{"id":26101,"date":"2023-01-06T14:55:00","date_gmt":"2023-01-06T17:55:00","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/publication-bias-copy\/"},"modified":"2023-01-12T17:14:12","modified_gmt":"2023-01-12T20:14:12","slug":"molecule-design","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/nb\/molekyl-design\/","title":{"rendered":"Hva er et molekyldesign, og hva er hensikten med det?"},"content":{"rendered":"

Den siste tiden har forst\u00e5elsen av celle- og molekyl\u00e6rbiologi \u00f8kt dramatisk. Med disse viktige oppdagelsene begynner vitenskapen \u00e5 gj\u00f8re fremskritt ved \u00e5 finne nye svar p\u00e5 gamle problemer.<\/p>\n\n\n\n

Et av disse vitenskapelige fremskrittene er molekyldesign. I denne artikkelen vil du l\u00e6re mer om molekyldesign og dets hovedform\u00e5l p\u00e5 en enkel og dynamisk m\u00e5te.<\/p>\n\n\n\n

Hva er et molekyl?<\/h2>\n\n\n\n

Et molekyl er en gruppe p\u00e5 to eller flere atomer som til sammen utgj\u00f8r den minste gjenkjennelige enheten som et rent materiale kan deles opp i og samtidig beholde sitt innhold og sine kjemiske egenskaper. Molekyler identifiseres med grunnstoffsymbolet og et indeks som angir antall atomer.<\/p>\n\n\n\n

Toatomige molekyler dannes n\u00e5r bare to atomer kommer sammen. Karbonmonoksid (CO) er et toatomig molekyl som best\u00e5r av ett karbonatom og ett oksygenatom. Et homonukle\u00e6rt toatomig molekyl dannes n\u00e5r to atomer av n\u00f8yaktig samme grunnstoff, for eksempel oksygen (O2) og nitrogen (N) (N2). Polyatomiske molekyler, som vann (H2O) og karbondioksid, best\u00e5r av mer enn to atomer (CO2). Polymerer er st\u00f8rre molekyler som kan inneholde tusenvis av atomer.<\/p>\n\n\n\n

Som molekyler kan atomer settes sammen p\u00e5 mange forskjellige m\u00e5ter. Flere molekyler kan dannes ved \u00e5 kombinere de samme atomene i ulike mengder. Vann (H2O) dannes av to hydrogenatomer og ett oksygenatom, mens hydrogenperoksid dannes av to hydrogenatomer og to oksygenatomer (H2O2). Og de samme atomene kan kombineres i samme forhold, men med ulik fysisk struktur. Den fysiske strukturen til et molekyl bestemmer dets egenskaper. <\/p>\n\n\n\n

Molekyldesign<\/h2>\n\n\n\n

En molekyldesign er en teknisk\/vitenskapelig konstruksjon som kombinerer to eller flere komponenter for \u00e5 generere et nytt biologisk stoff.<\/p>\n\n\n\n

Chemists employ technical expertise and do manual experimentation with the molecule design, introducing and removing functional groups \u2013 groupings of atoms and bonds with specified qualities. Even when using methods that anticipate ideal desired attributes, chemists must still perform each modification step manually. This can take a long time at each stage and yet not yield molecules with the appropriate characteristics.<\/p>\n\n\n\n

<\/div>\n\n\n
\n
\"\"\/<\/figure><\/div>\n\n\n

<\/a><\/p>\n\n\n\n

<\/div>\n\n\n\n

Hensikten bak Molecule Design<\/h2>\n\n\n\n

N\u00e5r det gjelder legemiddelindustrien, er molekyldesign en verdifull ressurs. Hver gang et nytt kreftlegemiddel lanseres, er det et resultat av innsatsen til forskere som har jobbet i \u00e5revis i kulissene for \u00e5 utvikle og teste et nytt molekyldesign.<\/p>\n\n\n\n

Form\u00e5let med \u00e5 endre molekylstrukturen er \u00e5 gj\u00f8re medisinen s\u00e5 effektiv som mulig, samtidig som den skal v\u00e6re trygg og enkel \u00e5 produsere. Denne typen arbeid inneb\u00e6rer at man m\u00e5 konstruere hver enkelt alternative molekylstruktur som skal testes, noe som er en tidkrevende operasjon selv om forskerne bare har til hensikt \u00e5 endre p\u00e5 ett enkelt karbonatom - de m\u00e5 nemlig velge blant tusenvis av ulike muligheter for \u00e5 bygge denne strukturen.<\/p>\n\n\n\n

