{"id":7254,"date":"2017-06-21T17:35:04","date_gmt":"2017-06-21T20:35:04","guid":{"rendered":"https:\/\/blog.mindthegraph.com\/?p=7254"},"modified":"2022-10-18T08:29:23","modified_gmt":"2022-10-18T11:29:23","slug":"alzheimers-graphical-abstracts","status":"publish","type":"post","link":"https:\/\/mindthegraph.com\/blog\/hu\/alzheimers-graphical-abstracts\/","title":{"rendered":"Alzheimer-k\u00f3r grafikus kivonatai: Az idegtudom\u00e1nyok \u00fajdons\u00e1gai vizu\u00e1lis form\u00e1ban"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Nagyon szeretj\u00fck bemutatni felhaszn\u00e1l\u00f3ink hihetetlen munk\u00e1j\u00e1t - k\u00fcl\u00f6n\u00f6sen, ha az Mind the Graph illusztr\u00e1ci\u00f3it \u00e9s eszk\u00f6zeit haszn\u00e1lva publik\u00e1lnak.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Teh\u00e1t ma megmutatjuk neked a pr\u00e9mium felhaszn\u00e1l\u00f3 kutat\u00e1s\u00e1t a grafikon elm\u00e9j\u00e9ben, <a href=\"https:\/\/www.researchgate.net\/profile\/Stefania_Forner3\">Stefania Forner<\/a>.  A k\u00f6zelm\u00faltban jelent meg \u00e1ttekint\u0151 cikke a Trends in Neurosciences c\u00edm\u0171 foly\u00f3iratban.<\/span><b><a href=\"http:\/\/www.cell.com\/trends\/neurosciences\/fulltext\/S0166-2236(17)30069-3?rss=yes\"> Szinaptikus k\u00e1rosod\u00e1s az Alzheimer-k\u00f3rban: A diszregul\u00e1lt szimf\u00f3nia.<\/a> <\/b>\u00a0K\u00e9t Alzheimer-grafikus absztraktot k\u00e9sz\u00edtett munk\u00e1ja illusztr\u00e1l\u00e1s\u00e1ra.<\/p>\n<p style=\"text-align: justify;\"><span style=\"font-weight: 400;\"><strong>El\u0151sz\u00f6r is, kezdj\u00fck egy kis bemutatkoz\u00e1ssal Stef\u00e1nia tanulm\u00e1nyi ter\u00fcletr\u0151l<\/strong>:<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Az Alzheimer-k\u00f3r (Alzheimer-k\u00f3r) olyan neurodegenerat\u00edv betegs\u00e9g, amely kognit\u00edv hi\u00e1nyoss\u00e1gokat \u00e9s mem\u00f3riaveszt\u00e9st okoz.  Az Alzheimer-k\u00f3r a hatodik vezet\u0151 hal\u00e1loz\u00e1si ok az Egyes\u00fclt \u00c1llamokban, \u00e9s a k\u00f6vetkez\u0151ket \u00e9rinti <strong>35 milli\u00f3 ember<\/strong> a vil\u00e1g minden t\u00e1j\u00e1n. <\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-weight: 400;\">Bizony\u00edt\u00e9kok utalnak arra, hogy az Alzheimer-k\u00f3r kognit\u00edv deficitjei \u00e9s a szinapszisok elveszt\u00e9se k\u00f6z\u00f6tt ok-okozati \u00f6sszef\u00fcgg\u00e9s van. A szinapszisok diszfunkci\u00f3ja k\u00e9t k\u00f3ros \u00fatvonallal is \u00f6sszef\u00fcgghet. A sejteken k\u00edv\u00fcli felhalmoz\u00f3d\u00e1s <strong>b\u00e9ta-amiloid peptid<\/strong> \u00e9s az intracellul\u00e1ris felhalmoz\u00f3d\u00e1sa <strong>tau feh\u00e9rje<\/strong>.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-weight: 400;\">Ez a k\u00e9t folyamat k\u00f6ztudottan fontos szerepet j\u00e1tszik az Alzheimer-k\u00f3rban. Az egyik legfontosabb alapvet\u0151 k\u00e9rd\u00e9s azonban tov\u00e1bbra is a b\u00e9ta-amiloid \u00e9s a tau k\u00f6z\u00f6tti molekul\u00e1ris kapcsolatra vonatkozik, \u00e9s arra, hogy ez a k\u00e9t szerepl\u0151 hogyan okozza egym\u00e1st\u00f3l k\u00f6lcs\u00f6n\u00f6sen f\u00fcgg\u0151 m\u00f3don a szinaptikus funkci\u00f3k k\u00e1rosod\u00e1s\u00e1t az Alzheimer-k\u00f3rban.