{"id":8064,"date":"2018-08-23T15:56:09","date_gmt":"2018-08-23T18:56:09","guid":{"rendered":"https:\/\/blog.mindthegraph.com\/?p=8064"},"modified":"2022-10-18T08:30:53","modified_gmt":"2022-10-18T11:30:53","slug":"alzheimers-disease","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/lv\/alzheimersa-slimiba\/","title":{"rendered":"Alcheimera slim\u012bba: Zin\u0101tniska infografika"},"content":{"rendered":"

M\u0113s vienm\u0113r priec\u0101jamies, kad redzam m\u016bsu lietot\u0101ju apbr\u012bnojamos darbus.\u00a0Es jau rakst\u012bju<\/a> par Dr. Alessandra Martini, Dr.\u00a0Stefania Forner<\/a>\u00a0un vi\u0146u kol\u0113\u0123iem. Vi\u0146i ir Kalifornijas Universit\u0101tes p\u0113cdoktorant\u016bras p\u0113tnieki un dom\u0101 par grafiku lietot\u0101jiem. Pirms da\u017eiem m\u0113ne\u0161iem es par\u0101d\u012bju infografikas<\/a>\u00a0Dr. Stef\u0101nija Fornere (Stefania Forner) sagatavoja p\u0101rskata rakstu, kas public\u0113ts \u017eurn\u0101l\u0101 Trends in Neurosciences ar nosaukumu Synaptic impairment in Alzheimer's Disease: A disregulated symphony.<\/p>\n

\u0160odien v\u0113los run\u0101t par vi\u0146u jauno p\u0101rskata rakstu ar nosaukumu No pag\u0101tnes uz n\u0101kotni: ko dz\u012bvnieku mode\u013ci mums ir iem\u0101c\u012bju\u0161i par Alcheimera slim\u012bbu.<\/a><\/p>\n

Alcheimera slim\u012bba (Alcheimera slim\u012bba) ir neirode\u0123enerat\u012bva slim\u012bba, kas izraisa kognit\u012bvo funkciju trauc\u0113jumus un atmi\u0146as zudumu. Lai uzlabotu pacientu dz\u012bves kvalit\u0101ti un atrastu efekt\u012bvu \u0101rst\u0113\u0161anu, ir svar\u012bgi izprast slim\u012bbas meh\u0101nismu. Neraugoties uz milz\u012bgaj\u0101m p\u016bl\u0113m akad\u0113miskaj\u0101s aprind\u0101s un farm\u0101cijas r\u016bpniec\u012bb\u0101, \u0161obr\u012bd nav pieejami efekt\u012bvi \u0101rst\u0113\u0161anas l\u012bdzek\u013ci. Alcheimera slim\u012bba ir sestais galvenais n\u0101ves c\u0113lonis ASV un skar 35 miljonus cilv\u0113ku vis\u0101 pasaul\u0113.<\/p>\n

Alcheimera slim\u012bbas infografika<\/h2>\n

 <\/p>\n

Liel\u0101k\u0101 da\u013ca AD pacientu ir vec\u0101ka gadag\u0101juma cilv\u0113ki, kuriem parasti ir da\u017e\u0101das blakusslim\u012bbas. Diab\u0113ts, osteoporoze, nieru slim\u012bbas, aptauko\u0161an\u0101s, hipertensija un hiperholesterolejmija\/dislipid\u0113mija, insults un krampji ir galven\u0101s blakusslim\u012bbas, kas ietekm\u0113 Alcheimera slim\u012bbas s\u0101kumu un progres\u0113\u0161anu, t\u0101d\u0113j\u0101di sare\u017e\u0123\u012b slim\u012bbas pato\u0123en\u0113zi.<\/p>\n

\"infografika
Infografika, kur\u0101 par\u0101d\u012btas Alcheimera slim\u012bbas (AD) blakusslim\u012bbas. Pag\u0101tne n\u0101kotnei: Ko dz\u012bvnieku mode\u013ci mums ir iem\u0101c\u012bju\u0161i par Alcheimera slim\u012bbu?<\/figcaption><\/figure>\n

 <\/p>\n

\n

Neraugoties uz intens\u012bviem p\u0113t\u012bjumiem p\u0113d\u0113jo desmitga\u017eu laik\u0101, joproj\u0101m nav zin\u0101mi meh\u0101nismi, kas ir spor\u0101disk\u0101s Alcheimera slim\u012bbas (sAD), kas ir visizplat\u012bt\u0101k\u0101 slim\u012bbas forma, etiolo\u0123ijas pamat\u0101. Tas vismaz da\u013c\u0113ji ir saist\u012bts ar to, ka liel\u0101k\u0101 da\u013ca sAD pacientu ir vec\u0101ka gadag\u0101juma cilv\u0113ki, kuriem parasti ir da\u017e\u0101das blakusslim\u012bbas (piem\u0113ram, insults, stress, diab\u0113ts, krampji, osteoporoze un nieru slim\u012bbas).<\/em><\/p>\n<\/blockquote>\n

