{"id":16092,"date":"2022-07-22T14:22:56","date_gmt":"2022-07-22T17:22:56","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=16092"},"modified":"2022-10-18T08:29:39","modified_gmt":"2022-10-18T11:29:39","slug":"covid-or-the-effect-of-vaccination","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/lv\/covid-or-the-effect-of-vaccination\/","title":{"rendered":"Vai t\u0101 ir COVID vai vakcin\u0101cijas ietekme? Kardiovaskul\u0101r\u0101s \u0101rk\u0101rtas situ\u0101cijas"},"content":{"rendered":"

P\u0113c COVID 19 visgr\u016bt\u0101ko laiku p\u0101rvar\u0113\u0161anas cilv\u0113ce ir atradusi cer\u012bbu vakcin\u0101cij\u0101. Visi jaunie biotehnolo\u0123ijas sasniegumi \u013c\u0101va mums c\u012bn\u012bties ar COVID smagajiem laikiem. God\u012bgi sakot, laika bija maz\u0101k, un cilv\u0113ki mira. Cilv\u0113ce c\u012bn\u012bj\u0101s ne tikai, lai atrastu c\u0113loni, bet ar\u012b lai izdz\u012bvotu! <\/p>\n\n\n\n

Par pand\u0113mijas apkaro\u0161anas l\u012bdzek\u013ciem k\u013cuva daudznozaru pieeja, \u0101tr\u0101ka likumdo\u0161anas darb\u012bba un sabiedr\u012bbas atbalsts. Nepiecie\u0161am\u012bba tikt gal\u0101 ar laika tr\u016bkumu, ko mums rad\u012bja COVID, noveda pie vakc\u012bnas ra\u017eo\u0161anas faktu izseko\u0161anas, bet t\u0101 ar\u012b cent\u0101s pan\u0101kt \u0101tr\u0101ku apstiprin\u0101\u0161anu, neizp\u0113tot jaunrad\u012bto molekulu ilgtermi\u0146a ietekmi.<\/p>\n\n\n\n

Visi sp\u0113ki cent\u0101s ierobe\u017eot nezin\u0101m\u0101 apdraud\u0113juma izplat\u012b\u0161anos, un medic\u012bnas dienestu sl\u0101\u0146i sabruka! Tajos br\u012b\u017eos tika ierosin\u0101tas un p\u0101rbaud\u012btas vakc\u012bnas molekulas. Pati slim\u012bba nebija l\u012bdz galam zin\u0101ma, un ilgtermi\u0146a sekas izklaus\u012bj\u0101s p\u0113c meln\u0101 cauruma. Visas valstis un vald\u012bbas piekrita nodro\u0161in\u0101t bezmaksas vakcin\u0101ciju, lai gl\u0101btu cilv\u0113kus, tom\u0113r no zin\u0101tnisk\u0101 viedok\u013ca bija daudz spekul\u0101ciju par to, k\u0101da b\u016bs visu COVID vakcin\u0101cijas pas\u0101kumu \u012bstermi\u0146a un ilgtermi\u0146a ietekme uz cilv\u0113kiem.<\/p>\n\n\n\n

P\u0113c trim gadiem kop\u0161 pirm\u0101 slim\u012bbas uzliesmojuma p\u0113tnieki ir s\u0101ku\u0161i detaliz\u0113ti analiz\u0113t datus, lai atrastu sakar\u012bbas un tendences, izmantojot da\u017e\u0101dus sal\u012bdzin\u0101jumus. Izmantojot \u0161o jauno Mind the Graph rakstu veidu, m\u0113s cen\u0161amies sniegt ieskatu par visvair\u0101k las\u012btajiem rakstiem zin\u0101mos \u017eurn\u0101los noteikt\u0101 laika posm\u0101. M\u016bsu eksperti izskata rakstus, sagatavo grafiskus att\u0113lojumus un pasniedz tos, lai lab\u0101k izprastu m\u016bsu viedokli. M\u0113s nev\u0113lamies, lai j\u016bs nepalaistu gar\u0101m nevienu labu rakstu un tehnolo\u0123iju jaunumus, kurus m\u0113s varam izgaismot.<\/p>\n\n\n\n

