{"id":7254,"date":"2017-06-21T17:35:04","date_gmt":"2017-06-21T20:35:04","guid":{"rendered":"https:\/\/blog.mindthegraph.com\/?p=7254"},"modified":"2022-10-18T08:29:23","modified_gmt":"2022-10-18T11:29:23","slug":"alzheimers-graphical-abstracts","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/nl\/alzheimers-graphical-abstracts\/","title":{"rendered":"Alzheimer's grafische samenvattingen: Wat er nieuw is in de neurowetenschappen op een visuele manier"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">We vinden het erg leuk om te laten zien wat onze gebruikers doen - vooral als ze papers publiceren met behulp van Mind the Graph illustraties en tools.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Dus, vandaag tonen we u het onderzoek van een premium gebruiker aan de geest de grafiek, <a href=\"https:\/\/www.researchgate.net\/profile\/Stefania_Forner3\">Stefania Forner<\/a>.  Haar overzichtsartikel werd onlangs gepubliceerd in Trends in Neurosciences onder de titel<\/span><b><a href=\"http:\/\/www.cell.com\/trends\/neurosciences\/fulltext\/S0166-2236(17)30069-3?rss=yes\"> Synaptische aantasting bij de ziekte van Alzheimer: Een ontregelde symfonie.<\/a> <\/b>\u00a0Ze maakte twee Alzheimer grafische abstracts om haar werk te illustreren.<\/p>\n<p style=\"text-align: justify;\"><span style=\"font-weight: 400;\"><strong>Laten we eerst beginnen met een kleine introductie van Stefania's studie...<\/strong>:<\/span><\/p>\n<p><span style=\"font-weight: 400;\">De ziekte van Alzheimer (AD) is een neurodegeneratieve aandoening die cognitieve stoornissen en geheugenverlies veroorzaakt.  AD is de zesde belangrijkste doodsoorzaak in de VS en treft <strong>35 miljoen mensen<\/strong> over de hele wereld. <\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-weight: 400;\">Er zijn aanwijzingen dat er een oorzakelijk verband bestaat tussen de cognitieve stoornissen van AD en het verlies van synapsen. Ook kan synapsdisfunctie verband houden met twee pathologische routes. Een extracellulaire ophoping van <strong>beta-amylo\u00efde peptide<\/strong> en intracellulaire accumulatie van <strong>tau-eiwit<\/strong>.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-weight: 400;\">Het is bekend dat deze twee processen een belangrijke rol spelen bij AD. Een van de belangrijkste fundamentele vragen die echter blijven bestaan, heeft betrekking op de moleculaire relatie tussen beta-amylo\u00efde en tau, en hoe deze twee spelers in onderlinge afhankelijkheid schade toebrengen aan de synaptische functie bij AD.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-weight: 400;\">Om de effecten van tau-eiwit en beta-amylo\u00efde peptide op de synaptische functie en AD afzonderlijk te analyseren, gebruikte Stefania twee grafische samenvattingen die zij maakte op het Mind the Graph-platform. De ene toont de vorming van beta-amylo\u00efde oligomeren en hun mechanismen van synaptische toxiciteit en de andere toont het verband tussen tau-eiwit en synapsen in neuronen. \u00a0<\/span><\/p>\n<h2 style=\"text-align: justify;\"><strong>Grafische samenvattingen van Alzheimer<\/strong><\/h2>\n<p><a href=\"https:\/\/blog.mindthegraph.com\/wp-content\/uploads\/2017\/06\/alzheimer-disorder.png\"><img decoding=\"async\" loading=\"lazy\" class=\"aligncenter wp-image-7255\" src=\"https:\/\/blog.mindthegraph.com\/wp-content\/uploads\/2017\/06\/alzheimer-disorder.png\" alt=\"Alzheimer aandoening\" width=\"580\" height=\"473\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2017\/06\/alzheimer-disorder.png 521w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2017\/06\/alzheimer-disorder-300x245.png 300w\" sizes=\"(max-width: 580px) 100vw, 580px\" \/><\/a><\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/blog.mindthegraph.com\/wp-content\/uploads\/2017\/06\/alzheimer-disorder-tau.png\"><img