{"id":9012,"date":"2019-06-03T11:07:17","date_gmt":"2019-06-03T14:07:17","guid":{"rendered":"https:\/\/blog.mindthegraph.com\/?p=9012"},"modified":"2022-10-18T08:23:58","modified_gmt":"2022-10-18T11:23:58","slug":"award-zika-virus-infection","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/hu\/award-zika-virus-fertozes\/","title":{"rendered":"Zika-v\u00edrus: A d\u00edjazott tanulm\u00e1ny, amely \u00faj f\u00e9nyt vet a hossz\u00fa t\u00e1v\u00fa k\u00f6vetkezm\u00e9nyekre"},"content":{"rendered":"

Mindig leny\u0171g\u00f6z\u0151, hogy bemutathatjuk felhaszn\u00e1l\u00f3ink tudom\u00e1nyos munk\u00e1j\u00e1t. Ma teh\u00e1t Isis de Souza brazil tud\u00f3sn\u0151t \u00e9s a zikav\u00edrussal kapcsolatos munk\u00e1j\u00e1t mutatom be. Isis \u00e9s koll\u00e9g\u00e1i a korai \u00e9letkorban t\u00f6rt\u00e9n\u0151 zikav\u00edrus-fert\u0151z\u00e9s hat\u00e1s\u00e1t tanulm\u00e1nyozz\u00e1k egerekben. \u0150 is a Mind the Graph felhaszn\u00e1l\u00f3ja, \u00e9s a gy\u0151ztes prezent\u00e1ci\u00f3ban a Mind the Graph vizu\u00e1lis er\u0151forr\u00e1sait haszn\u00e1lja. Nem is lehetn\u00e9nk b\u00fcszk\u00e9bbek.<\/p>\n

Mi a zikav\u00edrus?<\/strong><\/h3>\n

A Zika-v\u00edrus a Flaviviridae csal\u00e1dba tartozik. Ebbe a csoportba sz\u00e1mos patog\u00e9n v\u00edrus tartozik. A legismertebb a s\u00e1rgal\u00e1zv\u00edrus, amely a csal\u00e1d t\u00edpusv\u00edrusa, \u00e9s amelyb\u0151l a csal\u00e1d neve is ered, mivel a flavus sz\u00f3 latinul \"s\u00e1rg\u00e1t\" jelent. Ezen k\u00edv\u00fcl m\u00e1s flaviv\u00edrusok k\u00f6z\u00e9 tartozik m\u00e9g a nyugat-n\u00edlusi v\u00edrus, a dengue-v\u00edrus \u00e9s a kullancsencephalitis v\u00edrus.<\/p>\n

A Flaviviridae csal\u00e1d k\u00f6z\u00f6s m\u00e9ret\u0171 (40-65 nm), \u00e9s a v\u00edrusburkot v\u00e9d\u0151 ikoza\u00e9deres nukleokapszidjuk bor\u00edtja. Emellett a genetikai anyaguk RNS, \u00e9s az elektronmikroszk\u00f3pban megjelennek.<\/p>\n

Az al\u00e1bbi infografika a zikav\u00edrus alapvet\u0151 fel\u00e9p\u00edt\u00e9s\u00e9t mutatja be:<\/p>\n

\"preview_90481\"<\/a><\/p>\n

 A Zika els\u0151sorban a n\u0151i Stegomya aegypti<\/em> sz\u00fanyog, amely a v\u00e9rb\u0151l t\u00e1pl\u00e1lkozik a pet\u00e9k lerak\u00e1s\u00e1hoz. A sz\u00fanyog f\u0151leg nappal akt\u00edv.<\/p>\n

A gy\u0151ztes pap\u00edr<\/strong><\/h2>\n

Az ut\u00f3bbi id\u0151ben sz\u00e1mos kutat\u00f3 tanulm\u00e1nyozza a zikav\u00edrusnak (ZIKV) val\u00f3 velesz\u00fcletett kitetts\u00e9ggel kapcsolatos neurol\u00f3giai rendelleness\u00e9geket.<\/p>\n

Ezenk\u00edv\u00fcl a velesz\u00fcletett mikrokef\u00e1lia az egyik legmark\u00e1nsabb hat\u00e1s, amelyr\u0151l a ZIKV-fert\u0151z\u00f6tt \u00fajsz\u00fcl\u00f6ttekn\u00e9l sz\u00e1moltak be. Emiatt a kutat\u00e1si er\u0151fesz\u00edt\u00e9sek a ZIKV okozta velesz\u00fcletett mikrokef\u00e1lia mechanizmusainak meg\u00e9rt\u00e9s\u00e9re \u00f6sszpontos\u00edtanak.<\/p>\n