En m\u00e5te \u00e5 gj\u00f8re dette p\u00e5 er ved hjelp av dataassistert molekyl\u00e6r design (CAMD). Legemiddelutvikling er en probleml\u00f8sende prosess som begynner med m\u00e5let om \u00e5 lokalisere riktig molekyl og riktig fysiokjemisk egenskap i et bestemt molekylrom. Det er her CAMD-algoritmen begynner \u00e5 operere, ved \u00e5 designe og utvikle aktive legemiddelkomponenter samt molekyldesignet, der hjelpestoffene og b\u00e6remolekylene velges. <\/p>\n\n\n\n

CAMD kom for \u00e5 demonstrere hvordan den kan h\u00e5ndtere farmas\u00f8ytiske problemer og hvordan tidkrevende pr\u00f8ve-og-feile-teknikker i stor grad kan erstattes av datamaskiner. <\/p>\n\n\n\n

Flere nye teknikker er under utvikling, blant annet en maskinl\u00e6ringsmodell utviklet av MIT-forskere<\/a> som kan hjelpe kjemikere med \u00e5 produsere molekyler med h\u00f8yere potens mye raskere ved \u00e5 automatisere molekyldesign for \u00e5 fremskynde utviklingen av medisiner. <\/p>\n\n\n\n

<\/div>\n\n\n
\n
\"\"\/<\/figure><\/div>\n\n\n

<\/a><\/p>\n\n\n\n

<\/div>\n\n\n\n

Jobb side om side med dyktige grafiske designere for \u00e5 skape den riktige illustrasjonen for forskningen din.<\/h2>\n\n\n\n

Visuelle elever utgj\u00f8r 65% av befolkningen, if\u00f8lge en studie<\/a>kan det v\u00e6re mer effektivt \u00e5 integrere visuelle elementer i artikler for \u00e5 kommunisere historien. Infografikk bruker visuelle hjelpemidler som diagrammer, grafer og figurer for \u00e5 gj\u00f8re det lettere \u00e5 forst\u00e5 kompliserte emner. Samarbeid med Se opp for grafen<\/a>\u2019s expert graphic designers to create the right illustration for your research and increase the exposure of your work!<\/p>\n\n\n\n

<\/div>\n\n\n
\n
\"\"<\/figure><\/div>\n\n\n
<\/div>\n\n\n\n
\n
\u00d8ke forskningen min med illustrasjoner<\/a><\/div>\n<\/div>\n\n\n\n
<\/div>\n\n\n\n
<\/div>\n\n\n\n

<\/p>","protected":false},"excerpt":{"rendered":"