N\u0101kamaj\u0101 infografik\u0101 par\u0101d\u012bta tau un beta amilo\u012bda oligom\u0113ru veido\u0161an\u0101s un sinaptisk\u0101 toksiskuma meh\u0101nismi.<\/p>\n

 <\/p>\n

\"infografika
Pag\u0101tne n\u0101kotnei: Ko mums par Alcheimera slim\u012bbu ir iem\u0101c\u012bju\u0161i dz\u012bvnieku mode\u013ci?<\/figcaption><\/figure>\n

 <\/p>\n

\n

Tauop\u0101tiju laik\u0101 samazin\u0101s dendr\u012btisko muguri\u0146u skaits. Tau nenon\u0101k neirona kodol\u0101, k\u0101 rezult\u0101t\u0101 rodas DNS boj\u0101jumi. Samazin\u0101s mitohondriju skaits, k\u0101 ar\u012b presinaptisko vezikulu skaits, kas izraisa sinaptisko zudumu. \u0160\u0101du zudumu izraisa ar\u012b tau iek\u013c\u016b\u0161ana dendr\u012btos un postsinaptiskaj\u0101s zon\u0101s. Tau agreg\u0113jas ar\u012b ekstracelul\u0101ri, \u013caujot to uz\u0146emt citiem neironiem.<\/em><\/p>\n<\/blockquote>\n

 <\/p>\n

Vi\u0146a izveidoja ar\u012b infografiku, lai par\u0101d\u012btu iekaisuma meh\u0101nismus, kas saist\u012bti ar Alcheimera slim\u012bbu (AD).<\/p>\n

 <\/p>\n

\"infografico<\/p>\n

 <\/p>\n

\n

P\u0113d\u0113jos gados m\u016bs \u012bpa\u0161i interes\u0113, k\u0101 iekaisums ietekm\u0113 beta amilo\u012bda un tau patolo\u0123iju. Gados vec\u0101ki cilv\u0113ki ir uz\u0146\u0113m\u012bgi pret v\u012brusu un bakt\u0113riju infekcij\u0101m, un \u0161ie mikrobiolo\u0123iskie a\u0123enti var\u0113tu saasin\u0101t smadze\u0146u iekaisuma st\u0101vokli, pa\u0101trinot kognit\u012bvo funkciju pasliktin\u0101\u0161anos.<\/em><\/p>\n<\/blockquote>\n

Apsveicam Dr. Stef\u0101niju Forneri par j\u016bsu lielisko darbu!<\/p>\n

Ja esat zin\u0101tnieks un v\u0113laties izveidot skaistus skait\u013cus savam darbam, varat k\u013c\u016bt par \"mind the graph\" lietot\u0101ju jau tagad.<\/p>\n

\"bez<\/a><\/p>","protected":false},"excerpt":{"rendered":"

M\u0113s vienm\u0113r priec\u0101jamies, kad redzam m\u016bsu lietot\u0101ju apbr\u012bnojamos darbus. Es jau rakst\u012bju par Dr. Alessandra Martini, Dr. Stefania Forner un vi\u0146u kol\u0113\u0123u p\u0113t\u012bjumiem. Vi\u0146i ir Kalifornijas Universit\u0101tes p\u0113cdoktorant\u016bras p\u0113tnieki un dom\u0101 par grafiku lietot\u0101jiem. Pirms da\u017eiem m\u0113ne\u0161iem es par\u0101d\u012bju infografikas, ko Dr. Stefania Forner izveidoja p\u0101rskata rakstam, kas public\u0113ts \u017eurn\u0101l\u0101 Trends [...].<\/p>","protected":false},"author":11,"featured_media":8067,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"image","meta":[],"categories":[195,958,957],"tags":[96,554],"yoast_head":"\nAlzheimer\u2019s disease: A scientific infographic - Mind the Graph Blog<\/title>\n<meta name=\"description\" content=\"Alzheimer\u2019s Disease is a neurodegenerative disorder that causes cognitive deficits and memory loss.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mindthegraph.com\/blog\/lv\/alzheimers-sykdom\/\" \/>\n<meta property=\"og:locale\" content=\"lv_LV\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Alzheimer\u2019s disease: A scientific infographic - 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