\u0160oned\u0113\u013c public\u0113t\u0101 p\u0113t\u012bjuma raksta nosaukums ir, \"Paaugstin\u0101ts neatliekamo kardiovaskul\u0101ro notikumu skaits jaun\u0101ku par 40 gadiem iedz\u012bvot\u0101ju vid\u016b Izra\u0113l\u0101 vakc\u012bnas ievie\u0161anas un tre\u0161\u0101 COVID-19 vi\u013c\u0146a laik\u0101\"<\/a> un taj\u0101 galvenok\u0101rt tiek run\u0101ts par \u0101rk\u0101rtas situ\u0101cij\u0101m sirdsdarb\u012bb\u0101, kas nov\u0113rotas p\u0113c COVID vakcin\u0101cijas, un retrospekt\u012bvi sal\u012bdzin\u0101tas ar \u0101rk\u0101rtas situ\u0101cij\u0101m sirdsdarb\u012bb\u0101 p\u0113c COVID vakcin\u0101cijas.<\/p>\n\n\n\n

Pirms s\u0101kam iedzi\u013cin\u0101ties raksta metodolo\u0123ij\u0101 un nov\u0113rojumos, s\u0101ksim ar pamatizpratnes g\u016b\u0161anu par vakc\u012bnu zin\u0101tnes procesu vakc\u012bnu izstr\u0101d\u0113.<\/p>\n\n\n\n

Vakc\u012bnas - kas t\u0101s ir?<\/strong><\/strong><\/h2>\n\n\n\n

P\u0113c v\u0101rdn\u012bcas defin\u012bcijas vakc\u012bnas ir nelielas im\u016bndzeno\u0161as da\u013ci\u0146as, nov\u0101jin\u0101tu, nogalin\u0101tu vai fragment\u0113tu mikroorganismu vai toks\u012bnu suspensija vai cits biolo\u0123isks prepar\u0101ts, piem\u0113ram, sast\u0101v no antiviel\u0101m, limfoc\u012btiem vai zi\u0146ne\u0161a RNS (mRNS), ko galvenok\u0101rt lieto, lai nov\u0113rstu slim\u012bbu. Kad cilv\u0113ka organisms tiek pak\u013cauts nov\u0101jin\u0101tu antig\u0113na da\u013ci\u0146u iedarb\u012bbai, t\u0101s m\u0113dz izrais\u012bt saimnieka organisma imunolo\u0123isko reakciju, bet ne vienm\u0113r slim\u012bbu.<\/p>\n\n\n\n

Vakc\u012bnas molekulas atg\u0101dina patog\u0113nus un izraisa im\u016bnreakciju, lai aktiviz\u0113tu IGg ra\u017eojo\u0161\u0101s B \u0161\u016bnas un izrais\u012btu atmi\u0146as veido\u0161anos antivielu veido\u0161anai pret attiec\u012bgo molekulu. \u0160is meh\u0101nisms pal\u012bdz cilv\u0113kiem ieg\u016bt ilgtermi\u0146a un \u012bstermi\u0146a aizsardz\u012bbu pret infekciju. COVID vakc\u012bnas izstr\u0101d\u0101 ar\u012b farm\u0101cijas uz\u0146\u0113mumi, lai pasarg\u0101tu m\u016bs no let\u0101las slim\u012bbas prognozes un n\u0101ves.<\/p>\n\n\n\n

COVID komplik\u0101cijas<\/strong><\/strong><\/h2>\n\n\n\n

SARS COVID 19 v\u012bruss ir apdraud\u0113jis cilv\u0113ka eksistenci. \u0160\u012b m\u0113ne\u0161a tematiskaj\u0101 rakst\u0101 st\u0101st\u012bts par da\u017e\u0101d\u0101m sirds komplik\u0101cij\u0101m, ko slim\u012bba izraisa t\u0101s infekcijas cikla laik\u0101, un t\u0101s ilgtermi\u0146a sek\u0101m. Autori Christopher L.F., Eli Jaffe & Retsef Levi no Izra\u0113las ir sniegu\u0161i \u012bsu p\u0101rskatu par COVID izrais\u012btaj\u0101m sirds un asinsvadu komplik\u0101cij\u0101m.<\/p>\n\n\n\n

