{"id":13152,"date":"2021-07-19T19:11:20","date_gmt":"2021-07-19T22:11:20","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=13152"},"modified":"2023-01-05T14:31:40","modified_gmt":"2023-01-05T17:31:40","slug":"cannabis-bioavailability-all-you-need-to-know","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/ja\/%e5%a4%a7%e9%ba%bb%e3%81%ae%e3%83%90%e3%82%a4%e3%82%aa%e3%82%a2%e3%83%99%e3%82%a4%e3%83%a9%e3%83%93%e3%83%aa%e3%83%86%e3%82%a3%e3%81%ab%e3%81%a4%e3%81%84%e3%81%a6\/","title":{"rendered":"\u5927\u9ebb\u306e\u30d0\u30a4\u30aa\u30a2\u30d9\u30a4\u30e9\u30d3\u30ea\u30c6\u30a3\uff1a\u77e5\u3063\u3066\u304a\u304f\u3079\u304d\u3059\u3079\u3066\u306e\u3053\u3068"},"content":{"rendered":"<p>\u5927\u9ebb\u306e\u30d0\u30a4\u30aa\u30a2\u30d9\u30a4\u30e9\u30d3\u30ea\u30c6\u30a3\u3068P450\u30c1\u30c8\u30af\u30ed\u30fc\u30e0\u30fb\u30ab\u30f3\u30ca\u30d3\u30ce\u30a4\u30c9\u306e\u4ee3\u8b1d\u306b\u3064\u3044\u3066\u79d1\u5b66\u304c\u4f55\u3092\u8a00\u3063\u3066\u3044\u308b\u304b\u3092\u77e5\u308a\u305f\u3044\u306a\u3089\u3001\u3053\u306e\u8a18\u4e8b\u306f\u3042\u306a\u305f\u306e\u305f\u3081\u306e\u3082\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u5927\u9ebb\u3092\u4f7f\u3063\u305f\u85ac\u306b\u95a2\u3057\u3066\u306f\u3001\u307e\u3060\u30c7\u30fc\u30bf\u304c\u5c11\u306a\u3044\u306e\u3067\u3059\u304c\u3001\u7814\u7a76\u306b\u3088\u3063\u3066\u3001\u79d1\u5b66\u8005\u306f\u3059\u3067\u306b\u52b9\u7387\u3001\u5b89\u5168\u6027\u3001\u85ac\u7269\u76f8\u4e92\u4f5c\u7528\u3092\u4e88\u6e2c\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u30ab\u30f3\u30ca\u30d3\u30ce\u30a4\u30c9\u306e\u6cbb\u7642\u3084\u30ab\u30f3\u30ca\u30d3\u30ce\u30a4\u30c9\u305d\u306e\u3082\u306e\u306b\u3064\u3044\u3066\u306f\u3001\u305d\u308c\u307b\u3069\u65ad\u5b9a\u7684\u306a\u7d50\u679c\u306f\u51fa\u3066\u3044\u307e\u305b\u3093\u304c\u3001\u751f\u6d3b\u306e\u8cea\u304c\u5411\u4e0a\u3057\u305f\u3068\u3044\u3046\u6c7a\u5b9a\u7684\u306a\u30dd\u30b8\u30c6\u30a3\u30d6\u306a\u7d50\u679c\u304c\u7814\u7a76\u306b\u3088\u3063\u3066\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002&nbsp;<\/p>\n\n\n\n<p>\u7d4c\u53e3\u6295\u4e0e\u3055\u308c\u305f\u85ac\u306f\u3001\u307e\u305a\u4f53\u5185\u306e\u9175\u7d20\u3067\u4ee3\u8b1d\u3055\u308c\u307e\u3059\u304c\u3001\u3053\u308c\u306f\u85ac\u7269\u6cbb\u7642\u52b9\u679c\u306b\u76f4\u63a5\u5f71\u97ff\u3059\u308b\u91cd\u8981\u306a\u30b9\u30c6\u30c3\u30d7\u3067\u3059\u3002&nbsp;<\/p>\n\n\n\n<p class=\"has-text-align-center\">\u30c1\u30a7\u30c3\u30af\u3059\u308b&nbsp;<a href=\"https:\/\/mindthegraph.com\/app\/illustrations\">Mind the Graph \u30ae\u30e3\u30e9\u30ea\u30fc<\/a>&nbsp;\u3053\u306e\u30d6\u30ed\u30b0\u8a18\u4e8b\u306e\u30c6\u30fc\u30de\u306b\u95a2\u9023\u3059\u308b\u30a4\u30e9\u30b9\u30c8\u3092\u63b2\u8f09\u3057\u3066\u3044\u307e\u3059\u3002\u4e0b\u306e\u753b\u50cf\u3092\u30af\u30ea\u30c3\u30af\u3057\u3066\u304f\u3060\u3055\u3044<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2021\/07\/botanica-e-bioquimica.jpg\" target=\"_blank\" rel=\"https:\/\/mindthegraph.com\/app\/illustrations?search=botany,%20biochemistry noopener\"><img decoding=\"async\" loading=\"lazy\" width=\"1024\" height=\"744\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2021\/07\/botanica-e-bioquimica-1024x744.jpg\" alt=\"\u30b0\u30e9\u30d5\u30ae\u30e3\u30e9\u30ea\u30fc\u8abf\u3079\" class=\"wp-image-13154\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2021\/07\/botanica-e-bioquimica-1024x744.jpg 