{"id":16630,"date":"2022-09-08T18:14:00","date_gmt":"2022-09-08T21:14:00","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/success-case-zika-virus-replicates-in-adult-human-brain-tissue-and-impairs-synapses-and-memory-in-mice-copy\/"},"modified":"2023-03-17T14:47:54","modified_gmt":"2023-03-17T17:47:54","slug":"success-case-igh-resolution-synchrotron-based-x-ray-microtomography-as-a-tool-to-unveil-the-three-dimensional-neuronal-architecture-of-the-brain","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/lv\/uz-sinhrotronu-balstita-augstas-izskirtspejas-rentgenstaru-mikrotomografija-ka-instruments-smadzenu-trisdimensiju-neironu-arhitekturas-atklasanai\/","title":{"rendered":"Augstas iz\u0161\u0137irtsp\u0113jas sinhrotron\u0101 b\u0101z\u0113ta rentgenstaru mikrotomogr\u0101fija k\u0101 instruments, lai atkl\u0101tu smadze\u0146u tr\u012bsdimensiju neironu arhitekt\u016bru Paper Review"},"content":{"rendered":"

Rentgenstaru mikrotomogr\u0101fija ir k\u013cuvusi par jaunu metodi smadze\u0146u citoarhitekt\u016bras un savienojam\u012bbas at\u0161ifr\u0113\u0161anai, un \u0161eit m\u0113s iepaz\u012bstin\u0101m ar metodi veselu neironu att\u0113lo\u0161anai.<\/p>\n\n\n\n

Augstas iz\u0161\u0137irtsp\u0113jas sinhrotron\u0101 b\u0101z\u0113ta rentgenstaru mikrotomogr\u0101fija k\u0101 r\u012bks smadze\u0146u tr\u012bsdimensiju neironu arhitekt\u016bras atkl\u0101\u0161anai<\/strong><\/h2>\n\n\n\n

Matheus de Castro Fonseca et al. (2018) rakst\u0101 \"High-resolution synchrotron-based X-ray microtomography as a tool to seveil the three-dimensional neironal architecture of the brain\" (\"Augstas iz\u0161\u0137irtsp\u0113jas sinhrotron\u0101 b\u0101z\u0113ta rentgenstaru mikrotomogr\u0101fija k\u0101 instruments, lai atkl\u0101tu smadze\u0146u tr\u012bsdimensiju neironu arhitekt\u016bru\") nor\u0101da, ka neironu k\u0101 individualiz\u0113tu vien\u012bbu izp\u0113te aizs\u0101k\u0101s 19. gadsimt\u0101, kad tika izveidota neironu doktr\u012bna. <\/p>\n\n\n\n

P\u0113d\u0113jos gados ir ieguld\u012bts liels darbs, lai izprastu neironu organiz\u0101ciju un savienojam\u012bbu neskartu smadze\u0146u paraugos. Golgi-Koksa mar\u0137\u0113\u0161anas metode pied\u0101v\u0101 piem\u0113rotu kontrastu specifiskai neironu mar\u0137\u0113\u0161anai rentgena mikrotomogr\u0101fijai. <\/p>\n\n\n\n

Neironiem ir at\u0161\u0137ir\u012bga morfolo\u0123ija un specifiski savienojam\u012bbas mode\u013ci, kas ir b\u016btiski to pareizai funkcion\u0113\u0161anai. P\u0113tnieki iepaz\u012bstina ar att\u0113lveido\u0161anas metodi, kur\u0101 apvienota sinhrotron\u0101 b\u0101z\u0113ta rentgena staru mikrotomogr\u0101fija ar Golgi-Koksa impregn\u0113\u0161anas protokolu. <\/p>\n\n\n\n

\u0160\u012b metode nodro\u0161ina augst\u0101ku un viendab\u012bg\u0101ku kontrastu sal\u012bdzino\u0161i reti izklied\u0113tiem veseliem neironiem audos.<\/p>\n\n\n\n

Smadzenes 14 dienas tika inkub\u0113tas Golgi-Cox kr\u0101so\u0161anas \u0161\u0137\u012bdum\u0101, pasarg\u0101tas no gaismas. P\u0113c inkub\u0101cijas perioda smadzenes tika sagrieztas s\u0113rijveid\u0101, izmantojot vibratomu.<\/strong><\/p>\n\n\n\n

P\u0101rbaudiet ori\u0123in\u0101lais raksts \u0161eit<\/a>.<\/p>\n\n\n\n

Grafiskais abstrakts, ko nodro\u0161ina Mind the Graph<\/strong><\/h2>\n\n\n\n
<\/div>\n\n\n
\n
\"\"<\/a>
Izgatavots ar Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n

