{"id":10972,"date":"2020-03-20T08:22:00","date_gmt":"2020-03-20T11:22:00","guid":{"rendered":"https:\/\/blog.mindthegraph.com\/?p=10972"},"modified":"2022-10-18T08:09:52","modified_gmt":"2022-10-18T11:09:52","slug":"coronavirus-covid-19-is-hydroxychloroquine-the-new-hope-apparently-yes","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/lt\/coronavirus-covid-19-is-hidroksichlorokvinas-naujoji-viltis-apie-tiketinai-teisinga\/","title":{"rendered":"Koronavirusas (Covid-19): ar hidroksichlorochinas yra nauja viltis? Matyt, taip."},"content":{"rendered":"

Dvi naujausi dokumentai apibendrino vien\u0105 in vitro tyrim\u0105 ir nedidel\u0117s apimties klinikin\u012f tyrim\u0105, kurio pakako, kad Donaldas Trumpas priverst\u0173 FDA taikyti nauj\u0105 vaisto klinikin\u0119 indikacij\u0105 hidroksichlorochinui: pagerinti koronaviruso (Covid-19) paveikt\u0173 pacient\u0173 simptomus.<\/p>\n

Tai tikriausiai grei\u010diausias vaist\u0173 patvirtinimo procesas \u0161iuolaikin\u0117je istorijoje, ir prezidentas, matyt, yra teisus. Keista pasaulio lyderiui, kuris nelabai m\u0117gsta moksl\u0105.<\/p>\n

\"\"<\/p>\n

Pirmieji \u012frodymai apie hidroksichlorochino poveik\u012f virusui gauti i\u0161 \u0161is dokumentas paskelbtas vakar \"Cell Discovery<\/a>Tai tik in vitro tyrimas su visais apribojimais, ta\u010diau jis ai\u0161kiai rodo, kad vaistas gali sunaikinti virus\u0105. Kai jie pateik\u0117 dokument\u0105, Kinijoje buvo patvirtinta 80 000 atvej\u0173, \u012fskaitant 2946 mirties atvejus, taip pat daugiau kaip 10 566 patvirtinti atvejai 72 kitose \u0161alyse. Tuo metu did\u017eiausios viltys buvo dedamos \u012f vaist\u0105, vadinam\u0105 remdesiviru.<\/p>\n

\"hidrochlorochino
Hidrochlorochino poveikis koronavirusui (Covid-19) in vitro. De\u0161in\u0117je esan\u010diame stulpelyje parodytas veiksmingo vaisto poveikis, palyginti su chlorochinu arba kontroline grupe kair\u0117je. Tai rodo, kad vaistas pagerino l\u0105steli\u0173 geb\u0117jim\u0105 i\u0161stumti virusus... Tai tarsi pagalba i\u0161varyti nepageidaujam\u0105 kaimyn\u0105 i\u0161 nam\u0173. Tai padeda! \ud83d\ude42 <\/figcaption><\/figure>\n

Ta\u010diau did\u017eiausia naujiena - dien\u0105 prie\u0161 tai paskelbtas nedidel\u0117s apimties klinikinis tyrimas. Pavadinimas Hidroksichlorochinas ir azitromicinas kaip COVID-19 gydymo b\u016bdas: atviro nerandomizuoto klinikinio tyrimo rezultatai, kuriuos galima atsisi\u0173sti i\u0161 \"in press\" versijos<\/a><\/p>\n

Atlik\u0119 tyrim\u0105, kuriame dalyvavo tik 20 pacient\u0173, autoriai \u012frod\u0117, kad hidroksichlorokvinas buvo veiksmingas nuo koronaviruso Covid-19 infekcijos. I\u0161 tikr\u0173j\u0173 jis per 6 dienas suma\u017eino 75% u\u017esikr\u0117tusi\u0173 asmen\u0173, o tai yra nuostabu. Dar geriau, kad derinys su azitromicinu pagerino gydymo veiksmingum\u0105 iki 95%.<\/p>\n

\"Hidrolichrochino
Hidrolichrochino ir azitromicino derinys yra veiksmingas prie\u0161 koronaviruso (Covid-19) infekcijas \u017emon\u0117ms. \u0160is suma\u017e\u0117jimas yra dramati\u0161kas ir suteikia nauj\u0105 vilt\u012f sergantiems pacientams.<\/figcaption><\/figure>\n

Gydymas pagerino ligos simptomus ir suma\u017eino viruso kiek\u012f. Vaistas anks\u010diau buvo patvirtintas maliarijai gydyti, o tai rei\u0161kia, kad jis laikomas saugiu. \"Giminingas\" vaistas chlorochinas buvo ma\u017eiau veiksmingas. Mums gerai, nes jis algo toksi\u0161kesnis.<\/p>\n

Tyrimas nebuvo atsitiktin\u0117s atrankos b\u016bdu atliktas ir yra nedidel\u0117s apimties, ta\u010diau atrodo, kad nors epidemija prasid\u0117jo Kinijoje, sprendim\u0105 galima rasti pasaulin\u0117s bendruomen\u0117s pastangomis. I\u0161 tikr\u0173j\u0173 in vitro dokumentas yra kin\u0173, o klinikinis - europie\u010di\u0173, tiksliau, pranc\u016bz\u0173. \u012edomu tai, kad pirmin\u0117 vaisto hidroksichlorochino registracija yra Pranc\u016bzijos farmacijos bendrov\u0117s \"Sanofi\", o neseniai atliktas klinikinis tyrimas buvo atliktas Marselyje. Ale le bleu!<\/p>\n

\"Medscape\" pateikia puik\u0173 straipsn\u012f apie tai, jei norite gauti i\u0161samesn\u0117s informacijos.<\/a><\/p>\n

Pra\u0161ome cituoti \u0161\u012f darb\u0105 kaip Gautret et al. (2020) Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial. International Journal of Antimicrobial Agents - In Press 2020 m. kovo 17 d. - DOI : 10.1016\/j.ijantimicag.2020.105949<\/p>","protected":false},"excerpt":{"rendered":"","protected":false},"author":4,"featured_media":11134,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[419,959,28],"tags":[400,394,396,388,389,398,397,399,92,53,554,395,250,393],"yoast_head":"\nCoronavirus Covid-19: hydroxychloroquine, the new hope?<\/title>\n<meta name=\"description\" content=\"Hydroxycholoquine is the new hope for coronavirus (Covid-19) infection. 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