1024w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2021\/07\/botanica-e-bioquimica-300x218.jpg 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2021\/07\/botanica-e-bioquimica-768x558.jpg 768w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2021\/07\/botanica-e-bioquimica.jpg 1137w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure><\/div>\n\n\n<h2>\u30b7\u30c8\u30af\u30ed\u30e0P450\u9175\u7d20\u30b9\u30fc\u30d1\u30fc\u30d5\u30a1\u30df\u30ea\u30fc <\/h2>\n\n\n\n<p>\u3068\u3044\u3046\u9175\u7d20\u306e\u30b9\u30fc\u30d1\u30fc\u30d5\u30a1\u30df\u30ea\u30fc\u304c\u3042\u308a\u307e\u3059\u3002 <strong><em>\u30c1\u30c8\u30af\u30ed\u30fc\u30e0P450<\/em><\/strong> - CYP\u306f\u3001\u5927\u9ebb\u3092\u542b\u3080\u69d8\u3005\u306a\u85ac\u7269\u306e\u7b2c\u4e00\u76f8\u4ee3\u8b1d\u3092\u62c5\u3046\u9175\u7d20\u7fa4\u3067\u3059\u3002&nbsp;<\/p>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u9175\u7d20\u306f\u3001\u4e3b\u306b\u809d\u81d3\u306b\u5b58\u5728\u3057\u3001\u814e\u81d3\u3001\u76ae\u819a\u3001\u6d88\u5316\u7ba1\u3001\u305d\u3057\u3066\u80ba\u306b\u3082\u5b58\u5728\u3059\u308b\u3002&nbsp;<\/p>\n\n\n\n<p>CYP\u9175\u7d20\u306f\u3001\u85ac\u7269\u306e\u6d3b\u6027\u90e8\u4f4d\u3092\u9178\u5316\u3057\u3066\u751f\u4f53\u5185\u5909\u63db\u3092\u884c\u3046\u3053\u3068\u3067\u4f5c\u7528\u3057\u307e\u3059\u3002&nbsp;&nbsp;<\/p>\n\n\n\n<p>\u7b2c\u4e8c\u306e\u9175\u7d20\u30d5\u30a1\u30df\u30ea\u30fc\u306f\u3001\u3053\u308c\u3082\u91cd\u8981\u3067\u3042\u308b\u3002 <strong>\u751f\u5316\u7cd6<\/strong>\u306e\u7565\u79f0\u3067\u3059\u3002 <em>\u30a6\u30ea\u30b8\u30f35<\/em>\u2032-<em>\u30ea\u30f3\u5316\u6c34\u7d20<\/em>&#8211;<em>\u30b0\u30eb\u30af\u30ed\u30ce\u30b7\u30eb\u30c8\u30e9\u30f3\u30b9\u30d5\u30a7\u30e9\u30fc\u30bc<\/em>.&nbsp;<\/p>\n\n\n\n<p>\u3064\u307e\u308a\u3001\u3053\u306e\u9175\u7d20\u304c\u7269\u8cea\u306e\u69cb\u9020\u3092\u5909\u5316\u3055\u305b\u3001\u5c3f\u4e2d\u306b\u6392\u6cc4\u3055\u308c\u3084\u3059\u304f\u3057\u3066\u3044\u308b\u306e\u3067\u3059\u3002&nbsp;<\/p>\n\n\n\n<p>\u3055\u3089\u306b\u3001\u3053\u306e2\u3064\u306e\u9175\u7d20\u7fa4\u306f\u3001\u305d\u306e\u6d3b\u6027\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u30e1\u30ab\u30cb\u30ba\u30e0\u3068\u3057\u3066\u3001\u963b\u5bb3\u3068\u8a98\u5c0e\u306e2\u7a2e\u985e\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3><strong>\u9175\u7d20\u963b\u5bb3<\/strong><\/h3>\n\n\n\n<p>\u9175\u7d20\u963b\u5bb3\u306f\u30012\u3064\u306e\u85ac\u3092\u540c\u6642\u306b\u670d\u7528\u3057\u3001\u540c\u3058\u4ee3\u8b1d\u7d4c\u8def\u3092\u5171\u6709\u3057\u3001\u5438\u53ce\u3055\u308c\u308b\u305f\u3081\u306b\u540c\u3058\u9175\u7d20\u3092\u9023\u7d9a\u3057\u3066\u5fc5\u8981\u3068\u3059\u308b\u5834\u5408\u306b\u8d77\u3053\u308a\u307e\u3059\u3002&nbsp;<\/p>\n\n\n\n<p>\u3057\u305f\u304c\u3063\u3066\u30012\u3064\u306e\u7570\u306a\u308b\u85ac\u5264\u304c\u540c\u3058\u9175\u7d20\u90e8\u4f4d\u3067\u7af6\u5408\u3059\u308b\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002&nbsp;<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001\u4eba\u304c\u305f\u304f\u3055\u3093\u3044\u308b\u5e97\u306b\u884c\u3063\u3066\u3082\u3001\u5e97\u54e1\u306f\u4e00\u4eba\u3057\u304b\u304a\u3089\u305a\u3001\u5e97\u5185\u306e\u3059\u3079\u3066\u306e\u4eba\u3092\u52a9\u3051\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002\u5f7c\u5973\uff0f\u5f7c\u306e\u6ce8\u610f\u3092\u5f15\u304f\u306e\u304c\u3069\u308c\u307b\u3069\u96e3\u3057\u3044\u304b\u3001\u60f3\u50cf\u3067\u304d\u307e\u3059