Tajos min\u0113ts, ka asins rec\u0113\u0161ana, ak\u016bts koron\u0101rs sindroms, sirdsdarb\u012bbas apst\u0101\u0161an\u0101s un miokard\u012bts ir bie\u017eas COVID blakuspar\u0101d\u012bbas. Ir zi\u0146ots par vair\u0101ku org\u0101nu boj\u0101jumu gad\u012bjumiem COVID lieto\u0161anas laik\u0101 un p\u0113c COVID lieto\u0161anas. Gados vec\u0101kiem cilv\u0113kiem k\u013c\u016bst gr\u016bti nodal\u012bt slim\u012bbas ietekmi un vecuma un iepriek\u0161 past\u0101vo\u0161o kl\u012bnisko st\u0101vok\u013cu ietekmi. T\u0101d\u0113j\u0101di autoru iesniegtais p\u0113t\u012bjums noteikti piesaista m\u016bsu uzman\u012bbu domin\u0113jo\u0161o neatliekam\u0101s medic\u012bnisk\u0101s pal\u012bdz\u012bbas apst\u0101k\u013cu d\u0113\u013c. <\/p>\n\n\n\n

Autori nov\u0113roja, ka ir j\u0101b\u016bt zin\u0101mai sakar\u012bbai starp valsts neatliekam\u0101s pal\u012bdz\u012bbas dienest\u0101 sa\u0146emto neatliekamo gad\u012bjumu skaita pieaugumu un vakcin\u0101cijas grafiku. Tom\u0113r, lai izprastu smalk\u0101s robe\u017eas starp ietekmi p\u0113c COVID vai vakcin\u0101cijas ietekmi, vai ar vecumu saist\u012btiem rezult\u0101tiem un neatliekamaj\u0101m situ\u0101cij\u0101m, bija nepiecie\u0161ama r\u016bp\u012bga un sare\u017e\u0123\u012bta p\u0113t\u012bjuma izstr\u0101de.<\/p>\n\n\n\n

Izaicin\u0101jumi, ar kuriem saskaras p\u0113tnieki - p\u0113t\u012bjuma izstr\u0101de <\/strong><\/strong><\/h2>\n\n\n\n

P\u0113t\u012bjuma raksta pamat\u0101 ir retrospekt\u012bvs iedz\u012bvot\u0101ju aptaujas p\u0113t\u012bjums par neatliekam\u0101s pal\u012bdz\u012bbas dienestiem Izra\u0113l\u0101. \u0160\u012b p\u0113t\u012bjuma m\u0113r\u0137is ir izp\u0113t\u012bt, k\u0101 papildu datu avoti, piem\u0113ram, dati no neatliekam\u0101s medic\u012bnisk\u0101s pal\u012bdz\u012bbas dienestiem (NMPD), var papildin\u0101t pa\u0161nov\u0113ro\u0161anas vakc\u012bnu uzraudz\u012bbas sist\u0113mas, lai noteiktu ar COVID-19 saist\u012btas sabiedr\u012bbas vesel\u012bbas tendences. <\/p>\n\n\n\n

\"Izmantojot unik\u0101lu datu kopu no Izra\u0113las valsts neatliekam\u0101s medic\u012bnisk\u0101s pal\u012bdz\u012bbas dienestiem (EMS) no 2019. l\u012bdz 2021. gadam, p\u0113t\u012bjuma m\u0113r\u0137is ir nov\u0113rt\u0113t saist\u012bbu starp sirdsdarb\u012bbas apst\u0101\u0161an\u0101s un ak\u016bta koron\u0101r\u0101 sindroma EMS izsaukumu apjomu 16-39 gadus vecu iedz\u012bvot\u0101ju vid\u016b ar potenci\u0101lajiem faktoriem, tostarp COVID-19 infekciju un vakcin\u0101cijas l\u012bmeni.\" <\/p>\n\n\n\n

