{"id":5346,"date":"2016-03-03T13:41:11","date_gmt":"2016-03-03T16:41:11","guid":{"rendered":"https:\/\/blog.mindthegraph.com\/?p=5346"},"modified":"2022-10-18T08:29:24","modified_gmt":"2022-10-18T11:29:24","slug":"zika-virus-graphical-abstract","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/lv\/zika-virus-graphical-abstract\/","title":{"rendered":"Zikas v\u012brusa grafiskais kopsavilkums par mikrocef\u0101liju"},"content":{"rendered":"

Izpratne par Zikas v\u012brusa grafisko anot\u0101ciju: k\u0101 tas samazina smadze\u0146u izm\u0113ru<\/h3>\n

\u0160odien veikts p\u0113t\u012bjums papildin\u0101ja interesantus pier\u0101d\u012bjumus par Zikas v\u012brusa lomu nervu audu malform\u0101cij\u0101. Ak, j\u0101, pirms j\u016bs jaut\u0101jat, cilv\u0113ka nervu audi.<\/p>\n

To eleganti paveica Dr. St\u012bvensa Reena (Dr. Stevens Rehen), starptautiski paz\u012bstama p\u0113tnieka cilmes \u0161\u016bnu izp\u0113tes un nesen ar\u012b \u0161\u016bnu p\u0101rprogramm\u0113\u0161anas jom\u0101, grupa.<\/p>\n

N\u0101kamaj\u0101 att\u0113l\u0101 apkopoti konstat\u0113jumi par pap\u012brs<\/a>, bet es m\u0113\u0123in\u0101\u0161u to \u012bsi izskaidrot.<\/p>\n

 <\/p>\n

\"blogs<\/p>\n

\u0160\u012b insightful Zikas v\u012brusa grafiskais kopsavilkums tika veikta ar Mind the graph. Vai tas nav for\u0161i?<\/em><\/p>\n

 <\/p>\n

 <\/p>\n

K\u0101 redzams att\u0113l\u0101, \u0161aj\u0101 p\u0113t\u012bjum\u0101 tika izmantotas tr\u012bs da\u017e\u0101das pieejas. Visas t\u0101s apstiprina, ka Zikas v\u012brusam ir tie\u0161a ietekme uz to, k\u0101 smadze\u0146u \u0161\u016bnas att\u012bst\u0101s, lai veidotu pareizus neironu audus jeb \"smadze\u0146u malform\u0101ciju\".\"zikas<\/a>Mikrocef\u0101lija ir tikai viena no smadze\u0146u malform\u0101cij\u0101m. \u0160aj\u0101 dokument\u0101 ir ierosin\u0101ts kaut kas v\u0113l b\u016btisk\u0101ks.<\/p>\n

Tie par\u0101da, k\u0101 Zikas v\u012bruss:<\/p>\n

    \n
  1. Veicina \u0161\u016bnu n\u0101vi<\/li>\n
  2. Izraisa morfolo\u0123iskas izmai\u0146as (neirosf\u0113r\u0101s).<\/li>\n
  3. Samazina smadze\u0146u organo\u012bdu (mini smadze\u0146u) aug\u0161anu\/izm\u0113ru.<\/li>\n<\/ol>\n

    Visi \u0161ie ir veidi, k\u0101 Zikas v\u012bruss ietekm\u0113 neirog\u0113zi cilv\u0113ka smadze\u0146u att\u012bst\u012bbas laik\u0101 un izraisa t\u0101l\u0101k redzamo fenotipu.<\/p>\n

    \"zikas<\/a><\/p>\n

    <\/h3>\n

    K\u0101p\u0113c tas netika dar\u012bts agr\u0101k?<\/h3>\n

    Lai var\u0113tu p\u0113t\u012bt v\u012brusu infekciju cilv\u0113ka \u0161\u016bn\u0101s, tika izmantota revolucion\u0101ra pieeja, izmantojot induc\u0113tas pluripotences cilmes \u0161\u016bnas (iPS \u0161\u016bnas).<\/p>\n