\u304b\uff1f\u7d50\u5c40\u3001\u4f55\u4eba\u304b\u306e\u9867\u5ba2\u306f\u3042\u304d\u3089\u3081\u3001\u4ed6\u306e\u9867\u5ba2\u306f\u5e97\u54e1\u3068\u8a71\u3059\u305f\u3081\u306b\u5217\u3092\u306a\u3057\u3066\u5f85\u3064\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002\u4eca\u5ea6\u306f\u3001\u5e97\u54e1\u3092\u9175\u7d20\u306b\u3001\u30af\u30e9\u30a4\u30a2\u30f3\u30c8\u3092\u85ac\u7269\u7269\u8cea\u306b\u5909\u3048\u3066\u3001\u5e97\u54e1\u306e\u6ce8\u610f\u3092\u5f15\u304f\u306e\u306f\u9175\u7d20\u306e\u30b5\u30a4\u30c8\u3092\u5229\u7528\u3059\u308b\u3053\u3068\u306b\u3057\u307e\u3057\u3087\u3046\u3002&nbsp;<\/p>\n\n\n\n<p>\u307e\u3042\u3001\u79c1\u306f\u300c\u3042\u304d\u3089\u3081\u3066\u5e30\u308b\u300d\u3068\u3044\u3046\u30c1\u30fc\u30e0\u306a\u306e\u3067\u3059\u304c\u3001\u9175\u7d20\u306e\u4e16\u754c\u3067\u306f\u3053\u306e\u30c1\u30fc\u30e0\u306f\u5b58\u5728\u305b\u305a\u3001\u3059\u3079\u3066\u306e\u7269\u8cea\u306f\u300c\u53c2\u52a0\u5f85\u3061\u300d\u3067\u3042\u308a\u3001\u305d\u306e\u305f\u3081\u306b\u3059\u3079\u3066\u306e\u85ac\u7269\u7269\u8cea\u306f\u6b21\u306e\u9175\u7d20\u306e\u5229\u7528\u53ef\u80fd\u90e8\u4f4d\u3092\u5f85\u3063\u3066\u7acb\u3063\u3066\u3044\u308b\u306e\u3067\u3059\u3002&nbsp;<\/p>\n\n\n\n<p>\u7d50\u5c40\u3001\u6291\u5236\u4f5c\u7528\u306b\u3088\u3063\u3066\u3001\u60a3\u8005\u3055\u3093\u306e\u8840\u6f3f\u4e2d\u306e\u85ac\u7269\u6fc3\u5ea6\u304c\u4e0a\u6607\u3057\u3001\u6bd2\u6027\u84c4\u7a4d\u306b\u3064\u306a\u304c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001UGTs\u9175\u7d20\u306e\u963b\u5bb3\u306b\u3088\u308a\u85ac\u7269\u306e\u6392\u6cc4\u304c\u4f4e\u4e0b\u3057\u3001\u4f53\u5185\u306b\u84c4\u7a4d\u3055\u308c\u308b\u3053\u3068\u304c\u6319\u3052\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u963b\u5bb3\u4f5c\u7528\u304c\u8d77\u3053\u308b\u306b\u306f\u30012\u3064\u306e\u85ac\u7269\u306e\u3046\u3061\u4e00\u65b9\u304c\u963b\u5bb3\u5264\u3068\u306a\u308a\u3001\u3059\u3079\u3066\u306e\u9175\u7d20\u30b5\u30a4\u30c8\u3092\u652f\u914d\u3057\u3001\u3082\u3046\u4e00\u65b9\u306e\u85ac\u7269\u304c\u7d50\u5408\u3067\u304d\u306a\u3044\u9175\u7d20\u30b5\u30a4\u30c8\u306b\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002&nbsp;<\/p>\n\n\n\n<p>\u3057\u305f\u304c\u3063\u3066\u3001\u963b\u5bb3\u3055\u308c\u305f\u85ac\u7269\u306f\u3001\u305d\u306e\u5438\u53ce\u7387\u304c\u975e\u5e38\u306b\u4f4e\u3044\u30ec\u30d9\u30eb\u306b\u307e\u3067\u4f4e\u4e0b\u3057\u3001\u305d\u306e\u7d50\u679c\u3001\u85ac\u7269\u306f\u8840\u6f3f\u4e2d\u306b\u300c\u6ede\u7559\u300d\u3057\u3001\u6bd2\u6027\u30ec\u30d9\u30eb\u3067\u306e\u30d0\u30a4\u30aa\u30a2\u30d9\u30a4\u30e9\u30d3\u30ea\u30c6\u30a3\u3092\u5897\u52a0\u3055\u305b\u308b\u3002&nbsp;&nbsp;<\/p>\n\n\n\n<h3><strong>\u9175\u7d20\u306e\u8a98\u5c0e&nbsp;<\/strong><\/h3>\n\n\n\n<p>\u4e00\u65b9\u3001\u9175\u7d20\u8a98\u5c0e\u904e\u7a0b\u3067\u306f\u3001\u305d\u306e\u9006\u306e\u3053\u3068\u304c\u8d77\u3053\u308b\u3002\u4e00\u65b9\u306e\u85ac\u7269\u304c\u4ed6\u65b9\u306e\u85ac\u7269\u3092\u5438\u53ce\u3059\u308b\u9175\u7d20\u306e\u50c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<strong>\u30d5\u30eb\u30b9\u30da\u30af\u30c8\u30e9\u30e0<\/strong> \u306e\u3088\u3046\u306b1\u3064\u306e\u6210\u5206\u3060\u3051\u3067\u69cb\u6210\u3055\u308c\u3066\u3044\u308b\u3082\u306e\u3068\u3001CBD\u306e\u3088\u3046\u306b1\u3064\u306e\u6210\u5206\u3060\u3051\u3092\u5206\u96e2\u3057\u3066\u69cb\u6210\u3055\u308c\u3066\u3044\u308b\u3082\u306e\u304c\u3042