{"id":16651,"date":"2022-09-12T18:50:00","date_gmt":"2022-09-12T21:50:00","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/?p=16651"},"modified":"2023-03-17T14:47:35","modified_gmt":"2023-03-17T17:47:35","slug":"success-case-immunotherapeutic-potential-of-crotoxin-anti-inflammatory-and-immunosuppressive-properties","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/it\/successo-caso-immunoterapico-potenziale-della-crotossina-antinfiammatorio-e-immunosoppressivo-proprieta\/","title":{"rendered":"Potenziale immunoterapeutico della crotossina: propriet\u00e0 antinfiammatorie e immunosoppressive Rassegna cartacea"},"content":{"rendered":"<p>Potrebbe essere un po' difficile spiegare la modulazione antinfiammatoria della crotossina senza le immagini appropriate, ma \u00e8 per questo che esiste Mind the Graph!<\/p>\n\n\n\n<h2><strong>Una revisione della ricerca scientifica sulla crotossina, un veleno del serpente a sonagli<\/strong><\/h2>\n\n\n\n<p>In \"Immunotherapeutic potential of Crotoxin\", Marco Sartim et al. (2018) hanno osservato che negli ultimi 80 anni la crotossina \u00e8 diventata una delle tossine isolate dai veleni di serpente pi\u00f9 studiate. <\/p>\n\n\n\n<p>La crotossina \u00e8 il principale componente tossico del veleno del crotalo sudamericano Crotalus durissus terrificus. Gli studi hanno dimostrato che l'effetto immunomodulatore della C.d.t. \u00e8 associato alla produzione di mediatori antinfiammatori. <\/p>\n\n\n\n<p>La capacit\u00e0 della crotossina e delle sue subunit\u00e0 di modulare il sistema immunitario ha introdotto nuove prospettive come potenziali agenti terapeutici.<\/p>\n\n\n\n<p><strong>I ricercatori hanno esaminato 161 articoli.<\/strong><\/p>\n\n\n\n<p>Controllare il <a href=\"https:\/\/jvat.biomedcentral.com\/articles\/10.1186\/s40409-018-0178-3\" target=\"_blank\" rel=\"noreferrer noopener\">articolo originale qui<\/a>.<\/p>\n\n\n\n<h2><strong>Estratti grafici basati su Mind the Graph<\/strong><\/h2>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html.webp\"><img decoding=\"async\" loading=\"lazy\" width=\"1024\" height=\"1003\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-1024x1003.webp\" alt=\"\" class=\"wp-image-20251\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-1024x1003.webp 1024w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-300x294.webp 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-768x752.webp 768w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-12x12.webp 12w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html-100x98.webp 100w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_fig2_html.webp 1418w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><figcaption class=\"wp-element-caption\"><em>Realizzato con <a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>L'autore ha utilizzato la piattaforma Mind the Graph per creare una figura schematica sulla circolazione, gli eventi tissutali e cellulari modulati dalla Crotossina e dalle sue subunit\u00e0 durante lo stimolo infiammatorio.<\/p>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_Fig3_HTML.webp\"><img decoding=\"async\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/40409_2018_178_Fig3_HTML-839x1024.webp\" alt=\"\" class=\"wp-image-20252\"\/><\/a><figcaption class=\"wp-element-caption\"><em>Realizzato con <a href=\"https:\/\/mindthegraph.com\/app\/graphical-abstract-maker\" target=\"_blank\" rel=\"noreferrer noopener\">Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>L'autore ha inoltre descritto in dettaglio la circolazione sanguigna, l'homing linfonodale dei linfociti e gli eventi cellulari associati agli effetti immunosoppressivi della crotossina e delle sue subunit\u00e0.<\/p>\n\n\n\n<p><strong>Questo \u00e8 il potere delle infografiche!<\/strong><\/p>\n\n\n\n<p>Le conclusioni degli autori sembrano consolidare i lavori precedenti in quest'area: \"La crotossina \u00e8 stata in grado di sopprimere la produzione di anticorpi specifici anti-HSA IgG1 e IgG2a da topi immunizzati con HAS, indicando la sua capacit\u00e0 di modulare le risposte Th1 e Th2\", ha affermato Sartim.<\/p>\n\n\n\n<h2><strong>Impatto e prestazioni dei documenti<\/strong><\/h2>\n\n\n\n<p>Possiamo analizzare con <a href=\"https:\/\/mindthegraph.com\/blog\/altmetric\/\" target=\"_blank\" rel=\"noreferrer noopener\">Altmetric<\/a> dati che questo articolo ha avuto pi\u00f9 citazioni <strong>di <strong>84%<\/strong><\/strong> <strong>di altri articoli di Springer Nature.<\/strong><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><a href=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1.png\"><img decoding=\"async\" loading=\"lazy\" width=\"322\" height=\"578\" src=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1.png\" alt=\"\" class=\"wp-image-20254\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1.png 322w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1-167x300.png 167w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1-7x12.png 7w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/immunotherapeutic-1-56x100.png 56w\" sizes=\"(max-width: 322px) 100vw, 322px\" \/><\/a><figcaption class=\"wp-element-caption\"><em>Fonte <a href=\"https:\/\/citations.springernature.com\/item?doi=10.1186\/s40409-018-0178-3&amp;start=11&amp;years=&amp;journals=&amp;books=&amp;authors=\" target=\"_blank\" rel=\"noreferrer noopener\">Croce<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n<p>Sfruttate la potenza delle infografiche per aumentare e <a href=\"https:\/\/mindthegraph.com\/blog\/research-journal-impact-factor\/\">impatto del vostro articolo<\/a> anche. Provate Mind the Graph!<\/p>\n\n\n\n<div class=\"is-layout-flex wp-block-buttons\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-background wp-element-button\" href=\"https:\/\/mindthegraph.com\/app\/auth\/register?from_url=\/\" style=\"border-radius:100px;background-color:#dc1866\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Prova Mind the Graph<\/strong><\/a><\/div>\n<\/div>\n\n\n\n<div style=\"height:46px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Potrebbe essere un po' difficile spiegare la modulazione antinfiammatoria della crotossina senza le immagini appropriate, ma Mind the Graph esiste!<\/p>","protected":false},"author":29,"featured_media":20047,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[195,958,957,960,1],"tags":[96,554,963],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Immunotherapeutic potential of Crotoxin: anti-inflammatory and immunosuppressive properties Paper Review - 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