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-weight: 400;\">Stefania teh\u00e1t a tau feh\u00e9rje \u00e9s a b\u00e9ta-amiloid peptid szinaptikus funkci\u00f3ra \u00e9s az Alzheimer-k\u00f3rra gyakorolt hat\u00e1s\u00e1nak k\u00fcl\u00f6n-k\u00fcl\u00f6n t\u00f6rt\u00e9n\u0151 elemz\u00e9s\u00e9hez k\u00e9t grafikus kivonatot haszn\u00e1lt, amelyeket az Mind the Graph platformon k\u00e9sz\u00edtett. Az egyik a b\u00e9ta-amiloid oligomerek kialakul\u00e1s\u00e1t \u00e9s a szinaptikus toxicit\u00e1s mechanizmusait, a m\u00e1sik pedig a tau-feh\u00e9rje \u00e9s a neuronok szinapszisai k\u00f6z\u00f6tti kapcsolatot mutatja be. \u00a0<\/span><\/p>\n<h2 style=\"text-align: justify;\"><strong>Alzheimer-k\u00f3r grafikus kivonatai<\/strong><\/h2>\n<p><a href=\"https:\/\/blog.mindthegraph.com\/wp-content\/uploads\/2017\/06\/alzheimer-disorder.png\"><img decoding=\"async\" loading=\"lazy\" class=\"aligncenter wp-image-7255\" src=\"https:\/\/blog.mindthegraph.com\/wp-content\/uploads\/2017\/06\/alzheimer-disorder.png\" alt=\"Alzheimer-k\u00f3r\" width=\"580\" height=\"473\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2017\/06\/alzheimer-disorder.png 521w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2017\/06\/alzheimer-disorder-300x245.png 300w\" sizes=\"(max-width: 580px) 100vw, 580px\" \/><\/a><\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/blog.mindthegraph.com\/wp-content\/uploads\/2017\/06\/alzheimer-disorder-tau.png\"><img decoding=\"async\" loading=\"lazy\" class=\"aligncenter size-full wp-image-7256\" src=\"https:\/\/blog.mindthegraph.com\/wp-content\/uploads\/2017\/06\/alzheimer-disorder-tau.png\" alt=\"alzheimer-rendelleness\u00e9g-tau\" width=\"607\" height=\"609\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2017\/06\/alzheimer-disorder-tau.png 607w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2017\/06\/alzheimer-disorder-tau-150x150.png 150w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2017\/06\/alzheimer-disorder-tau-300x300.png 300w\" sizes=\"(max-width: 607px) 100vw, 607px\" \/><\/a><\/p>\n<p>&nbsp;<\/p>\n<blockquote>\n<p style=\"text-align: right;\">\"K\u00fcl\u00f6n\u00f6sen az A\u00df, a tau \u00e9s a szinaptikus hi\u00e1nyoss\u00e1gok \u00e9s\/vagy vesztes\u00e9gek k\u00f6z\u00f6tti molekul\u00e1ris kapcsolatot vizsg\u00e1l\u00f3 tanulm\u00e1nyok vil\u00e1g\u00edtottak r\u00e1 arra, hogy ezek a patol\u00f3gi\u00e1k v\u00e9g\u00fcl hogyan vezethetnek a betegek kognit\u00edv hanyatl\u00e1s\u00e1hoz. Sz\u00e1mos potenci\u00e1lis pre- \u00e9s posztszinaptikus \u00fatvonal azonos\u00edt\u00e1sa hozz\u00e1j\u00e1rulhat az Alzheimer-k\u00f3r klinikai t\u00fcneteinek h\u00e1tter\u00e9ben \u00e1ll\u00f3 t\u00fcnetekhez\".\"<\/p>\n<\/blockquote>\n<h2><\/h2>\n<p>&nbsp;<\/p>\n<h2><b>\u00c9n is szeretn\u00e9k grafikus \u00f6sszefoglal\u00f3kat a kutat\u00e1saimhoz!<\/b><\/h2>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">A grafikai \u00f6sszefoglal\u00f3kkal kieg\u00e9sz\u00edtheti \u00e9s illusztr\u00e1lhatja munk\u00e1ja f\u0151 pontjait. Ha szeretn\u00e9d megtanulni, hogyan k\u00e9sz\u00edtsd el a saj\u00e1t csod\u00e1latos grafikai absztraktjaidat, itt van n\u00e9h\u00e1ny bejegyz\u00e9s, amely seg\u00edthet neked:<\/span><\/p>\n<ul>\n<li><a href=\"https:\/\/blog.mindthegraph.com\/graphical-abstracts-3-steps\/#.WUrD72grIdU\" target=\"_blank\" rel=\"noopener\">Grafikus \u00f6sszefoglal\u00f3k: 3 l\u00e9p\u00e9snyire vagy<\/a><\/li>\n<li><a href=\"https:\/\/blog.mindthegraph.com\/improvements\/#.WUrD9mgrIdU\" target=\"_blank\" rel=\"noopener\">Szeretj\u00fck a friss\u00edt\u00e9seket: A mindennapos fejleszt\u00e9s<\/a><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">Az Mind the Graph haszn\u00e1lat\u00e1t ingyenesen kezdheti el. Van egy ingyenes v\u00e1ltozatunk, amelyben kipr\u00f3b\u00e1lhatja \u00e9s hozz\u00e1f\u00e9rhet tudom\u00e1nyos k\u00f6nyvt\u00e1runkhoz. A pr\u00e9mium felhaszn\u00e1l\u00f3k teljes hozz\u00e1f\u00e9r\u00e9st kapnak a platformhoz \u00e9s k\u00fcl\u00f6nleges el\u0151ny\u00f6kkel rendelkeznek, amint azt itt l\u00e1thatja.