\u308a\u307e\u3059\u3002&nbsp;<\/p>\n\n\n\n<p>\u3082\u3061\u308d\u3093\u3001CBD\u3067\u69cb\u6210\u3055\u308c\u308b\u3082\u306e\u306e\u3088\u3046\u306b\u3001\u305d\u306e\u9593\u306b\u30d0\u30ea\u30a8\u30fc\u30b7\u30e7\u30f3\u304c\u3042\u308a\u307e\u3059\u3002\u3082\u3061\u308d\u3093\u3001CBD\u3068THC\u3092\u7279\u5b9a\u306e\u6bd4\u7387\u3067\u914d\u5408\u3057\u305f\u3082\u306e\u3084\u3001CBD\u3092\u4ed6\u306e\u690d\u7269\u6210\u5206\u304b\u3089\u5b8c\u5168\u306b\u5206\u96e2\u3057\u3066\u3044\u306a\u3044\u3082\u306e\u306a\u3069\u3001\u3055\u307e\u3056\u307e\u306a\u30d0\u30ea\u30a8\u30fc\u30b7\u30e7\u30f3\u304c\u3042\u308a\u307e\u3059\u3002&nbsp;<\/p>\n\n\n\n<p>CBD\u306f\u30ab\u30f3\u30ca\u30d3\u30ce\u30a4\u30c9\u306e\u7814\u7a76\u5bfe\u8c61\u3068\u3057\u3066\u6700\u3082\u983b\u5ea6\u304c\u9ad8\u3044\u305f\u3081\u3001\u7d50\u679c\u3068\u3057\u3066\u3001\u3088\u308a\u591a\u304f\u306e\u60c5\u5831\u304c\u5f97\u3089\u308c\u308b\u30ab\u30f3\u30ca\u30d3\u30ce\u30a4\u30c9\u3068\u8a00\u3048\u307e\u3059\u3002&nbsp;<\/p>\n\n\n\n<p>\u767a\u8868\u3055\u308c\u305f\u7814\u7a76\u306e\u591a\u304f\u306f\u3001CBD\u6cbb\u7642\u3092\u53d7\u3051\u305f\u60a3\u8005\u306e\u6539\u5584\u3092\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u304c\u3001\u3054\u304f\u4e00\u90e8\u306e\u7814\u7a76\u3067\u306f\u6c7a\u5b9a\u7684\u306a\u7d50\u679c\u304c\u5f97\u3089\u308c\u3066\u304a\u3089\u305a\u3001\u60a3\u8005\u306e\u60aa\u5316\u3092\u5831\u544a\u3057\u3066\u3044\u308b\u3082\u306e\u3055\u3048\u3042\u308b\u306e\u3067\u3059\u3002&nbsp;<\/p>\n\n\n\n<p>CBD\u6cbb\u7642\u306b\u3088\u308a\u6539\u5584\u3055\u308c\u305f\u60a3\u8005\u306e\u75c7\u72b6\u3084\u72b6\u614b\u306b\u306f\u3001\u767a\u4f5c\u3001\u75db\u307f\u3001\u764c\u3001\u708e\u75c7\u3001\u4e0d\u5b89\u3001\u795e\u7d4c\u5909\u6027\u3001\u591a\u767a\u6027\u786c\u5316\u75c7\u3001\u3046\u3064\u75c5\u306a\u3069\u304c\u3042\u308a\u307e\u3059\u3002&nbsp;<\/p>\n\n\n\n<h2><strong>\u30ab\u30f3\u30ca\u30d3\u30ce\u30a4\u30c9\u306b\u95a2\u9023\u3059\u308bP450\u30a2\u30a4\u30bd\u30d5\u30a9\u30fc\u30e0\u306b\u3064\u3044\u3066<\/strong><\/h2>\n\n\n\n<p>CBD\u306e\u4ee3\u8b1d\u306f\u3001P450\u30d5\u30a1\u30df\u30ea\u30fc\u306e2\u3064\u306e\u4e3b\u8981\u306a\u9175\u7d20\u3001\u30a2\u30a4\u30bd\u30d5\u30a9\u30fc\u30e0CYP3A4\u3068CYP2C19\u306b\u3088\u3063\u3066\u884c\u308f\u308c\u308b\u3053\u3068\u304c\u65e2\u306b\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002&nbsp;<\/p>\n\n\n\n<p>\u4ed6\u306e\u85ac\u7269\u3068\u540c\u69d8\u306b\u3001CBD\u306e\u30d0\u30a4\u30aa\u30a2\u30d9\u30a4\u30e9\u30d3\u30ea\u30c6\u30a3\u3082\u3001\u963b\u5bb3\u5264\u3084\u8a98\u5c0e\u5264\u306b\u3055\u3089\u3055\u308c\u308b\u3068\u5909\u5316\u3057\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002&nbsp;<\/p>\n\n\n\n<p>\u3055\u3089\u306b\u3001CBD\u306f\u30a2\u30a4\u30bd\u30d5\u30a9\u30fc\u30e03A4\u30012C9\u30012C19\u30011A2\u30012C8\u30012B6\u30012E1\u306b\u3088\u3063\u3066\u3082\u4ee3\u8b1d\u3055\u308c\u307e\u3059\u304c\u3001\u305d\u306e\u91cf\u306f\u304b\u306a\u308a\u5c11\u306a\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002&nbsp;<\/p>\n\n\n\n<p>\u305d\u306e\u305f\u3081\u3001CBD\u306f\u963b\u5bb3\u5264\u53ca\u3073\uff0f\u53c8\u306f\u6291\u5236\u5264\u3068\u3057\u3066\u4f5c\u7528\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3002CBD\u306b\u3088\u3063\u3066\u963b\u5bb3\u3055\u308c\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u9175\u7d20\u306b\u306f\u3001CYP2C19\u3001CYP2D6\u3001CYP2C9\u3001\u304a\u3088\