    Izmantojot \u0161o procesu, no cilv\u0113ka ieg\u016bta somatisk\u0101 \u0161\u016bna tiek p\u0101rprogramm\u0113ta uz s\u0101kotn\u0113jo pluripotent\u0101s \u0161\u016bnas st\u0101vokli, un p\u0113c tam to var diferenc\u0113t da\u017e\u0101d\u0101s \u0161\u016bn\u0101s, audos un v\u0113l nesen ar\u012b org\u0101nos. Tas ir \"cilv\u0113ka audu in\u017eenierijas\" s\u0101kums.<\/p>\n

    P\u0113t\u012bjum\u0101 autori ne tikai izmantoja iPS \u0161\u016bnas, bet ar\u012b \u0123ener\u0113ja smadze\u0146u organo\u012bdi<\/a>, ko d\u0113v\u0113 ar\u012b par \"mini smadzen\u0113m\", lai saprastu, k\u0101 Zikas v\u012brusa kl\u0101tb\u016btne ietekm\u0113 \u0161o neironu audu veido\u0161anos.<\/p>\n

    \u0160\u0101das \u0161\u016bnu kult\u016bras tiek uzskat\u012btas par tr\u012bsdimensiju (3D) strukt\u016br\u0101m, un t\u0101s sniedz vair\u0101k inform\u0101cijas par org\u0101nu arhitekt\u016bru. \u0160is ir organo\u012bda gads saska\u0146\u0101 ar Ekonomists<\/a>. Izmantojot \u0161o inovat\u012bvo pieeju, zin\u0101tnieki var\u0113ja saprast, k\u0101 zikas v\u012bruss iedarbojas uz cilv\u0113ka smadze\u0146u \u0161\u016bn\u0101m, samazinot to dz\u012bvotsp\u0113ju un aug\u0161anu neirosf\u0113ru un smadze\u0146u organo\u012bdu veid\u0101.<\/p>\n

    Port\u0101ls pap\u012brs<\/a> ir pirmsdrukas versij\u0101 inovat\u012bvaj\u0101 \u017eurn\u0101l\u0101 PeerJ. J\u016bs pat varat koment\u0113t un pal\u012bdz\u0113t autoriem to uzlabot public\u0113\u0161anas procesa laik\u0101. T\u0101l\u0101k varat apskat\u012bt kopsavilkumu un pilnu piek\u013cuvi, noklik\u0161\u0137inot uz \u0161eit<\/a>.<\/p>\n

    \"zikas<\/a><\/p>\n

    Piez\u012bme: Divus m\u0113ne\u0161us p\u0113c 2016. gada marta pirmsdrukas public\u0113\u0161anas vietn\u0113 PeerJ tika public\u0113ts gal\u012bgais darbs, un, par p\u0101rsteigumu, tas bija public\u0113ts Science <\/a>Magazine, kas ir viens no presti\u017e\u0101kajiem zin\u0101tniskajiem \u017eurn\u0101liem pasaul\u0113.<\/p>\n

    -> Lasiet pilnu Garcez et al. rakstu zin\u0101tniskaj\u0101 \u017eurn\u0101l\u0101 Science <-<\/a><\/p>\n

    \"zikas<\/a><\/p>\n

    \u013baujiet vair\u0101k cilv\u0113kiem uzzin\u0101t par to, daloties ar \u0161o zi\u0146u. Tas ir glob\u0101ls sabiedr\u012bbas vesel\u012bbas jaut\u0101jums, k\u0101 jau nor\u0101d\u012bts Pasaules Vesel\u012bbas organiz\u0101cija<\/a>\u00a0(PVO).<\/p>\n

    \n

     <\/p>\n

    Uzziniet, ko PVO iesaka par Zikas v\u012brusu<\/a>\u00a0p\u0101rn\u0113s\u0101\u0161anu un infekciju:<\/p>\n

