{"id":16630,"date":"2022-09-08T18:14:00","date_gmt":"2022-09-08T21:14:00","guid":{"rendered":"https:\/\/mindthegraph.com\/blog\/success-case-zika-virus-replicates-in-adult-human-brain-tissue-and-impairs-synapses-and-memory-in-mice-copy\/"},"modified":"2023-03-17T14:47:54","modified_gmt":"2023-03-17T17:47:54","slug":"success-case-igh-resolution-synchrotron-based-x-ray-microtomography-as-a-tool-to-unveil-the-three-dimensional-neuronal-architecture-of-the-brain","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/id\/kasus-kesuksesan-mikrotomografi-sinar-x-berbasis-sinkrotron-beresolusi-tinggi-sebagai-alat-untuk-mengungkap-arsitektur-neuron-otak-tiga-dimensi\/","title":{"rendered":"Mikrotomografi sinar-X berbasis sinkrotron resolusi tinggi sebagai alat untuk mengungkap arsitektur neuron tiga dimensi otak"},"content":{"rendered":"

Mikrotomografi sinar-X telah muncul sebagai metode baru untuk menguraikan cytoarsitektur dan konektivitas otak, dan di sini kami menyajikan metode untuk mencitrakan seluruh neuron.<\/p>\n\n\n\n

Mikrotomografi sinar-X berbasis sinkrotron resolusi tinggi sebagai alat untuk menyingkap arsitektur neuron tiga dimensi otak<\/strong><\/h2>\n\n\n\n

Dalam 'Mikrotomografi sinar-X berbasis sinkrotron resolusi tinggi sebagai alat untuk mengungkap arsitektur neuron tiga dimensi otak', Matheus de Castro Fonseca dkk. (2018) mencatat bahwa studi tentang neuron sebagai kesatuan yang terindividualisasi dimulai pada abad ke-19 dengan diciptakannya Doktrin Neuron. <\/p>\n\n\n\n

Dalam beberapa tahun terakhir, upaya besar telah dilakukan untuk memahami organisasi neuron dan konektivitas dalam sampel otak yang utuh. Teknik pelabelan Golgi-Cox menawarkan kontras yang sesuai untuk pelabelan spesifik neuron untuk mikrotomografi sinar-X. <\/p>\n\n\n\n

Neuron memiliki morfologi yang berbeda dan pola konektivitas yang spesifik, yang sangat penting untuk fungsi yang tepat. Para peneliti menyajikan metode pencitraan yang menggabungkan mikrotomografi sinar-X berbasis sinkrotron dengan protokol impregnasi Golgi-Cox. <\/p>\n\n\n\n

Metode ini menawarkan kontras yang lebih tinggi dan lebih homogen dari seluruh neuron yang relatif jarang terdistribusi di dalam jaringan.<\/p>\n\n\n\n

Otak diinkubasi dalam larutan pewarnaan Golgi-Cox selama 14 hari, terlindung dari cahaya. Setelah masa inkubasi, otak dibedah secara serial menggunakan vibratome.<\/strong><\/p>\n\n\n\n

Periksa bagian artikel asli di sini<\/a>.<\/p>\n\n\n\n

Abstrak Grafis yang didukung oleh Mind the Graph<\/strong><\/h2>\n\n\n\n
<\/div>\n\n\n
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Dibuat dengan Mind the Graph<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n

Penulis menggunakan Mind the Graph<\/a> untuk membuat ilustrasi skematik yang mewakili tikus dewasa yang disuntik secara i.p. dengan larutan saline atau pilocarpine (280 mg\/kg). Merepresentasikan proses yang kompleks dengan infografis adalah cara yang baik untuk membuatnya mudah dimengerti, tanpa mengesampingkan detail dan informasi penting.<\/p>\n\n\n\n

Beberapa hasil penelitian tampaknya mengkonsolidasikan apa yang sebelumnya telah diketahui tentang area ini: \"Impregnasi neuron berbasis merkuri yang ditunjukkan di sini, memungkinkan kami untuk mendefinisikan dengan jelas seluruh neuron terutama karena impregnasi sel yang lebih kontinu dan homogen serta kepadatan artefak yang jauh lebih rendah,\" de Castro Fonseca menyarankan.<\/p>\n\n\n\n

Dampak dan Kinerja Makalah<\/strong><\/h2>\n\n\n\n

Kita dapat menganalisis dengan Altmetric<\/a> data bahwa skor perhatian online makalah ini lebih tinggi daripada 64%<\/strong><\/strong> dari semua artikel lain yang memiliki usia yang sama di Scientific Reports.<\/strong><\/p>\n\n\n\n

<\/div>\n\n\n
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Sumber Altmetrics<\/a><\/em><\/figcaption><\/figure><\/div>\n\n\n

Tingkatkan aksesibilitas artikel Anda dengan kekuatan infografis.<\/p>\n\n\n\n

\n
Coba Mind the Graph<\/strong><\/a><\/div>\n<\/div>\n\n\n\n
<\/div>","protected":false},"excerpt":{"rendered":"

Lihatlah metode baru untuk menguraikan cytoarsitektur dan konektivitas otak yang diwakili dengan ilustrasi Mind the Graph.<\/p>","protected":false},"author":29,"featured_media":20013,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[195,958,957,960,1],"tags":[96,554,775,963],"yoast_head":"\nHigh-resolution synchrotron-based X-ray microtomography as a tool to unveil the three-dimensional neuronal architecture of the brain Paper Review - Mind the Graph Blog<\/title>\n<meta name=\"description\" content=\"Look into the new method for deciphering the cytoarchitecture and connectivity of the brain represented with Mind the Graph's illustrations.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mindthegraph.com\/blog\/id\/kasus-kesuksesan-mikrotomografi-sinar-x-berbasis-sinkrotron-beresolusi-tinggi-sebagai-alat-untuk-mengungkap-arsitektur-neuron-otak-tiga-dimensi\/\" \/>\n<meta property=\"og:locale\" content=\"id_ID\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"High-resolution synchrotron-based X-ray microtomography as a tool to unveil the three-dimensional neuronal architecture of the brain Paper Review - Mind the Graph Blog\" \/>\n<meta property=\"og:description\" content=\"Look into the new method for deciphering the cytoarchitecture and connectivity of the brain represented with Mind the Graph's illustrations.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/mindthegraph.com\/blog\/id\/kasus-kesuksesan-mikrotomografi-sinar-x-berbasis-sinkrotron-beresolusi-tinggi-sebagai-alat-untuk-mengungkap-arsitektur-neuron-otak-tiga-dimensi\/\" \/>\n<meta property=\"og:site_name\" content=\"Mind the Graph Blog\" \/>\n<meta property=\"article:published_time\" content=\"2022-09-08T21:14:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-03-17T17:47:54+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/blog_2.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1125\" \/>\n\t<meta property=\"og:image:height\" content=\"614\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Artur Zignani\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:image\" content=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2022\/09\/blog_2.jpg\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Artur Zignani\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"High-resolution synchrotron-based X-ray microtomography as a tool to unveil the three-dimensional neuronal architecture of the brain Paper Review - 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