{"id":10972,"date":"2020-03-20T08:22:00","date_gmt":"2020-03-20T11:22:00","guid":{"rendered":"https:\/\/blog.mindthegraph.com\/?p=10972"},"modified":"2022-10-18T08:09:52","modified_gmt":"2022-10-18T11:09:52","slug":"coronavirus-covid-19-is-hydroxychloroquine-the-new-hope-apparently-yes","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/lv\/coronavirus-covid-19-is-hidroksihlorohin-jauna-ceriba-acimredzot-ja\/","title":{"rendered":"Koronav\u012bruss (Covid-19): vai hidroksihlorhin\u012bns ir jaun\u0101 cer\u012bba? Ac\u012bmredzot j\u0101."},"content":{"rendered":"

Divi neseni dokumenti, kuros apkopots viens in vitro p\u0113t\u012bjums un neliela m\u0113roga kl\u012bnisks p\u0113t\u012bjums, bija pietiekami, lai Donalds Tramps liktu FDA ieviest jaunu z\u0101\u013cu kl\u012bnisko indik\u0101ciju hidroksihlorokv\u012bnam: uzlabot koronav\u012brusa (Covid-19) skarto pacientu simptomus.<\/p>\n

\u0160is, iesp\u0113jams, ir vis\u0101tr\u0101kais z\u0101\u013cu apstiprin\u0101\u0161anas process m\u016bsdienu v\u0113stur\u0113, un prezidentam ac\u012bmredzot ir taisn\u012bba. P\u0101rsteidzo\u0161i, ja runa ir par pasaules l\u012bderi, kuram nav lielas simp\u0101tijas pret zin\u0101tni.<\/p>\n

\"\"<\/p>\n

Pirmie pier\u0101d\u012bjumi par hidroksihlorhikv\u012bna ietekmi uz v\u012brusu n\u0101ca no \u0161is raksts public\u0113ts vakar par Cell Discovery<\/a>Tas ir tikai in vitro p\u0113t\u012bjums ar visiem ierobe\u017eojumiem, ta\u010du tas skaidri par\u0101da z\u0101\u013cu potenci\u0101lu nogalin\u0101t v\u012brusu. Kad vi\u0146i iesniedza \u0161o darbu, \u0136\u012bn\u0101 bija apstiprin\u0101ti 80 000 saslim\u0161anas gad\u012bjumu, tostarp 2946 n\u0101ves gad\u012bjumi, k\u0101 ar\u012b vair\u0101k nek\u0101 10 566 apstiprin\u0101ti gad\u012bjumi 72 cit\u0101s valst\u012bs. Taj\u0101 laik\u0101 liel\u0101k\u0101s cer\u012bbas tika liktas uz medikamentu, ko sauca par remdesiviru.<\/p>\n

\"hidrohlorkv\u012bna
In vitro hidrohlorkv\u012bna iedarb\u012bba uz koronav\u012brusu (Covid-19). Kolonna labaj\u0101 pus\u0113 r\u0101da efekt\u012bvo z\u0101\u013cu iedarb\u012bbu sal\u012bdzin\u0101jum\u0101 ar hlorhikv\u012bna vai kontroles grupas iedarb\u012bbu kreisaj\u0101 pus\u0113. Tas par\u0101da, ka z\u0101les uzlaboja \u0161\u016bnu sp\u0113ju izspiest v\u012brusus... tas ir t\u0101pat k\u0101 pal\u012bdz\u0113t izraid\u012bt nev\u0113lamu kaimi\u0146u no m\u0101jas. Tas pal\u012bdz! \ud83d\ude42 <\/figcaption><\/figure>\n

