{"id":9012,"date":"2019-06-03T11:07:17","date_gmt":"2019-06-03T14:07:17","guid":{"rendered":"https:\/\/blog.mindthegraph.com\/?p=9012"},"modified":"2022-10-18T08:23:58","modified_gmt":"2022-10-18T11:23:58","slug":"award-zika-virus-infection","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/lt\/apdovanojimas-zika-virusine-infekcija\/","title":{"rendered":"Zikos virusas: Apdovanotas tyrimas, kuris naujai atskleid\u017eia ilgalaikes pasekmes"},"content":{"rendered":"

Visada nuostabu parodyti m\u016bs\u0173 naudotoj\u0173 mokslin\u012f darb\u0105. Taigi \u0161iandien pristatysiu jums Brazilijos mokslinink\u0119 Isis de Souza ir jos darb\u0105 su zikos virusu. Isis ir jos kolegos tiria ankstyvos Zikos viruso infekcijos poveik\u012f pel\u0117ms. Ji taip pat yra \"Mind the graph\" naudotoja, o nugal\u0117tojos pristatyme yra vaizdini\u0173 i\u0161tekli\u0173 i\u0161 \"Mind the graph\". Na, negal\u0117jome labiau did\u017eiuotis.<\/p>\n

Kas yra zikos virusas?<\/strong><\/h3>\n

Zikos virusas priklauso Flaviviridae \u0161eimai. \u0160iai grupei priklauso keletas patogenini\u0173 virus\u0173. Labiausiai \u017einomas yra geltonosios kar\u0161tin\u0117s virusas, kuris yra \u0161ios \u0161eimos tipinis virusas ir taip pat yra \u0161eimos pavadinimo prie\u017eastis, nes \u017eodis flavus lotyni\u0161kai rei\u0161kia \"geltonas\". Be to, kiti flavivirusai yra Vakar\u0173 Nilo virusas, Deng\u0117 virusas ir erkinio encefalito virusas.<\/p>\n

Flaviviridae \u0161eimos virusams b\u016bdingas bendras dydis (40-65 nm) ir virus\u0173 apvalkalai, kurie dengia j\u0173 apsaugin\u0119 ikosaedrin\u0119 nukleokapsid\u0119. Be to, j\u0173 genetin\u0117 med\u017eiaga yra RNR ir jie matomi elektroniniame mikroskope.<\/p>\n

Toliau pateiktame infografike parodyta pagrindin\u0117 zikos viruso strukt\u016bra:<\/p>\n

\"Per\u017ei\u016bra_90481\"<\/a><\/p>\n

 Zikos virus\u0105 pirmiausia platina moteri\u0161kos lyties Stegomya aegypti<\/em> uodai, kuriems reikia kraujo, kad gal\u0117t\u0173 d\u0117ti kiau\u0161in\u0117lius. Uodai aktyv\u016bs daugiausia dien\u0105.<\/p>\n

Nugal\u0117tojo popierius<\/strong><\/h2>\n

Pastaruoju metu daugelis mokslinink\u0173 tiria neurologinius sutrikimus, susijusius su \u012fgimtu zikos viruso (ZIKV) poveikiu.<\/p>\n

Be to, \u012fgimta mikrocefalija yra vienas ry\u0161kiausi\u0173 rei\u0161kini\u0173, apie kuriuos prane\u0161ta ZIKV u\u017esikr\u0117tusiems naujagimiams. D\u0117l \u0161ios prie\u017easties moksliniai tyrimai sutelkti \u012f ZIKV sukeliamos \u012fgimtos mikrocefalijos mechanizm\u0173 supratim\u0105.<\/p>\n

Ta\u010diau tik 1-13% veikiam\u0173 vaisi\u0173 gimimo metu pasirei\u0161kia fizini\u0173 apsigimim\u0173. Be to, tr\u016bksta informacijos apie ilgalaikes perinatalin\u0117s infekcijos pasekmes.<\/p>\n

Taigi, Isis de Souza ir jos kolegos naudojo peles, kad i\u0161tirt\u0173 elgesio ir neuropatologines s\u0105lygas bei trumpalaikes ir ilgalaikes pasekmes, o rezultatus paskelb\u0117 straipsnyje, pavadintame \u016amin\u0117s ir l\u0117tin\u0117s neurologin\u0117s ankstyvos Zikos viruso infekcijos pasekm\u0117s pel\u0117ms.<\/strong><\/p>\n

