{"id":16630,"date":"2022-09-08T18:14:00","date_gmt":"2022-09-08T21:14:00","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/success-case-zika-virus-replicates-in-adult-human-brain-tissue-and-impairs-synapses-and-memory-in-mice-copy\/"},"modified":"2023-03-17T14:47:54","modified_gmt":"2023-03-17T17:47:54","slug":"success-case-igh-resolution-synchrotron-based-x-ray-microtomography-as-a-tool-to-unveil-the-three-dimensional-neuronal-architecture-of-the-brain","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/ja\/%e6%88%90%e5%8a%9f%e4%be%8b-%e9%ab%98%e8%a7%a3%e5%83%8f%e5%ba%a6%e3%82%b7%e3%83%b3%e3%82%af%e3%83%ad%e3%83%88%e3%83%ad%e3%83%b3x%e7%b7%9a%e3%83%9e%e3%82%a4%e3%82%af%e3%83%ad%e3%83%88%e3%83%a2%e3%82%b0\/","title":{"rendered":"\u9ad8\u5206\u89e3\u80fd\u653e\u5c04\u5149X\u7dda\u30de\u30a4\u30af\u30ed\u30c8\u30e2\u30b0\u30e9\u30d5\u30a3\u30fc\u306b\u3088\u308b\u8133\u306e3\u6b21\u5143\u795e\u7d4c\u7d30\u80de\u69cb\u9020\u306e\u89e3\u660e 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Fonseca\u3089\uff082018\uff09\u306f\u3001\u300c\u8133\u306e3\u6b21\u5143\u795e\u7d4c\u7d30\u80de\u69cb\u9020\u3092\u660e\u3089\u304b\u306b\u3059\u308b\u30c4\u30fc\u30eb\u3068\u3057\u3066\u306e\u9ad8\u89e3\u50cf\u5ea6\u30b7\u30f3\u30af\u30ed\u30c8\u30ed\u30f3\u30d9\u30fc\u30b9X\u7dda\u30de\u30a4\u30af\u30ed\u30c8\u30e2\u30b0\u30e9\u30d5\u30a3\u30fc\u300d\u306b\u304a\u3044\u3066\u3001\u795e\u7d4c\u7d30\u80de\u3092\u500b\u5225\u5316\u3057\u305f\u5358\u4e00\u4f53\u3068\u3057\u3066\u7814\u7a76\u3059\u308b\u3053\u3068\u306f\u300119\u4e16\u7d00\u306b\u300c\u30cb\u30e5\u30fc\u30ed\u30f3\u5b66\u8aac\u300d\u304c\u4f5c\u3089\u308c\u305f\u3053\u3068\u306b\u7aef\u3092\u767a\u3057\u3066\u3044\u308b\u3068\u8ff0\u3079\u3066\u3044\u307e\u3059\u3002 <\/p>\n\n\n\n<p>\u3053\u3053\u6570\u5e74\u3001\u7121\u50b7\u306e\u8133\u30b5\u30f3\u30d7\u30eb\u306b\u304a\u3051\u308b\u795e\u7d4c\u7d30\u80de\u306e\u7d44\u7e54\u3068\u7d50\u5408\u3092\u7406\u89e3\u3059\u308b\u305f\u3081\u306b\u3001\u5927\u304d\u306a\u52aa\u529b\u304c\u6255\u308f\u308c\u3066\u3044\u308b\u3002\u30b4\u30eb\u30b8-\u30b3\u30c3\u30af\u30b9\u30e9\u30d9\u30ea\u30f3\u30b0\u6cd5\u306f\u3001X\u7dda\u30de\u30a4\u30af\u30ed\u30c8\u30e2\u30b0\u30e9\u30d5\u30a3\u30fc\u3067\u795e\u7d4c\u7d30\u80de\u3092\u7279\u7570\u7684\u306b\u30e9\u30d9\u30ea\u30f3\u30b0\u3059\u308b\u306e\u306b\u9069\u3057\u305f\u30b3\u30f3\u30c8\u30e9\u30b9\u30c8\u3092\u63d0\u4f9b\u3059\u308b\u6280\u8853\u3067\u3059\u3002 <\/p>\n\n\n\n<p>\u795e\u7d4c\u7d30\u80de\u306f\u3001\u305d\u306e\u6b63\u5e38\u306a\u6a5f\u80fd\u306b\u4e0d\u53ef\u6b20\u306a\u3001\u660e\u78ba\u306a\u5f62\u614b\u3068\u7279\u7570\u306a\u7d50\u5408\u30d1\u30bf\u30fc\u30f3\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002\u7814\u7a76\u8005\u3089\u306f\u3001\u653e\u5c04\u5149\u3092\u7528\u3044\u305fX\u7dda\u30de\u30a4\u30af\u30ed\u30c8\u30e2\u30b0\u30e9\u30d5\u30a3\u30fc\u3068Golgi-Cox\u542b\u6d78\u30d7\u30ed\u30c8\u30b3\u30eb\u3092\u7d44\u307f\u5408\u308f\u305b\u305f\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u65b9\u6cd5\u3092\u767a\u8868\u3057\u3066\u3044\u307e\u3059\u3002 <\/p>\n\n\n\n<p>\u3053\u306e\u65b9\u6cd5\u3067\u306f\u3001\u7d44\u7e54\u5185\u306b\u6bd4\u8f03\u7684\u307e\u3070\u3089\u306b\u5206\u5e03\u3059\u308b\u5168\u795e\u7d4c\u7d30\u80de\u3092\u3001\u3088\u308a\u9ad8\u304f\u5747\u8cea\u306a\u30b3\u30f3\u30c8\u30e9\u30b9\u30c8\u3067\u89b3\u5bdf\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u8133\u306fGolgi-Cox\u67d3\u8272\u6db2\u4e2d\u306714\u65e5\u9593\u3001\u906e\u5149\u3057\u3066\u30a4\u30f3\u30ad\u30e5\u30d9\u30fc\u30c8\u3057\u305f\u3002\u57f9\u990a\u671f\u9593\u5f8c\u3001\u8133\u3092\u30d3\u30d6\u30e9\u30c8\u30fc\u30e0\u3067\u9023\u7d9a\u7684\u306b\u5207\u308a\u51fa\u3057\u305f\u3002<\/strong><\/p>\n\n\n\n<p>\u3092\u78ba\u8a8d\u3057\u307e\u3059\u3002 <a href=\"https:\/\/www.nature.com\/articles\/s41598-018-30501-x\" target=\"_blank\" rel=\"noreferrer noopener\">\u30aa\u30ea\u30b8\u30ca\u30eb\u8a18\u4e8b\u306f\u3053\u3061\u3089<\/a>.<\/p>\n\n\n\n<h2><strong>\u30b0\u30e9\u30d5\u30a3\u30ab\u30eb\u30a2\u30d6\u30b9\u30c8\u30e9\u30af\u30c8 powered by Mind the Graph<\/strong><\/h2>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/neuronal-image.webp\"><img decoding=\"async\" loading=\"lazy\" width=\"914\" height=\"1024\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/neuronal-image-914x1024.webp\" alt=\"\" class=\"wp-image-20263\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/neuronal-image-914x1024.webp 914w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/neuronal-image-268x300.webp 268w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/neuronal-image-768x860.webp 768w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/neuronal-image-1371x1536.webp 1371w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/neuronal-image-11x12.webp 11w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/neuronal-image-89x100.webp 89w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/neuronal-image.webp 1500w\" sizes=\"(max-width: 914px) 100vw, 914px\" \/><\/a><figcaption class=\"wp-element-caption\"><em>\u3067\u4f5c\u3089\u308c\u3066\u3044\u307e\u3059\u3002 <a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>\u8457\u8005\u304c\u4f7f\u7528\u3057\u305f\u306e\u306f <a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a> \u6210\u4f53\u30de\u30a6\u30b9\u306b\u751f\u7406\u98df\u5869\u6c34\u307e\u305f\u306f\u30d4\u30ed\u30ab\u30eb\u30d4\u30f3\u6eb6\u6db2\uff08280mg\/kg\uff09\u3092i.p.\u6295\u4e0e\u3059\u308b\u69d8\u5b50\u3092\u6a21\u5f0f\u7684\u306b\u8868\u73fe\u3057\u305f\u30a4\u30e9\u30b9\u30c8\u30ec\u30fc\u30b7\u30e7\u30f3\u3092\u4f5c\u6210\u3057\u307e\u3057\u305f\u3002\u8907\u96d1\u306a\u30d7\u30ed\u30bb\u30b9\u3092\u30a4\u30f3\u30d5\u30a9\u30b0\u30e9\u30d5\u30a3\u30c3\u30af\u30b9\u3067\u8868\u73fe\u3059\u308b\u3053\u3068\u306f\u3001\u8a73\u7d30\u3084\u91cd\u8981\u306a\u60c5\u5831\u3092\u7701\u304f\u3053\u3068\u306a\u304f\u3001\u5bb9\u6613\u306b\u7406\u89e3\u3067\u304d\u308b\u3088\u3046\u306b\u3059\u308b\u826f\u3044\u65b9\u6cd5\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u4eca\u56de\u306e\u7814\u7a76\u6210\u679c\u306f\u3001\u3053\u306e\u9818\u57df\u306b\u3064\u3044\u3066\u3053\u308c\u307e\u3067\u77e5\u3089\u308c\u3066\u3044\u305f\u3053\u3068\u3092\u6574\u7406\u3059\u308b\u3082\u306e\u3067\u3042\u308b\u3068\u601d\u308f\u308c\u308b\u3002\u300c\u6c34\u9280\u3092\u7528\u3044\u305f\u795e\u7d4c\u7d30\u80de\u3078\u306e\u542b\u6d78\u306b\u3088\u308a\u3001\u7d30\u80de\u3078\u306e\u542b\u6d78\u304c\u3088\u308a\u9023\u7d9a\u7684\u304b\u3064\u5747\u8cea\u306b\u306a\u308a\u3001\u30a2\u30fc\u30c1\u30d5\u30a1\u30af\u30c8\u306e\u5bc6\u5ea6\u3082\u5927\u5e45\u306b\u6e1b\u5c11\u3057\u305f\u305f\u3081\u3001\u4e3b\u306b\u795e\u7d4c\u7d30\u80de\u5168\u4f53\u3092\u660e\u78ba\u306b\u5b9a\u7fa9\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3057\u305f\u300d\u3068\u3001de