Ta\u010du visliel\u0101k\u0101s zi\u0146as n\u0101ca no neliela apjoma kl\u012bnisk\u0101 p\u0113t\u012bjuma, kas public\u0113ts iepriek\u0161\u0113j\u0101 dien\u0101. Nosaukums ir Hidroksihlorhin\u012bns un azitromic\u012bns k\u0101 COVID-19 \u0101rst\u0113\u0161anas l\u012bdzeklis: atkl\u0101ta, nerandomiz\u0113ta kl\u012bnisk\u0101 p\u0113t\u012bjuma rezult\u0101ti, un tos var lejupiel\u0101d\u0113t \"in press\" versij\u0101.<\/a><\/p>\n

P\u0113t\u012bjum\u0101, kur\u0101 piedal\u012bj\u0101s tikai 20 pacienti, autori pier\u0101d\u012bja, ka hidroksihlorhin\u012bns ir efekt\u012bvs pret koronav\u012brusa Covid-19 infekciju. Paties\u012bb\u0101 tas samazin\u0101ja infic\u0113to personu 75% 6 dienu laik\u0101, kas ir satrieco\u0161i. V\u0113l lab\u0101k par to bija tas, ka kombin\u0101cija ar azitromic\u012bnu uzlaboja \u0101rst\u0113\u0161anas efektivit\u0101ti l\u012bdz 95%.<\/p>\n

\"Hidrohihlorhlorh\u012bna
Hidrohihlorhlorh\u012bna un azitromic\u012bna kombin\u0113t\u0101 terapija ir efekt\u012bva pret koronav\u012brusa (Covid-19) infekcij\u0101m cilv\u0113kiem. \u0160is samazin\u0101jums ir dramatisks un dod jaunu cer\u012bbu skartajiem pacientiem.<\/figcaption><\/figure>\n

\u0100rst\u0113\u0161ana uzlaboja simptomus, vienlaikus samazinot ar\u012b v\u012brusa slodzi pacientiem. \u0160\u012bs z\u0101les jau iepriek\u0161 ir apstiprin\u0101tas mal\u0101rijas \u0101rst\u0113\u0161anai, kas noz\u012bm\u0113, ka t\u0101s tiek uzskat\u012btas par dro\u0161\u0101m. \"M\u0101sas\" z\u0101les hlorokv\u012bns bija maz\u0101k efekt\u012bvas. Labi mums, jo tas ir algo toksisk\u0101ks.<\/p>\n

P\u0113t\u012bjums nebija randomiz\u0113ts, un tas ir neliela m\u0113roga p\u0113t\u012bjums, tom\u0113r \u0161\u0137iet, ka, lai gan epid\u0113mija s\u0101k\u0101s \u0136\u012bn\u0101, risin\u0101jums ir glob\u0101las kopienas centieni. In vitro dokuments faktiski ir \u0137\u012bnie\u0161u, bet kl\u012bniskais - Eiropas, prec\u012bz\u0101k, Francijas. Interesanti, ka s\u0101kotn\u0113j\u0101 z\u0101\u013cu re\u0123istr\u0101cija hidroksihlorokv\u012bnam ir no Francijas farm\u0101cijas uz\u0146\u0113muma Sanofi, un nesenais kl\u012bniskais p\u0113t\u012bjums tika veikts Marse\u013c\u0101. Ale le bleu!<\/p>\n

Medscape ir lielisks raksts par to tiem, kurus interes\u0113 s\u012bk\u0101ka inform\u0101cija.<\/a><\/p>\n

L\u016bdzu, cit\u0113jiet \u0161o darbu k\u0101 Gautret et al. (2020) Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial. International Journal of Antimicrobial Agents - In Press 2020. gada 17. marts - DOI : 10.1016\/j.ijantimicag.2020.105949.<\/p>","protected":false},"excerpt":{"rendered":"","protected":false},"author":4,"featured_media":11134,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[419,959,28],"tags":[400,394,396,388,389,398,397,399,92,53,554,395,250,393],"yoast_head":"\nCoronavirus Covid-19: hydroxychloroquine, the new hope?<\/title>\n<meta name=\"description\" content=\"Hydroxycholoquine is the new hope for coronavirus (Covid-19) infection. 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