{"id":16630,"date":"2022-09-08T18:14:00","date_gmt":"2022-09-08T21:14:00","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/success-case-zika-virus-replicates-in-adult-human-brain-tissue-and-impairs-synapses-and-memory-in-mice-copy\/"},"modified":"2023-03-17T14:47:54","modified_gmt":"2023-03-17T17:47:54","slug":"success-case-igh-resolution-synchrotron-based-x-ray-microtomography-as-a-tool-to-unveil-the-three-dimensional-neuronal-architecture-of-the-brain","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/lt\/sekmingas-dideles-skiriamosios-gebos-sinchrotrono-rentgeno-spinduliu-mikrotomografijos-kaip-irankio-smegenu-trimates-neuronu-architekturos-atskleidimui-pavyzdys\/","title":{"rendered":"Didel\u0117s skiriamosios gebos sinchrotronu pagr\u012fsta rentgeno spinduli\u0173 mikrotomografija - priemon\u0117 atskleisti trimat\u0119 smegen\u0173 neuron\u0173 architekt\u016br\u0105 Dokumento ap\u017evalga"},"content":{"rendered":"

Rentgeno spinduli\u0173 mikrotomografija tapo nauju metodu smegen\u0173 citoarchitekt\u016brai ir jungtims i\u0161\u0161ifruoti, o \u010dia pateikiame metod\u0105, skirt\u0105 i\u0161tisiems neuronams vaizduoti.<\/p>\n\n\n\n

Didel\u0117s skiriamosios gebos sinchrotronu pagr\u012fsta rentgeno spinduli\u0173 mikrotomografija - priemon\u0117 atskleisti trimat\u0119 smegen\u0173 neuron\u0173 architekt\u016br\u0105<\/strong><\/h2>\n\n\n\n

Straipsnyje \"Didel\u0117s skiriamosios gebos sinchrotronu pagr\u012fsta rentgeno spinduli\u0173 mikrotomografija kaip priemon\u0117 atskleisti trimat\u0119 smegen\u0173 neuron\u0173 architekt\u016br\u0105\" Matheusas de Castro Fonseca ir kiti (2018) pa\u017eym\u0117jo, kad neuron\u0173, kaip individualizuot\u0173 vienet\u0173, tyrimai prasid\u0117jo XIX a., suk\u016brus neuron\u0173 doktrin\u0105. <\/p>\n\n\n\n

Pastaraisiais metais dedama daug pastang\u0173, kad b\u016bt\u0173 galima suprasti neuron\u0173 organizacij\u0105 ir ry\u0161\u012f nepa\u017eeistuose smegen\u0173 m\u0117giniuose. Golgio-Kokso \u017eenklinimo metodas suteikia tinkam\u0105 kontrast\u0105 specifiniam neuron\u0173 \u017eenklinimui rentgeno spinduli\u0173 mikrotomografijoje. <\/p>\n\n\n\n

Neuronai pasi\u017eymi savita morfologija ir specifiniais jung\u010di\u0173 modeliais, kurie yra b\u016btini j\u0173 tinkamam funkcionavimui. Tyr\u0117jai pristato vaizdavimo metod\u0105, kuriame sinchrotronu pagr\u012fsta rentgeno spinduli\u0173 mikrotomografija derinama su Golgio-Kokso impregnavimo protokolu. <\/p>\n\n\n\n

Taikant \u0161\u012f metod\u0105 galima gauti didesn\u012f ir homogeni\u0161kesn\u012f palyginti retai audinyje pasiskirs\u010diusi\u0173 neuron\u0173 kontrast\u0105.<\/p>\n\n\n\n

Smegenys 14 dien\u0173 buvo inkubuojamos nuo \u0161viesos apsaugotame Golgi-Cox da\u017eymo tirpale. Po inkubacijos laikotarpio smegenys buvo serijiniu b\u016bdu pjaustomos vibratomu.<\/strong><\/p>\n\n\n\n

Patikrinkite originalus straipsnis \u010dia<\/a>.<\/p>\n\n\n\n

Grafinis abstraktas, paremtas Mind the Graph<\/strong><\/h2>\n\n\n\n
<\/div>\n\n\n
\n
\"\"<\/a>
Pagaminta i\u0161 Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n

Autorius naudojo Mind the Graph<\/a> sukurti schematin\u0119 iliustracij\u0105, vaizduojan\u010di\u0105 suaugusias peles, kurioms i.p. \u0161virk\u0161\u010diama fiziologinio tirpalo arba pilokarpino tirpalo (280 mg\/kg). Sud\u0117ting\u0173 proces\u0173 atvaizdavimas infografikoje yra geras b\u016bdas padaryti juos lengvai suprantamus, nepaliekant nuo\u0161alyje detali\u0173 ir esmin\u0117s informacijos.<\/p>\n\n\n\n

