{"id":19837,"date":"2022-09-15T11:59:00","date_gmt":"2022-09-15T14:59:00","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=19837"},"modified":"2023-03-20T09:54:50","modified_gmt":"2023-03-20T12:54:50","slug":"cutaneous-and-acral-melanoma","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/ja\/%e7%9a%ae%e8%86%9a%e3%83%bb%e8%85%8b%e7%aa%a9%e3%83%a1%e3%83%a9%e3%83%8e%e3%83%bc%e3%83%9e\/","title":{"rendered":"\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u76ae\u819a\u9ed2\u8272\u816b\u3068\u984e\u9aa8\u9ed2\u8272\u816b"},"content":{"rendered":"<p>\u6570\u5341\u5e74\u524d\u304b\u3089\u3001\u4e00\u90e8\u306e\u96c6\u56e3\u3067\u306f\u4e16\u754c\u7684\u306b\u30e1\u30e9\u30ce\u30fc\u30de\u306e\u767a\u751f\u7387\u304c\u5897\u52a0\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u76ae\u819a\u3001\u7c98\u819c\u3001\u307e\u305f\u306f\u3076\u3069\u3046\u819c\u306e\u30e1\u30e9\u30ce\u30b5\u30a4\u30c8\u306e\u65b0\u751f\u7269\u306f\u3001\u30e1\u30e9\u30ce\u30fc\u30de\u3068\u3057\u3066\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3059\u3079\u3066\u306e\u76ae\u819a\u60aa\u6027\u816b\u760d\u306e\u4e2d\u30675%\u3092\u5360\u3081\u308b\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u3001\u76ae\u819a\u304c\u3093\u306b\u3088\u308b\u6b7b\u4ea1\u306e75%\u4ee5\u4e0a\u306e\u539f\u56e0\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u00a0<\/p>\n\n\n\n<p>\u7d2b\u5916\u7dda\u66dd\u9732\u3068\u30e1\u30e9\u30ce\u30fc\u30de\u767a\u75c7\u3068\u306e\u6b63\u306e\u95a2\u9023\u306f\u3088\u304f\u77e5\u3089\u308c\u3066\u3044\u308b\u304c\u3001\u30d2\u30c8\u306e\u30e1\u30e9\u30ce\u30fc\u30de\u7d44\u7e54\u3067\u306f\u305d\u306e\u80cc\u666f\u306b\u3042\u308b\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30c3\u30af\u306a\u30e1\u30ab\u30cb\u30ba\u30e0\u306f\u307b\u3068\u3093\u3069\u672a\u89e3\u660e\u3067\u3042\u308b\u3002\u672c\u7a3f\u3067\u306f\u3001\u75c5\u7406\u751f\u7269\u5b66\u3068\u7d2b\u5916\u7dda\u66dd\u9732\u306b\u95a2\u9023\u3059\u308b\u4e88\u5f8c\u4e0d\u826f\u306e\u764c\u30c9\u30e9\u30a4\u30d0\u30fc\u306b\u3064\u3044\u3066\u3001\u524d\u8ff0\u306e\u30c8\u30d4\u30c3\u30af\u306b\u95a2\u3059\u308b\u7b46\u8005\u306e\u8003\u5bdf\u3092\u4ea4\u3048\u3066\u7d39\u4ecb\u3059\u308b\u3002&nbsp;<\/p>\n\n\n\n<h2>\u7814\u7a76\u306e\u306d\u3089\u3044<\/h2>\n\n\n\n<p>\u76ae\u819a\u30e1\u30e9\u30ce\u30fc\u30de\u60a3\u8005\u306e2\u3064\u306e\u72ec\u7acb\u3057\u305f\u30b3\u30db\u30fc\u30c8\u3092\u7528\u3044\u3066\u3001\u7d2b\u5916\u7dda\u5909\u7570\u306b\u95a2\u9023\u3059\u308b\u30b2\u30ce\u30e0\u5168\u4f53\u306e\u30e1\u30c1\u30eb\u5316\u5909\u5316\u3092\u767a\u898b\u3057\u3001\u691c\u8a3c\u3059\u308b\u3053\u3068\u3092\u76ee\u7684\u3068\u3057\u3066\u3044\u308b\u3002\u4e3b\u306a\u76ee\u7684\u306f\u3001\u7d2b\u5916\u7dda\u5909\u7570\u578b\u76ae\u819a\u9ed2\u8272\u816b\u3068\u975e\u7d2b\u5916\u7dda\u5909\u7570\u578b\u76