{"id":15202,"date":"2021-10-29T13:59:11","date_gmt":"2021-10-29T15:59:11","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=15202"},"modified":"2023-01-05T13:07:06","modified_gmt":"2023-01-05T16:07:06","slug":"mind-the-graph-and-3d-protein-imaging-2","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/lv\/prata-grafikas-un-3d-proteinu-attelveidosanas-2\/","title":{"rendered":"Mind the Graph un 3D prote\u012bnu att\u0113lveido\u0161ana"},"content":{"rendered":"

Vai esat m\u0113\u0123in\u0101jis izveidot molekul\u0101ro ilustr\u0101ciju ar klasiskajiem molekul\u0101rajiem skat\u012bt\u0101jiem? Ja atbilde ir \"j\u0101\", tad j\u016bs jau zin\u0101t, cik gr\u016bti tas ir. <\/p>\n\n\n\n

Jums ir j\u0101atrod bezmaksas versija, kas nesaboj\u0101 datoru, un j\u0101pavada stundas, m\u0113\u0123inot noskaidrot, k\u0101 t\u0101 darbojas, iesp\u0113jams, izmantojot programm\u0113\u0161anu. C\u012b\u0146a ar programm\u0101m, kas ir sare\u017e\u0123\u012btas, neintuit\u012bvas un bie\u017ei vien prasa licenci.<\/p>\n\n\n\n

Risin\u0101jums ir, un to sauc par Prote\u012bnu att\u0113lveidot\u0101js<\/a>!<\/p>\n\n\n\n

\n
Efekt\u012bvu zin\u0101tnisko fig\u016bru izveide da\u017eu min\u016b\u0161u laik\u0101<\/a><\/div>\n<\/div>\n\n\n\n

Par Protein Imager<\/strong><\/h2>\n\n\n\n

Prote\u012bnu att\u0113lveidot\u0101js<\/a> ir bezmaksas t\u012bmek\u013ca molekul\u0101ro att\u0113lu p\u0101rl\u016bks, kas ar da\u017eiem klik\u0161\u0137iem \u013cauj izveidot molekul\u0101r\u0101s ilustr\u0101cijas. To izstr\u0101d\u0101ju\u0161i zin\u0101tnieki no 3D prote\u012bnu att\u0113lveido\u0161anas studija<\/a> ar m\u0113r\u0137i racionaliz\u0113t prote\u012bnu ilustr\u0101ciju.<\/p>\n\n\n\n

K\u0101p\u0113c Protein Imager?<\/strong><\/h2>\n\n\n\n

Protein Imager at\u0161\u0137iras no citiem molekul\u0101rajiem mekl\u0113t\u0101jiem ar savu vienk\u0101r\u0161\u012bbu un pieejam\u012bbu. Lai piek\u013c\u016btu vis\u0101m Protein Imager funkcij\u0101m, jums tikai j\u0101piesak\u0101s, izmantojot savu e-pastu un interneta savienojumu.<\/p>\n\n\n\n

Protein Imager ir lietot\u0101jam draudz\u012bgs interfeiss, kas \u013cauj piel\u0101got molekul\u0101ro ilustr\u0101ciju ar vis\u0101m deta\u013c\u0101m. Lietot\u0101js var izv\u0113l\u0113ties no da\u017e\u0101diem iepriek\u0161 iestat\u012btiem stiliem (karikat\u016brisks, re\u0101listisks, rupjgraudaina virsma) vai piel\u0101got vizualiz\u0101ciju p\u0113c saviem ieskatiem.<\/p>\n\n\n\n

\"\"<\/a>
Iepriek\u0161 iestat\u012bto stilu piem\u0113ri, ko var izmantot Protein Imager.<\/figcaption><\/figure>\n\n\n\n

Molekulu att\u0113li (virsmas, karikat\u016bra, sf\u0113ras, n\u016bji\u0146as utt.), kr\u0101so\u0161anas re\u017e\u012bmi, fona kr\u0101sas, \u0113nojums un apk\u0101rt\u0113j\u0101s vides okl\u016bzija ir tikai da\u017ei no piel\u0101gojamiem parametriem, ar kuriem lietot\u0101ji var sp\u0113l\u0113ties.<\/p>\n\n\n\n

\"\"\/<\/a><\/figure>\n\n\n\n

Ekspertiem ir pieejami ar\u012b t\u0101di datu anal\u012bzes r\u012bki k\u0101 strukt\u016bru superpoz\u012bcija, sekven\u010du skat\u012bt\u0101js un atlases.<\/p>\n\n\n\n

Turkl\u0101t tas ir piln\u012bb\u0101 pieejams tie\u0161saist\u0113, kas noz\u012bm\u0113, ka nav nepiecie\u0161ama lok\u0101la instal\u0113\u0161ana, nav j\u0101str\u0101d\u0101 ar novecoju\u0161\u0101m versij\u0101m un nav j\u0101saskaras ar savietojam\u012bbas probl\u0113m\u0101m ar oper\u0113t\u0101jsist\u0113m\u0101m. Katra atveido\u0161ana ir atkar\u012bga no \u012bpa\u0161a servera, un atveido\u0161anas laiks parasti ir maz\u0101ks par 1 min\u016bti atkar\u012bb\u0101 no ilustr\u0101cijas sare\u017e\u0123\u012bt\u012bbas.<\/p>\n\n\n\n