Atrodo, kad kai kurie tyr\u0117j\u0173 rezultatai patvirtina tai, kas apie \u0161i\u0105 srit\u012f buvo \u017einoma anks\u010diau: de Castro Fonseca teig\u0117, kad \"gyvsidabrio pagrindu atliktas neuron\u0173 impregnavimas leido mums ai\u0161kiai apibr\u0117\u017eti i\u0161tisus neuronus daugiausia d\u0117l to, kad l\u0105stel\u0117s buvo impregnuotos i\u0161tisiau ir homogeni\u0161kiau, o artefakt\u0173 tankis buvo daug ma\u017eesnis\".<\/p>\n\n\n\n

Dokument\u0173 poveikis ir na\u0161umas<\/strong><\/h2>\n\n\n\n

Galime analizuoti su Altmetric<\/a> duomen\u0173, kad \u0161io dokumento d\u0117mesio internete balas yra didesnis nei 64%<\/strong><\/strong> vis\u0173 kit\u0173 pana\u0161aus am\u017eiaus straipsni\u0173 \u017eurnale \"Scientific Reports\".<\/strong><\/p>\n\n\n\n

<\/div>\n\n\n
\n
\"\"<\/a>
\u0160altinis Altmetrika<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n

Pagerinkite savo straipsnio prieinamum\u0105 naudodami infografik\u0105.<\/p>\n\n\n\n

\n
I\u0161bandykite Mind the Graph<\/strong><\/a><\/div>\n<\/div>\n\n\n\n
<\/div>","protected":false},"excerpt":{"rendered":"