<\/span><\/p>\n<p><a href=\"https:\/\/blog.mindthegraph.com\/wp-content\/uploads\/2016\/10\/start_now.png\"><img decoding=\"async\" loading=\"lazy\" class=\"aligncenter wp-image-6373\" src=\"https:\/\/blog.mindthegraph.com\/wp-content\/uploads\/2016\/10\/start_now.png\" alt=\"infografika63724-3\" width=\"500\" height=\"200\" srcset=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2016\/10\/start_now.png 1500w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2016\/10\/start_now-300x120.png 300w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2016\/10\/start_now-768x307.png 768w, https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2016\/10\/start_now-1024x410.png 1024w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/><\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>Nagyon szeretj\u00fck bemutatni felhaszn\u00e1l\u00f3ink hihetetlen munk\u00e1j\u00e1t - k\u00fcl\u00f6n\u00f6sen, ha az Mind the Graph illusztr\u00e1ci\u00f3it \u00e9s eszk\u00f6zeit haszn\u00e1lva publik\u00e1lnak. Ez\u00e9rt ma megmutatjuk nektek a mind the graph egyik pr\u00e9mium felhaszn\u00e1l\u00f3j\u00e1nak, Stefania Fornernek a kutat\u00e1s\u00e1t.  \u00c1ttekint\u0151 cikke nemr\u00e9giben jelent meg a Trends in Neurosciences c\u00edm\u0171 szaklapban Szinaptikus k\u00e1rosod\u00e1s az Alzheimer-k\u00f3rban [...]<\/p>","protected":false},"author":11,"featured_media":7269,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[956],"tags":[214,213,96,554,216,775,215],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Alzheimer&#039;s graphical abstracts: What&#039;s new in neuroscience in a visual way - Mind the Graph Blog<\/title>\n<meta name=\"description\" content=\"Today we\u2019ll show you the research of Stefania Forner. 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She made two Alzheimer&#039;s graphical abstracts with tau and beta-amyloid effects in synaptic function.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/mindthegraph.com\/blog\/hu\/alzheimers-graphical-abstracts\/\" \/>\n<meta property=\"og:site_name\" content=\"Mind the Graph Blog\" \/>\n<meta property=\"article:published_time\" content=\"2017-06-21T20:35:04+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-10-18T11:29:23+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/mindthegraph.com\/blog\/wp-content\/uploads\/2017\/06\/alzheimers_final_flat.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"960\" \/>\n\t<meta property=\"og:image:height\" content=\"560\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Fabiola Soares\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Fabiola Soares\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Alzheimer's graphical abstracts: What's new in neuroscience in a visual way - Mind the Graph Blog","description":"Today we\u2019ll show you the research of Stefania Forner. 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