{"id":16657,"date":"2022-09-14T13:04:15","date_gmt":"2022-09-14T16:04:15","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=16657"},"modified":"2023-03-17T14:47:26","modified_gmt":"2023-03-17T17:47:26","slug":"success-case-xtalkdb-a-database-of-signaling-pathway-crosstalk","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/lv\/success-case-xtalkdb-a-datubase-of-signaling-pathway-crosstalk\/","title":{"rendered":"XTALKDB: signaliz\u0101cijas ce\u013cu savstarp\u0113j\u0101s saiknes datu b\u0101ze Pap\u012bra p\u0101rskats"},"content":{"rendered":"

\u0160is p\u0101rsteidzo\u0161ais raksts sniedz statistiku, apkopojot XTALKDB datus. Autors da\u017eu min\u016b\u0161u laik\u0101 ir izveidojis infografiku, kur\u0101 izskaidrots sugu izplat\u012bba XTALKDB.<\/p>\n\n\n\n

P\u0101rbaudiet ori\u0123in\u0101lais raksts \u0161eit<\/a>.<\/p>\n\n\n\n

T\u0101 k\u0101 cilv\u0113ki ir vizu\u0101las b\u016btnes, att\u0113li joproj\u0101m ir lab\u0101kais veids, k\u0101 izskaidrot savu p\u0113t\u012bjumu ar tik daudz deta\u013c\u0101m, cik v\u0113laties.<\/p>\n\n\n\n

Zin\u0101tnieki ir izstr\u0101d\u0101ju\u0161i datub\u0101zi, kas dokument\u0113 mijiedarb\u012bbu starp konkr\u0113tiem sign\u0101lu ce\u013cu p\u0101riem un sug\u0101m un audiem, kuros tie nov\u0113roti.<\/strong><\/h2>\n\n\n\n

S\u0101ras Samas (Sarah Sam) vad\u012bt\u0101 Biolo\u0123ijas zin\u0101t\u0146u katedras p\u0113tnieku grupa (2016) zi\u0146oja, ka, receptoriem uztverot \u0101r\u0113jo sign\u0101lu, main\u0101s starpposma olbaltumvielu aktivit\u0101te. <\/p>\n\n\n\n

T\u0101 rezult\u0101t\u0101 tiek regul\u0113ti transkripcijas faktori, kas modul\u0113 m\u0113r\u0137a g\u0113nu ekspresiju. Par katru ce\u013cu p\u0101ri XTalkDB re\u0123istr\u0113 detaliz\u0113tu inform\u0101ciju, aprakstot eksperiment\u0101los apst\u0101k\u013cus, k\u0101dos tika atkl\u0101ta savstarp\u0113j\u0101 mijiedarb\u012bba. <\/p>\n\n\n\n

\u0160\u016bnas nov\u0113rt\u0113 vidi un rea\u0123\u0113 uz to, izmantojot sign\u0101lu ce\u013cus. Signaliz\u0101cijas ce\u013c\u0161 parasti ietver prec\u012bzi defin\u0113tu regulat\u012bvo un fizisko mijiedarb\u012bbu kopumu starp receptoriem, starpposma sign\u0101lprote\u012bniem, transkripcijas faktoriem un m\u0113r\u0137a g\u0113niem. <\/p>\n\n\n\n

XTalkDB t\u012bmek\u013ca vietne nodro\u0161ina viegli lietojamu saskarni, kas zin\u0101tniekiem \u013cauj p\u0101rl\u016bkot inform\u0101ciju par krusteniskaj\u0101m sait\u0113m, izmantojot vienu vai vair\u0101kus interes\u0113jo\u0161os ce\u013cus vai molekulas.<\/p>\n\n\n\n

P\u0113t\u012bjum\u0101 tika iek\u013cauti 650 p\u0101ri.<\/strong><\/p>\n\n\n\n

Grafiskais abstrakts, ko nodro\u0161ina Mind the Graph<\/strong><\/h2>\n\n\n
\n
\"success-case-XTALKDB-a-datubase-of-signaling-pathway-crosstalk\"<\/a>
Izgatavots ar Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n

Apsprie\u017eot iesp\u0113jamos uzlabojumus, \"XTalkDB pamat\u0101 eso\u0161ajam manu\u0101lajam kuratora procesam ir savi ierobe\u017eojumi, jo \u012bpa\u0161i t\u0101p\u0113c, ka m\u0113s cen\u0161amies papla\u0161in\u0101t datub\u0101zes p\u0101rkl\u0101jumu. <\/p>\n\n\n\n

M\u0113s pl\u0101nojam izstr\u0101d\u0101t dabisk\u0101s valodas apstr\u0101des sist\u0113mu, kas \u013caus nov\u0113rt\u0113t publik\u0101cijas, pamatojoties uz to iesp\u0113jam\u012bbu, ka taj\u0101s ir dokument\u0113ti savstarp\u0113ji saist\u012bti jaut\u0101jumi. Tad kurators var koncentr\u0113ties uz augsti nov\u0113rt\u0113taj\u0101m publik\u0101cij\u0101m,\" vi\u0146i atz\u012bst.<\/p>\n\n\n\n

Dokumenti Ietekme un veiktsp\u0113ja<\/strong><\/h2>\n\n\n\n

M\u0113s varam analiz\u0113t ar Altmetric<\/a> dati, ka \u0161is dokuments ir par visu metriku aug\u0161\u0113j\u0101 da\u013ca visos NIH finans\u0113tajos rakstos dimensij\u0101s. <\/strong><\/p>\n\n\n

\n
\"\"<\/a>
Avots: https:\/\/badge.dimensions.ai\/details\/id\/pub.1052462103<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n

Izmantojiet infografikas iesp\u0113jas, lai uzlabotu ar\u012b savu rakstu. Izm\u0113\u0123iniet Mind the Graph!<\/p>\n\n\n\n

<\/div>\n\n\n\n
\n
Izm\u0113\u0123iniet Mind the Graph<\/strong><\/a><\/div>\n<\/div>\n\n\n\n
<\/div>","protected":false},"excerpt":{"rendered":"

M\u0101cies kop\u0101 ar tiem, kas jau atkl\u0101ju\u0161i infografikas sp\u0113ku. \u0160aj\u0101 rakst\u0101 ir grafiski kopsavilkumi, kas izveidoti ar Mind the Graph. <\/p>","protected":false},"author":29,"featured_media":20046,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[195,958,957,960,1],"tags":[96,554,963],"yoast_head":"\nXTALKDB: a database of signaling pathway crosstalk Paper Review - Mind the Graph Blog<\/title>\n<meta name=\"description\" content=\"This amazing article brings out statistics summarizing data in XTALKDB with an infographic explaining the distribution of the species in XTALKDB.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mindthegraph.com\/blog\/lv\/success-case-xtalkdb-a-datubase-of-signaling-pathway-crosstalk\/\" \/>\n<meta property=\"og:locale\" content=\"lv_LV\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"XTALKDB: a database of signaling pathway crosstalk Paper Review - 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