decoding=\"async\" loading=\"lazy\" class=\"aligncenter size-full wp-image-7256\" src=\"https:\/\/blog.mindthegraph.com\/wp-content\/uploads\/2017\/06\/alzheimer-disorder-tau.png\" alt=\"alzheimer-disorder-tau\" width=\"607\" height=\"609\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2017\/06\/alzheimer-disorder-tau.png 607w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2017\/06\/alzheimer-disorder-tau-150x150.png 150w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2017\/06\/alzheimer-disorder-tau-300x300.png 300w\" sizes=\"(max-width: 607px) 100vw, 607px\" \/><\/a><\/p>\n<p>&nbsp;<\/p>\n<blockquote>\n<p style=\"text-align: right;\">\"Met name studies die de moleculaire relatie tussen A\u03b2, tau en synaptische tekorten en\/of verlies onderzoeken, hebben licht geworpen op hoe deze pathologie\u00ebn uiteindelijk kunnen leiden tot cognitieve achteruitgang bij pati\u00ebnten. De identificatie van verschillende potenti\u00eble pre- en postsynaptische routes kan bijdragen tot de onderliggende klinische symptomen van AD.\"<\/p>\n<\/blockquote>\n<h2><\/h2>\n<p>&nbsp;<\/p>\n<h2><b>Ik wil ook grafische samenvattingen van mijn onderzoek!<\/b><\/h2>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">Grafische samenvattingen zijn een manier om hoofdpunten van je werk aan te vullen en te illustreren. Als je wilt leren hoe je zelf verbazingwekkende grafische samenvattingen kunt maken, zijn hier een paar berichten om je te helpen:<\/span><\/p>\n<ul>\n<li><a href=\"https:\/\/blog.mindthegraph.com\/graphical-abstracts-3-steps\/#.WUrD72grIdU\" target=\"_blank\" rel=\"noopener\">Grafische samenvattingen: Je bent 3 stappen verwijderd<\/a><\/li>\n<li><a href=\"https:\/\/blog.mindthegraph.com\/improvements\/#.WUrD9mgrIdU\" target=\"_blank\" rel=\"noopener\">Wij houden van upgrades: Elke dag verbeteren<\/a><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">U kunt Mind the Graph gratis gebruiken. We hebben een gratis versie waarin u het kunt proberen en toegang kunt krijgen tot onze wetenschappelijke bibliotheek. Premium gebruikers hebben volledige toegang tot het platform en speciale voordelen zoals u hier kunt zien.<\/span><\/p>\n<p><a href=\"https:\/\/blog.mindthegraph.com\/wp-content\/uploads\/2016\/10\/start_now.png\"><img decoding=\"async\" loading=\"lazy\" class=\"aligncenter wp-image-6373\" src=\"https:\/\/blog.mindthegraph.com\/wp-content\/uploads\/2016\/10\/start_now.png\" alt=\"infographic63724-3\" width=\"500\" height=\"200\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2016\/10\/start_now.png 1500w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2016\/10\/start_now-300x120.png 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2016\/10\/start_now-768x307.png 768w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2016\/10\/start_now-1024x410.png 1024w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/><\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>We vinden het erg leuk om onze gebruikers ongelooflijk werk te laten zien - vooral als ze papers publiceren met behulp van Mind the Graph illustraties en tools. Dus, vandaag tonen we u het onderzoek van een premium gebruiker bij de mind the graph, Stefania Forner.  Haar review artikel werd onlangs gepubliceerd in Trends in Neurosciences getiteld Synaptic impairment in Alzheimer [...]<\/p>","protected":false},"author":11,"featured_media":7269,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[956],"tags":[214,213,96,554,216,775,215],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Alzheimer&#039;s graphical abstracts: What&#039;s new in neuroscience in a visual way - Mind the Graph Blog<\/title>\n<meta name=\"description\" content=\"Today we\u2019ll show you the research of Stefania Forner. 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