Autors izmantoja Mind the Graph<\/a> lai izveidotu shematisku att\u0113lu, kas att\u0113lo pieaugu\u0161u peli, kurai i.p. injic\u0113 fiziolo\u0123isko \u0161\u0137\u012bdumu vai pilokarp\u012bna \u0161\u0137\u012bdumu (280 mg\/kg). Sare\u017e\u0123\u012btu procesu att\u0113lo\u0161ana ar infografikas pal\u012bdz\u012bbu ir labs veids, k\u0101 tos padar\u012bt viegli saprotamus, neatst\u0101jot mal\u0101 deta\u013cas un b\u016btisko inform\u0101ciju.<\/p>\n\n\n\n

Da\u017ei no p\u0113tnieku rezult\u0101tiem, \u0161\u0137iet, nostiprina to, kas par \u0161o jomu bija zin\u0101ms jau agr\u0101k: \"\u0160eit par\u0101d\u012bt\u0101 neironu impregn\u0113\u0161ana uz dz\u012bvsudraba b\u0101zes \u013c\u0101va mums skaidri defin\u0113t veselus neironus galvenok\u0101rt t\u0101p\u0113c, ka \u0161\u016bnu impregn\u0113\u0161ana bija nep\u0101rtraukt\u0101ka un viendab\u012bg\u0101ka un artefaktu bl\u012bvums bija daudz maz\u0101ks,\" nor\u0101da de Kastro Fonseca.<\/p>\n\n\n\n

Dokumenti Ietekme un veiktsp\u0113ja<\/strong><\/h2>\n\n\n\n

M\u0113s varam analiz\u0113t ar Altmetric<\/a> dati, ka \u0161\u012b dokumenta tie\u0161saistes uzman\u012bbas r\u0101d\u012bt\u0101js ir augst\u0101ks. nek\u0101 64%<\/strong><\/strong> no visiem citiem l\u012bdz\u012bga vecuma rakstiem izdevum\u0101 Scientific Reports.<\/strong><\/p>\n\n\n\n

<\/div>\n\n\n
\n
\"\"<\/a>
Avots: Altmetrika<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n

Uzlabojiet raksta pieejam\u012bbu, izmantojot ar\u012b infografikas iesp\u0113jas.<\/p>\n\n\n\n

\n
Izm\u0113\u0123iniet Mind the Graph<\/strong><\/a><\/div>\n<\/div>\n\n\n\n
<\/div>","protected":false},"excerpt":{"rendered":"

