{"id":13008,"date":"2021-06-21T18:09:00","date_gmt":"2021-06-21T21:09:00","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=13008"},"modified":"2023-01-05T14:38:06","modified_gmt":"2023-01-05T17:38:06","slug":"napping-time-genetics","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/ja\/%e6%98%bc%e5%af%9d%e3%82%bf%e3%82%a4%e3%83%a0%e3%82%b8%e3%82%a7%e3%83%8d%e3%83%86%e3%82%a3%e3%82%af%e3%82%b9\/","title":{"rendered":"\u4eee\u7720\u6642\u9593\u907a\u4f1d\u5b66\u3002\u663c\u5bdd\u304c\u907a\u4f1d\u7684\u5909\u7570\u306b\u4e0e\u3048\u308b\u5f71\u97ff"},"content":{"rendered":"

\u65e5\u4e2d\u306e\u663c\u5bdd\u30bf\u30a4\u30e0\u306f\u3001\u500b\u4eba\u306e\u7f6a\u306e\u610f\u8b58\u3092\u611f\u3058\u308b\u3053\u3068\u304c\u307b\u3068\u3093\u3069\u3067\u3059\u3002<\/p>\n\n\n

\n
\"\u30ac\u30fc\u30d5\u30a3\u30fc\u30eb\u30c9\u3001\u30d9\u30c3\u30c9\u3067\u663c\u5bdd\"<\/a><\/figure><\/div>\n\n\n

\u307b\u3068\u3093\u3069\u306e\u5834\u5408\u3001\u305d\u308c\u306f\u65e5\u5e38\u751f\u6d3b\u306e\u4e2d\u3067\u67d3\u307f\u4ed8\u3044\u305f\u7fd2\u6163\u3067\u3082\u3042\u308a\u307e\u3059\u3002\u30cf\u30a8\u304b\u3089\u54fa\u4e73\u985e\u307e\u3067\u3001\u591a\u304f\u306e\u7a2e\u3067\u3054\u304f\u666e\u901a\u306b\u898b\u3089\u308c\u308b\u3002<\/p>\n\n\n\n

\u307e\u305f\u3001\u663c\u5bdd\u306f\u899a\u9192\u5ea6\u306e\u5411\u4e0a\u306b\u3082\u3064\u306a\u304c\u308a\u3001\u591c\u9045\u304f\u307e\u3067\u4ed5\u4e8b\u3092\u3059\u308b\u4eba\u3084\u3001\u666e\u6bb5\u304b\u3089\u7761\u7720\u4e0d\u8db3\u306e\u4eba\u306b\u306f\u6b20\u304b\u305b\u306a\u3044\u3002<\/p>\n\n\n\n

\u307e\u305f\u3001\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u3084\u8a18\u61b6\u529b\u306e\u5411\u4e0a\u3001\u30b9\u30c8\u30ec\u30b9\u306e\u7de9\u548c\u306b\u3082\u52b9\u679c\u304c\u3042\u308b\u3068\u8a00\u308f\u308c\u3066\u3044\u307e\u3059\u3002 <\/p>\n\n\n\n

\u3057\u304b\u3057\u3001\u3053\u308c\u3089\u306e\u5229\u70b9\u3068\u306f\u5225\u306b\u3001\u663c\u5bdd\u306e\u9577\u671f\u7684\u306a\u5f71\u97ff\u306f\u3001\u500b\u4eba\u306e\u5e78\u798f\u306b\u5bfe\u3057\u3066\u6162\u6027\u7684\u306a\u3082\u306e\u3067\u3042\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n

\u3053\u306e\u70b9\u306b\u3064\u3044\u3066\u306f\u8cdb\u5426\u4e21\u8ad6\u3042\u308a\u3001\u7761\u7720\u30b5\u30a4\u30af\u30eb\u306e\u4e0d\u5099\u3001\u98df\u751f\u6d3b\u306e\u4e71\u308c\u3001\u4f53\u8abf\u4e0d\u826f\u306a\u3069\u3001\u663c\u5bdd\u306b\u95a2\u9023\u3059\u308b\u8907\u6570\u306e\u8981\u56e0\u304c\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n

\u65e5\u4e2d\u306e\u663c\u5bdd\u306e\u6642\u9593\u306f\u5e78\u305b\u306a\u6642\u9593\u304b\uff1f\u7814\u7a76\u8005\u306f\u305d\u3046\u3067\u306f\u306a\u3044\u3068\u8a00\u3044\u307e\u3059\u3002 <\/strong><\/p>\n\n\n\n

\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u907a\u4f1d\u5b50\u306e\u5909\u7570\u306b\u3088\u308b\u663c\u5bdd\u306e\u52b9\u679c\u3092\u5206\u6790\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