\u017dmon\u0117ms yra daug klinikini\u0173 b\u016bkli\u0173, susijusi\u0173 su Zikos viruso poveikiu, kurios pasirei\u0161kia pra\u0117jus keliems m\u0117nesiams ar metams po gimimo. Taigi, net jei k\u016bdikiai negimsta su mikrocefalija, jiems gali pasireik\u0161ti motorikos sutrikimai, \u017eiev\u0117s displazija, susijusi su traukuliais, ir kiti neurologiniai sutrikimai.<\/p>\n

Pasak autori\u0173, jie \"sistemi\u0161kai u\u017ekr\u0117t\u0117 naujagimius laukinio tipo peles ZIKV ir atliko ilgalaik\u012f elgesio, neuropatologini\u0173 ir molekulini\u0173 infekcijos pasekmi\u0173 steb\u0117jim\u0105. Prane\u0161ame apie trumpalaikes ir ilgalaikes komplikacijas po ZIKV infekcijos pel\u0117ms ir parodome, kad ankstyva naviko nekroz\u0117s faktoriaus-\u03b1 (TNF-\u03b1) neutralizacija i\u0161 dalies u\u017ekerta keli\u0105 \u0161iems \u017ealingiems padariniams. M\u016bs\u0173 i\u0161vados atskleid\u017eia, kad reikia skirti ypating\u0105 d\u0117mes\u012f galimai neuropatologini\u0173 komplikacij\u0173 na\u0161tai vaikams ir paaugliams po \u012fgimto ZIKV poveikio, ir rodo, kad ankstyvas neurou\u017edegimo slopinimas gali b\u016bti potencialus gydymo b\u016bdas siekiant i\u0161vengti ilgalaiki\u0173 neurologini\u0173 pasekmi\u0173 ZIKV u\u017esikr\u0117tusiems k\u016bdikiams.\"<\/em><\/p>\n

 \"GE Healthcare Life Sciences\" skatinamas apdovanojimas<\/strong><\/h2>\n

\"Pr\u00eamio Jovem Talento em Ci\u00eancias da Vida\", arba Jaun\u0173j\u0173 talent\u0173 apdovanojim\u0105 gyvyb\u0117s moksl\u0173 srityje, skatina Brazilijos biochemijos ir molekulin\u0117s biologijos draugija ir \"GE Healthcare Life Sciences\". Mokslinis komitetas atrinko penkis kandidatus, kurie pristatys savo darbus metiniame kongrese - renginyje, kuriame dalyvauja d\u0117stytojai ir studentai i\u0161 visos Lotyn\u0173 Amerikos.<\/p>\n

Komitetas i\u0161rinko Isis de Oliveira, kuri pristat\u0117 savo tyrim\u0105 apie zikos viruso poveikio pasekmes.<\/p>\n

\"mokslinis
Isis de Oliveira pristato savo rezultatus<\/figcaption><\/figure>\n

Ji para\u0161\u0117 prane\u0161im\u0105, kuriame d\u0117kojo savo universitetui ir stipendijai, suteikusiai galimyb\u0119 studijuoti. Be to, ji i\u0161rei\u0161k\u0117 vilt\u012f, kad ateities kartai bus suteikta galimyb\u0117 siekti mokslin\u0117s karjeros, kaip ir jai.<\/p>\n

Taigi, norime pasveikinti Isis su jos nuostabiu darbu! Tikiuosi, kad savo darbu ji \u012fkv\u0117ps daugiau \u017emoni\u0173 tapti mokslininkais.<\/p>\n

Jei norite vaizdingiau pateikti duomenis, kad gal\u0117tum\u0117te geriau bendrauti mokslo srityje, galite i\u0161bandyti Mind the Graph:<\/p>\n

\"nepamir\u0161kite<\/a><\/p>","protected":false},"excerpt":{"rendered":"

Visada nuostabu parodyti m\u016bs\u0173 naudotoj\u0173 mokslin\u012f darb\u0105. Taigi \u0161iandien pristatysiu jums Brazilijos mokslinink\u0119 Isis de Souza ir jos darb\u0105 su zikos virusu. Isis ir jos kolegos tiria ankstyvos Zikos viruso infekcijos poveik\u012f pel\u0117ms. Ji taip pat yra \"mind the graph\" naudotoja, o laim\u0117tojos pristatymas buvo [...]<\/p>","protected":false},"author":11,"featured_media":9080,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"image","meta":[],"categories":[40],"tags":[299,282,554,71,775,293,316,315],"yoast_head":"\nZika virus: the award-winning study that sheds light on the future<\/title>\n<meta name=\"description\" content=\"Microcephaly is a known effect related to congenital exposure to zika virus. 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