ae\u819a\u9ed2\u8272\u816b\u3092\u533a\u5225\u3059\u308b\u305f\u3081\u306eDNA\u30e1\u30c1\u30eb\u5316\u5bfe\u30c8\u30e9\u30f3\u30b9\u30af\u30ea\u30d7\u30c8\u30fc\u30e0\u304a\u3088\u3073\u7d71\u5408\u30e1\u30c1\u30eb\u5316\u5bfe\u30c8\u30e9\u30f3\u30b9\u30af\u30ea\u30d7\u30c8\u30fc\u30e0\u306e\u8a3a\u65ad\u80fd\u3092\u8abf\u67fb\u3059\u308b\u3053\u3068\u3067\u3042\u308b\u3002&nbsp;<\/p>\n\n\n\n<p>\u7d71\u5408\u7684\u306aOMIC\u30a2\u30d7\u30ed\u30fc\u30c1\u3092\u7528\u3044\u3066\u3001\u512a\u5148\u7684\u306b\u30e1\u30c1\u30eb\u5316\u3055\u308c\u305f\u5dee\u7570\u907a\u4f1d\u5b50\u306e\u5c0f\u5869\u57fa\u5909\u7570\uff08SNVs\uff09\u3068\u30b3\u30d4\u30fc\u6570\u5909\u7570\uff08CNVs\uff09\u3092\u3001\u304c\u3093\u30c9\u30e9\u30a4\u30d0\u30fc\u306e\u53ef\u80fd\u6027\u306b\u3064\u3044\u3066\u8a55\u4fa1\u3059\u308b\u3002\u3053\u306e\u7814\u7a76\u306f\u3055\u3089\u306b\u3001DNA\u30e1\u30c1\u30ed\u30fc\u30e0\u304c\u3001\u7d2b\u5916\u7dda\u3078\u306e\u66dd\u9732\u306b\u95a2\u9023\u3059\u308b\u8457\u540d\u306a\u30e1\u30e9\u30ce\u30fc\u30de\u306e\u5909\u7570\u4f53\uff08\u76ae\u819a\u30e1\u30e9\u30ce\u30fc\u30de\uff09\u3068\u305d\u3046\u3067\u306a\u3044\u3082\u306e\uff08\u7121\u5c3e\u90e8\u30e1\u30e9\u30ce\u30fc\u30de\uff09\u306e\u75c5\u7406\u5b66\u7684\u304a\u3088\u3073\u7d2b\u5916\u7dda\u95a2\u9023\u306e\u9055\u3044\u3092\u533a\u5225\u3067\u304d\u308b\u304b\u3069\u3046\u304b\u3092\u691c\u8a0e\u3059\u308b\u5225\u306e\u7814\u7a76\u306b\u3088\u3063\u3066\u88cf\u4ed8\u3051\u3089\u308c\u3066\u3044\u308b\u3002\u8ad6\u6587\u4e2d\u306e\u56f3\u306f\u3001\u3053\u306e\u7814\u7a76\u306e\u76ee\u6a19\u3068\u30d7\u30ed\u30bb\u30b9\u304c\u4f55\u3067\u3042\u308b\u304b\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u56f3\u89e3\u306f\u3001\u4ee5\u4e0b\u3092\u4f7f\u7528\u3057\u3066\u4f5c\u6210\u3055\u308c\u307e\u3057\u305f\u3002 <strong><a href=\"https:\/\/mindthegraph.com\">Mind the Graph<\/a><\/strong>.<\/p>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><a href=\"https:\/\/mindthegraph.com\/app\/offer-trial\"><img decoding=\"async\" loading=\"lazy\" width=\"651\" height=\"174\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2023\/02\/banner-blog-trial-01.jpg\" alt=\"\" class=\"wp-image-26823\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2023\/02\/banner-blog-trial-01.jpg 651w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2023\/02\/banner-blog-trial-01-300x80.jpg 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2023\/02\/banner-blog-trial-01-18x5.jpg 18w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2023\/02\/banner-blog-trial-01-100x27.jpg 100w\" sizes=\"(max-width: 651px) 100vw, 