\u5f7c\u3089\u306e\u7814\u7a76\u306f\u3001\u663c\u5bdd\u306e\u6642\u9593\u3084\u55dc\u597d\u3092\u901a\u3057\u3066\u3001\u3055\u307e\u3056\u307e\u306a\u500b\u4eba\u306e\u907a\u4f1d\u7684\u5909\u7570\u3092\u7406\u89e3\u3059\u308b\u3053\u3068\u304b\u3089\u6210\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\u73fe\u5728\u3001\u30b2\u30ce\u30e0\u30ef\u30a4\u30c9\u95a2\u9023\u7814\u7a76\u306b\u3088\u308a\u3001\u65e5\u4e2d\u306e\u663c\u5bdd\u6642\u9593\u306b\u5bfe\u5fdc\u3059\u308b\u907a\u4f1d\u5b50\u5ea7\u304c7\u3064\u307b\u3069\u767a\u898b\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\u82f1\u56fd\u30d0\u30a4\u30aa\u30d0\u30f3\u30af\u306b\u767b\u9332\u3055\u308c\u305f\u30e8\u30fc\u30ed\u30c3\u30d1\u7cfb\u4f4f\u6c11\uff08n=452,633\uff09\u306e\u3046\u3061\u3001\u6642\u3005\u663c\u5bdd\u3092\u3059\u308b\u4eba\u304c\u7d0438.2%\u3001\u3044\u3064\u3082\u663c\u5bdd\u3092\u3057\u3066\u3044\u308b\u4eba\u304c5.3%\u3067\u3057\u305f\u3002<\/p>\n\n\n\n

\u305d\u308c\u3089\u306e\u663c\u5bdd\u306e\u6642\u9593\u306f\u307b\u3068\u3093\u3069\u3001BMI\u3084\u4f53\u683c\u6307\u6570\u304c\u9ad8\u3044\u3001\u7761\u7720\u969c\u5bb3\u3068\u8a3a\u65ad\u3055\u308c\u305f\u3053\u3068\u304c\u3042\u308b\u3001\u55ab\u7159\u8005\u3001\u9000\u8077\u8005\u306a\u3069\u306e\u9ad8\u9f62\u7537\u6027\u3067\u3042\u3063\u305f\u3002\u5f7c\u3089\u306f\u3001\u7d044,000\u4eba\u306e\u53c2\u52a0\u8005\u3092\u5bfe\u8c61\u306b\u3001\u9ad8\u54c1\u8cea\u306a\u5e30\u5c5e\u907a\u4f1d\u5b50\u306e\u5909\u7570\u3092\u7528\u3044\u305f\u30b2\u30ce\u30e0\u30ef\u30a4\u30c9\u95a2\u9023\u7814\u7a76\uff08GWAS\uff09\u3092\u5b9f\u65bd\u3057\u305f\u3002\u3053\u308c\u306f\u3001\u5148\u306b\u767a\u898b\u3055\u308c\u305f\u69d8\u3005\u306a\u56e0\u5b50\u3092\u5909\u5316\u3055\u305b\u308b\u3053\u3068\u3067\u884c\u308f\u308c\u305f\u3002<\/p>\n\n\n\n

\u305d\u306e\u7d50\u679c\u3001123\u306e\u907a\u4f1d\u5b50\u5ea7\u3092\u7279\u5b9a\u3059\u308b\u3053\u3068\u306b\u6210\u529f\u3057\u3001\u4e00\u5869\u57fa\u591a\u578b\u306b\u57fa\u3065\u304f\u907a\u4f1d\u7387\u306f\u7d0411.9%\u3067\u3042\u3063\u305f\u3002<\/p>\n\n\n\n

\u5f7c\u3089\u306f\u3001BMI\u306e\u9ad8\u3044\u4eba\u304b\u3089GWAS\u3092\u7d5e\u308a\u8fbc\u3093\u3067\u3044\u3063\u305f\u3002 <\/p>\n\n\n\n

123\u306e\u907a\u4f1d\u5b50\u5ea7\u306e\u3046\u3061\u3001110\u306e\u907a\u4f1d\u5b50\u5ea7\u304c\u30b2\u30ce\u30e0\u30ef\u30a4\u30c9\u306b\u6709\u610f\u306b\u7559\u307e\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u305f\u3002<\/p>\n\n\n\n

\u307e\u305f\u3001X\u67d3\u8272\u4f53\u306e\u95a2\u9023\u6027\u304b\u3089\u3001\u6027\u5225\u306b\u3088\u308b\u663c\u5bdd\u306e\u30d1\u30bf\u30fc\u30f3\u306e\u9055\u3044\u3082\u5206\u6790\u3057\u305f\u3002 <\/p>\n\n\n\n

\u3055\u3089\u306b\u3001\u80a5\u6e80\u306b\u3088\u308b\u904e\u7720\u7d4c\u8def\u306e\u539f\u56e0\u3068\u306a\u308b\u907a\u4f1d\u5b50\u306b\u3064\u3044\u3066\u3082\u7d50\u8ad6\u3092\u51fa\u3057\u305f\u3002 PNOC\uff08\u30d7\u30ec\u30d7\u30ed\u30ce\u30b7\u30bb\u30d7\u30c1\u30f3\uff09\u3002 <\/em>\u3068 PATJ (crumb cell polarity component)\u3002<\/em><\/p>\n\n\n\n