u3073CYP2C8\u304c\u3042\u308a\u307e\u3059\u3002&nbsp;<\/p>\n\n\n\n<p>UGT\u30d5\u30a1\u30df\u30ea\u30fc\u3067\u306f\u3001CBD\u306fUGT1A9\u3068UGT2B7\u3068\u3044\u3046\u9175\u7d20\u3092\u963b\u5bb3\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u3044\u304f\u3064\u304b\u306eCBD\u4ee3\u8b1d\u7269\u3067\u3055\u3048\u3001\u963b\u5bb3\u5264\u3068\u3057\u3066\u4f5c\u7528\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n\n<p>THC\u306e\u963b\u5bb3\u30fb\u8a98\u5c0e\u4f5c\u7528\u306b\u3064\u3044\u3066\u306f\u3042\u307e\u308a\u60c5\u5831\u304c\u3042\u308a\u307e\u305b\u3093\u304c\u3001\u5f53\u8a72\u30ab\u30f3\u30ca\u30d3\u30ce\u30a4\u30c9\u306fCYP2C9\u3068CYP3A4\u3068\u3044\u3046\u9175\u7d20\u3067\u4ee3\u8b1d\u3055\u308c\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002&nbsp;<\/p>\n\n\n\n<p>\u3057\u305f\u304c\u3063\u3066\u3001\u3053\u308c\u3089\u306e\u9175\u7d20\u306e\u5408\u6210\u304c\u4f4e\u3044\u304b\u4e0d\u5341\u5206\u3067\u3042\u308b\u3053\u3068\u3092\u7279\u5fb4\u3068\u3059\u308b\u907a\u4f1d\u5b50\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u3092\u6301\u3064\u4eba\u3005\u306f\u3001THC\u306e\u30d0\u30a4\u30aa\u30a2\u30d9\u30a4\u30e9\u30d3\u30ea\u30c6\u30a3\u304c\u901a\u5e38\u306e\u30ec\u30d9\u30eb\u3088\u308a\u30823\u500d\u9ad8\u304f\u3001\u306f\u308b\u304b\u306b''\u3092\u6709\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3042\u308b\u3002<em>\u304a\u9ad8\u3044<\/em> THC\u306e\u7d4c\u9a13 - \u30c0\u30b8\u30e3\u30ec\u3092\u5f97\u305f\uff1f- \u305d\u308c\u306f\u3001CBD\u306e\u52b9\u679c\u306b\u3082\u95a2\u4fc2\u3057\u307e\u3059\u3002&nbsp;<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2021\/07\/preview-317800-1.png\"><img decoding=\"async\" loading=\"lazy\" width=\"1024\" height=\"768\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2021\/07\/preview-317800-1-1024x768.png\" alt=\"Mind the Graph\u3092\u4f7f\u7528\u3057\u3066\u4f5c\u6210\u3057\u305f\u30a4\u30f3\u30d5\u30a9\u30b0\u30e9\u30d5\u30a3\u30c3\u30af\u3067\u3059\u3002\" class=\"wp-image-13153\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2021\/07\/preview-317800-1-1024x768.png 1024w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2021\/07\/preview-317800-1-300x225.png 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2021\/07\/preview-317800-1-768x576.png 768w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2021\/07\/preview-317800-1-1536x1152.png 1536w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2021\/07\/preview-317800-1-2048x1536.png 2048w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure>\n\n\n\n<h3><strong>\u6b63\u3057\u3044\u7528\u6cd5\u30fb\u7528\u91cf\u306e\u9078\u629e&nbsp;<\/strong><\/h3>\n\n\n\n<p>\u6700\u5f8c\u306b\u3001\u5927\u9ebb\u306e\u79d1\u5b66\u8005\u304cCBD\u306f\u4e0d\u5b89\u3092\u6271\u3046\u60a3\u8005\u3092\u52a9\u3051\u308b\u3068\u65ad\u8a00\u3057\u3066\u3082\u3001\u9078\u629e\u3055\u308c\u305f\u7528\u91cf\u3067\u6ce8\u610f\u6df1\u304f\u898b\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u3002&nbsp;<\/p>\n\n\n\n<p>\u3069\u3046\u3084\u3089\u3001CBD\u306b\u306f\u4e8c\u76f8\u6027\u52b9\u679c\u304c\u3042\u308b\u3088\u3046\u3067\u3001\u4f4e\u7528\u91cf\u3067\u306f\u78ba\u304b\u306b\u6297\u4e0d\u5b89\u4f5c\u7528\u304c\u3042\u308a\u3001\u4e0d\u5b89\u30ec\u30d9\u30eb\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002&nbsp;<\/p>\n\n\n\n<p>\u3057\u304b\u3057\u3001\u3042\u308b\u91cf\u3092\u8d85\u3048\u308b\u3068\u3001\u30ab\u30f3\u30ca\u30d3\u30ce\u30a4\u30c9\u306f\u5168\u304