{"id":16657,"date":"2022-09-14T13:04:15","date_gmt":"2022-09-14T16:04:15","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=16657"},"modified":"2023-03-17T14:47:26","modified_gmt":"2023-03-17T17:47:26","slug":"success-case-xtalkdb-a-database-of-signaling-pathway-crosstalk","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/nb\/suksess-sak-xtalkdb-en-database-over-signalveier-crosstalk\/","title":{"rendered":"XTALKDB: en database over kryssp\u00e5virkning av signalveier Paper Review"},"content":{"rendered":"

Denne fantastiske artikkelen viser statistikk som oppsummerer data i XTALKDB. P\u00e5 bare noen f\u00e5 minutter har forfatteren laget en infografikk som forklarer utbredelsen av artene i XTALKDB.<\/p>\n\n\n\n

Kontroller originalartikkel her<\/a>.<\/p>\n\n\n\n

Siden vi mennesker er visuelle vesener, er bilder fortsatt den beste m\u00e5ten \u00e5 forklare forskningen din p\u00e5, med s\u00e5 mange detaljer som du \u00f8nsker.<\/p>\n\n\n\n

Forskere har utviklet en database som dokumenterer kryssp\u00e5virkningen mellom spesifikke par av signalveier og arten og vevet de er observert i.<\/strong><\/h2>\n\n\n\n

En forskergruppe ledet av Sarah Sam ved Institutt for biologiske vitenskaper (2016) rapporterte at n\u00e5r reseptorer oppfatter et eksternt signal, endrer aktiviteten til mellomliggende proteiner seg. <\/p>\n\n\n\n

Dette resulterer i regulering av transkripsjonsfaktorer, som modulerer uttrykket av m\u00e5lgener. XTalkDB inneholder detaljert informasjon om de eksperimentelle betingelsene som ligger til grunn for oppdagelsen av krysstalking for hvert veipar. <\/p>\n\n\n\n

Celler vurderer og reagerer p\u00e5 omgivelsene via signalveier. En signalvei inneholder vanligvis et veldefinert sett av regulatoriske og fysiske interaksjoner mellom reseptorer, mellomliggende signalproteiner, transkripsjonsfaktorer og m\u00e5lgener. <\/p>\n\n\n\n

XTalkDB-nettstedet har et brukervennlig grensesnitt som gj\u00f8r det mulig for forskere \u00e5 s\u00f8ke etter informasjon om krysstalking ved \u00e5 s\u00f8ke p\u00e5 en eller flere veier eller molekyler av interesse.<\/p>\n\n\n\n

Det var 650 par som inngikk i studien.<\/strong><\/p>\n\n\n\n

Grafisk sammendrag drevet av Mind the Graph<\/strong><\/h2>\n\n\n
\n
\"suksess-sak-XTALKDB-en-database-over-signalveier-krosstalk\"<\/a>
Laget med Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n

Discussing possible improvements, \u201cThe manual curation process underlying XTalkDB has its limitations, especially as we seek to expand the coverage of the database. <\/p>\n\n\n\n

Vi planlegger \u00e5 utvikle et rammeverk for naturlig spr\u00e5kbehandling som vil rangere publikasjoner basert p\u00e5 sannsynligheten for at de dokumenterer krysstale. En kurator kan deretter fokusere p\u00e5 h\u00f8yt rangerte publikasjoner\", sier de.<\/p>\n\n\n\n

Avisenes innvirkning og resultater<\/strong><\/h2>\n\n\n\n

Vi kan analysere med Altmetric<\/a> data som dette papiret inneholder, er p\u00e5 \u00f8verste del av alle beregninger i alle artikler finansiert av NIH i Dimensions. <\/strong><\/p>\n\n\n

\n
\"\"<\/a>
Kilde: https:\/\/badge.dimensions.ai\/details\/id\/pub.1052462103<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n

Bruk kraften i infografikk til \u00e5 booste artikkelen din ogs\u00e5. Pr\u00f8v Mind the Graph!<\/p>\n\n\n\n

<\/div>\n\n\n\n
\n
Pr\u00f8v Mind the Graph<\/strong><\/a><\/div>\n<\/div>\n\n\n\n
<\/div>","protected":false},"excerpt":{"rendered":"

L\u00e6r av dem som allerede har oppdaget kraften i infografikk. Denne artikkelen inneholder grafiske sammendrag laget med Mind the Graph. <\/p>","protected":false},"author":29,"featured_media":20046,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[195,958,957,960,1],"tags":[96,554,963],"yoast_head":"\nXTALKDB: a database of signaling pathway crosstalk Paper Review - Mind the Graph Blog<\/title>\n<meta name=\"description\" content=\"This amazing article brings out statistics summarizing data in XTALKDB with an infographic explaining the distribution of the species in XTALKDB.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mindthegraph.com\/blog\/nb\/suksess-sak-xtalkdb-en-database-over-signalveier-crosstalk\/\" \/>\n<meta property=\"og:locale\" content=\"nb_NO\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"XTALKDB: a database of signaling pathway crosstalk Paper Review - 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