Iepaz\u012bstieties ar jauno metodi smadze\u0146u citoarhitekt\u016bras un savienojam\u012bbas at\u0161ifr\u0113\u0161anai, kas att\u0113lota ar Mind the Graph ilustr\u0101cij\u0101m.<\/p>","protected":false},"author":29,"featured_media":20013,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[195,958,957,960,1],"tags":[96,554,775,963],"yoast_head":"\nHigh-resolution synchrotron-based X-ray microtomography as a tool to unveil the three-dimensional neuronal architecture of the brain Paper Review - Mind the Graph Blog<\/title>\n<meta name=\"description\" content=\"Look into the new method for deciphering the cytoarchitecture and connectivity of the brain represented with Mind the Graph's illustrations.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mindthegraph.com\/blog\/lv\/uz-sinhrotronu-balstita-augstas-izskirtspejas-rentgenstaru-mikrotomografija-ka-instruments-smadzenu-trisdimensiju-neironu-arhitekturas-atklasanai\/\" \/>\n<meta property=\"og:locale\" content=\"lv_LV\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"High-resolution synchrotron-based X-ray microtomography as a tool to unveil the three-dimensional neuronal architecture of the brain Paper Review - Mind the Graph Blog\" \/>\n<meta property=\"og:description\" content=\"Look into the new method for deciphering the cytoarchitecture and connectivity of the brain represented with Mind the Graph's illustrations.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/mindthegraph.com\/blog\/lv\/uz-sinhrotronu-balstita-augstas-izskirtspejas-rentgenstaru-mikrotomografija-ka-instruments-smadzenu-trisdimensiju-neironu-arhitekturas-atklasanai\/\" \/>\n<meta property=\"og:site_name\" content=\"Mind the Graph Blog\" \/>\n<meta property=\"article:published_time\" content=\"2022-09-08T21:14:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-03-17T17:47:54+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/blog_2.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1125\" \/>\n\t<meta property=\"og:image:height\" content=\"614\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Artur Zignani\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:image\" content=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/blog_2.jpg\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Artur Zignani\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"High-resolution synchrotron-based X-ray microtomography as a tool to unveil the three-dimensional neuronal architecture of the brain Paper Review - Mind the Graph Blog","description":"Look into the new method for deciphering the cytoarchitecture and connectivity of the brain represented with Mind the Graph's illustrations.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/mindthegraph.com\/blog\/lv\/uz-sinhrotronu-balstita-augstas-izskirtspejas-rentgenstaru-mikrotomografija-ka-instruments-smadzenu-trisdimensiju-neironu-arhitekturas-atklasanai\/","og_locale":"lv_LV","og_type":"article","og_title":"High-resolution synchrotron-based X-ray microtomography as a tool to unveil the three-dimensional neuronal architecture of the brain Paper Review - Mind the Graph Blog","og_description":"Look into the new method for deciphering the cytoarchitecture and connectivity of the brain represented with Mind the Graph's illustrations.","og_url":"https:\/\/mindthegraph.com\/blog\/lv\/uz-sinhrotronu-balstita-augstas-izskirtspejas-rentgenstaru-mikrotomografija-ka-instruments-smadzenu-trisdimensiju-neironu-arhitekturas-atklasanai\/","og_site_name":"Mind the Graph Blog","article_published_time":"2022-09-08T21:14:00+00:00","article_modified_time":"2023-03-17T17:47:54+00:00","og_image":[{"width":1125,"height":614,"url":"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/blog_2.jpg","type":"image\/jpeg"}],"author":"Artur Zignani","twitter_card":"summary_large_image","twitter_image":"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/blog_2.jpg","twitter_misc":{"Written by":"Artur Zignani","Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/mindthegraph.com\/blog\/success-case-igh-resolution-synchrotron-based-x-ray-microtomography-as-a-tool-to-unveil-the-three-dimensional-neuronal-architecture-of-the-brain\/","url":"https:\/\/mindthegraph.com\/blog\/success-case-igh-resolution-synchrotron-based-x-ray-microtomography-as-a-tool-to-unveil-the-three-dimensional-neuronal-architecture-of-the-brain\/","name":"High-resolution synchrotron-based X-ray microtomography as a tool to unveil the three-dimensional neuronal architecture of the brain Paper Review - Mind the Graph Blog","isPartOf":{"@id":"https:\/\/mindthegraph.com\/blog\/#website"},"datePublished":"2022-09-08T21:14:00+00:00","dateModified":"2023-03-17T17:47:54+00:00","author":{"@id":"https:\/\/mindthegraph.com\/blog\/#\/schema\/person\/b44995c1d77b52a63b6d11262b740b02"},"description":"Look into the new method for deciphering the cytoarchitecture and connectivity of the brain represented with Mind the Graph's illustrations.","breadcrumb":{"@id":"https:\/\/mindthegraph.com\/blog\/success-case-igh-resolution-synchrotron-based-x-ray-microtomography-as-a-tool-to-unveil-the-three-dimensional-neuronal-architecture-of-the-brain\/#breadcrumb"},"inLanguage":"lv","potentialAction":[{"@type":"ReadAction","target":["https:\/\/mindthegraph.com\/blog\/success-case-igh-resolution-synchrotron-based-x-ray-microtomography-as-a-tool-to-unveil-the-three-dimensional-neuronal-architecture-of-the-brain\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/mindthegraph.com\/blog\/success-case-igh-resolution-synchrotron-based-x-ray-microtomography-as-a-tool-to-unveil-the-three-dimensional-neuronal-architecture-of-the-brain\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/mindthegraph.com\/blog\/"},{"@type":"ListItem","position":2,"name":"High-resolution synchrotron-based X-ray microtomography as a tool to unveil the three-dimensional neuronal architecture of the brain Paper Review"}]},{"@type":"WebSite","@id":"https:\/\/mindthegraph.com\/blog\/#website","url":"https:\/\/mindthegraph.com\/blog\/","name":"Mind the Graph Blog","description":"Your science can be beautiful!","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/mindthegraph.com\/blog\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"lv"},{"@type":"Person","@id":"https:\/\/mindthegraph.com\/blog\/#\/schema\/person\/b44995c1d77b52a63b6d11262b740b02","name":"Artur Zignani","image":{"@type":"ImageObject","inLanguage":"lv","@id":"https:\/\/mindthegraph.com\/blog\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/a211ec97011fe24f7a8e63a7ca799342?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/a211ec97011fe24f7a8e63a7ca799342?s=96&d=mm&r=g","caption":"Artur Zignani"},"url":"https:\/\/mindthegraph.com\/blog\/lv\/author\/artur\/"}]}},"_links":{"self":[{"href":"https:\/\/mindthegraph.com\/blog\/lv\/wp-json\/wp\/v2\/posts\/16630"}],"collection":[{"href":"https:\/\/mindthegraph.com\/blog\/lv\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mindthegraph.com\/blog\/lv\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/lv\/wp-json\/wp\/v2\/users\/29"}],"replies":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/lv\/wp-json\/wp\/v2\/comments?post=16630"}],"version-history":[{"count":5,"href":"https:\/\/mindthegraph.com\/blog\/lv\/wp-json\/wp\/v2\/posts\/16630\/revisions"}],"predecessor-version":[{"id":27198,"href":"https:\/\/mindthegraph.com\/blog\/lv\/wp-json\/wp\/v2\/posts\/16630\/revisions\/27198"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/lv\/wp-json\/wp\/v2\/media\/20013"}],"wp:attachment":[{"href":"https:\/\/mindthegraph.com\/blog\/lv\/wp-json\/wp\/v2\/media?parent=16630"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/lv\/wp-json\/wp\/v2\/categories?post=16630"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/lv\/wp-json\/wp\/v2\/tags?post=16630"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}