f\u7570\u306a\u308b\u52b9\u679c\u3092\u767a\u63ee\u3059\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3059\u3002\u9ad8\u7528\u91cf\u306eCBD\u306f\u9006\u52b9\u679c\u3092\u5f15\u304d\u8d77\u3053\u3057\u3001\u4e0d\u5b89\u30ec\u30d9\u30eb\u3092\u9ad8\u3081\u308b\u4e0d\u5b89\u8a98\u767a\u6027\u306b\u306a\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002&nbsp;<\/p>\n\n\n\n<p>\u305d\u306e\u305f\u3081\u3001\u60a3\u8005\u3055\u3093\u306e\u30cb\u30fc\u30ba\u306b\u5408\u3063\u305f\u9069\u5207\u306a\u7528\u91cf\u3092\u898b\u3064\u3051\u308b\u3053\u3068\u304c\u3001\u6700\u9ad8\u306e\u6cbb\u7642\u52b9\u679c\u3092\u5f97\u308b\u305f\u3081\u306b\u4e0d\u53ef\u6b20\u3067\u3042\u308a\u3001\u6df1\u523b\u306a\u526f\u4f5c\u7528\u306a\u3057\u306b\u690d\u7269\u304c\u63d0\u4f9b\u3067\u304d\u308b\u53ef\u80fd\u6027\u3092\u8ffd\u6c42\u3057\u3066\u3044\u307e\u3059\u3002&nbsp;<\/p>\n\n\n\n<p>\u6295\u4e0e\u91cf\u306e\u9078\u629e\u3092\u8aa4\u308b\u3068\u3001\u93ae\u9759\u3001\u50be\u7720\u3001\u4e0b\u75e2\u3001\u98df\u6b32\u6e1b\u9000\u306a\u3069\u306e\u526f\u4f5c\u7528\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002&nbsp;<\/p>\n\n\n\n<p>\u526f\u4f5c\u7528\u306b\u3064\u3044\u3066\u306f\u3001Clinical Medicine Journal\u306b\u63b2\u8f09\u3055\u308c\u305f\u7814\u7a76\u3067\u3001\u60a3\u8005\u96c6\u56e3\u3067\u89b3\u5bdf\u3055\u308c\u305f\u3059\u3079\u3066\u306e\u526f\u4f5c\u7528\u306e\u30ea\u30b9\u30c8\u3068\u81e8\u5e8a\u8a66\u9a13\u7814\u7a76\u306e\u305d\u306e\u4ed6\u306e\u8a73\u7d30\u304c\u8a18\u8ff0\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u63b2\u8f09\u3055\u308c\u305f\u8ad6\u6587\u306f\u3053\u3061\u3089\u304b\u3089\u3054\u89a7\u3044\u305f\u3060\u3051\u307e\u3059\u3002 <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6678684\/\">\u3053\u308c<\/a>.&nbsp;<\/p>\n\n\n\n<p>\u5927\u9ebb\u3092\u539f\u6599\u3068\u3059\u308b\u533b\u85ac\u54c1\u306f\u3001\u3088\u308a\u4f4e\u3044\u30ea\u30b9\u30af\u3067\u53ef\u80fd\u6027\u3092\u793a\u3059\u4ed6\u306e\u533b\u85ac\u54c1\u3068\u540c\u69d8\u306b\u3001\u60a3\u8005\u304c\u53d7\u3051\u5165\u308c\u3001\u60a3\u8005\u304c\u5fc5\u8981\u3068\u3059\u308b\u3059\u3079\u3066\u306e\u60c5\u5831\u3092\u63d0\u4f9b\u3067\u304d\u308b\u5c02\u9580\u5bb6\u304c\u3064\u3044\u3066\u3044\u304f\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u5927\u9ebb\u3092\u4f7f\u3063\u305f\u85ac\u306b\u3064\u3044\u3066\u306e\u30b3\u30df\u30e5\u30cb\u30b1\u30fc\u30b7\u30e7\u30f3\u3092\u5171\u306b\u6539\u5584\u3057\u3001\u533b\u5e2b\u304c\u5927\u9ebb\u3092\u4ee3\u66ff\u7269\u3068\u3057\u3066\u6d3b\u7528\u3057\u3001\u8ab0\u3082\u304c\u5065\u5eb7\u3067\u5b89\u5168\u306a\u6cbb\u7642\u6cd5\u3092\u958b\u767a\u3067\u304d\u308b\u3088\u3046\u652f\u63f4\u3057\u307e\u3057\u3087\u3046\u3002&nbsp;<\/p>\n\n\n\n<p>\u3053\u306e\u8a18\u4e8b\u306f\u3044\u304b\u304c\u3067\u3057\u305f\u304b\uff1f\u5927\u9ebb\u306b\u95a2\u3059\u308b\u8a18\u4e8b\u3092\u3082\u3063\u3068\u8aad\u307f\u305f\u3044\u3067\u3059\u304b\uff1fMind the Grap\u306e\u30d6\u30ed\u30b0\u3067\u7d39\u4ecb\u3057\u3066\u3044\u308b\u5927\u9ebb\u306b\u95a2\u3059\u308b\u4ed6\u306e\u8a18\u4e8b\u3082\u30c1\u30a7\u30c3\u30af\u3057\u3066\u307f\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n\n<ul>\n<li><a href=\"https:\/\/mindthegraph.com\/blog\/cannabis-and-body-pain\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u5927\u9ebb\u3068\u4f53\u306e\u75db\u307f<\/a><\/li>\n<\/ul>\n\n\n\n<ul>\n<li><a