\n
S\u0101ciet veidot Mind the Graph jau tagad<\/a><\/div>\n<\/div>\n\n\n\n

Kas izmanto Protein Imager?<\/strong><\/h2>\n\n\n\n

Protein Imager ir tik vienk\u0101r\u0161s un intuit\u012bvs, ka to var izmantot ikviens, s\u0101kot no bakalaura l\u012bdz pat pieredz\u0113ju\u0161iem zin\u0101tniekiem. Lietot\u0101ji var br\u012bvi izpaust savu rado\u0161umu un veidot zin\u0101tniskas ilustr\u0101cijas da\u017e\u0101diem m\u0113r\u0137iem. <\/p>\n\n\n\n

Daudzi zin\u0101tnieki izmanto Protein Imager, lai ilustr\u0113tu savus p\u0113t\u012bjumu rezult\u0101tus savos darbos vai grafiskos kopsavilkumos. <\/p>\n\n\n\n

\"\"<\/a><\/figure>\n\n\n\n

Prote\u012bnu att\u0113lveidot\u0101js, ko izmanto zin\u0101tnieks Matteo Oliverio<\/a> lai izveidotu grafiskus abstraktus.<\/p>\n\n\n\n

Rado\u0161\u0101kie no vi\u0146iem izstr\u0101d\u0101 \u017eurn\u0101lu v\u0101kus, izmantojot programmu Protein Imager. Tie, kas aizraujas ar zin\u0101tnes komunik\u0101ciju, izmanto Protein Imager, lai rad\u012btu pievilc\u012bgus vizu\u0101lus soci\u0101lo mediju zi\u0146\u0101m.<\/p>\n\n\n\n

\"\"<\/a><\/figure>\n\n\n\n

Oksfordas Universit\u0101tes profesore Syma Khalid izstr\u0101d\u0101ja dizainu \u017eurn\u0101la \"Structure\" 29. s\u0113juma 5. numura 2021. gada maija v\u0101kam.<\/a>.<\/p>\n\n\n\n

Visbeidzot, Protein Imager ir iesp\u0113ja eksport\u0113t molekulas k\u0101 tilpuma failus (VRML2 form\u0101t\u0101), ko izmanto medic\u012bnas ilustratori 3D grafikas programm\u0101s, piem\u0113ram, Blender, Cinema 4D, Maya.<\/p>\n\n\n\n

\"\"<\/a><\/figure>\n\n\n\n

Att\u0113ls no BioSciVisuals zin\u0101tnisk\u0101s ilustr\u0101cijas studijas portfolio.<\/a> Lai ilustr\u0113tu gal\u012bgaj\u0101 plak\u0101ta grafik\u0101 iek\u013caut\u0101s molekulas, l\u012bdztekus profesion\u0101liem ilustr\u0113\u0161anas r\u012bkiem tika izmantots Protein Imager.<\/p>\n\n\n\n

\n
Vai esat gatavs s\u0101kt str\u0101d\u0101t ar Mind the Graph?<\/a><\/div>\n<\/div>\n\n\n\n

Ilustr\u0101ciju uzs\u0101k\u0161ana<\/strong><\/h2>\n\n\n\n

Apskat\u012bsim galvenos so\u013cus, lai s\u0101ktu savu ilustr\u0113\u0161anas ce\u013cojumu, vai ne?<\/p>\n\n\n\n

1 - iel\u0101d\u0113jiet molekul\u0101ro strukt\u016bru<\/h3>\n\n\n\n

Iet uz Prote\u012bnu att\u0113lveidot\u0101js<\/a> un aug\u0161upiel\u0101d\u0113t jebkuru molekul\u0101ro strukt\u016bru no sava datora vai ieg\u016bt to no biolo\u0123iskaj\u0101m datub\u0101z\u0113m, piem\u0113ram, Prote\u012bnu datu bankas vai datub\u0101zes Orientations of Proteins in Membranes (OPM).<\/p>\n\n\n\n

\"\"<\/a><\/figure>\n\n\n\n

2 - Piel\u0101go\u0161ana<\/h3>\n\n\n\n

Izmantojot strukt\u016bras paneli labaj\u0101 pus\u0113, izv\u0113lieties molekul\u0101ro att\u0113lojumu un kr\u0101su sh\u0113mas, vizualiz\u0101cijas pane\u013cos piel\u0101gojiet \u0113nojumu, apgaismojumu, apk\u0101rt\u0113j\u0101s vides okl\u016bziju, vienk\u0101r\u0161i izv\u0113lieties iepriek\u0161 iestat\u012btu stilu.<\/p>\n\n\n\n