651px\" \/><\/a><\/figure><\/div>\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2>\u7814\u7a76\u3092\u8a73\u7d30\u306b\u691c\u8a0e\u3059\u308b<\/h2>\n\n\n\n<p>\u81e8\u5e8a\u751f\u7269\u8a66\u6599\u306b\u304a\u3044\u3066\u3001\u7d2b\u5916\u7dda\uff08UV\uff09\u306f\u76ae\u819a\u9ed2\u8272\u816b\u3068\u306e\u95a2\u9023\u304c\u6307\u6458\u3055\u308c\u3066\u3044\u308b\u304c\u3001\u305d\u306e\u80cc\u666f\u306b\u3042\u308b\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30c3\u30af\u306a\u30e1\u30ab\u30cb\u30ba\u30e0\u306f\u307e\u3060\u89e3\u660e\u3055\u308c\u3066\u3044\u306a\u3044\u3002\u672c\u7814\u7a76\u3067\u306f\u3001112\u306e\u76ae\u819a\u30e1\u30e9\u30ce\u30fc\u30de\u7d30\u80de\u3092\u542b\u3080\u591a\u6c11\u65cf\u30b3\u30db\u30fc\u30c8\u3092\u5bfe\u8c61\u306b\u3001\u81e8\u5e8a\u3001\u30a8\u30d4\u30b2\u30ce\u30e0\uff08DNA\u30e1\u30c1\u30ed\u30fc\u30e0\uff09\u3001\u30b2\u30ce\u30e0\u3001\u30c8\u30e9\u30f3\u30b9\u30af\u30ea\u30d7\u30c8\u30fc\u30e0\u306e\u30d7\u30ed\u30d5\u30a1\u30a4\u30ea\u30f3\u30b0\u3092\u884c\u3063\u305f\u3002\u672c\u7814\u7a76\u3067\u306f\u3001\u591a\u6c11\u65cf\u306e\u9593\u3067\u304c\u3093\u30c9\u30e9\u30a4\u30d0\u30fc\u3068\u306a\u308a\u3046\u308b\u514d\u75ab\u30fb\u5236\u5fa1\u7d4c\u8def\u306b\u304a\u3051\u308b\u7d2b\u5916\u7dda\u306b\u3088\u308b\u5909\u5316\u3092\u540c\u5b9a\u3057\u3066\u3044\u308b\u3002<\/p>\n\n\n\n<p>TAPBP\uff08Tap binding protein gene\uff09\u306f\u3001\u514d\u75ab\u6a5f\u80fd\u306b\u6c7a\u5b9a\u7684\u306b\u95a2\u4e0e\u3059\u308b\u907a\u4f1d\u5b50\u3067\u3042\u308b\u3053\u3068\u306b\u52a0\u3048\u3001\u6a19\u7684\u914d\u5217\u6c7a\u5b9a\u306b\u3088\u308a\u691c\u8a3c\u3055\u308c\u305f\u3044\u304f\u3064\u304b\u306e\u7d2b\u5916\u7dda\u306b\u3088\u308b\u30e1\u30c1\u30eb\u5316\u90e8\u4f4d\u304c\u3001\u81e8\u5e8a\u5fdc\u7528\u306e\u6a5f\u4f1a\u3092\u63d0\u4f9b\u3057\u3066\u3044\u307e\u3059\u3002MHC-I\u306f\u3001\u514d\u75ab\u30b0\u30ed\u30d6\u30ea\u30f3\u30b9\u30fc\u30d1\u30fc\u30d5\u30a1\u30df\u30ea\u30fc\u306e\u30e1\u30f3\u30d0\u30fc\u3067\u3042\u308bTAPBP\u3092\u4ecb\u3057\u3066\u3001\u6297\u539f\u30d7\u30ed\u30bb\u30c3\u30b7\u30f3\u30b0\u306b\u95a2\u9023\u3059\u308b\u30c8\u30e9\u30f3\u30b9\u30dd\u30fc\u30bf\u30fc\u3068\u76f8\u4e92\u4f5c\u7528\u3057\u3066\u3044\u308b\u3002\u591a\u304f\u306e\u764c\u3067TAPBP\uff08\u30bf\u30d1\u30b7\u30f3\uff09\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u30c0\u30a6\u30f3\u30ec\u30ae\u30e5\u30ec\u30fc\u30b7\u30e7\u30f3\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u308b\u304c\u3001\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u66b4\u9732\u5f8c\u306b\u56de\u5fa9\u3057\u3066\u3044\u308b\u3002\u00a0<\/p>\n\n\n\n<p>\u3053\u306e\u3053\u3068\u304b\u3089\u3001TAPBP\u306e\u767a\u73fe\u4e0d\u5168\u306f\u3001\u69cb\u9020\u7684\u306a\u5909\u5316\u3068\u3044\u3046\u3088\u308a\u3082\u3001\u3080\u3057\u308d\u8abf\u7bc0\u969c\u5bb3\u306b\u3088\u3063\u3066\u5f15\u304d\u8d77\u3053\u3055\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u305f\u3002\u7814\u7a76\u30c1\u30fc\u30e0\u306f\u3001TAPBP\u306eDNA\u30e1\u30c1\u30eb\u5316\u30ec\