Az expoz\u00edci\u00f3nak kitett magzatoknak azonban csak 1-13% eset\u00e9ben fordulnak el\u0151 testi rendelleness\u00e9gek a sz\u00fclet\u00e9skor. Emellett hi\u00e1nyoznak az inform\u00e1ci\u00f3k a perinat\u00e1lis fert\u0151z\u00e9s hossz\u00fa t\u00e1v\u00fa k\u00f6vetkezm\u00e9nyeir\u0151l.<\/p>\n

Isis de Souza \u00e9s munkat\u00e1rsai teh\u00e1t egerek seg\u00edts\u00e9g\u00e9vel tanulm\u00e1nyozt\u00e1k a viselked\u00e9si \u00e9s neuropathol\u00f3giai \u00e1llapotokat, valamint a r\u00f6vid \u00e9s hossz\u00fa t\u00e1v\u00fa k\u00f6vetkezm\u00e9nyeket, \u00e9s az eredm\u00e9nyeket egy tanulm\u00e1nyban tett\u00e9k k\u00f6zz\u00e9, amelynek c\u00edme A korai \u00e9letkori Zika-v\u00edrusfert\u0151z\u00e9s akut \u00e9s kr\u00f3nikus neurol\u00f3giai k\u00f6vetkezm\u00e9nyei egerekben.<\/strong><\/p>\n

Emberekn\u00e9l a zikav\u00edrusnak val\u00f3 kitetts\u00e9ghez sz\u00e1mos klinikai \u00e1llapot t\u00e1rsul, amelyek h\u00f3napokkal vagy \u00e9vekkel a sz\u00fclet\u00e9s ut\u00e1n jelentkeznek. Teh\u00e1t m\u00e9g ha a csecsem\u0151k nem is sz\u00fcletnek mikrokef\u00e1li\u00e1val, akkor is jelentkezhetnek mozg\u00e1sszervi k\u00e1rosod\u00e1sok, g\u00f6rcsrohamokkal j\u00e1r\u00f3 agyk\u00e9rgi diszpl\u00e1zia \u00e9s m\u00e1s neurol\u00f3giai rendelleness\u00e9gek.<\/p>\n

A szerz\u0151k szerint \"\u00fajsz\u00fcl\u00f6tt vad t\u00edpus\u00fa egereket fert\u0151ztek sziszt\u00e9m\u00e1san ZIKV-vel, \u00e9s a fert\u0151z\u00e9s viselked\u00e9si, neuropatol\u00f3giai \u00e9s molekul\u00e1ris k\u00f6vetkezm\u00e9nyeinek hossz\u00fa t\u00e1v\u00fa nyomon k\u00f6vet\u00e9s\u00e9t v\u00e9gezt\u00e9k el. R\u00f6vid \u00e9s hossz\u00fa t\u00e1v\u00fa sz\u00f6v\u0151dm\u00e9nyekr\u0151l sz\u00e1molunk be a ZIKV-fert\u0151z\u00e9st k\u00f6vet\u0151en egerekben, \u00e9s megmutatjuk, hogy a korai tumor nekr\u00f3zis faktor-\u03b1 (TNF-\u03b1) semleges\u00edt\u00e9s r\u00e9szben megakad\u00e1lyozza ezeket a k\u00e1ros hat\u00e1sokat. Eredm\u00e9nyeink r\u00e1vil\u00e1g\u00edtanak arra, hogy a ZIKV-vel val\u00f3 velesz\u00fcletett expoz\u00edci\u00f3t k\u00f6vet\u0151en k\u00fcl\u00f6n\u00f6s figyelmet kell ford\u00edtani a neuropatol\u00f3giai sz\u00f6v\u0151dm\u00e9nyek lehets\u00e9ges terh\u00e9re a gyermekek \u00e9s serd\u00fcl\u0151k k\u00f6r\u00e9ben, \u00e9s azt sugallj\u00e1k, hogy a neuroinflamm\u00e1ci\u00f3 korai g\u00e1tl\u00e1sa lehets\u00e9ges kezel\u00e9s lehet a hossz\u00fa t\u00e1v\u00fa neurol\u00f3giai k\u00f6vetkezm\u00e9nyek megel\u0151z\u00e9s\u00e9re a ZIKV-fert\u0151z\u00f6tt csecsem\u0151kn\u00e9l.\"\"<\/em><\/p>\n