\u3055\u3089\u306b\u3001\u30b3\u30ed\u30cb\u30fc\u5316\u3057\u305fFADS1\uff08Fatty Acid Desaturase\uff09\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u306f\u3001\u7761\u7720\u30d1\u30bf\u30fc\u30f3\u306b\u5bfe\u3059\u308b\u8102\u8cea\u4ee3\u8b1d\u306epleiotropic\u52b9\u679c\u3092\u63d0\u5531\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\u305d\u306e\u4ed6\u306e\u76f8\u95a2\u306f\u3001\u8840\u7cd6\u5024\u3001\u4f53\u683c\u3001\u4ee3\u8b1d\u306a\u3069\u306e\u5f62\u8cea\u3068\u30b2\u30ce\u30e0\u30ef\u30a4\u30c9\u306a\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2\u3067\u8a8d\u3081\u3089\u308c\u3001\u3053\u306e\u3046\u3061\u591a\u304f\u306e\u76f8\u95a2\u306fBMI\u3092\u8003\u616e\u3059\u308b\u3068\u6e1b\u5c11\u3057\u305f\u3002 <\/p>\n\n\n\n

\u3055\u3089\u306b\u3001\u65e5\u4e2d\u4eee\u7720\u306e\u30b2\u30ce\u30e0\u30ef\u30a4\u30c9\u591a\u907a\u4f1d\u5b50\u3092\u5229\u7528\u3057\u305fphenome-wide association\u3067\u89e3\u6790\u3057\u305f\u30b9\u30b3\u30a2\u306f\u3001\u80a5\u6e80\u3001\u9ad8\u8840\u5727\u3001\u305d\u3057\u3066\u6700\u3082\u91cd\u8981\u306a\u5fc3\u4ee3\u8b1d\u7cfb\u75be\u60a3\u306b\u95a2\u9023\u3059\u308b\u75be\u60a3\u306e\u76f8\u95a2\u306b\u3082\u5bc4\u4e0e\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u307e\u3057\u305f\u3002 <\/p>\n\n\n\n

\u7d50\u8ad6\u304b\u3089\u8a00\u3046\u3068\u3001\u5f7c\u3089\u306e\u767a\u898b\u306f\u76ee\u304b\u3089\u9c57\u3067\u3042\u308b\u3002\u6642\u306b\u306f\u3001\u305d\u306e\u3088\u3046\u306a\u7fd2\u6163\u304c\u3001\u79c1\u305f\u3061\u306e\u4f53\u306b\u3044\u304f\u3064\u3082\u306e\u671b\u307e\u3057\u304f\u306a\u3044\u5408\u4f75\u75c7\u3092\u3082\u305f\u3089\u3059\u3053\u3068\u3082\u3042\u308b\u306e\u3067\u3059\u3002\u5065\u5eb7\u7684\u306a\u65e5\u5e38\u751f\u6d3b\u3068\u826f\u3044\u751f\u6d3b\u7fd2\u6163\u3092\u5b88\u3089\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u3002 <\/p>\n\n\n

\n
\"\u306d\u3076\u304f\u308d\u304c\u305f\u304a\u308c\u308b<\/a><\/figure><\/div>\n\n\n

\u7814\u7a76\u5185\u5bb9\u306b\u3064\u3044\u3066\u306f\u3001\u4e0b\u8a18\u306e\u53c2\u8003\u6587\u732e\u3092\u3054\u89a7\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n\n

Dashti, H.S., Daghlas, I., Lane, J.M. \u3089<\/em> \u65e5\u4e2d\u306e\u4eee\u7720\u306e\u907a\u4f1d\u7684\u6c7a\u5b9a\u56e0\u5b50\u3068\u5fc3\u4ee3\u8b1d\u7cfb\u5065\u5eb7\u3078\u306e\u5f71\u97ff\u3002 \u30ca\u30c3\u30c4\u30fb\u30b3\u30df\u30e5\u30cb\u30b1\u30fc\u30b7\u30e7\u30f3<\/em> 12, 900 (2021).DOI : https:\/\/doi.org\/10.1038\/s41467-020-20585-3<\/a><\/p>\n\n\n\n

Mind the Graph Gallery\u3067\u306f\u3001\u907a\u4f1d\u5b50\u306b\u95a2\u9023\u3059\u308b\u30a4\u30e9\u30b9\u30c8\u3092\u591a\u6570\u63b2\u8f09\u3057\u3066\u3044\u307e\u3059\u3002\u4e0b\u306e\u753b\u50cf\u3092\u30af\u30ea\u30c3\u30af\u3057\u3066\u3054\u78ba\u8a8d\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n

\n
\"\"\/<\/a><\/figure><\/div>","protected":false},"excerpt":{"rendered":"

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Researchers analyzed the effects of napping through genetics variation.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mindthegraph.com\/blog\/ja\/dremez-genetika\/\" \/>\n<meta property=\"og:locale\" content=\"ja_JP\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Napping Time Genetics: How Taking a Nap Can Influence Genetic Variation\" \/>\n<meta property=\"og:description\" content=\"Is napping time your happy hour? 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