\"\"<\/a><\/figure>\n\n\n\n

3 - Ieg\u016bstiet att\u0113lu<\/h3>\n\n\n\n

Kad esat apmierin\u0101ts ar konstrukcijas izskatu, pieprasiet t\u0101s atveidi.<\/p>\n\n\n\n

P\u0113c da\u017e\u0101m min\u016bt\u0113m no render\u0113\u0161anas pane\u013ca var\u0113siet lejupiel\u0101d\u0113t ilustr\u0101ciju augst\u0101 kvalit\u0101t\u0113. \u0145emiet v\u0113r\u0101, ka, lai piepras\u012btu render\u0113\u0161anu, jums j\u0101re\u0123istr\u0113jas, nor\u0101dot der\u012bgu e-pasta adresi.<\/p>\n\n\n\n

\"\"<\/a><\/figure>\n\n\n\n

4 - Kop\u012bgojiet to ar saviem sadarb\u012bbas partneriem<\/h3>\n\n\n\n

Kad esat apmierin\u0101ts ar savu darbu, varat to saglab\u0101t lietot\u0101ja map\u0113, kur\u0101 var saglab\u0101t l\u012bdz 25 MB. Katram projektam varat izveidot saiti, lai to var\u0113tu kop\u012bgot ar sadarb\u012bbas partneriem un visi b\u016btu vienkopus.<\/p>\n\n\n\n

\"\"<\/a><\/figure>\n\n\n\n
\n
S\u0101ciet lietot Mind The Graph tie\u0161i tagad bez maksas!<\/a><\/div>\n<\/div>\n\n\n\n

Mind the Graph un 3D prote\u012bnu att\u0113lveido\u0161ana<\/strong><\/h2>\n\n\n\n

Protams, 3D Protein Imaging un Mind the Graph veido vislab\u0101ko partner\u012bbu! <\/p>\n\n\n\n

Varat izmantot savu 3D olbaltumvielas att\u0113lu un p\u0113c sekundes to aug\u0161upiel\u0101d\u0113t sav\u0101 rad\u012bjum\u0101 vietn\u0113 Mind the Graph. Lai uzzin\u0101tu, k\u0101 aug\u0161upiel\u0101d\u0113t att\u0113lus, varat noskat\u012bties m\u0101c\u012bbu videoklipu. tie\u0161i \u0161eit<\/a>. <\/p>\n\n\n\n

Vai ar\u012b dodieties uz savu Mind the Graph izveidi, noklik\u0161\u0137iniet uz Vair\u0101k<\/strong> kreis\u0101s izv\u0113lnes apak\u0161\u0101, p\u0113c tam Aug\u0161upiel\u0101d\u0113t<\/strong>, izv\u0113lieties att\u0113lu un p\u0113c iel\u0101des izv\u0113lieties un velciet att\u0113lu uz darbvietu, un viss! <\/p>\n\n\n\n

Turkl\u0101t varat izv\u0113l\u0113ties jebkuru Mind the Graph galerij\u0101 pieejamo ilustr\u0101ciju, lai to izmantotu kop\u0101 ar saviem prote\u012bnu att\u0113liem. <\/p>\n\n\n\n

Mind the Graph galerij\u0101 ir daudz vizu\u0101li pievilc\u012bgu skait\u013cu j\u016bsu p\u0113t\u012bjumiem - vair\u0101k nek\u0101 40 000 zin\u0101tniski prec\u012bzu ilustr\u0101ciju vair\u0101k nek\u0101 80 popul\u0101r\u0101s jom\u0101s. Ja jums nepiecie\u0161ama ilustr\u0101cija, j\u016bs to atrad\u012bsiet Mind the Graph. <\/p>\n\n\n\n

Tom\u0113r, ja neesat atradis to, kas jums nepiecie\u0161ams, vai ja jums nepiecie\u0161ama \u013coti specifiska ilustr\u0101cija, varat piepras\u012bt personaliz\u0113tu ilustr\u0101ciju, un Mind the Graph ilustr\u0101ciju komanda to izstr\u0101d\u0101s j\u016bsu viet\u0101. Viss, kas jums j\u0101dara, ir j\u0101aizpilda Mind the Graph Piepras\u012bt ikonu<\/strong> veidlapas iek\u0161pus\u0113 sav\u0101 darbviet\u0101, pievienojot \u012bsu paskaidrojumu un atsauces att\u0113lu. Ned\u0113\u013cas laik\u0101 j\u016bs sa\u0146emsiet personaliz\u0113tu ilustr\u0101ciju. <\/p>\n\n\n\n

Apbr\u012bnojami, vai ne? <\/p>\n\n\n\n

Skatiet videoklipu par to, k\u0101 varat izveidot savu zin\u0101tnisko fig\u016bru, izmantojot Mind the Graph un izmantojot \u0101r\u0113jos att\u0113lus no 3D prote\u012bnu att\u0113lveido\u0161anas.<\/p>\n\n\n\n

\n