 A GE Healthcare Life Sciences \u00e1ltal t\u00e1mogatott d\u00edj<\/strong><\/h2>\n

A \"Pr\u00eamio Jovem Talento em Ci\u00eancias da Vida\", azaz az \u00e9lettudom\u00e1nyok fiatal tehets\u00e9gei d\u00edjat a Brazil Biok\u00e9miai \u00e9s Molekul\u00e1ris Biol\u00f3giai T\u00e1rsas\u00e1g \u00e9s a GE Healthcare Life Sciences t\u00e1mogatja. Egy tudom\u00e1nyos bizotts\u00e1g \u00f6t jel\u00f6ltet v\u00e1lasztott ki, akik bemutathatj\u00e1k munk\u00e1jukat az \u00e9ves kongresszuson, amely Latin-Amerika minden r\u00e9sz\u00e9b\u0151l \u00e9rkez\u0151 professzorokat \u00e9s di\u00e1kokat \u00f6sszek\u00f6t\u0151 esem\u00e9ny.<\/p>\n

A bizotts\u00e1g Isis de Oliveira-t v\u00e1lasztotta ki, aki a zikav\u00edrusnak val\u00f3 kitetts\u00e9g k\u00f6vetkezm\u00e9nyeir\u0151l sz\u00f3l\u00f3 tanulm\u00e1ny\u00e1t mutatta be.<\/p>\n

\"tudom\u00e1nyos
Isis de Oliveira bemutatja eredm\u00e9nyeit<\/figcaption><\/figure>\n

Egy posztban k\u00f6sz\u00f6netet mondott az egyetem\u00e9nek \u00e9s az \u00f6szt\u00f6nd\u00edjnak, amely lehet\u0151v\u00e9 tette a tanulm\u00e1nyait. Tov\u00e1bb\u00e1 rem\u00e9ny\u00e9t fejezte ki, hogy a j\u00f6v\u0151 gener\u00e1ci\u00f3j\u00e1nak lehet\u0151s\u00e9gei ny\u00edlnak arra, hogy tudom\u00e1nyos karriert tudjon befutni, mint \u0151 maga.<\/p>\n

Ez\u00e9rt szeretn\u00e9nk gratul\u00e1lni Isisnek a csod\u00e1latos munk\u00e1j\u00e1hoz! Rem\u00e9lem, munk\u00e1j\u00e1val m\u00e9g t\u00f6bb embert inspir\u00e1l arra, hogy tud\u00f3s legyen.<\/p>\n

Ha pedig vizu\u00e1lisabb\u00e1 szeretn\u00e9 tenni az adatait, hogy jobban kommunik\u00e1lhasson a tudom\u00e1nyban, pr\u00f3b\u00e1lja ki az Mind the Graph-t:<\/p>\n

\"a<\/a><\/p>","protected":false},"excerpt":{"rendered":"

Mindig leny\u0171g\u00f6z\u0151, hogy bemutathatjuk felhaszn\u00e1l\u00f3ink tudom\u00e1nyos munk\u00e1j\u00e1t. Ma teh\u00e1t Isis de Souza brazil tud\u00f3sn\u0151t \u00e9s a zikav\u00edrussal kapcsolatos munk\u00e1j\u00e1t mutatom be. Isis \u00e9s koll\u00e9g\u00e1i a korai \u00e9letkorban t\u00f6rt\u00e9n\u0151 zikav\u00edrus-fert\u0151z\u00e9s hat\u00e1s\u00e1t tanulm\u00e1nyozz\u00e1k egerekben. \u0150 is a mind the graph felhaszn\u00e1l\u00f3ja, \u00e9s a gy\u0151ztes prezent\u00e1ci\u00f3 [...]<\/p>","protected":false},"author":11,"featured_media":9080,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"image","meta":[],"categories":[40],"tags":[299,282,554,71,775,293,316,315],"yoast_head":"\nZika virus: the award-winning study that sheds light on the future<\/title>\n<meta name=\"description\" content=\"Microcephaly is a known effect related to congenital exposure to zika virus. But there is a lack of information of long-term consequences of the infection.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mindthegraph.com\/blog\/hu\/award-zika-virus-fertozes\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Zika virus: the award-winning study that sheds light on the future\" \/>\n<meta property=\"og:description\" content=\"Microcephaly is a known effect related to congenital exposure to zika virus. 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