u30d9\u30eb\u306f\u8ee2\u5199\u3068\u6709\u610f\u306b\u9006\u76f8\u95a2\u3057\u3066\u304a\u308a\u3001\u5f8c\u8005\u306f\u30e1\u30e9\u30ce\u30fc\u30de\u306e\u75c5\u7406\u5b66\u7684\u30a2\u30a4\u30c7\u30f3\u30c6\u30a3\u30c6\u30a3\u3088\u308a\u3082\u3080\u3057\u308d\u7d2b\u5916\u7dda\u66dd\u9732\u306e\u7d50\u679c\u3068\u3057\u3066\u5909\u5316\u3059\u308b\u3053\u3068\u3092\u898b\u51fa\u3057\u305f\u3002UV\u5909\u7570\u306e\u306a\u3044\u76ae\u819a\u30e1\u30e9\u30ce\u30fc\u30de\u3068\u7121\u82b1\u679c\u30e1\u30e9\u30ce\u30fc\u30de\u306e\u3044\u305a\u308c\u3082\u3001\u30e1\u30c1\u30eb\u5316\u306b\u5dee\u306f\u8a8d\u3081\u3089\u308c\u306a\u304b\u3063\u305f\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001TAPBP\u3092\u4e2d\u5fc3\u3068\u3057\u305f\u77e5\u898b\u3068\u306f\u5225\u306b\u3001\u7d2b\u5916\u7dda\u5909\u7570\u306f\u76ae\u819a\u30e1\u30e9\u30ce\u30fc\u30de\u306e\u30e1\u30c1\u30ed\u30fc\u30e0\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u69d8\u3005\u306a\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30c3\u30af\u306a\u5909\u5316\u3068\u95a2\u9023\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u660e\u3089\u304b\u306b\u3057\u305f\u3002\u3053\u306e\u7d50\u679c\u306f\u3001\u76ae\u819a\u30e1\u30e9\u30ce\u30fc\u30de\u306f\u3001UV\u5909\u7570\u578b\u3067\u3042\u308d\u3046\u3068\u975eUV\u5909\u7570\u578b\u3067\u3042\u308d\u3046\u3068\u3001\u540c\u3058\u75c5\u614b\u30fb\u7d30\u80de\u7531\u6765\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u3066\u3082\u3001\u5225\u3005\u306b\u5206\u985e\u3055\u308c\u308b\u5fc5\u8981\u304c\u3042\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u308b\u3002\u3053\u308c\u306f\u3001\u305d\u308c\u3089\u304c\u7531\u6765\u3059\u308b\u30a8\u30d4\u30b2\u30ce\u30e0\u30e9\u30f3\u30c9\u30b9\u30b1\u30fc\u30d7\u304c\u3001\u88ab\u3070\u304f\u3068\u7d30\u80de\u7cfb\u306e\u4e21\u65b9\u306e\u30de\u30fc\u30ab\u30fc\u3092\u542b\u3080\u53ef\u80fd\u6027\u304c\u3042\u308b\u305f\u3081\u3067\u3042\u308b\u3002&nbsp;<\/p>\n\n\n\n<p>\u672c\u7814\u7a76\u3067\u306f\u3001WGS\u3001WES\u3001RNA\u30b7\u30fc\u30b1\u30f3\u30b9\u3001DNA\u30e1\u30c1\u30ed\u30fc\u30e0\u30ef\u30a4\u30c9\u30d7\u30ed\u30d5\u30a1\u30a4\u30ea\u30f3\u30b0\u306a\u3069\u306e\u8907\u6570\u306e\u5f37\u529b\u306a\u6280\u8853\u304c\u3001\u6700\u5148\u7aef\u306e\u30d0\u30a4\u30aa\u30a4\u30f3\u30d5\u30a9\u30de\u30c6\u30a3\u30af\u30b9\u30c4\u30fc\u30eb\u3068\u3068\u3082\u306b\u3001\u76ae\u819a\u304a\u3088\u3073\u5148\u5929\u6027\u9ed2\u8272\u816b\u30b5\u30f3\u30d7\u30eb\u306b\u9069\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u7814\u7a76\u8005\u3089\u306f\u3001\u4e00\u822c\u306b\u516c\u958b\u3055\u308c\u3066\u3044\u308b\u30c7\u30fc\u30bf\u3092\u4f7f\u7528\u3057\u3001\u3088\u308a\u5927\u304d\u306a\u30b5\u30f3\u30d7\u30eb\u30b5\u30a4\u30ba\u3001\u3088\u308a\u5e83\u3044\u30b2\u30ce\u30e0\u30ab\u30d0\u30ec\u30c3\u30b