    \n

    Transmisija<\/h3>\n

    Zikas v\u012bruss galvenok\u0101rt p\u0101rn\u0113s\u0101jas uz cilv\u0113kiem ar kodumiem no Aedes<\/i> odi, kas bie\u017ei dz\u012bvo ap \u0113k\u0101m pils\u0113t\u0101s un parasti ir akt\u012bvi dienas gai\u0161aj\u0101 laik\u0101 (visliel\u0101k\u0101 kod\u0113ju aktivit\u0101te ir agri no r\u012bta un v\u0113lu p\u0113cpusdien\u0101).<\/p>\n

    Da\u017ei pier\u0101d\u012bjumi liecina, ka Zikas v\u012brusu var p\u0101rnest ar\u012b uz cilv\u0113kiem, p\u0101rlejot asinis, nododot perinat\u0101l\u0101 ce\u013c\u0101 un seksu\u0101li. Tom\u0113r \u0161ie veidi ir \u013coti reti sastopami.<\/p>\n

    Inkub\u0101cijas periods parasti ir no 2 l\u012bdz 7 dien\u0101m.<\/p>\n

    Paz\u012bmes un simptomi<\/h3>\n

    Zikas v\u012brusa infekcijai ir rakstur\u012bgs zems drudzis (zem 38,5\u00b0C), ko bie\u017ei pavada makulopapul\u0101rs izsitums. Citi bie\u017ei sastopamie simptomi ir musku\u013cu s\u0101pes, s\u0101pes loc\u012btav\u0101s ar iesp\u0113jamu piet\u016bkumu (jo \u012bpa\u0161i plaukstu un k\u0101ju s\u012bko loc\u012btavu loc\u012btav\u0101s), galvass\u0101pes, s\u0101pes aiz ac\u012bm un konjunktiv\u012bts. T\u0101 k\u0101 simptomi bie\u017ei vien ir viegli, infekcija var palikt nepaman\u012bta vai tikt nepareizi diagnostic\u0113ta k\u0101 tropu drudzis.<\/p>\n

    Paredzams, ka Zikas v\u012brusa infekcija b\u016bs \u013coti izplat\u012bta bez simptomiem, l\u012bdz\u012bgi k\u0101 citu flaviv\u012brusu, piem\u0113ram, tropu v\u012brusa, piem\u0113ram, tropu v\u012brusa un Rietumn\u012blas v\u012brusa, gad\u012bjum\u0101. Liel\u0101k\u0101 da\u013ca cilv\u0113ku piln\u012bb\u0101 izvese\u013cojas bez smag\u0101m komplik\u0101cij\u0101m, un hospitaliz\u0101cijas gad\u012bjumu skaits ir zems. L\u012bdz \u0161im nav zi\u0146ots par n\u0101ves gad\u012bjumiem saist\u012bb\u0101 ar Zikas v\u012brusu.<\/p><\/blockquote>\n

     <\/p>\n

    Atjaunin\u0101ts 2016. gada 3. maij\u0101.<\/p>","protected":false},"excerpt":{"rendered":"

    Izpratne par Zikas v\u012brusa grafisko anot\u0101ciju: k\u0101 tas samazina smadze\u0146u izm\u0113ru \u0160odien veikts p\u0113t\u012bjums, kas papildin\u0101ts ar interesantiem pier\u0101d\u012bjumiem par Zikas v\u012brusa lomu nervu audu malform\u0101cijas proces\u0101. Ak, j\u0101, pirms j\u016bs pajaut\u0101jat, cilv\u0113ka nervu audi. To eleganti veica starptautiski paz\u012bstam\u0101 p\u0113tnieka Dr. St\u012bvensa Reena (Dr. Stevens Rehen) grupa, kas nodarbojas ar Zika v\u012brusu [...].<\/p>","protected":false},"author":4,"featured_media":7136,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[956],"tags":[96,201,200,203,202,205,554,71,250,204,199],"yoast_head":"\nZika virus graphical abstract on microcephaly - Mind the Graph Blog<\/title>\n<meta name=\"description\" content=\"This insightful Zika virus graphical abstract was done with Mind the graph. 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