P\u0113tnieki izmantoja negat\u012bv\u0101s binomi\u0101l\u0101s regresijas mode\u013cus, lai analiz\u0113tu ikned\u0113\u013cas neatliekam\u0101s pal\u012bdz\u012bbas izsaukumu skaitu un m\u0113\u0123in\u0101ja tos saist\u012bt ar COVID vakc\u012bnas 1. un 2. devu. Visi datu avoti bija valsts datu v\u0101k\u0161anas centri.<\/p>\n\n\n\n

<\/p>\n\n\n\n

\"\"<\/a>
No:\u00a0Paaugstin\u0101ts neatliekamo kardiovaskul\u0101ro notikumu skaits jaun\u0101ku par 40 gadiem iedz\u012bvot\u0101ju vid\u016b Izra\u0113l\u0101 vakc\u012bnas ievie\u0161anas un COVID-19 tre\u0161\u0101 vi\u013c\u0146a laik\u0101<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n\n

Nov\u0113rojumi <\/strong><\/strong><\/h2>\n\n\n\n

Tika konstat\u0113ts, ka tie bija b\u016btiski saist\u012bti ar 1. un 2. vakc\u012bnas devas ievad\u012b\u0161anas bie\u017eumu \u0161aj\u0101 vecuma grup\u0101, bet ne ar COVID-19 infekcijas bie\u017eumu. Autori ne tikai nor\u0101da uz p\u0113t\u012bjuma nov\u0113rojumiem, bet ar\u012b ierosina da\u017eas politiskas sekas. Vi\u0146i ierosina vald\u012bbas iejauk\u0161anos un pacientu un \u0101rstu inform\u0113t\u012bbas palielin\u0101\u0161anu. <\/p>\n\n\n\n

Lai gan p\u0113t\u012bjum\u0101 ir nor\u0101d\u012bti visi kritiskie r\u0101d\u012bt\u0101ji, taj\u0101 ir aprakst\u012bts ar\u012b p\u0113t\u012bjuma ierobe\u017eojums, ka tas balst\u0101s uz apkopotiem datiem, kuros nav iek\u013cauta specifiska inform\u0101cija par skartajiem pacientiem, tostarp slimn\u012bcas izn\u0101kums, pamatslim\u012bbas, k\u0101 ar\u012b vakcin\u0101cijas un COVID-19 pozit\u012bvais statuss.<\/p>\n\n\n\n

Mind the Graph <\/strong>izsaka atzin\u012bbu autoriem par vi\u0146u br\u012bni\u0161\u0137\u012bgo darbu un ieguld\u012bjumu zin\u0101tniskaj\u0101 sabiedr\u012bb\u0101. L\u016bdzu, dalieties ar saviem br\u012bni\u0161\u0137\u012bgajiem darbiem, un m\u0113s l\u016bgsim m\u016bsu komandu izcelt j\u016bsu apbr\u012bnojamo darbu ar grafisku anot\u0101ciju! Veidosim zin\u0101tni. <\/p>\n\n\n\n

<\/p>\n\n\n\n

<\/div>\n\n\n\n

<\/p>","protected":false},"excerpt":{"rendered":"

\u0160aj\u0101 rakst\u0101 ir st\u0101st\u012bts par da\u017e\u0101d\u0101m sirds komplik\u0101cij\u0101m, ko COVID-19 izraisa infekcijas cikla laik\u0101, un par t\u0101s ilgtermi\u0146a sek\u0101m. <\/p>","protected":false},"author":4,"featured_media":16097,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[419,956],"tags":[870,96,554,964],"yoast_head":"\nIs it COVID or the effect of vaccination? 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He has a Ph.D. and solid scientific background in Psychopharmacology and experience as a Guest Researcher at the Max Planck Institute of Psychiatry (Germany) and Researcher in D'Or Institute for Research and Education (IDOR, Brazil). Fabricio holds over 2500 citations in Google Scholar. He has 10 years of experience in small innovative businesses, with relevant experience in product design and innovation management. 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