{"id":16651,"date":"2022-09-12T18:50:00","date_gmt":"2022-09-12T21:50:00","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=16651"},"modified":"2023-03-17T14:47:35","modified_gmt":"2023-03-17T17:47:35","slug":"success-case-immunotherapeutic-potential-of-crotoxin-anti-inflammatory-and-immunosuppressive-properties","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/pl\/success-case-immunotherapeutic-potential-of-crotoxin-anti-inflammatory-and-immunosuppressive-properties\/","title":{"rendered":"Immunoterapeutyczny potencja\u0142 kroptoksyny: w\u0142a\u015bciwo\u015bci przeciwzapalne i immunosupresyjne Paper Review"},"content":{"rendered":"<p>Wyja\u015bnienie modulacji przeciwzapalnej kroptoksyny bez odpowiednich obraz\u00f3w mo\u017ce by\u0107 nieco trudne, ale w\u0142a\u015bnie dlatego istnieje Mind the Graph!<\/p>\n\n\n\n<h2><strong>Przegl\u0105d bada\u0144 naukowych nad kroptoksyn\u0105, jadem grzechotnika<\/strong><\/h2>\n\n\n\n<p>W artykule \"Immunotherapeutic potential of Crotoxin\", Marco Sartim et al. (2018) zauwa\u017cyli, \u017ce przez ostatnie 80 lat kroptoksyna sta\u0142a si\u0119 jedn\u0105 z najcz\u0119\u015bciej badanych toksyn izolowanych z jad\u00f3w w\u0119\u017cy. <\/p>\n\n\n\n<p>Krotoksyna jest g\u0142\u00f3wnym toksycznym sk\u0142adnikiem jadu po\u0142udniowoameryka\u0144skiego grzechotnika Crotalus durissus terrificus. Badania wykaza\u0142y, \u017ce dzia\u0142anie immunomoduluj\u0105ce C.d.t. jest zwi\u0105zane z produkcj\u0105 mediator\u00f3w przeciwzapalnych. <\/p>\n\n\n\n<p>Zdolno\u015b\u0107 kroptoksyny i jej podjednostek do modulowania uk\u0142adu odporno\u015bciowego wprowadzi\u0142a nowe perspektywy jako potencjalnych \u015brodk\u00f3w terapeutycznych.<\/p>\n\n\n\n<p><strong>Naukowcy dokonali przegl\u0105du 161 artyku\u0142\u00f3w.<\/strong><\/p>\n\n\n\n<p>Sprawd\u017a <a href=\"https:\/\/jvat.biomedcentral.com\/articles\/10.1186\/s40409-018-0178-3\" target=\"_blank\" rel=\"noreferrer noopener\">oryginalny artyku\u0142 tutaj<\/a>.<\/p>\n\n\n\n<h2><strong>Abstrakcje graficzne obs\u0142ugiwane przez Mind the Graph<\/strong><\/h2>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html.webp\"><img decoding=\"async\" loading=\"lazy\" width=\"1024\" height=\"1003\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-1024x1003.webp\" alt=\"\" class=\"wp-image-20251\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-1024x1003.webp 1024w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-300x294.webp 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-768x752.webp 768w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-12x12.webp 12w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-100x98.webp 100w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html.webp 1418w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><figcaption class=\"wp-element-caption\"><em>Wykonane z <a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>Autor wykorzysta\u0142 platform\u0119 Mind the Graph do stworzenia schematycznego rysunku kr\u0105\u017cenia, tkanek i zdarze\u0144 kom\u00f3rkowych modulowanych przez Crotoxin i jego podjednostki podczas bod\u017aca zapalnego.<\/p>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_Fig3_HTML.webp\"><img decoding=\"async\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_Fig3_HTML-839x1024.webp\" alt=\"\" class=\"wp-image-20252\"\/><\/a><figcaption class=\"wp-element-caption\"><em>Wykonane z <a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>Autor szczeg\u00f3\u0142owo opisa\u0142 r\u00f3wnie\u017c kr\u0105\u017cenie krwi, nap\u0142yw limfocyt\u00f3w do w\u0119z\u0142\u00f3w ch\u0142onnych i zdarzenia kom\u00f3rkowe zwi\u0105zane z immunosupresyjnym dzia\u0142aniem kroptoksyny i jej podjednostek.<\/p>\n\n\n\n<p><strong>Oto pot\u0119ga infografik!<\/strong><\/p>\n\n\n\n<p>Wnioski autor\u00f3w wydaj\u0105 si\u0119 konsolidowa\u0107 wcze\u015bniejsze prace w tej dziedzinie: \"Kroptoksyna by\u0142a w stanie t\u0142umi\u0107 produkcj\u0119 swoistych przeciwcia\u0142 IgG1 i IgG2a przeciwko HSA u myszy z immunizacj\u0105 HAS, co wskazuje na jej zdolno\u015b\u0107 do modulowania odpowiedzi Th1 i Th2\" - twierdzi Sartim.<\/p>\n\n\n\n<h2><strong>Dokumenty Wp\u0142yw i wydajno\u015b\u0107<\/strong><\/h2>\n\n\n\n<p>Mo\u017cemy analizowa\u0107 za pomoc\u0105 <a href=\"https:\/\/mindthegraph.com\/blog\/altmetric\/\" target=\"_blank\" rel=\"noreferrer noopener\">Altmetric<\/a> dane, \u017ce ten artyku\u0142 mia\u0142 wi\u0119cej cytowa\u0144 <strong>ni\u017c <strong>84%<\/strong><\/strong> <strong>innych artyku\u0142\u00f3w ze Springer Nature.<\/strong><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1.png\"><img decoding=\"async\" loading=\"lazy\" width=\"322\" height=\"578\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1.png\" alt=\"\" class=\"wp-image-20254\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1.png 322w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1-167x300.png 167w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1-7x12.png 7w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1-56x100.png 56w\" sizes=\"(max-width: 322px) 100vw, 322px\" \/><\/a><figcaption class=\"wp-element-caption\"><em>\u0179r\u00f3d\u0142o <a href=\"https:\/\/citations.springernature.com\/item?doi=10.1186\/s40409-018-0178-3&amp;start=11&amp;years=&amp;journals=&amp;books=&amp;authors=\" target=\"_blank\" rel=\"noreferrer noopener\">Crossref<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>Wykorzystaj moc infografik, aby zwi\u0119kszy\u0107 i <a href=\"https:\/\/mindthegraph.com\/blog\/research-journal-impact-factor\/\">wp\u0142yw na artyku\u0142<\/a> r\u00f3wnie\u017c. Wypr\u00f3buj Mind the Graph!<\/p>\n\n\n\n<div class=\"is-layout-flex wp-block-buttons\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-background wp-element-button\" href=\"https:\/\/mindthegraph.com\/app\/auth\/register?from_url=\/\" style=\"border-radius:100px;background-color:#dc1866\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Wypr\u00f3buj Mind the Graph<\/strong><\/a><\/div>\n<\/div>\n\n\n\n<div style=\"height:46px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Wyja\u015bnienie modulacji przeciwzapalnej kroptoksyny bez odpowiednich obraz\u00f3w mo\u017ce by\u0107 nieco trudne, ale Mind the Graph istnieje!<\/p>","protected":false},"author":29,"featured_media":20047,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[195,958,957,960,1],"tags":[96,554,963],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.9 - 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