8\u3001\u5305\u62ec\u7684\u306a\u8868\u73fe\u578b\u8a55\u4fa1\u3001\u4fdd\u5b58\u72b6\u614b\u306e\u826f\u3044\u51b7\u51cd\u7d44\u7e54\u30b5\u30f3\u30d7\u30eb\u3001\u76ae\u819a\u4ee5\u5916\u306e\u30e1\u30e9\u30ce\u30fc\u30de\u3084\u30e8\u30fc\u30ed\u30c3\u30d1\u4eba\u4ee5\u5916\u306e\u6c11\u65cf\u306e\u8a55\u4fa1\u306a\u3069\u3001\u65b0\u3057\u3044\u30c7\u30fc\u30bf\u30bb\u30c3\u30c8\u3067\u88dc\u5b8c\u3057\u305f\u3002&nbsp;<\/p>\n\n\n\n<h2>\u3053\u306e\u4f5c\u696d\u306e\u7d50\u679c\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u6210\u679c\u304c\u5f97\u3089\u308c\u307e\u3057\u305f\u3002<\/h2>\n\n\n\n<p>(1) \u304c\u3093\u30ea\u30b9\u30af\u306e\u5c64\u5225\u5316\u306b\u5229\u7528\u3067\u304d\u308b\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u306e\u767a\u898b\u3002<\/p>\n\n\n\n<p>(2) \u30e1\u30e9\u30ce\u30fc\u30de\u306e\u30bf\u30a4\u30d7\u5185\u304a\u3088\u3073\u30bf\u30a4\u30d7\u9593\u306e\u5206\u985e\u306e\u6539\u5584\u3002&nbsp;<\/p>\n\n\n\n<p>(3) \u6cbb\u7642\u306e\u30bf\u30fc\u30b2\u30c3\u30c8\u3068\u306a\u308a\u3046\u308b\u30e1\u30e9\u30ce\u30fc\u30de\u5f62\u6210\u306e\u5206\u5b50\u30c9\u30e9\u30a4\u30d0\u30fc\u3092\u7279\u5b9a\u3059\u308b\u3002&nbsp;<\/p>\n\n\n\n<p>(4)\u30e1\u30e9\u30ce\u30fc\u30de\u306e\u75c5\u614b\u306b\u95a2\u3059\u308b\u77e5\u8b58\u3092\u6df1\u3081\u3001\u4eba\u53e3\u683c\u5dee\u306e\u662f\u6b63\u3092\u56f3\u308b\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u7814\u7a76\u306f\u3001\u4ed6\u306e\u30bf\u30a4\u30d7\u306e\u30e1\u30e9\u30ce\u30fc\u30de\u306b\u304a\u3051\u308b\u540c\u69d8\u306e\u907a\u4f1d\u5b50\u74b0\u5883\u7814\u7a76\u306e\u30ed\u30fc\u30c9\u30de\u30c3\u30d7\u3092\u63d0\u4f9b\u3059\u308b\u3082\u306e\u3067\u3042\u308a\u3001\u4e00\u822c\u7684\u306a\u30e1\u30e9\u30ce\u30fc\u30de\u3068\u983b\u5ea6\u306e\u4f4e\u3044\u30e1\u30e9\u30ce\u30fc\u30de\u306e\u4e21\u65b9\u3092\u5bfe\u8c61\u306b\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h2>\u6b63\u78ba\u306a\u79d1\u5b66\u60c5\u5831\u3092\u4f1d\u3048\u308b\u3088\u308a\u52b9\u679c\u7684\u306a\u65b9\u6cd5<\/h2>\n\n\n\n<p>\u3053\u306e\u7814\u7a76\u8ad6\u6587\u306f\u3001\u4e3b\u306b\u7f8e\u3057\u3044\u30b0\u30e9\u30d5\u30a3\u30ab\u30eb\u306a\u30a4\u30e9\u30b9\u30c8\u306b\u3088\u3063\u3066\u3001\u975e\u5e38\u306b\u8208\u5473\u6df1\u304f\u3001\u7406\u89e3\u3057\u3084\u3059\u3044\u3082\u306e\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u30b0\u30e9\u30d5\u306e\u4f5c\u6210\u306b\u306f <a href=\"https:\/\/mindthegraph.com\">Mind the Graph<\/a> \u30c4\u30fc\u30eb\u306b\u306a\u308a\u307e\u3059\u3002\u56f3\u89e3\u306f\u69d8\u3005\u306a\u5f62\u3067\u8aad\u8005\u306b\u5229\u76ca\u3092\u3082\u305f\u3089\u3059\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002Mind the