Cellul\u00e6r- og molekyl\u00e6rbiologien har blitt mye bedre i det siste. Finn ut hva molekyldesign er og hvordan det revolusjonerer vitenskapen.<\/p>","protected":false},"author":28,"featured_media":26109,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[959,28],"tags":[],"yoast_head":"\nWhat is a Molecule Design and what purpose does it serve?<\/title>\n<meta name=\"description\" content=\"Cellular and molecular biology has lately improved substantially; find out what molecule design is and how it is revolutionizing science.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mindthegraph.com\/blog\/nb\/molekyl-design\/\" \/>\n<meta property=\"og:locale\" content=\"nb_NO\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"What is a Molecule Design and what purpose does it serve?\" \/>\n<meta property=\"og:description\" content=\"Cellular and molecular biology has lately improved substantially; find out what molecule design is and how it is revolutionizing science.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/mindthegraph.com\/blog\/nb\/molekyl-design\/\" \/>\n<meta property=\"og:site_name\" content=\"Mind the Graph Blog\" \/>\n<meta property=\"article:published_time\" content=\"2023-01-06T17:55:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-01-12T20:14:12+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2023\/01\/what-is-molecule-design-blog.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1123\" \/>\n\t<meta property=\"og:image:height\" content=\"612\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Jessica Abbadia\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:title\" content=\"What is a Molecule Design and what purpose does it serve?\" \/>\n<meta name=\"twitter:description\" content=\"Cellular and molecular biology has lately improved substantially; find out what molecule design is and how it is revolutionizing science.\" \/>\n<meta name=\"twitter:image\" content=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2023\/01\/what-is-molecule-design-blog.jpg\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica Abbadia\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"What is a Molecule Design and what purpose does it serve?","description":"Cellular and molecular biology has lately improved substantially; find out what molecule design is and how it is revolutionizing science.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/mindthegraph.com\/blog\/nb\/molekyl-design\/","og_locale":"nb_NO","og_type":"article","og_title":"What is a Molecule Design and what purpose does it serve?","og_description":"Cellular and molecular biology has lately improved substantially; find out what molecule design is and how it is revolutionizing science.","og_url":"https:\/\/mindthegraph.com\/blog\/nb\/molekyl-design\/","og_site_name":"Mind the Graph Blog","article_published_time":"2023-01-06T17:55:00+00:00","article_modified_time":"2023-01-12T20:14:12+00:00","og_image":[{"width":1123,"height":612,"url":"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2023\/01\/what-is-molecule-design-blog.jpg","type":"image\/jpeg"}],"author":"Jessica Abbadia","twitter_card":"summary_large_image","twitter_title":"What is a Molecule Design and what purpose does it serve?","twitter_description":"Cellular and molecular biology has lately improved substantially; find out what molecule design is and how it is revolutionizing science.","twitter_image":"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2023\/01\/what-is-molecule-design-blog.jpg","twitter_misc":{"Written by":"Jessica Abbadia","Est. reading time":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/mindthegraph.com\/blog\/molecule-design\/","url":"https:\/\/mindthegraph.com\/blog\/molecule-design\/","name":"What is a Molecule Design and what purpose does it serve?","isPartOf":{"@id":"https:\/\/mindthegraph.com\/blog\/#website"},"datePublished":"2023-01-06T17:55:00+00:00","dateModified":"2023-01-12T20:14:12+00:00","author":{"@id":"https:\/\/mindthegraph.com\/blog\/#\/schema\/person\/96ecc2d785106e951f7773dc7c96d699"},"description":"Cellular and molecular biology has lately improved substantially; find out what molecule design is and how it is revolutionizing science.","breadcrumb":{"@id":"https:\/\/mindthegraph.com\/blog\/molecule-design\/#breadcrumb"},"inLanguage":"nb-NO","potentialAction":[{"@type":"ReadAction","target":["https:\/\/mindthegraph.com\/blog\/molecule-design\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/mindthegraph.com\/blog\/molecule-design\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/mindthegraph.com\/blog\/"},{"@type":"ListItem","position":2,"name":"What is a Molecule Design and what purpose does it serve?"}]},{"@type":"WebSite","@id":"https:\/\/mindthegraph.com\/blog\/#website","url":"https:\/\/mindthegraph.com\/blog\/","name":"Mind the Graph Blog","description":"Your science can be beautiful!","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/mindthegraph.com\/blog\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"nb-NO"},{"@type":"Person","@id":"https:\/\/mindthegraph.com\/blog\/#\/schema\/person\/96ecc2d785106e951f7773dc7c96d699","name":"Jessica Abbadia","image":{"@type":"ImageObject","inLanguage":"nb-NO","@id":"https:\/\/mindthegraph.com\/blog\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/f477bd20199beb376b04b2fda9a2cec5?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/f477bd20199beb376b04b2fda9a2cec5?s=96&d=mm&r=g","caption":"Jessica Abbadia"},"description":"Jessica Abbadia is a lawyer that has been working in Digital Marketing since 2020, improving organic performance for apps and websites in various regions through ASO and SEO. Currently developing scientific and intellectual knowledge for the community's benefit. Jessica is an animal rights activist who enjoys reading and drinking strong coffee.","sameAs":["https:\/\/www.linkedin.com\/in\/jessica-abbadia-9b834a13b\/"],"url":"https:\/\/mindthegraph.com\/blog\/nb\/author\/jessica\/"}]}},"_links":{"self":[{"href":"https:\/\/mindthegraph.com\/blog\/nb\/wp-json\/wp\/v2\/posts\/26101"}],"collection":[{"href":"https:\/\/mindthegraph.com\/blog\/nb\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mindthegraph.com\/blog\/nb\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/nb\/wp-json\/wp\/v2\/users\/28"}],"replies":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/nb\/wp-json\/wp\/v2\/comments?post=26101"}],"version-history":[{"count":3,"href":"https:\/\/mindthegraph.com\/blog\/nb\/wp-json\/wp\/v2\/posts\/26101\/revisions"}],"predecessor-version":[{"id":26122,"href":"https:\/\/mindthegraph.com\/blog\/nb\/wp-json\/wp\/v2\/posts\/26101\/revisions\/26122"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/nb\/wp-json\/wp\/v2\/media\/26109"}],"wp:attachment":[{"href":"https:\/\/mindthegraph.com\/blog\/nb\/wp-json\/wp\/v2\/media?parent=26101"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/nb\/wp-json\/wp\/v2\/categories?post=26101"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/nb\/wp-json\/wp\/v2\/tags?post=26101"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}