Castro Fonseca\u306f\u793a\u5506\u3057\u305f\u3002<\/p>\n\n\n\n<h2><strong>\u8ad6\u6587\u30a4\u30f3\u30d1\u30af\u30c8\u3068\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9<\/strong><\/h2>\n\n\n\n<p>\u3067\u5206\u6790\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002 <a href=\"https:\/\/mindthegraph.com\/blog\/altmetric\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u30a2\u30eb\u30c8\u30e1\u30c8\u30ea\u30c3\u30af<\/a> \u672c\u8ad6\u6587\u306e\u30aa\u30f3\u30e9\u30a4\u30f3\u6ce8\u76ee\u5ea6\u304c\u9ad8\u3044\u3068\u3044\u3046\u30c7\u30fc\u30bf <strong>\u3088\u308a <strong>64%<\/strong><\/strong> <strong>\u306f\u3001Scientific Reports\u306b\u63b2\u8f09\u3055\u308c\u305f\u540c\u5e74\u4ee3\u306e\u4ed6\u306e\u5168\u8ad6\u6587\u306e\u3046\u3061<\/strong><\/p>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/high-resolution.png\"><img decoding=\"async\" loading=\"lazy\" width=\"361\" height=\"150\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/high-resolution.png\" alt=\"\" class=\"wp-image-20262\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/high-resolution.png 361w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/high-resolution-300x125.png 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/high-resolution-18x7.png 18w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/high-resolution-100x42.png 100w\" sizes=\"(max-width: 361px) 100vw, 361px\" \/><\/a><figcaption class=\"wp-element-caption\"><em>\u51fa\u5178 <a href=\"https:\/\/www.nature.com\/articles\/s41598-018-30501-x\/metrics\" target=\"_blank\" rel=\"noreferrer noopener\">\u30a2\u30eb\u30c8\u30e1\u30c8\u30ea\u30af\u30b9<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>\u30a4\u30f3\u30d5\u30a9\u30b0\u30e9\u30d5\u30a3\u30c3\u30af\u306e\u529b\u3082\u501f\u308a\u3066\u3001\u8a18\u4e8b\u306e\u30a2\u30af\u30bb\u30b7\u30d3\u30ea\u30c6\u30a3\u3092\u5411\u4e0a\u3055\u305b\u307e\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<div class=\"is-layout-flex wp-block-buttons\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-background wp-element-button\" href=\"https:\/\/mindthegraph.com\/app\/auth\/register?from_url=\/\" style=\"border-radius:100px;background-color:#dc1866\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Mind the Graph\u3092\u8a66\u3059<\/strong><\/a><\/div>\n<\/div>\n\n\n\n<div style=\"height:46px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Mind the Graph\u306e\u30a4\u30e9\u30b9\u30c8\u3067\u8868\u73fe\u3055\u308c\u305f\u8133\u306e\u7d30\u80de\u69cb\u9020\u3068\u7d50\u5408\u6027\u3092\u8aad\u307f\u89e3\u304f\u65b0\u3057\u3044\u65b9\u6cd5\u3092\u3054\u89a7\u304f\u3060\u3055\u3044\u3002<\/p>","protected":false},"author":29,"featured_media":20013,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[195,958,957,960,1],"tags":[96,554,775,963],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>High-resolution synchrotron-based X-ray microtomography as a tool to unveil the three-dimensional neuronal architecture of the brain Paper Review - Mind the Graph Blog<\/title>\n<meta name=\"description\" content=\"Look into the new method for deciphering the cytoarchitecture and connectivity of the brain represented with Mind the Graph&#039;s illustrations.\" \/>\n<meta name=\"robots\" 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