Graph\u306b\u7121\u6599\u3067\u767b\u9332\u3057\u3001\u6700\u521d\u306e\u79d1\u5b66\u56f3\u9451\u306b\u6311\u6226\u3057\u3066\u3001\u7814\u7a76\u306e\u30ec\u30d9\u30eb\u30a2\u30c3\u30d7\u3092\u56f3\u3063\u3066\u307f\u3066\u306f\u3044\u304b\u304c\u3067\u3057\u3087\u3046\u304b\u3002<br><br>\u79c1\u305f\u3061\u306e\u8a18\u4e8b \" \u3092\u30c1\u30a7\u30c3\u30af\u3059\u308b\u3053\u3068\u3092\u5fd8\u308c\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002<a href=\"https:\/\/mindthegraph.com\/blog\/the-key-visual-science-scientific-illustration\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u30b5\u30a4\u30a8\u30f3\u30c6\u30a3\u30d5\u30a3\u30c3\u30af\u30a4\u30e9\u30b9\u30c8\u30ec\u30fc\u30b7\u30e7\u30f3\u8996\u899a\u79d1\u5b66\u306e\u4e16\u754c\u3078\u306e\u9375<\/a>&#8220;. <\/p>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" loading=\"lazy\" width=\"594\" height=\"463\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/11\/scientifically-accurate-posters.png\" alt=\"\" class=\"wp-image-25484\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/11\/scientifically-accurate-posters.png 594w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/11\/scientifically-accurate-posters-300x234.png 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/11\/scientifically-accurate-posters-15x12.png 15w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/11\/scientifically-accurate-posters-100x78.png 100w\" sizes=\"(max-width: 594px) 100vw, 594px\" \/><\/figure><\/div>\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"is-content-justification-center is-layout-flex wp-container-1 wp-block-buttons\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-background wp-element-button\" href=\"https:\/\/mindthegraph.com\/science_figures\" style=\"border-radius:50px;background-color:#dc1866\" target=\"_blank\" rel=\"noreferrer noopener\">\u52b9\u679c\u7684\u306a\u7406\u79d1\u306e\u56f3\u5f62\u3092\u6570\u5206\u3067\u4f5c\u6210<\/a><\/div>\n<\/div>\n\n\n\n<div style=\"height:25px\" aria-hidden=\"true\" 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content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mindthegraph.com\/blog\/ja\/\u76ae\u819a\u30fb\u814b\u7aa9\u30e1\u30e9\u30ce\u30fc\u30de\/\" \/>\n<meta property=\"og:locale\" content=\"ja_JP\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Paper Review: Cutaneous and Acral Melanoma\" \/>\n<meta property=\"og:description\" content=\"This article will discuss the prognostic cancer driver related to pathobiology and ultraviolet exposure along with the author&#039;s insights.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/mindthegraph.com\/blog\/ja\/\u76ae\u819a\u30fb\u814b\u7aa9\u30e1\u30e9\u30ce\u30fc\u30de\/\" \/>\n<meta property=\"og:site_name\" content=\"Mind the Graph Blog\" \/>\n<meta property=\"article:published_time\" content=\"2022-09-15T14:59:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-03-20T12:54:50+00:00\" 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