href=\"https:\/\/mindthegraph.com\/blog\/terpenes-profile-cannabis-why-they-matter\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u5927\u9ebb\u306e\u30c6\u30eb\u30da\u30f3\u985e\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u3002\u306a\u305c\u91cd\u8981\u306a\u306e\u304b<\/a><\/li>\n<\/ul>\n\n\n\n<p><strong>\u53c2\u8003\u6587\u732e<\/strong><\/p>\n\n\n\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31288397\/\" target=\"_blank\" rel=\"noreferrer noopener\">BROWN, J. D.; WINTERSTEIN, A. G. Potential Adverse Drug Events and Drug-Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use\uff08\u533b\u7642\u304a\u3088\u3073\u6d88\u8cbb\u8005\u306e\u30ab\u30f3\u30ca\u30d3\u30b8\u30aa\u30fc\u30eb\uff08CBD\uff09\u4f7f\u7528\u306b\u3088\u308b\u6f5c\u5728\u7684\u306a\u85ac\u7269\u4e8b\u8c61\u3068\u85ac\u7269\u76f8\u4e92\u4f5c\u7528\uff09\u3002 <strong>\u81e8\u5e8a\u533b\u5b66\u96d1\u8a8c<\/strong>, v. 8, n. 7, 8 jul. 2019.&nbsp;<\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31909680\/\" target=\"_blank\" rel=\"noreferrer noopener\">DE FARIA, S. M. et al.\u30ab\u30f3\u30ca\u30d3\u30b8\u30aa\u30fc\u30eb\u6025\u6027\u6295\u4e0e\u306b\u3088\u308b\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u60a3\u8005\u306e\u6a21\u64ec\u30b9\u30d4\u30fc\u30c1\u30c6\u30b9\u30c8\u306b\u3088\u308b\u4e0d\u5b89\u3068\u632f\u6226\u3078\u306e\u5f71\u97ff\u3002 <strong>\u7cbe\u795e\u85ac\u7406\u5b66\u96d1\u8a8c<\/strong>34, n. 2, p. 189-196, 1 fev. 2020.&nbsp;<\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/www.researchgate.net\/publication\/333430376_Antioxidant_activity_and_evidence_for_synergism_of_Cannabis_sativa_Lessential_oil_with_antimicrobial_standards\" target=\"_blank\" rel=\"noreferrer noopener\">NAFIS, A. et al. Cannabis sativa (L.) \u7cbe\u6cb9\u306e\u6297\u9178\u5316\u6d3b\u6027\u3068\u6297\u83cc\u6a19\u6e96\u7269\u8cea\u3068\u306e\u76f8\u4e57\u4f5c\u7528\u306e\u8a3c\u62e0\u3002 <strong>\u5de5\u696d\u7528\u4f5c\u7269\u304a\u3088\u3073\u88fd\u54c1<\/strong>, v. 137, p. 396-400, 1 out.2019.&nbsp;<\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16389357\/\" target=\"_blank\" rel=\"noreferrer noopener\">OGU, C. C.; MAXA, J. L. \u30c1\u30c8\u30af\u30ed\u30fc\u30e0 P450 \u306b\u3088\u308b\u85ac\u7269\u76f8\u4e92\u4f5c\u7528\u3002 <strong>\u30d9\u30a4\u30e9\u30fc\u5927\u5b66\u30e1\u30c7\u30a3\u30ab\u30eb\u30bb\u30f3\u30bf\u30fc\u4f1a\u8b70\u9332<\/strong>13, n. 4, p. 421-423, out.2000.&nbsp;<\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31053391\/\" target=\"_blank\" rel=\"noreferrer noopener\">SAMANTA, D. Cannabidiol:\u3066\u3093\u304b\u3093\u306b\u304a\u3051\u308b\u81e8\u5e8a\u7684\u6709\u52b9\u6027\u3068\u5b89\u5168\u6027\u306e\u30ec\u30d3\u30e5\u30fc\u3002 <strong>\u5c0f\u5150\u795e\u7d4c\u5b66<\/strong>, v. 96, p. 24-29, 1 jul. 2019.&nbsp;<\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16439618\/\" target=\"_blank\" rel=\"noreferrer noopener\">ZHU, H.-J. et al. \u30de\u30ea\u30d5\u30a1\u30ca\u7531\u6765\u4e3b\u8981\u30ab\u30f3\u30ca\u30d3\u30ce\u30a4\u30c9\u306b\u3088\u308bP\u7cd6\u86cb\u767d\u8cea\u963b\u5bb3\u306e\u7279\u6027\u8a55\u4fa1\u3002 <strong>\u85ac\u7406\u5b66\u30fb\u5b9f\u9a13\u6cbb\u7642\u5b66\u96d1\u8a8c<\/strong>317, n. 2, p. 850-857, 1 maio 2006.&nbsp;<\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/canlivj.utpjournals.press\/doi\/full\/10.3138\/canlivj.2018-0023\" target=\"_blank\" rel=\"noreferrer noopener\">ZHU, J.; PELTEKIAN, K. M. Cannabis and the liver\uff08\u5927\u9ebb\u3068\u809d\u81d3\uff09\u3002\u77e5\u308a\u305f\u304b\u3063\u305f\u3051\u3069\u805e\u3051\u306a\u304b\u3063\u305f\u3053\u3068\u3002 <strong>\u30ab\u30ca\u30c0\u809d\u81d3\u5b66\u4f1a\u8a8c<\/strong>, v. 2, n. 3, p. 51-57, ago.2019.