Susipa\u017einkite su naujuoju smegen\u0173 citoarchitekt\u016bros ir jung\u010di\u0173 i\u0161\u0161ifravimo metodu, pavaizduotu Mind the Graph iliustracijose.<\/p>","protected":false},"author":29,"featured_media":20013,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[195,958,957,960,1],"tags":[96,554,775,963],"yoast_head":"\nHigh-resolution synchrotron-based X-ray microtomography as a tool to unveil the three-dimensional neuronal architecture of the brain Paper Review - Mind the Graph Blog<\/title>\n<meta name=\"description\" content=\"Look into the new method for deciphering the cytoarchitecture and connectivity of the brain represented with Mind the Graph's illustrations.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mindthegraph.com\/blog\/lt\/sekmingas-dideles-skiriamosios-gebos-sinchrotrono-rentgeno-spinduliu-mikrotomografijos-kaip-irankio-smegenu-trimates-neuronu-architekturos-atskleidimui-pavyzdys\/\" \/>\n<meta property=\"og:locale\" content=\"lt_LT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"High-resolution synchrotron-based X-ray microtomography as a tool to unveil the three-dimensional neuronal architecture of the brain Paper Review - Mind the Graph Blog\" \/>\n<meta property=\"og:description\" content=\"Look into the new method for deciphering the cytoarchitecture and connectivity of the brain represented with Mind the Graph's illustrations.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/mindthegraph.com\/blog\/lt\/sekmingas-dideles-skiriamosios-gebos-sinchrotrono-rentgeno-spinduliu-mikrotomografijos-kaip-irankio-smegenu-trimates-neuronu-architekturos-atskleidimui-pavyzdys\/\" \/>\n<meta property=\"og:site_name\" content=\"Mind the Graph Blog\" \/>\n<meta property=\"article:published_time\" content=\"2022-09-08T21:14:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-03-17T17:47:54+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/blog_2.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1125\" \/>\n\t<meta property=\"og:image:height\" content=\"614\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Artur Zignani\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:image\" content=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/blog_2.jpg\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Artur Zignani\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"High-resolution synchrotron-based X-ray microtomography as a tool to unveil the three-dimensional neuronal architecture of the brain Paper Review - Mind the Graph Blog","description":"Look into the new method for deciphering the cytoarchitecture and connectivity of the brain represented with Mind the Graph's illustrations.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/mindthegraph.com\/blog\/lt\/sekmingas-dideles-skiriamosios-gebos-sinchrotrono-rentgeno-spinduliu-mikrotomografijos-kaip-irankio-smegenu-trimates-neuronu-architekturos-atskleidimui-pavyzdys\/","og_locale":"lt_LT","og_type":"article","og_title":"High-resolution synchrotron-based X-ray microtomography as a tool to unveil the three-dimensional neuronal architecture of the brain Paper Review - Mind the Graph Blog","og_description":"Look into the new method for deciphering the cytoarchitecture and connectivity of the brain represented with Mind the Graph's illustrations.","og_url":"https:\/\/mindthegraph.com\/blog\/lt\/sekmingas-dideles-skiriamosios-gebos-sinchrotrono-rentgeno-spinduliu-mikrotomografijos-kaip-irankio-smegenu-trimates-neuronu-architekturos-atskleidimui-pavyzdys\/","og_site_name":"Mind the Graph Blog","article_published_time":"2022-09-08T21:14:00+00:00","article_modified_time":"2023-03-17T17:47:54+00:00","og_image":[{"width":1125,"height":614,"url":"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/blog_2.jpg","type":"image\/jpeg"}],"author":"Artur Zignani","twitter_card":"summary_large_image","twitter_image":"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/blog_2.jpg","twitter_misc":{"Written by":"Artur Zignani","Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/mindthegraph.com\/blog\/success-case-igh-resolution-synchrotron-based-x-ray-microtomography-as-a-tool-to-unveil-the-three-dimensional-neuronal-architecture-of-the-brain\/","url":"https:\/\/mindthegraph.com\/blog\/success-case-igh-resolution-synchrotron-based-x-ray-microtomography-as-a-tool-to-unveil-the-three-dimensional-neuronal-architecture-of-the-brain\/","name":"High-resolution synchrotron-based X-ray microtomography as a tool to unveil the three-dimensional neuronal architecture of the brain Paper Review - Mind the Graph Blog","isPartOf":{"@id":"https:\/\/mindthegraph.com\/blog\/#website"},"datePublished":"2022-09-08T21:14:00+00:00","dateModified":"2023-03-17T17:47:54+00:00","author":{"@id":"https:\/\/mindthegraph.com\/blog\/#\/schema\/person\/b44995c1d77b52a63b6d11262b740b02"},"description":"Look into the new method for deciphering the cytoarchitecture and connectivity of the brain represented with Mind the Graph's illustrations.","breadcrumb":{"@id":"https:\/\/mindthegraph.com\/blog\/success-case-igh-resolution-synchrotron-based-x-ray-microtomography-as-a-tool-to-unveil-the-three-dimensional-neuronal-architecture-of-the-brain\/#breadcrumb"},"inLanguage":"lt-LT","potentialAction":[{"@type":"ReadAction","target":["https:\/\/mindthegraph.com\/blog\/success-case-igh-resolution-synchrotron-based-x-ray-microtomography-as-a-tool-to-unveil-the-three-dimensional-neuronal-architecture-of-the-brain\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/mindthegraph.com\/blog\/success-case-igh-resolution-synchrotron-based-x-ray-microtomography-as-a-tool-to-unveil-the-three-dimensional-neuronal-architecture-of-the-brain\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/mindthegraph.com\/blog\/"},{"@type":"ListItem","position":2,"name":"High-resolution synchrotron-based X-ray microtomography as a tool to unveil the three-dimensional neuronal architecture of the brain Paper Review"}]},{"@type":"WebSite","@id":"https:\/\/mindthegraph.com\/blog\/#website","url":"https:\/\/mindthegraph.com\/blog\/","name":"Mind the Graph Blog","description":"Your science can be beautiful!","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/mindthegraph.com\/blog\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"lt-LT"},{"@type":"Person","@id":"https:\/\/mindthegraph.com\/blog\/#\/schema\/person\/b44995c1d77b52a63b6d11262b740b02","name":"Artur Zignani","image":{"@type":"ImageObject","inLanguage":"lt-LT","@id":"https:\/\/mindthegraph.com\/blog\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/a211ec97011fe24f7a8e63a7ca799342?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/a211ec97011fe24f7a8e63a7ca799342?s=96&d=mm&r=g","caption":"Artur Zignani"},"url":"https:\/\/mindthegraph.com\/blog\/lt\/author\/artur\/"}]}},"_links":{"self":[{"href":"https:\/\/mindthegraph.com\/blog\/lt\/wp-json\/wp\/v2\/posts\/16630"}],"collection":[{"href":"https:\/\/mindthegraph.com\/blog\/lt\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mindthegraph.com\/blog\/lt\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/lt\/wp-json\/wp\/v2\/users\/29"}],"replies":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/lt\/wp-json\/wp\/v2\/comments?post=16630"}],"version-history":[{"count":5,"href":"https:\/\/mindthegraph.com\/blog\/lt\/wp-json\/wp\/v2\/posts\/16630\/revisions"}],"predecessor-version":[{"id":27198,"href":"https:\/\/mindthegraph.com\/blog\/lt\/wp-json\/wp\/v2\/posts\/16630\/revisions\/27198"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/lt\/wp-json\/wp\/v2\/media\/20013"}],"wp:attachment":[{"href":"https:\/\/mindthegraph.com\/blog\/lt\/wp-json\/wp\/v2\/media?parent=16630"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/lt\/wp-json\/wp\/v2\/categories?post=16630"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mindthegraph.com\/blog\/lt\/wp-json\/wp\/v2\/tags?post=16630"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}