co-administration of ecstasy and cannabinoid receptor-1 agonist in the amygdala via stimulation of BDNF\/Trk-B\/CREB pathway in adult male rats\", Ashabi i wsp\u00f3\u0142pracownicy (2017) zauwa\u017cyli, \u017ce blokada NMDA zmniejszy\u0142a szybko\u015b\u0107 wypalania neuron\u00f3w i poziom bia\u0142ka wi\u0105\u017c\u0105cego czynnik neurotroficzny pochodz\u0105cy z kinazy tyrozynowej B\/czynnika neurotroficznego pochodz\u0105cego z m\u00f3zgu\/cAMP u szczur\u00f3w, kt\u00f3rym jednocze\u015bnie wstrzykni\u0119to MDMA i agonist\u0119 receptora CB1. <\/p>\n\n\n\n<p>Uk\u0142ad glutaminergiczny reguluje ochronn\u0105 rol\u0119 kombinacji MDMA i ACPA poprzez receptory TrK-B.<\/p>\n\n\n\n<h2><strong>Abstrakcje graficzne obs\u0142ugiwane przez Mind the Graph<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" loading=\"lazy\" width=\"835\" height=\"305\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264.png\" alt=\"\" class=\"wp-image-20094\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264.png 835w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264-300x110.png 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264-768x281.png 768w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264-18x7.png 18w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080749264-100x37.png 100w\" sizes=\"(max-width: 835px) 100vw, 835px\" \/><figcaption class=\"wp-element-caption\"><em>Wykonane z&nbsp;<a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure>\n\n\n\n<p>Aktywacja receptora CB1 lub indukcja MDMA zmniejsza\u0142a szybko\u015b\u0107 odpalania neuron\u00f3w. Jednoczesne wstrzykni\u0119cie tych dw\u00f3ch lek\u00f3w zwi\u0119kszy\u0142o prze\u017cywalno\u015b\u0107 kom\u00f3rek neuronalnych, a zdarzenia te zosta\u0142y odwr\u00f3cone przez antagonist\u0119 receptor\u00f3w NMDA. <\/p>\n\n\n\n<p>Prawdopodobnie ochronna rola receptor\u00f3w glutaminergicznych mo\u017ce wynika\u0107 z aktywacji szlak\u00f3w BDNF\/Trk-B. <\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" loading=\"lazy\" width=\"718\" height=\"512\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785.png\" alt=\"\" class=\"wp-image-20093\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785.png 718w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785-300x214.png 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785-18x12.png 18w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/image_2022-08-09_080828785-100x71.png 100w\" sizes=\"(max-width: 718px) 100vw, 718px\" \/><figcaption class=\"wp-element-caption\"><em>Wykonane z&nbsp;<a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure>\n\n\n\n<h2><strong>Dokumenty Wp\u0142yw i wydajno\u015b\u0107<\/strong><\/h2>\n\n\n\n<p>Wybieraj\u0105c roczn\u0105 opcj\u0119 por\u00f3wnania metryk z innymi artyku\u0142ami\/recenzjami, kt\u00f3re r\u00f3wnie\u017c zosta\u0142y opublikowane w tym samym roku kalendarzowym w tym czasopi\u015bmie, mo\u017cemy zauwa\u017cy\u0107, \u017ce <strong>Ten artyku\u0142 by\u0142 cytowany cz\u0119\u015bciej ni\u017c 47% z nich<\/strong>.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" loading=\"lazy\" width=\"377\" height=\"330\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1.png\" alt=\"\" class=\"wp-image-20096\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1.png 377w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1-300x263.png 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1-14x12.png 14w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/ndma-metrics-1-100x88.png 100w\" sizes=\"(max-width: 377px) 100vw, 377px\" \/><\/figure>\n\n\n\n<p>Wykorzystaj moc infografiki, aby wzmocni\u0107 sw\u00f3j artyku\u0142. Wypr\u00f3buj Mind the Graph!<\/p>","protected":false},"excerpt":{"rendered":"<p>Ucz si\u0119 z tymi, kt\u00f3rzy ju\u017c odkryli moc infografik. Ten artyku\u0142 zawiera graficzne streszczenia wykonane za pomoc\u0105 Mind the Graph. <\/p>","protected":false},"author":29,"featured_media":20081,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[195,958,957,960,1],"tags":[96,963],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>NMDA receptor adjusted co-administration of ecstasy and cannabinoid receptor-1 agonist in the amygdala via stimulation of BDNF\/Trk-B\/CREB pathway in adult male rats Paper Review - Mind the Graph Blog<\/title>\n<meta name=\"description\" content=\"Learn with the ones who already discovered the power of infographics. 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