&nbsp;<\/a><\/p>\n\n\n\n<p>_____________________________________________________________________________________<\/p>\n\n\n\n<p>\u3042\u306a\u305f\u306f\u690d\u7269\u5b66\u7814\u7a76\u8005\u3067\u3059\u304b\uff1fMind the Graph\u3067\u306f\u3001\u690d\u7269\u5b66\u30a4\u30e9\u30b9\u30c8\u306e\u30ab\u30c6\u30b4\u30ea\u3092\u7528\u610f\u3057\u3066\u3044\u307e\u3059\u306e\u3067\u3001\u305c\u3072\u3054\u89a7\u304f\u3060\u3055\u3044\u3002 <a href=\"https:\/\/app.mindthegraph.com\/illustrations\/subcategory\/botany\">\u3053\u308c<\/a>!<\/p>\n\n\n\n<p>\u65b0\u3057\u3044\u30e6\u30fc\u30b6\u30fc\u3067\u3001\u30a4\u30e9\u30b9\u30c8\u3092\u4f7f\u7528\u3057\u3001\u30a4\u30f3\u30d5\u30a9\u30b0\u30e9\u30d5\u30a3\u30c3\u30af\u3084\u30d7\u30ec\u30bc\u30f3\u30c6\u30fc\u30b7\u30e7\u30f3\u306b\u8ffd\u52a0\u3057\u305f\u3044\u5834\u5408\u3001\u4eca\u3059\u3050\u59cb\u3081\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002 <a href=\"https:\/\/app.mindthegraph.com\/auth\/register\">\u3053\u3053\u3092\u30af\u30ea\u30c3\u30af<\/a>!&nbsp;<\/p>","protected":false},"excerpt":{"rendered":"<p>\u5927\u9ebb\u306e\u30d0\u30a4\u30aa\u30a2\u30d9\u30a4\u30e9\u30d3\u30ea\u30c6\u30a3\u3068P450\u30c1\u30c8\u30af\u30ed\u30fc\u30e0\u30fb\u30ab\u30f3\u30ca\u30d3\u30ce\u30a4\u30c9\u306e\u4ee3\u8b1d\u306b\u3064\u3044\u3066\u79d1\u5b66\u304c\u4f55\u3092\u8a00\u3063\u3066\u3044\u308b\u304b\u3092\u77e5\u308a\u305f\u3044\u306a\u3089\u3001\u3053\u306e\u8a18\u4e8b\u306f\u3042\u306a\u305f\u306e\u305f\u3081\u306e\u3082\u306e\u3067\u3059\u3002\u5927\u9ebb\u3092\u5229\u7528\u3057\u305f\u533b\u85ac\u54c1\u306b\u95a2\u3057\u3066\u306f\u3001\u305d\u308c\u307b\u3069\u591a\u304f\u306e\u30c7\u30fc\u30bf\u306f\u3042\u308a\u307e\u305b\u3093\u304c\u3001\u7814\u7a76\u306b\u3088\u3063\u3066\u3001\u79d1\u5b66\u8005\u306f\u3059\u3067\u306b\u52b9\u7387\u3001\u5b89\u5168\u6027\u3001\u85ac\u7269\u76f8\u4e92\u4f5c\u7528\u3092\u4e88\u6e2c\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u307e\u305f\u3001\u30ab\u30f3\u30ca\u30d3\u30ce\u30a4\u30c9\u6cbb\u7642\u3084\u30ab\u30f3\u30ca\u30d3\u30ce\u30a4\u30c9\u305d\u306e\u3082\u306e\u306b\u3064\u3044\u3066\u306e\u65ad\u5b9a\u7684\u306a\u7d50\u679c\u306f\u591a\u304f\u306a\u3044\u3082\u306e\u306e\u3001\u751f\u6d3b\u306e\u8cea\u3092\u5411\u4e0a\u3055\u305b\u305f\u60a3\u8005\u306e\u6c7a\u5b9a\u7684\u306a\u80af\u5b9a\u7684\u7d50\u679c\u304c\u7814\u7a76\u306b\u3088\u3063\u3066\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u3002  \u7d4c\u53e3\u6295\u4e0e\u3055\u308c\u305f\u85ac\u306f\u3001\u307e\u305a\u4f53\u5185\u306e\u9175\u7d20\u3067\u4ee3\u8b1d\u3055\u308c\u307e\u3059\u304c\u3001\u3053\u308c\u306f\u85ac\u7269\u6cbb\u7642\u52b9\u679c\u306b\u76f4\u63a5\u5f71\u97ff\u3059\u308b\u91cd\u8981\u306a\u30b9\u30c6\u30c3\u30d7\u3067\u3059\u3002  \u306b\u95a2\u9023\u3059\u308bMind the Graph Gallery\u306e\u30a4\u30e9\u30b9\u30c8\u3092\u30c1\u30a7\u30c3\u30af\u3059\u308b [...]...<\/p>","protected":false},"author":18,"featured_media":13179,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[66,959,958,28],"tags":[51,554],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Cannabis Bioavailability: all you need to know - MTG<\/title>\n<meta name=\"description\" content=\"What happens when cannabis enters the body? 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